BR0312176A - Composto, composição farmaceutica, uso de um composto, método para o tratamento, método para reduzir a morbidez e a mortalidade associadas com o excesso de peso, processo para a preparação de um composto, novo intermediario e processo para a preparação de um novo intermediario - Google Patents
Composto, composição farmaceutica, uso de um composto, método para o tratamento, método para reduzir a morbidez e a mortalidade associadas com o excesso de peso, processo para a preparação de um composto, novo intermediario e processo para a preparação de um novo intermediarioInfo
- Publication number
- BR0312176A BR0312176A BR0312176-3A BR0312176A BR0312176A BR 0312176 A BR0312176 A BR 0312176A BR 0312176 A BR0312176 A BR 0312176A BR 0312176 A BR0312176 A BR 0312176A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- preparing
- new intermediate
- pharmaceutically acceptable
- overweight
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
"COMPOSTO, COMPOSIçãO FARMACêUTICA, USO DE UM COMPOSTO, MéTODO PARA O TRATAMENTO, MéTODO PARA REDUZIR A MORBIDEZ E A MORTALIDADE ASSOCIADAS COM O EXCESSO DE PESO, PROCESSO PARA A PREPARAçãO DE UM COMPOSTO, NOVO INTERMEDIáRIO E PROCESSO PARA A PREPARAçãO DE UM NOVO INTERMEDIáRIO". A presente invenção refere-se a indolos tetracíclicos de arilasulfonila, seus derivados, seus análogos, suas formas tautoméricas, seus estéreo isomêros, seus polimorfos, seus sais farmaceuticamente aceitáveis, seus solvatos farmaceuticamente aceitáveis, aos intermediários inovadores aqui descritos e às composições farmaceuticamente aceitáveis contendo os mesmos. A presente invenção está particularmente relacionada a novos indolos tetracíclicos de arilasulfonila tendo a fórmula geral (I), seus derivados, seus análogos, formas tautoméricas, seus estéreo isomêros, seus polimorfos, seus sais farmaceuticamente aceitáveis, seus solvatos farmaceuticamente aceitáveis, aos intermediários inovadores aqui descritos e às composições farmaceuticamente aceitáveis contendo os mesmos. A presente invenção também refere-se ao(s) processo(s) para a preparação de tal(is) composto(s) tendo a fórmula geral (I), às composições contendo quantidade(s) efetiva de referido composto e ao uso de tal composto/composição em terapias.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN478CH2002 | 2002-06-21 | ||
PCT/IN2003/000222 WO2004000849A2 (en) | 2002-06-21 | 2003-06-19 | Tetracyclic arylsulfonyl indoles having serotonin receptor affinity |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0312176A true BR0312176A (pt) | 2005-04-05 |
Family
ID=29798513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0312176-3A BR0312176A (pt) | 2002-06-21 | 2003-06-19 | Composto, composição farmaceutica, uso de um composto, método para o tratamento, método para reduzir a morbidez e a mortalidade associadas com o excesso de peso, processo para a preparação de um composto, novo intermediario e processo para a preparação de um novo intermediario |
Country Status (17)
Country | Link |
---|---|
US (1) | US7649097B2 (pt) |
EP (1) | EP1523486B1 (pt) |
JP (1) | JP4473120B2 (pt) |
CN (1) | CN100378108C (pt) |
AT (1) | ATE377603T1 (pt) |
AU (1) | AU2003249582B2 (pt) |
BR (1) | BR0312176A (pt) |
CA (1) | CA2490254C (pt) |
DE (1) | DE60317333T2 (pt) |
DK (1) | DK1523486T3 (pt) |
ES (1) | ES2297216T3 (pt) |
HK (1) | HK1074843A1 (pt) |
MX (1) | MXPA04012832A (pt) |
NZ (1) | NZ537770A (pt) |
RU (1) | RU2340619C2 (pt) |
WO (1) | WO2004000849A2 (pt) |
ZA (1) | ZA200409886B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1567492E (pt) | 2002-11-28 | 2013-07-22 | Suven Life Sciences Ltd | N-arilsulfonil-3-aminoalcoxi-indóis |
US7781476B2 (en) * | 2002-12-18 | 2010-08-24 | Suven Life Sciences Limited | Tetracyclic 3-substituted indoles having serotonin receptor affinity |
DE602004021031D1 (de) * | 2004-01-02 | 2009-06-18 | Suven Life Sciences Ltd | Neue indenoä2,1-aüindene und isoindolä2,1-aüindol |
WO2005094897A2 (en) * | 2004-04-01 | 2005-10-13 | Cardiome Pharma Corp. | Pegylated ion channel modulating compounds |
DE602005013702D1 (de) * | 2005-03-08 | 2009-05-14 | Suven Life Sciences Ltd | Verfahren zur herstellung substituierter benzothiazinoindole |
IL294202A (en) | 2019-12-26 | 2022-08-01 | Gilgamesh Pharmaceuticals Inc | History of arylcyclohexylamine and their use in the treatment of psychiatric disorders |
KR102567903B1 (ko) | 2020-02-18 | 2023-08-18 | 길가메쉬 파마슈티컬스, 인코포레이티드 | 기분 장애 치료에 사용되기 위한 특이적 트립타민 |
CN115667217A (zh) | 2020-05-19 | 2023-01-31 | 赛本爱尔兰有限公司 | 氘化的色胺衍生物和使用方法 |
CA3187020A1 (en) | 2020-06-12 | 2021-12-16 | Beckley Psytech Limited | Composition comprising a benzoate salt of 5-methoxy-n,n-dimethyltryptamine |
GB202212116D0 (en) | 2022-08-19 | 2022-10-05 | Beckley Psytech Ltd | Pharmaceutically acceptable salts and Compositions thereof |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3494920A (en) * | 1967-12-18 | 1970-02-10 | American Home Prod | 1-di(lower)alkylamino(lower)alkyl-3-(2-substituted ethyl) indoles |
ZA795239B (en) | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
BE889931A (fr) | 1980-08-12 | 1982-02-11 | Glaxo Group Ltd | Derives indoliques, leur preparation et leurs applications en tant que medicaments |
GB8600397D0 (en) | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
GB8719167D0 (en) | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
GB8724912D0 (en) | 1987-10-23 | 1987-11-25 | Wellcome Found | Indole derivatives |
GB8819024D0 (en) | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
IL96891A0 (en) | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
CA2042295A1 (fr) | 1990-05-15 | 1991-11-16 | Jacques Chauveau | Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant |
DE19775091I2 (de) | 1990-06-07 | 2007-05-24 | Astrazeneca Ab | Therapeutische heterocyclische Verbindungen |
CZ283018B6 (cs) | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
GB9113802D0 (en) | 1991-06-26 | 1991-08-14 | Smithkline Beecham Plc | Medicaments |
GB9210400D0 (en) | 1992-05-15 | 1992-07-01 | Merck Sharp & Dohme | Therapeutic agents |
KR940007001A (ko) | 1992-09-16 | 1994-04-26 | 최승주 | 새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제 |
JP2000026471A (ja) | 1998-07-10 | 2000-01-25 | Nippon Soda Co Ltd | 11−ホルミル−インドロ[1,2−b][1,2]ベンズイソチアゾールおよび農園芸用殺菌剤 |
GB9820113D0 (en) * | 1998-09-15 | 1998-11-11 | Merck Sharp & Dohme | Therapeutic agents |
PT1149078E (pt) * | 1998-12-11 | 2006-07-31 | Univ Virginia Commonwealth | Ligandos receptores de 5-ht6 selectivos |
ES2292758T3 (es) | 2001-03-29 | 2008-03-16 | Eli Lilly And Company | N-(2-ariletil) bencilaminas como antagonistas del receptor 5-ht6. |
-
2003
- 2003-06-19 AU AU2003249582A patent/AU2003249582B2/en not_active Ceased
- 2003-06-19 DE DE60317333T patent/DE60317333T2/de not_active Expired - Lifetime
- 2003-06-19 CA CA2490254A patent/CA2490254C/en not_active Expired - Fee Related
- 2003-06-19 EP EP03760857A patent/EP1523486B1/en not_active Expired - Lifetime
- 2003-06-19 BR BR0312176-3A patent/BR0312176A/pt not_active IP Right Cessation
- 2003-06-19 ES ES03760857T patent/ES2297216T3/es not_active Expired - Lifetime
- 2003-06-19 JP JP2004515418A patent/JP4473120B2/ja not_active Expired - Fee Related
- 2003-06-19 US US10/519,219 patent/US7649097B2/en not_active Expired - Fee Related
- 2003-06-19 CN CNB038146029A patent/CN100378108C/zh not_active Expired - Fee Related
- 2003-06-19 AT AT03760857T patent/ATE377603T1/de active
- 2003-06-19 WO PCT/IN2003/000222 patent/WO2004000849A2/en active IP Right Grant
- 2003-06-19 RU RU2005101344/04A patent/RU2340619C2/ru not_active IP Right Cessation
- 2003-06-19 MX MXPA04012832A patent/MXPA04012832A/es active IP Right Grant
- 2003-06-19 NZ NZ537770A patent/NZ537770A/en not_active IP Right Cessation
- 2003-06-19 DK DK03760857T patent/DK1523486T3/da active
-
2004
- 2004-12-07 ZA ZA200409886A patent/ZA200409886B/en unknown
-
2005
- 2005-10-06 HK HK05108865A patent/HK1074843A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US7649097B2 (en) | 2010-01-19 |
CN1662544A (zh) | 2005-08-31 |
JP2005535621A (ja) | 2005-11-24 |
EP1523486B1 (en) | 2007-11-07 |
ES2297216T3 (es) | 2008-05-01 |
DE60317333T2 (de) | 2008-08-28 |
CA2490254C (en) | 2011-11-01 |
DE60317333D1 (de) | 2007-12-20 |
HK1074843A1 (en) | 2005-11-25 |
JP4473120B2 (ja) | 2010-06-02 |
US20050203154A1 (en) | 2005-09-15 |
ZA200409886B (en) | 2006-07-26 |
AU2003249582B2 (en) | 2006-08-03 |
RU2340619C2 (ru) | 2008-12-10 |
WO2004000849A2 (en) | 2003-12-31 |
MXPA04012832A (es) | 2005-05-27 |
CN100378108C (zh) | 2008-04-02 |
AU2003249582A1 (en) | 2004-01-06 |
WO2004000849A3 (en) | 2004-03-25 |
ATE377603T1 (de) | 2007-11-15 |
CA2490254A1 (en) | 2003-12-31 |
NZ537770A (en) | 2007-03-30 |
EP1523486A2 (en) | 2005-04-20 |
DK1523486T3 (da) | 2008-03-03 |
RU2005101344A (ru) | 2005-08-20 |
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Legal Events
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/02/2020, OBSERVADAS AS CONDICOES LEGAIS. |
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B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 18A ANUIDADE. |
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B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2624 DE 20-04-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |