PT1149078E - Ligandos receptores de 5-ht6 selectivos - Google Patents
Ligandos receptores de 5-ht6 selectivosInfo
- Publication number
- PT1149078E PT1149078E PT99967248T PT99967248T PT1149078E PT 1149078 E PT1149078 E PT 1149078E PT 99967248 T PT99967248 T PT 99967248T PT 99967248 T PT99967248 T PT 99967248T PT 1149078 E PT1149078 E PT 1149078E
- Authority
- PT
- Portugal
- Prior art keywords
- selective
- receptor ligands
- receptors
- compounds
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Escalators And Moving Walkways (AREA)
- Electric Double-Layer Capacitors Or The Like (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Control Of High-Frequency Heating Circuits (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Conductive Materials (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11178798P | 1998-12-11 | 1998-12-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1149078E true PT1149078E (pt) | 2006-07-31 |
Family
ID=22340454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99967248T PT1149078E (pt) | 1998-12-11 | 1999-12-10 | Ligandos receptores de 5-ht6 selectivos |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1149078B1 (pt) |
| AT (1) | ATE319683T1 (pt) |
| AU (1) | AU767009B2 (pt) |
| CA (1) | CA2353962C (pt) |
| DE (1) | DE69930308T2 (pt) |
| DK (1) | DK1149078T3 (pt) |
| ES (1) | ES2260958T3 (pt) |
| MX (1) | MXPA01005905A (pt) |
| PT (1) | PT1149078E (pt) |
| WO (1) | WO2000034242A1 (pt) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03003397A (es) | 2000-10-20 | 2004-06-30 | Biovitrum Ab | N1-(bencensulfonil)indoles sustituidos en las posiciones 2-, 3-, 4-, o 5 y su uso en terapia. |
| EA007493B1 (ru) * | 2001-03-29 | 2006-10-27 | Эли Лилли Энд Компани | N-(2-арилэтил)бензиламины в качестве антагонистов 5-ht-рецептора |
| EP1859798B1 (en) * | 2001-03-29 | 2015-12-30 | Eli Lilly And Company | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor |
| WO2002100822A1 (en) | 2001-06-11 | 2002-12-19 | Biovitrum Ab | Substituted sulfonamide compounds, process for their use as medicament for the treatment of cns disorders, obesity and type ii diabetes |
| ITRM20010356A1 (it) * | 2001-06-21 | 2002-12-23 | Sigma Tau Ind Farmaceuti | "5-alogeno derivati della triptamina utili come ligandi del recettore5-ht6 e/o 5-ht7 della serotonina. |
| EP1897881A3 (en) | 2002-06-20 | 2009-03-18 | Biovitrum AB (publ) | Compounds useful for the treatment of obesity, type II diabetes and CNS disorders |
| ATE377603T1 (de) * | 2002-06-21 | 2007-11-15 | Suven Life Sciences Ltd | Tetracyklische arylsulfonylindole mit affinität zum serotonin rezeptor |
| US7781476B2 (en) * | 2002-12-18 | 2010-08-24 | Suven Life Sciences Limited | Tetracyclic 3-substituted indoles having serotonin receptor affinity |
| NZ544298A (en) | 2003-06-26 | 2009-04-30 | Takeda Pharmaceutical | Cannabinoid receptor modulators including benzofuran derivatives |
| DK1648904T3 (da) * | 2003-07-31 | 2007-10-22 | Wyeth Corp | N-sulfonylheterocyclopyrrolalkylaminforbindelser som 5-hydroxytryptamin-6-ligander |
| SE0303480D0 (sv) | 2003-12-19 | 2003-12-19 | Biovitrum Ab | Benzofuranes |
| MX2007005199A (es) | 2004-11-01 | 2007-05-11 | Wyeth Corp | Indolizinas sustituidas y derivados como agentes del sistema nervioso central. |
| US7582767B2 (en) | 2005-06-17 | 2009-09-01 | Biovitrum Ab (Publ.) | Substituted sulphonamide compound and uses thereof |
| EA014694B1 (ru) * | 2005-10-19 | 2010-12-30 | Сувен Лайф Сайенсиз Лимитед | Производные карбазола в качестве функциональных 5-htлигандов |
| EP2134714A1 (en) | 2007-03-13 | 2009-12-23 | Biovitrum AB (publ) | Tricyclic isoquinoline derivatives for treatment of obesity |
| US8138219B2 (en) | 2007-12-04 | 2012-03-20 | Merck Sharp & Dohme Corp. | Tryptamine sulfonamides as 5-HT6 antagonists |
| EP2103596A1 (en) | 2008-03-18 | 2009-09-23 | Laboratorios Del. Dr. Esteve, S.A. | Process for the preparation of N-(phenylethyl) anilines salts and solvates thereof useful as serotonin 5-HT6 antagonists |
| GB0905328D0 (en) * | 2009-03-27 | 2009-05-13 | Ge Healthcare Ltd | Indole derivatives |
| FR2961097B1 (fr) * | 2010-06-09 | 2012-07-13 | Oreal | Procede cosmetique de traitement des odeurs corporelles humaines utilisant un compose 6-alkoxy tryptamine |
| FR2961095B1 (fr) * | 2010-06-09 | 2012-06-15 | Oreal | Composition cosmetique et/ou dermatologique comprenant au moins un compose 6-alcoxy tryptamine |
| EP2771341A4 (en) | 2011-10-28 | 2015-09-23 | Univ Texas | NEW COMPOSITIONS AND METHOD FOR THE TREATMENT OF CANCER |
| JO3459B1 (ar) | 2012-09-09 | 2020-07-05 | H Lundbeck As | تركيبات صيدلانية لعلاج مرض الزهايمر |
| EP4153564A4 (en) | 2020-05-19 | 2024-06-19 | Cybin IRL Limited | DEUTERATED TRYPTAMINE DERIVATIVES AND METHODS OF USE |
| WO2023115167A1 (en) * | 2021-12-24 | 2023-06-29 | Psylo Pty Ltd | Compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3939177A (en) * | 1972-11-22 | 1976-02-17 | Sterling Drug Inc. | 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles |
| GB8416724D0 (en) * | 1984-06-30 | 1984-08-01 | Sorbio Sa Lab | Active compounds |
-
1999
- 1999-12-10 WO PCT/US1999/029219 patent/WO2000034242A1/en active IP Right Grant
- 1999-12-10 CA CA002353962A patent/CA2353962C/en not_active Expired - Fee Related
- 1999-12-10 MX MXPA01005905A patent/MXPA01005905A/es not_active IP Right Cessation
- 1999-12-10 DK DK99967248T patent/DK1149078T3/da active
- 1999-12-10 AU AU23562/00A patent/AU767009B2/en not_active Ceased
- 1999-12-10 DE DE69930308T patent/DE69930308T2/de not_active Expired - Fee Related
- 1999-12-10 ES ES99967248T patent/ES2260958T3/es not_active Expired - Lifetime
- 1999-12-10 PT PT99967248T patent/PT1149078E/pt unknown
- 1999-12-10 EP EP99967248A patent/EP1149078B1/en not_active Expired - Lifetime
- 1999-12-10 AT AT99967248T patent/ATE319683T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2353962A1 (en) | 2000-06-15 |
| AU767009B2 (en) | 2003-10-30 |
| EP1149078A1 (en) | 2001-10-31 |
| EP1149078A4 (en) | 2003-01-29 |
| AU2356200A (en) | 2000-06-26 |
| ES2260958T3 (es) | 2006-11-01 |
| DK1149078T3 (da) | 2006-07-10 |
| WO2000034242A1 (en) | 2000-06-15 |
| CA2353962C (en) | 2009-09-29 |
| DE69930308D1 (de) | 2006-05-04 |
| MXPA01005905A (es) | 2002-09-18 |
| DE69930308T2 (de) | 2006-11-30 |
| ATE319683T1 (de) | 2006-03-15 |
| EP1149078B1 (en) | 2006-03-08 |
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