FI870062A - Kemiska foereningar. - Google Patents

Kemiska foereningar. Download PDF

Info

Publication number
FI870062A
FI870062A FI870062A FI870062A FI870062A FI 870062 A FI870062 A FI 870062A FI 870062 A FI870062 A FI 870062A FI 870062 A FI870062 A FI 870062A FI 870062 A FI870062 A FI 870062A
Authority
FI
Finland
Prior art keywords
foereningar
chemical
chemical foereningar
Prior art date
Application number
FI870062A
Other languages
English (en)
Other versions
FI870062A0 (fi
Inventor
Keith Mills
David Eldred Colin
Alexander William Oxford
Ian Harold Coates
David Edmund Bays
Colin Frederick Webb
Michael Dennis Dowle
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FI870062A0 publication Critical patent/FI870062A0/fi
Publication of FI870062A publication Critical patent/FI870062A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI870062A 1986-01-08 1987-01-08 Kemiska foereningar. FI870062A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868600397A GB8600397D0 (en) 1986-01-08 1986-01-08 Chemical compounds

Publications (2)

Publication Number Publication Date
FI870062A0 FI870062A0 (fi) 1987-01-08
FI870062A true FI870062A (fi) 1987-07-09

Family

ID=10591074

Family Applications (1)

Application Number Title Priority Date Filing Date
FI870062A FI870062A (fi) 1986-01-08 1987-01-08 Kemiska foereningar.

Country Status (23)

Country Link
US (1) US4855314A (fi)
EP (1) EP0240096A1 (fi)
JP (1) JPS62228056A (fi)
KR (1) KR870007116A (fi)
CN (1) CN1030409A (fi)
AU (1) AU597325B2 (fi)
BE (1) BE1000071A4 (fi)
CH (1) CH672637A5 (fi)
DE (1) DE3700408A1 (fi)
DK (1) DK8787A (fi)
FI (1) FI870062A (fi)
FR (1) FR2595351B1 (fi)
GB (2) GB8600397D0 (fi)
HU (1) HU198685B (fi)
IL (1) IL81201A (fi)
IT (1) IT1205849B (fi)
LU (1) LU86732A1 (fi)
NL (1) NL8700026A (fi)
NO (1) NO870075L (fi)
NZ (1) NZ218868A (fi)
PH (1) PH24741A (fi)
PT (1) PT84075B (fi)
ZA (1) ZA87105B (fi)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8823731D0 (en) * 1988-10-10 1988-11-16 Smith Kline French Lab Biologically active compounds
AU646871B2 (en) * 1990-06-07 1994-03-10 Astrazeneca Uk Limited Therapeutic heterocyclic compounds
RO111767B1 (ro) * 1990-10-15 1997-01-30 Pfizer Derivati de indol, procedee si intermediari pentru prepararea acestora, compozitii farmaceutice si metoda pentru tratarea unor afectiuni
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
CA2061520C (en) * 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
UA41297C2 (uk) * 1991-11-25 2001-09-17 Пфайзер, Інк. Похідні індолу, фармацевтична композиція і спосіб лікування
TW288010B (fi) * 1992-03-05 1996-10-11 Pfizer
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
BR9306201A (pt) * 1992-04-07 1998-06-23 Pfizer Derivados de indol como agonistas 5-ht1
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
ATE148465T1 (de) * 1992-04-10 1997-02-15 Pfizer Acylaminoindolderivate als 5-ht1 agonisten
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
TW251284B (fi) * 1992-11-02 1995-07-11 Pfizer
FR2707639B1 (fr) * 1993-06-30 1995-10-13 Pf Medicament Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
EP0716649B1 (en) * 1993-08-31 1998-09-09 Pfizer Inc. 5-arylindole derivatives
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
FR2749846B1 (fr) * 1996-06-17 1998-09-11 Pf Medicament Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
ATE328868T1 (de) * 2000-08-21 2006-06-15 Pacific Corp Neue (thio)harnstoffverbindungen und arzneimittelkompositionen, die diese enthalten
DK1537113T5 (da) * 2002-06-21 2011-01-10 Suven Life Sciences Ltd Arylalkylindoler med serotoninreceptoraffinitet anvendelige som terapeutiske midler, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
MXPA04012836A (es) 2002-06-21 2005-04-25 Suven Life Sciences Ltd Arilcarbonil indoles tetraciclicos novedosos que tienen afinidad por el receptor de la serotonina, utiles como agentes terapeuticos, proceso para su preparacion y composiciones farmaceuticas que los contienen.
EP1523486B1 (en) * 2002-06-21 2007-11-07 Suven Life Sciences Limited Tetracyclic arylsulfonyl indoles having serotonin receptor affinity
DK1581492T3 (da) * 2002-11-28 2008-11-10 Suven Life Sciences Ltd N-arylsulfonyl-3-substituerede indoler med serotoninreceptoraffinitet, fremgangsmåde til fremstilling heraf og en farmaceutisk sammensætning indeholdende disse
ES2425143T3 (es) 2002-11-28 2013-10-11 Suven Life Sciences Limited N-Arilsulfonil-3-aminoalcoxiindoles
EA009367B1 (ru) * 2002-12-18 2007-12-28 Сувен Лайф Сайенсиз Лимитед ПРОИЗВОДНЫЕ 5-ТИА-5-ДИОКСО-4b-АЗАИНДЕНО[2,1-a]ИНДЕНА, ОБЛАДАЮЩИЕ АФФИННОСТЬЮ К РЕЦЕПТОРУ СЕРОТОНИНА
CA2508290C (en) 2002-12-20 2017-02-28 Ciba Specialty Chemicals Holding Inc. Synthesis of amines and intermediates for the synthesis thereof
KR20090026282A (ko) 2006-06-12 2009-03-12 노파르티스 아게 Ｎ-히드록시-３-[４-[[[２-(２-메틸-1ｈ-인돌-３-일)에틸]아미노]메틸]페닐]-2ｅ-２-프로펜아미드의 염을 제조하는 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472870A (en) * 1966-08-29 1969-10-14 Mead Johnson & Co Sulfonamidotryptamines
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
NL8103764A (nl) * 1980-08-12 1982-03-01 Glaxo Group Ltd Heterocyclische verbindingen, werkwijze ter bereiding daarvan, alsmede farmaceutische preparaten die deze verbindingen als actieve component bevatten.
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds
HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
FR2595351A1 (fr) 1987-09-11
IT8747507A0 (it) 1987-01-08
HUT46891A (en) 1988-12-28
DE3700408A1 (de) 1987-07-09
KR870007116A (ko) 1987-08-14
GB2185020A (en) 1987-07-08
IL81201A (en) 1991-06-10
LU86732A1 (fr) 1988-02-02
GB8700382D0 (en) 1987-02-11
ZA87105B (en) 1987-09-30
DK8787D0 (da) 1987-01-08
PT84075B (pt) 1989-07-31
CN1030409A (zh) 1989-01-18
CH672637A5 (fi) 1989-12-15
AU597325B2 (en) 1990-05-31
IL81201A0 (en) 1987-08-31
NL8700026A (nl) 1987-08-03
DK8787A (da) 1987-07-09
GB2185020B (en) 1990-05-16
PT84075A (en) 1987-02-01
PH24741A (en) 1990-10-01
IT1205849B (it) 1989-03-31
BE1000071A4 (fr) 1988-02-02
GB8600397D0 (en) 1986-02-12
JPS62228056A (ja) 1987-10-06
HU198685B (en) 1989-11-28
EP0240096A1 (en) 1987-10-07
NZ218868A (en) 1990-04-26
US4855314A (en) 1989-08-08
NO870075L (no) 1987-07-09
AU6742087A (en) 1987-07-09
FI870062A0 (fi) 1987-01-08
NO870075D0 (no) 1987-01-08
FR2595351B1 (fr) 1990-07-13

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Owner name: GLAXO GROUP LIMITED