PH24738A - Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines - Google Patents

Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines

Info

Publication number
PH24738A
PH24738A PH34794A PH34794A PH24738A PH 24738 A PH24738 A PH 24738A PH 34794 A PH34794 A PH 34794A PH 34794 A PH34794 A PH 34794A PH 24738 A PH24738 A PH 24738A
Authority
PH
Philippines
Prior art keywords
alkyl
substd
alkoxy
furanyl
opt
Prior art date
Application number
PH34794A
Other languages
English (en)
Inventor
Frans Eduard Janssens
Josef Francis Hens
Joseph Leo Ghislanus Torremans
Josef Jan Pieter Heykants
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PH24738A publication Critical patent/PH24738A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PH34794A 1986-02-03 1987-01-30 Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines PH24738A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82549186A 1986-02-03 1986-02-03

Publications (1)

Publication Number Publication Date
PH24738A true PH24738A (en) 1990-10-01

Family

ID=25244134

Family Applications (1)

Application Number Title Priority Date Filing Date
PH34794A PH24738A (en) 1986-02-03 1987-01-30 Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines

Country Status (26)

Country Link
EP (1) EP0232937B1 (fr)
JP (2) JPH0794393B2 (fr)
CN (1) CN1018614B (fr)
AT (1) ATE79620T1 (fr)
AU (1) AU583706B2 (fr)
CA (1) CA1327579C (fr)
CY (1) CY1865A (fr)
DE (1) DE3781173T2 (fr)
DK (1) DK173674B1 (fr)
EG (1) EG17993A (fr)
ES (1) ES2052544T3 (fr)
FI (1) FI870448A (fr)
GR (1) GR3006158T3 (fr)
HK (1) HK114695A (fr)
HU (1) HU201067B (fr)
IE (1) IE60885B1 (fr)
IL (1) IL81448A (fr)
MA (1) MA20868A1 (fr)
NO (1) NO870407L (fr)
NZ (1) NZ219165A (fr)
PH (1) PH24738A (fr)
PT (1) PT84234B (fr)
TN (1) TNSN87015A1 (fr)
ZA (1) ZA87744B (fr)
ZM (1) ZM1287A1 (fr)
ZW (1) ZW2087A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ223654A (en) * 1987-03-09 1990-03-27 Janssen Pharmaceutica Nv 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
US4897401A (en) * 1987-06-19 1990-01-30 Janssen Pharmaceutical N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases
CA1317939C (fr) * 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap Hexahydro-1h-azepines et pyrrolidines a substitution par des ((heterocyclyle bicyclique) methyle et -hetero
US4988689A (en) * 1987-07-01 1991-01-29 Janssen Pharmaceutica N.V. ((Pharmacologically active bicyclic heterocyclic)methyl and -heteroatom) substituted hexahydro-1H-azepines and pyrrolidines
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
IT1229231B (it) * 1989-05-08 1991-07-26 Dompe Farmaceutici Spa Aminoimidazopiridine farmacologicamente attive
CA2043564A1 (fr) * 1990-07-06 1992-01-07 Alfons G. M. De Knaep 3-[(5-methyl-2-furyl)methyl]-n-(4-piperidyl)-3h-imidazo[4,5-b]pyridin-2-amine 2-hydroxypropane-1,2,3-tricarboxylate
NZ239540A (en) * 1990-09-24 1993-11-25 Neurosearch As 1-phenyl benzimidazole derivatives and medicaments
DE69327328T2 (de) * 1992-09-03 2000-06-21 Sepracor Inc., Marlborough Verwendund von norastemizol zur behandlung der allergischen rhinitis
AU730229B2 (en) * 1992-09-03 2001-03-01 Sepracor, Inc. Use of norastemizole for the treatment of allergic disorders
EP0699668A4 (fr) * 1993-05-20 1996-09-18 Kissei Pharmaceutical Derive 1-(2-benzimidazolyl)-1,5-diazacyclooctane
TW429256B (en) * 1995-12-27 2001-04-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(benzimidazolyl- and imidazopyridinyl)-piperidine derivatives
BR9808428A (pt) * 1997-03-26 2000-05-23 Sepracor Inc Composição farmacêutica, processo para tratar distúrbios alérgicos em um mamìfero e forma de dosagem unitária sólida
US5817823A (en) * 1997-04-17 1998-10-06 Sepracor Inc. Method for synthesizing 2-substituted imidazoles
EA004939B1 (ru) 1999-06-28 2004-10-28 Янссен Фармацевтика Н.В. Ингибиторы репликации респираторно-синцитиального вируса
EE04591B1 (et) 1999-06-28 2006-02-15 Janssen Pharmaceutica N.V. Respiratoorse süntsütiaalviiruse replikatsiooni inhibiitorid, nende valmistamismeetod, kasutamine ja vaheühendid, farmatseutiline kompositsioon ja selle valmistamismeetod ning produkt
TR200500707T2 (tr) 1999-06-28 2005-04-21 Janssen Pharmaceutica N.V. Solunum sistemi sinsitiyal virüsünün replikasyonunu inhibe edici maddeler.
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
US20070021404A1 (en) * 2003-06-24 2007-01-25 Dan Peters Novel aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
NZ548074A (en) 2003-12-22 2010-08-27 Gerhard Puerstinger Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
EP1841765B1 (fr) 2004-12-21 2009-03-25 Gilead Sciences, Inc. Compose d'imidazo[4,5-c]pyridine et traitement antiviral dans lequel est utilise ledit compose
EP1838706A1 (fr) 2004-12-24 2007-10-03 Prosidion Limited Agonistes du récepteur couplé aux protéines g
DE602006016244D1 (de) 2005-03-08 2010-09-30 Janssen Pharmaceutica Nv Diazaspiro-ä4,4ü-nonanderivate als neurokinin-(nk1)-antagonisten
SG175604A1 (en) 2006-07-07 2011-11-28 Gilead Sciences Inc Novel pyridazine compound and use thereof
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
MX2011003239A (es) * 2008-09-26 2011-04-28 Merck Sharp & Dohme Nuevos derivados de bencimidazol ciclicos utiles como agentes anti-diabeticos.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1140119A (fr) * 1978-04-03 1983-01-25 Joseph Torremans Nouvelles n-heterocycle-4-piperidinamines
US4219559A (en) 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
IN156065B (fr) * 1982-07-12 1985-05-04 Janssen Pharmaceutica Nv
US4556660A (en) * 1982-07-12 1985-12-03 Janssen Pharmaceutica N.V. N-(Bicyclic heterocyclyl)-4-piperidinamines
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
EP0144101B1 (fr) * 1983-11-30 1991-02-06 Janssen Pharmaceutica N.V. N-(Hétérocycle bicyclyl)-4-pipéridinamines contenant des hétérocycles bicycliques
US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
JPS60174778A (ja) * 1984-01-09 1985-09-09 ジヤンセン・フア−マシユ−チカ・ナ−ムロ−ゼ・フエンノ−トシヤツプ Ｎ−ヘテロシクリル−４−ピペリジンアミン
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines

Also Published As

Publication number Publication date
CN1018614B (zh) 1992-10-14
DK54187D0 (da) 1987-02-02
ES2052544T3 (es) 1994-07-16
EG17993A (en) 1991-08-30
TNSN87015A1 (fr) 1990-01-01
NO870407L (no) 1987-08-04
IL81448A (en) 1990-09-17
ZA87744B (en) 1988-10-26
HK114695A (en) 1995-07-21
GR3006158T3 (fr) 1993-06-21
IE870258L (en) 1987-08-03
JPH0819126B2 (ja) 1996-02-28
DE3781173D1 (de) 1992-09-24
MA20868A1 (fr) 1987-10-01
PT84234B (pt) 1989-09-14
JPS62215575A (ja) 1987-09-22
EP0232937A2 (fr) 1987-08-19
EP0232937A3 (en) 1988-04-06
EP0232937B1 (fr) 1992-08-19
JPH07179458A (ja) 1995-07-18
DK54187A (da) 1987-08-04
NZ219165A (en) 1990-04-26
IE60885B1 (en) 1994-08-24
HUT44544A (en) 1988-03-28
CA1327579C (fr) 1994-03-08
CN87100563A (zh) 1987-08-19
HU201067B (en) 1990-09-28
DK173674B1 (da) 2001-06-05
JPH0794393B2 (ja) 1995-10-11
DE3781173T2 (de) 1992-12-17
CY1865A (en) 1996-04-05
ZM1287A1 (en) 1988-08-29
FI870448A0 (fi) 1987-02-02
AU583706B2 (en) 1989-05-04
AU6821887A (en) 1987-08-06
ATE79620T1 (de) 1992-09-15
NO870407D0 (no) 1987-02-02
IL81448A0 (en) 1987-09-16
ZW2087A1 (en) 1988-08-31
PT84234A (en) 1987-03-01
FI870448A (fi) 1987-08-04

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