DK54187A - Antiallergiske praeparater indeholdende n-heterocyklyl-4-piperidinaminer - Google Patents

Antiallergiske praeparater indeholdende n-heterocyklyl-4-piperidinaminer

Info

Publication number
DK54187A
DK54187A DK054187A DK54187A DK54187A DK 54187 A DK54187 A DK 54187A DK 054187 A DK054187 A DK 054187A DK 54187 A DK54187 A DK 54187A DK 54187 A DK54187 A DK 54187A
Authority
DK
Denmark
Prior art keywords
alkyl
substd
alkoxy
furanyl
opt
Prior art date
Application number
DK054187A
Other languages
English (en)
Other versions
DK173674B1 (da
DK54187D0 (da
Inventor
Frans Eduard Janssens
Jozef Francis Hens
Joseph Leo Ghislanus Torremans
Jozef Jan Pieter Heykants
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of DK54187D0 publication Critical patent/DK54187D0/da
Publication of DK54187A publication Critical patent/DK54187A/da
Application granted granted Critical
Publication of DK173674B1 publication Critical patent/DK173674B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK198700541A 1986-02-03 1987-02-02 Anti-allergiske præparater indeholdende N-heterocyclyl-4-piperidinaminer, N-heterocyclyl-4-piperidinaminer til brug som antiallergikum og hidtil ukendte N-heterocyclyl-4-piperidinaminer samt fremgangsmåde til fremstilling deraf DK173674B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82549186A 1986-02-03 1986-02-03
US82549186 1986-02-03

Publications (3)

Publication Number Publication Date
DK54187D0 DK54187D0 (da) 1987-02-02
DK54187A true DK54187A (da) 1987-08-04
DK173674B1 DK173674B1 (da) 2001-06-05

Family

ID=25244134

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198700541A DK173674B1 (da) 1986-02-03 1987-02-02 Anti-allergiske præparater indeholdende N-heterocyclyl-4-piperidinaminer, N-heterocyclyl-4-piperidinaminer til brug som antiallergikum og hidtil ukendte N-heterocyclyl-4-piperidinaminer samt fremgangsmåde til fremstilling deraf

Country Status (26)

Country Link
EP (1) EP0232937B1 (da)
JP (2) JPH0794393B2 (da)
CN (1) CN1018614B (da)
AT (1) ATE79620T1 (da)
AU (1) AU583706B2 (da)
CA (1) CA1327579C (da)
CY (1) CY1865A (da)
DE (1) DE3781173T2 (da)
DK (1) DK173674B1 (da)
EG (1) EG17993A (da)
ES (1) ES2052544T3 (da)
FI (1) FI870448A (da)
GR (1) GR3006158T3 (da)
HK (1) HK114695A (da)
HU (1) HU201067B (da)
IE (1) IE60885B1 (da)
IL (1) IL81448A (da)
MA (1) MA20868A1 (da)
NO (1) NO870407L (da)
NZ (1) NZ219165A (da)
PH (1) PH24738A (da)
PT (1) PT84234B (da)
TN (1) TNSN87015A1 (da)
ZA (1) ZA87744B (da)
ZM (1) ZM1287A1 (da)
ZW (1) ZW2087A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ223654A (en) * 1987-03-09 1990-03-27 Janssen Pharmaceutica Nv 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
US4897401A (en) * 1987-06-19 1990-01-30 Janssen Pharmaceutical N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases
US4988689A (en) * 1987-07-01 1991-01-29 Janssen Pharmaceutica N.V. ((Pharmacologically active bicyclic heterocyclic)methyl and -heteroatom) substituted hexahydro-1H-azepines and pyrrolidines
CA1317939C (en) * 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
IT1229231B (it) * 1989-05-08 1991-07-26 Dompe Farmaceutici Spa Aminoimidazopiridine farmacologicamente attive
CA2043564A1 (en) * 1990-07-06 1992-01-07 Alfons G. M. De Knaep 3-[(5-methyl-2-furanyl)methyl]-n-(4-piperidinyl)-3h-imidazo [4,5-b]-pyridin-2-amine 2-hydroxy-1,2,3-propanetricarboxylate
NZ239540A (en) * 1990-09-24 1993-11-25 Neurosearch As 1-phenyl benzimidazole derivatives and medicaments
DE4394931T1 (de) * 1992-09-03 1995-07-20 Sepracor Inc Verwendung von Norastemizol zur Behandlung von allergischen Erkrankungen
AU730229B2 (en) * 1992-09-03 2001-03-01 Sepracor, Inc. Use of norastemizole for the treatment of allergic disorders
EP0699668A4 (en) * 1993-05-20 1996-09-18 Kissei Pharmaceutical DERIVATIVE 1- (2-BENZIMIDAZOLYL) -1,5-DIAZACYCLOOCTANE
TW429256B (en) * 1995-12-27 2001-04-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(benzimidazolyl- and imidazopyridinyl)-piperidine derivatives
WO1998042379A2 (en) * 1997-03-26 1998-10-01 Sepracor Inc. Chemically and thermally stable norastemizole formulations
US5817823A (en) * 1997-04-17 1998-10-06 Sepracor Inc. Method for synthesizing 2-substituted imidazoles
DE60033859T2 (de) 1999-06-28 2007-11-08 Janssen Pharmaceutica N.V. Hemmer des Respiratorischen Syncytial Virus
AU778218B2 (en) * 1999-06-28 2004-11-25 Janssen Pharmaceutica N.V. Respiratory syncytial virus replication inhibitors
CZ20014574A3 (cs) * 1999-06-28 2002-05-15 Janssen Pharmaceutica N. V. Inhibitory replikace respiračně syncyciálního viru
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
US20070021404A1 (en) * 2003-06-24 2007-01-25 Dan Peters Novel aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
EP1706403B9 (en) 2003-12-22 2012-07-25 K.U.Leuven Research & Development Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
SI1841765T1 (sl) 2004-12-21 2009-08-31 Gilead Sciences Inc Imidazo(4,5-c)piridinska spojina in postopek za antivirusno zdravljenje
WO2006067532A1 (en) 2004-12-24 2006-06-29 Prosidion Ltd G-protein coupled receptor agonists
EP1858896B1 (en) 2005-03-08 2010-08-18 Janssen Pharmaceutica NV Diaza-spiro-[4.4]-nonane derivatives as neurokinin (nk1) antagonists
MX2009000235A (es) 2006-07-07 2009-01-23 Gilead Sciences Inc Compuesto de piridazina novedoso y uso del mismo.
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
AU2009296820B2 (en) * 2008-09-26 2014-03-20 Merck Sharp & Dohme Llc Novel cyclic benzimidazole derivatives useful anti-diabetic agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4219559A (en) 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
CA1140119A (en) * 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
IN156065B (da) * 1982-07-12 1985-05-04 Janssen Pharmaceutica Nv
US4556660A (en) * 1982-07-12 1985-12-03 Janssen Pharmaceutica N.V. N-(Bicyclic heterocyclyl)-4-piperidinamines
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
EP0144101B1 (en) * 1983-11-30 1991-02-06 Janssen Pharmaceutica N.V. Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines
PL144514B1 (en) * 1984-01-09 1988-06-30 Janssen Pharmaceutica Nv Method of obtaining novel derivatives of n-/4-piperidinolo/-2-imidazoloamine
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives

Also Published As

Publication number Publication date
CA1327579C (en) 1994-03-08
ZA87744B (en) 1988-10-26
NO870407L (no) 1987-08-04
DK173674B1 (da) 2001-06-05
MA20868A1 (fr) 1987-10-01
ZM1287A1 (en) 1988-08-29
HU201067B (en) 1990-09-28
PH24738A (en) 1990-10-01
CN1018614B (zh) 1992-10-14
AU6821887A (en) 1987-08-06
GR3006158T3 (da) 1993-06-21
AU583706B2 (en) 1989-05-04
EP0232937A2 (en) 1987-08-19
CN87100563A (zh) 1987-08-19
EP0232937A3 (en) 1988-04-06
HK114695A (en) 1995-07-21
PT84234B (pt) 1989-09-14
FI870448A0 (fi) 1987-02-02
CY1865A (en) 1996-04-05
IE60885B1 (en) 1994-08-24
JPS62215575A (ja) 1987-09-22
EG17993A (en) 1991-08-30
IL81448A0 (en) 1987-09-16
PT84234A (en) 1987-03-01
NZ219165A (en) 1990-04-26
DK54187D0 (da) 1987-02-02
JPH07179458A (ja) 1995-07-18
JPH0794393B2 (ja) 1995-10-11
FI870448A (fi) 1987-08-04
EP0232937B1 (en) 1992-08-19
ZW2087A1 (en) 1988-08-31
HUT44544A (en) 1988-03-28
DE3781173D1 (de) 1992-09-24
NO870407D0 (no) 1987-02-02
IE870258L (en) 1987-08-03
DE3781173T2 (de) 1992-12-17
TNSN87015A1 (fr) 1990-01-01
ES2052544T3 (es) 1994-07-16
JPH0819126B2 (ja) 1996-02-28
IL81448A (en) 1990-09-17
ATE79620T1 (de) 1992-09-15

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired