PH24073A - Substituted 2-(2-aminobenzylthio)benzimidazole derivatives the corresponding sulfoxides and sulfones,a process for their preparation,pharmaceutical composition containing them and their use as inhibitors of gastric acid secretion - Google Patents
Substituted 2-(2-aminobenzylthio)benzimidazole derivatives the corresponding sulfoxides and sulfones,a process for their preparation,pharmaceutical composition containing them and their use as inhibitors of gastric acid secretionInfo
- Publication number
- PH24073A PH24073A PH34172A PH34172A PH24073A PH 24073 A PH24073 A PH 24073A PH 34172 A PH34172 A PH 34172A PH 34172 A PH34172 A PH 34172A PH 24073 A PH24073 A PH 24073A
- Authority
- PH
- Philippines
- Prior art keywords
- aminobenzylthio
- sulfones
- inhibitors
- substituted
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19853530342 DE3530342A1 (de) | 1985-08-24 | 1985-08-24 | Substituierte toluidine, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
DE19863610609 DE3610609A1 (de) | 1986-03-29 | 1986-03-29 | Substituierte toluidine, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
Publications (1)
Publication Number | Publication Date |
---|---|
PH24073A true PH24073A (en) | 1990-03-05 |
Family
ID=25835350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH34172A PH24073A (en) | 1985-08-24 | 1986-08-22 | Substituted 2-(2-aminobenzylthio)benzimidazole derivatives the corresponding sulfoxides and sulfones,a process for their preparation,pharmaceutical composition containing them and their use as inhibitors of gastric acid secretion |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0213474B1 (pt) |
JP (1) | JPH0791276B2 (pt) |
KR (1) | KR940005020B1 (pt) |
AR (1) | AR243167A1 (pt) |
AT (1) | ATE85328T1 (pt) |
DE (1) | DE3687675D1 (pt) |
DK (1) | DK401586A (pt) |
ES (1) | ES2001389A6 (pt) |
FI (1) | FI89910C (pt) |
GR (1) | GR862180B (pt) |
HU (1) | HU199126B (pt) |
IE (1) | IE59587B1 (pt) |
IL (1) | IL79813A0 (pt) |
NO (1) | NO169169C (pt) |
NZ (1) | NZ217322A (pt) |
PH (1) | PH24073A (pt) |
PT (1) | PT83240B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0239129B1 (en) | 1986-03-28 | 1991-09-25 | Otsuka Pharmaceutical Co., Ltd. | Hydroquinoline compounds, compositions containing same and processes for preparing same |
EP0251536A1 (en) * | 1986-06-24 | 1988-01-07 | FISONS plc | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors |
IT1222412B (it) * | 1987-07-31 | 1990-09-05 | Chiesi Farma Spa | Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono |
CA1322005C (en) * | 1987-11-25 | 1993-09-07 | Robert N. Young | Benzoheterazoles |
EP0318085A3 (en) * | 1987-11-25 | 1990-03-14 | Merck Frosst Canada Inc. | Heterazole dialkanoic acids |
JP2564162B2 (ja) * | 1988-02-12 | 1996-12-18 | 日本ケミファ株式会社 | ベンズイミダゾール誘導体の四級塩 |
ES2047451B1 (es) * | 1992-07-10 | 1994-10-01 | Sint Quimica Sa | Procedimiento para la preparacion de una composicion farmaceutica oral estable. |
KR20040028815A (ko) * | 2004-01-07 | 2004-04-03 | 화인고무(주) | 접착제를 사용하지 않는 사출 및 열융착을 가능하게하는인조피혁 |
CN115433167B (zh) * | 2022-11-10 | 2023-03-24 | 中国药科大学 | 具有Snail抑制活性的苯并杂环类化合物、其制备方法、药物组合物和医药用途 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE332167C (de) | 1918-08-09 | 1921-01-26 | Chem Fab Vorm Goldenberg | Glyzerinersatz |
BE788805A (fr) | 1971-09-22 | 1973-01-02 | Lafon Victor | Nouveaux derives antalgiques de la serie des arylamines soufrees |
SE416649B (sv) | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
IL66340A (en) * | 1981-08-13 | 1986-08-31 | Haessle Ab | Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation |
US4472409A (en) | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
DE3333314A1 (de) | 1983-09-15 | 1985-03-28 | Hoechst Ag, 6230 Frankfurt | Substituierte pyrido(1,2-c)imidazo(1,2-a)benzimidazole, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
GB8417271D0 (en) * | 1984-07-06 | 1984-08-08 | Fisons Plc | Biologically active nitrogen heterocycles |
DE3585252D1 (de) * | 1984-07-06 | 1992-03-05 | Fisons Plc | Benzimidazole, und verfahren zu deren herstellung, deren formulierung und verwendung als magensaeuresekretionshemmende verbindungen. |
AU4640985A (en) * | 1984-08-31 | 1986-03-06 | Nippon Chemiphar Co. Ltd. | Benzimidazole derivatives |
DE3509333A1 (de) | 1985-03-15 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Substituierte benzimidazolderivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
EP0204215B1 (en) * | 1985-05-24 | 1993-08-11 | G.D. Searle & Co. | 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-benzenamines |
EP0232399A1 (de) * | 1985-08-21 | 1987-08-19 | Byk Gulden Lomberg Chemische Fabrik GmbH | Neue amine, verfahren zu ihrer herstellung, ihre anwendung und sie enthaltende arzneimittel |
-
1986
- 1986-08-01 AR AR86305006A patent/AR243167A1/es active
- 1986-08-12 DE DE8686111104T patent/DE3687675D1/de not_active Expired - Fee Related
- 1986-08-12 AT AT86111104T patent/ATE85328T1/de not_active IP Right Cessation
- 1986-08-12 EP EP86111104A patent/EP0213474B1/de not_active Expired - Lifetime
- 1986-08-21 FI FI863382A patent/FI89910C/fi not_active IP Right Cessation
- 1986-08-22 DK DK401586A patent/DK401586A/da not_active Application Discontinuation
- 1986-08-22 IL IL79813A patent/IL79813A0/xx unknown
- 1986-08-22 GR GR862180A patent/GR862180B/el unknown
- 1986-08-22 NO NO863389A patent/NO169169C/no unknown
- 1986-08-22 NZ NZ217322A patent/NZ217322A/xx unknown
- 1986-08-22 HU HU863659A patent/HU199126B/hu not_active IP Right Cessation
- 1986-08-22 PT PT83240A patent/PT83240B/pt not_active IP Right Cessation
- 1986-08-22 PH PH34172A patent/PH24073A/en unknown
- 1986-08-22 KR KR1019860006949A patent/KR940005020B1/ko not_active IP Right Cessation
- 1986-08-22 ES ES8601270A patent/ES2001389A6/es not_active Expired
- 1986-08-22 JP JP61195738A patent/JPH0791276B2/ja not_active Expired - Lifetime
- 1986-08-22 IE IE225886A patent/IE59587B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NZ217322A (en) | 1990-02-26 |
ATE85328T1 (de) | 1993-02-15 |
HU199126B (en) | 1990-01-29 |
NO169169C (no) | 1992-05-20 |
HUT44242A (en) | 1988-02-29 |
IL79813A0 (en) | 1986-11-30 |
NO169169B (no) | 1992-02-10 |
DE3687675D1 (de) | 1993-03-18 |
IE59587B1 (en) | 1994-03-09 |
GR862180B (en) | 1986-12-23 |
NO863389D0 (no) | 1986-08-22 |
FI89910B (fi) | 1993-08-31 |
DK401586A (da) | 1987-02-25 |
JPS6251671A (ja) | 1987-03-06 |
NO863389L (no) | 1987-02-25 |
FI89910C (fi) | 1993-12-10 |
EP0213474A2 (de) | 1987-03-11 |
JPH0791276B2 (ja) | 1995-10-04 |
PT83240A (de) | 1986-09-01 |
EP0213474A3 (en) | 1987-05-20 |
DK401586D0 (da) | 1986-08-22 |
FI863382A (fi) | 1987-02-25 |
ES2001389A6 (es) | 1988-05-16 |
EP0213474B1 (de) | 1993-02-03 |
AU595231B2 (en) | 1990-03-29 |
KR870002087A (ko) | 1987-03-30 |
FI863382A0 (fi) | 1986-08-21 |
PT83240B (pt) | 1989-03-30 |
AR243167A1 (es) | 1993-07-30 |
KR940005020B1 (ko) | 1994-06-09 |
AU6174586A (en) | 1987-02-26 |
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