FI863382A - Substituerade toluidiner, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska produkter och deras anvaendning foer haemmande av magsyrasekretion. - Google Patents

Substituerade toluidiner, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska produkter och deras anvaendning foer haemmande av magsyrasekretion. Download PDF

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Publication number
FI863382A
FI863382A FI863382A FI863382A FI863382A FI 863382 A FI863382 A FI 863382A FI 863382 A FI863382 A FI 863382A FI 863382 A FI863382 A FI 863382A FI 863382 A FI863382 A FI 863382A
Authority
FI
Finland
Prior art keywords
foer
deras
toluidiner
magsyrasekretion
haemmande
Prior art date
Application number
FI863382A
Other languages
English (en)
Other versions
FI863382A0 (fi
FI89910C (fi
FI89910B (fi
Inventor
Hans-Jochen Lang
Gerhard Rackur
Manfred Roesner
Andreas W Herling
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19853530342 external-priority patent/DE3530342A1/de
Priority claimed from DE19863610609 external-priority patent/DE3610609A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI863382A0 publication Critical patent/FI863382A0/fi
Publication of FI863382A publication Critical patent/FI863382A/fi
Application granted granted Critical
Publication of FI89910B publication Critical patent/FI89910B/fi
Publication of FI89910C publication Critical patent/FI89910C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI863382A 1985-08-24 1986-08-21 Foerfarande foer framstaellning av terapeutiskt aktiva bensimidazolderivat FI89910C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3530342 1985-08-24
DE19853530342 DE3530342A1 (de) 1985-08-24 1985-08-24 Substituierte toluidine, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
DE19863610609 DE3610609A1 (de) 1986-03-29 1986-03-29 Substituierte toluidine, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
DE3610609 1986-03-29

Publications (4)

Publication Number Publication Date
FI863382A0 FI863382A0 (fi) 1986-08-21
FI863382A true FI863382A (fi) 1987-02-25
FI89910B FI89910B (fi) 1993-08-31
FI89910C FI89910C (fi) 1993-12-10

Family

ID=25835350

Family Applications (1)

Application Number Title Priority Date Filing Date
FI863382A FI89910C (fi) 1985-08-24 1986-08-21 Foerfarande foer framstaellning av terapeutiskt aktiva bensimidazolderivat

Country Status (17)

Country Link
EP (1) EP0213474B1 (fi)
JP (1) JPH0791276B2 (fi)
KR (1) KR940005020B1 (fi)
AR (1) AR243167A1 (fi)
AT (1) ATE85328T1 (fi)
DE (1) DE3687675D1 (fi)
DK (1) DK401586A (fi)
ES (1) ES2001389A6 (fi)
FI (1) FI89910C (fi)
GR (1) GR862180B (fi)
HU (1) HU199126B (fi)
IE (1) IE59587B1 (fi)
IL (1) IL79813A0 (fi)
NO (1) NO169169C (fi)
NZ (1) NZ217322A (fi)
PH (1) PH24073A (fi)
PT (1) PT83240B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3773240D1 (de) 1986-03-28 1991-10-31 Otsuka Pharma Co Ltd Hydrochinolinverbindungen, diese enthaltende zusammensetzungen und verfahren zu ihrer herstellung.
EP0251536A1 (en) * 1986-06-24 1988-01-07 FISONS plc Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
US4957932A (en) * 1987-11-25 1990-09-18 Merck Frosst Canada, Inc. Benzoheterazoles
EP0318085A3 (en) * 1987-11-25 1990-03-14 Merck Frosst Canada Inc. Heterazole dialkanoic acids
JP2564162B2 (ja) * 1988-02-12 1996-12-18 日本ケミファ株式会社 ベンズイミダゾール誘導体の四級塩
ES2047451B1 (es) * 1992-07-10 1994-10-01 Sint Quimica Sa Procedimiento para la preparacion de una composicion farmaceutica oral estable.
KR20040028815A (ko) * 2004-01-07 2004-04-03 화인고무(주) 접착제를 사용하지 않는 사출 및 열융착을 가능하게하는인조피혁
CN115433167B (zh) * 2022-11-10 2023-03-24 中国药科大学 具有Snail抑制活性的苯并杂环类化合物、其制备方法、药物组合物和医药用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE332167C (de) 1918-08-09 1921-01-26 Chem Fab Vorm Goldenberg Glyzerinersatz
BE788805A (fr) 1971-09-22 1973-01-02 Lafon Victor Nouveaux derives antalgiques de la serie des arylamines soufrees
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
US4472409A (en) 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
DE3333314A1 (de) 1983-09-15 1985-03-28 Hoechst Ag, 6230 Frankfurt Substituierte pyrido(1,2-c)imidazo(1,2-a)benzimidazole, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
GB8417271D0 (en) * 1984-07-06 1984-08-08 Fisons Plc Biologically active nitrogen heterocycles
EP0174717B1 (en) 1984-07-06 1992-01-22 FISONS plc Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors
AU4640985A (en) 1984-08-31 1986-03-06 Nippon Chemiphar Co. Ltd. Benzimidazole derivatives
DE3509333A1 (de) 1985-03-15 1986-09-18 Hoechst Ag, 6230 Frankfurt Substituierte benzimidazolderivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
EP0204215B1 (en) * 1985-05-24 1993-08-11 G.D. Searle & Co. 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-benzenamines
EP0232399A1 (de) * 1985-08-21 1987-08-19 Byk Gulden Lomberg Chemische Fabrik GmbH Neue amine, verfahren zu ihrer herstellung, ihre anwendung und sie enthaltende arzneimittel

Also Published As

Publication number Publication date
FI863382A0 (fi) 1986-08-21
IE59587B1 (en) 1994-03-09
DK401586D0 (da) 1986-08-22
HU199126B (en) 1990-01-29
ES2001389A6 (es) 1988-05-16
AU6174586A (en) 1987-02-26
IL79813A0 (en) 1986-11-30
DE3687675D1 (de) 1993-03-18
EP0213474B1 (de) 1993-02-03
PT83240A (de) 1986-09-01
AU595231B2 (en) 1990-03-29
DK401586A (da) 1987-02-25
GR862180B (en) 1986-12-23
NO169169C (no) 1992-05-20
KR870002087A (ko) 1987-03-30
HUT44242A (en) 1988-02-29
FI89910C (fi) 1993-12-10
PH24073A (en) 1990-03-05
NZ217322A (en) 1990-02-26
PT83240B (pt) 1989-03-30
EP0213474A2 (de) 1987-03-11
NO169169B (no) 1992-02-10
AR243167A1 (es) 1993-07-30
ATE85328T1 (de) 1993-02-15
JPS6251671A (ja) 1987-03-06
NO863389D0 (no) 1986-08-22
JPH0791276B2 (ja) 1995-10-04
KR940005020B1 (ko) 1994-06-09
FI89910B (fi) 1993-08-31
EP0213474A3 (en) 1987-05-20
NO863389L (no) 1987-02-25

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Owner name: HOECHST AKTIENGESELLSCHAFT