PH14298A - 5-or 6-pyridazinyl-benimidazoles and salts thereof - Google Patents

5-or 6-pyridazinyl-benimidazoles and salts thereof

Info

Publication number
PH14298A
PH14298A PH17237A PH17237A PH14298A PH 14298 A PH14298 A PH 14298A PH 17237 A PH17237 A PH 17237A PH 17237 A PH17237 A PH 17237A PH 14298 A PH14298 A PH 14298A
Authority
PH
Philippines
Prior art keywords
benimidazoles
pyridazinyl
salts
Prior art date
Application number
PH17237A
Other languages
English (en)
Inventor
J Heider
V Austel
R Kadatz
E Kutter
W Eberlein
W Diederen
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742427943 external-priority patent/DE2427943C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of PH14298A publication Critical patent/PH14298A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH17237A 1974-06-10 1975-06-05 5-or 6-pyridazinyl-benimidazoles and salts thereof PH14298A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742427943 DE2427943C2 (de) 1974-06-10 1974-06-10 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2516040A DE2516040C2 (de) 1974-06-10 1975-04-12 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
PH14298A true PH14298A (en) 1981-05-19

Family

ID=25767253

Family Applications (1)

Application Number Title Priority Date Filing Date
PH17237A PH14298A (en) 1974-06-10 1975-06-05 5-or 6-pyridazinyl-benimidazoles and salts thereof

Country Status (23)

Country Link
US (1) US4026891A (no)
JP (1) JPS6015632B2 (no)
AT (1) AT342610B (no)
BE (1) BE830030A (no)
BG (2) BG23216A3 (no)
CA (1) CA1041095A (no)
CH (1) CH620438A5 (no)
CS (1) CS195292B2 (no)
DD (1) DD120440A5 (no)
DE (1) DE2516040C2 (no)
DK (1) DK258975A (no)
ES (2) ES437296A1 (no)
FI (1) FI59408C (no)
FR (1) FR2273545A1 (no)
GB (1) GB1466547A (no)
HU (1) HU171059B (no)
IE (1) IE41257B1 (no)
IL (1) IL47445A (no)
NL (1) NL178969C (no)
NO (1) NO142402C (no)
PH (1) PH14298A (no)
RO (1) RO68750A (no)
SE (1) SE420836B (no)

Families Citing this family (42)

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JPS53117215A (en) * 1977-03-24 1978-10-13 Hideyoshi Morita Earthquakeeproof steel beam
ES8101067A1 (es) * 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
DE2935359A1 (de) * 1979-09-01 1981-03-26 Basf Ag, 67063 Ludwigshafen 6-imidazolyl-3-hydrazino-pyridazine
DE3006671A1 (de) * 1980-02-22 1981-08-27 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzoxazole, deren herstellung und deren verwendung als arzneumittel
DE3129447A1 (de) * 1981-07-25 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benztriazole, ihre herstellung und ihre verwendung als arzneimittel"
US4699909A (en) * 1981-07-25 1987-10-13 Dr. Karl Thomae Gmbh Benzotriazolyl-4,5-dihydro-3(2H)-pyridazinones
US4840955A (en) * 1984-12-24 1989-06-20 Warner-Lambert Company 6-substituted-2(1H)-quinolinones and related compounds having use as cardiotonic, antihypertensive, and antithrombotic agents
ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
US4906630A (en) * 1985-11-22 1990-03-06 Rorer Pharmaceutical Corporation Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds
US4725686A (en) * 1985-11-22 1988-02-16 William H. Rorer, Inc. Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4785101A (en) * 1985-11-22 1988-11-15 Rorer Pharmaceutical Corporation Benzodiazinone-hydroxypyrazolyl compounds, cardiotonic compositions including the same and their uses
US4868300A (en) * 1985-11-22 1989-09-19 Rorer Pharmaceutical Corporation Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
JPS62249019A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
JPS62249018A (ja) * 1986-04-21 1987-10-30 Anritsu Corp 組合せ計量装置
US5002944A (en) * 1986-10-29 1991-03-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having cardiotonic activity
US4859672A (en) * 1986-10-29 1989-08-22 Rorer Pharmaceutical Corporation Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone
JPS63181827U (no) * 1987-05-13 1988-11-24
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate
US6162804A (en) * 1997-09-26 2000-12-19 Merck & Co., Inc. Tyrosine kinase inhibitors
US6465484B1 (en) 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
EP1123703B1 (en) * 1998-10-23 2004-04-14 Toray Industries, Inc. Immunomodulatory drug composition
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines
CN101084207A (zh) * 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途
AR051092A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa
CN101084212A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶介导剂的用途
BRPI0515483A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos para o tratamento de doenças mediadas por enzimas estearoil-coa desaturase
US7829712B2 (en) 2004-09-20 2010-11-09 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase
CN101083993A (zh) * 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途
AR051294A1 (es) * 2004-09-20 2007-01-03 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
AR051090A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
JP4714921B2 (ja) * 2005-02-14 2011-07-06 トーアエイヨー株式会社 ピモベンダンの製造法及びその中間体
US8541457B2 (en) * 2005-06-03 2013-09-24 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
CN103110635A (zh) 2005-07-04 2013-05-22 海波因特制药有限责任公司 组胺h3受体拮抗剂
RU2385865C2 (ru) * 2005-08-15 2010-04-10 Айрм Ллк Соединения и композиции в качестве миметиков тро
EA016026B1 (ru) * 2006-05-29 2012-01-30 ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи 3-(1,3-бензодиоксол-5-ил)-6-(4-циклопропилпиперазин-1-ил)пиридазин, его соли и сольваты и его применение в качестве антагониста н3 рецептора гистамина
EP2014656A3 (en) * 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC New heteocyclic h3 antagonists
US8637507B2 (en) * 2009-03-18 2014-01-28 Merck Sharp & Dohme Corp. Bicyclic compounds as inhibitors of diacylglycerol acyltransferase
US8729263B2 (en) 2012-08-13 2014-05-20 Novartis Ag 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions
CN105636953B (zh) * 2013-07-31 2018-01-02 诺华股份有限公司 1,4‑二取代的哒嗪衍生物及其用于治疗与smn缺乏相关的病症的用途
WO2018086703A1 (en) * 2016-11-11 2018-05-17 Bayer Pharma Aktiengesellschaft Dihydropyridazinones substituted with phenylureas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
US3705157A (en) * 1970-10-19 1972-12-05 American Cyanamid Co Azolylpyridazine compounds and quaternary salts thereof
US3935209A (en) * 1973-03-12 1976-01-27 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles

Also Published As

Publication number Publication date
NO142402B (no) 1980-05-05
DE2516040A1 (de) 1976-11-04
IE41257L (en) 1975-12-10
CA1041095A (en) 1978-10-24
FI59408C (fi) 1981-08-10
BG23216A3 (no) 1977-07-12
HU171059B (hu) 1977-10-28
NO752022L (no) 1975-12-11
BE830030A (fr) 1975-12-09
NL7506806A (nl) 1975-12-12
FI751700A (no) 1975-12-11
DD120440A5 (no) 1976-06-12
SE7506583L (sv) 1975-12-11
BG24052A3 (en) 1977-12-15
AT342610B (de) 1978-04-10
US4026891A (en) 1977-05-31
CH620438A5 (no) 1980-11-28
NL178969C (nl) 1986-06-16
GB1466547A (en) 1977-03-09
NO142402C (no) 1980-08-13
DK258975A (da) 1975-12-11
ATA344575A (de) 1977-08-15
CS195292B2 (en) 1980-01-31
FI59408B (fi) 1981-04-30
DE2516040C2 (de) 1984-12-20
AU8192675A (en) 1976-12-16
FR2273545B1 (no) 1979-08-10
ES441340A1 (es) 1977-03-16
FR2273545A1 (fr) 1976-01-02
SE420836B (sv) 1981-11-02
RO68750A (ro) 1980-03-15
ES437296A1 (es) 1977-01-01
JPS6015632B2 (ja) 1985-04-20
IL47445A (en) 1978-07-31
JPS516980A (no) 1976-01-20
IL47445A0 (en) 1975-08-31
IE41257B1 (en) 1979-11-21

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