PE43697A1 - Nueva clase de sulfonamidas, inhibidoras de la proteasa aspartilo - Google Patents
Nueva clase de sulfonamidas, inhibidoras de la proteasa aspartiloInfo
- Publication number
- PE43697A1 PE43697A1 PE1996000266A PE00026696A PE43697A1 PE 43697 A1 PE43697 A1 PE 43697A1 PE 1996000266 A PE1996000266 A PE 1996000266A PE 00026696 A PE00026696 A PE 00026696A PE 43697 A1 PE43697 A1 PE 43697A1
- Authority
- PE
- Peru
- Prior art keywords
- het
- fused
- optionally
- protease inhibitors
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
- C07D317/36—Alkylene carbonates; Substituted alkylene carbonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
Abstract
SE REFIERE A COMPUESTOS DE FORMULA (I), DONDE: R1 ES -C(O)- O O-C(O)-, ENTRE OTROS; A ES UN HETEROCICLO NO AROMATICO DE 5, 6 O 7 MIEMBROS, CON 1, 2 O 3 OXIGENOS ENDOGENOS, OPCIONALMENTE (BENZOFUSIONADO, ENLAZADO POR UN ALQUIL C1-C3 Y/O FUSIONADO CON UN HETEROCICLO NO AROMATICO DE 5, 6 O 7 MIEMBROS, CON 1 O 2 HETEROATOMOS, PERO NO ES TETRAHIDROFURANO, NI TETRAHIDROFUROTETRAHIDROFURANO; D Y D` SON INDEPENDIENTEMENTE R6, [ALQUILO C1-C5 O ALQUENILO C2-C4 OPCIONALMENTE SUSTITUIDO CON R6, ENTRE OTROS] O ES CARBOCICLO C3-C6, QUE PUEDE ESTAR OPCIONALMENTE SUSTITUIDO CON O FUSIONADO CON R6; R6 ES ARILO, CARBOCICLO O HETEROCICLO OPCIONALMENTE SUSTITUIDO CON OXO, ENTRE OTROS; E ES HET, O-HET O HET-HET, ENTRE OTROS, SIENDO PREFERENTEMENTE FENILO OPCIONALMENTE SUSTITUIDO CON OH, OCH3 O NH2, ENTRE OTROS O FENILO FUSIONADO CON UN HETEROCICLO O CARBOCICLO DE 5 O 6 MIEMBROS; HET ES CARBOCICLO C3-C7 O ARILO C6-C10, ENTRE OTROS. TAMBIEN SE REFIERE AL METODO PARA TRATAR LA INFECCION HIV , QUE COMPRENDE ADMINISTRAR EL COMPUESTO I (QUE ES INHIBIDOR DE LA PROTEASA ASPARTILO DEL HIV), CON UN AGENTE ADICIONAL ANTIVIRAL E INMUNOESTIMULADOR COMO SON LOS INHIBIDORES DE PROTEASA O INHIBIDORES DE TRANSCRIPTASA INVERSA, QUE PUEDE SER ANALOGOS NUCLEOSICOS (AZT O DIDESOXICITIDINA, ENTRE OTROS) O NO NUCLEOSICOS (DELAVIRDINA, ENTRE OTROS)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/424,810 US5691372A (en) | 1995-04-19 | 1995-04-19 | Oxygenated-Heterocycle containing sulfonamide inhibitors of aspartyl protease |
Publications (1)
Publication Number | Publication Date |
---|---|
PE43697A1 true PE43697A1 (es) | 1997-10-11 |
Family
ID=23683966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1996000266A PE43697A1 (es) | 1995-04-19 | 1996-04-18 | Nueva clase de sulfonamidas, inhibidoras de la proteasa aspartilo |
Country Status (35)
Country | Link |
---|---|
US (2) | US5691372A (es) |
EP (3) | EP1136479B1 (es) |
JP (1) | JP4240532B2 (es) |
KR (1) | KR100485237B1 (es) |
CN (1) | CN1110491C (es) |
AP (2) | AP9600827A0 (es) |
AR (1) | AR004663A1 (es) |
AT (3) | ATE314360T1 (es) |
AU (1) | AU712913B2 (es) |
BG (1) | BG102041A (es) |
BR (1) | BR9608033A (es) |
CA (1) | CA2217745C (es) |
CO (1) | CO4700433A1 (es) |
CZ (1) | CZ329497A3 (es) |
DE (3) | DE69638252D1 (es) |
DK (1) | DK0833826T3 (es) |
EA (1) | EA000906B1 (es) |
EE (1) | EE9700254A (es) |
ES (3) | ES2256117T3 (es) |
GE (1) | GEP20001915B (es) |
HK (2) | HK1009811A1 (es) |
HU (1) | HUP9801948A3 (es) |
IL (1) | IL117962A0 (es) |
IS (1) | IS4575A (es) |
MY (1) | MY115797A (es) |
NO (1) | NO974744L (es) |
NZ (1) | NZ307342A (es) |
PE (1) | PE43697A1 (es) |
PL (1) | PL322904A1 (es) |
PT (1) | PT833826E (es) |
SK (1) | SK143097A3 (es) |
TR (1) | TR199701194T1 (es) |
TW (1) | TW404945B (es) |
WO (1) | WO1996033187A1 (es) |
ZA (1) | ZA962891B (es) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040122000A1 (en) | 1981-01-07 | 2004-06-24 | Vertex Pharmaceuticals Incorporated. | Inhibitors of aspartyl protease |
US5843946A (en) | 1992-08-25 | 1998-12-01 | G.D. Searle & Co. | α-and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors |
US7141609B2 (en) | 1992-08-25 | 2006-11-28 | G.D. Searle & Co. | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors |
US5942253A (en) | 1995-10-12 | 1999-08-24 | Immunex Corporation | Prolonged release of GM-CSF |
EA002593B1 (ru) | 1996-12-31 | 2002-06-27 | Гилфорд Фармасьютикалз Инк. | N-связанные сульфонамиды гетероциклических тиоэфиров |
US5874449A (en) * | 1996-12-31 | 1999-02-23 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of heterocyclic thioesters |
BR9809124A (pt) * | 1997-05-17 | 2000-08-01 | Glaxo Group Ltd | Combinação, formulação, farmacêutica, processo para o tratamento de uma infecção por hiv em um animal, infectado, uso de (-)-(1s, 4r)-4-[2-amino-6-(ciclopropilamino)-9h-purin-9-il)-2-cicl openteno-1-metanol, e, pacote de paciente |
US5945441A (en) | 1997-06-04 | 1999-08-31 | Gpi Nil Holdings, Inc. | Pyrrolidine carboxylate hair revitalizing agents |
US6576231B2 (en) * | 1997-09-12 | 2003-06-10 | Schering Ag | Methods for treating HIV-Infected Patients by the Administration of GM-CSF and a protease inhibitor |
EP1042280A2 (en) * | 1997-12-24 | 2000-10-11 | Vertex Pharmaceuticals Incorporated | Prodrugs of aspartyl protease inhibitors |
US6436989B1 (en) | 1997-12-24 | 2002-08-20 | Vertex Pharmaceuticals, Incorporated | Prodrugs of aspartyl protease inhibitors |
WO1999065870A2 (en) * | 1998-06-19 | 1999-12-23 | Vertex Pharmaceuticals Incorporated | Sulfonamide inhibitors of aspartyl protease |
AU771780B2 (en) * | 1998-06-23 | 2004-04-01 | Board Of Trustees Of The University Of Illinois, The | Fitness assay and associated methods |
US6339101B1 (en) | 1998-08-14 | 2002-01-15 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders |
US6376517B1 (en) | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
US6218423B1 (en) | 1998-08-14 | 2001-04-17 | Gpi Nil Holdings, Inc. | Pyrrolidine derivatives for vision and memory disorders |
US6337340B1 (en) | 1998-08-14 | 2002-01-08 | Gpi Nil Holdings, Inc. | Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders |
US6399648B1 (en) | 1998-08-14 | 2002-06-04 | Gpi Nil Holdings, Inc. | N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders |
US6395758B1 (en) | 1998-08-14 | 2002-05-28 | Gpi Nil Holdings, Inc. | Small molecule carbamates or ureas for vision and memory disorders |
US6462072B1 (en) | 1998-09-21 | 2002-10-08 | Gpi Nil Holdings, Inc. | Cyclic ester or amide derivatives |
TWI260322B (en) | 1999-02-12 | 2006-08-21 | Vertex Pharma | Inhibitors of aspartyl protease |
AU3485800A (en) * | 1999-02-12 | 2000-08-29 | Vertex Pharmaceuticals Incorporated | Inhibitors of aspartyl protease |
AR031520A1 (es) * | 1999-06-11 | 2003-09-24 | Vertex Pharma | Un compuesto inhibidor de aspartilo proteasa, una composicion que lo comprende y un metodo para tratar un paciente con dicha composicion |
CZ300031B6 (cs) * | 1999-10-06 | 2009-01-14 | Tibotec Pharmaceuticals Ltd. | Hexahydrofuro[2,3-b]furan-3-yl-N-{3-[(1,3-benzodioxol-5-ylsulfonyl) (isobutyl)amino]-1-benzyl-2-hydroxypropyl}karbamát a farmaceutický prípravek s jeho obsahem |
IL151475A0 (en) | 2000-03-30 | 2003-04-10 | Bristol Myers Squibb Co | Beadlets containing stavudine |
AP1544A (en) * | 2001-04-09 | 2006-01-12 | Tibotec Pharm Ltd | Broadspectrum 2- (substituted-amino) -benzoxazole sulfonamide HIV protease inhibitors. |
US7109230B2 (en) * | 2002-01-07 | 2006-09-19 | Sequoia Pharmaceuticals, Inc. | Resistance-repellent retroviral protease inhibitors |
US7157489B2 (en) * | 2002-03-12 | 2007-01-02 | The Board Of Trustees Of The University Of Illinois | HIV protease inhibitors |
WO2004033152A1 (en) * | 2002-10-11 | 2004-04-22 | Semplastics, L.L.C. | Retaining ring for use on a carrier of a polishing apparatus |
WO2004050609A1 (en) * | 2002-11-27 | 2004-06-17 | Elan Pharmaceutical, Inc. | Substituted ureas and carbamates |
US20050131042A1 (en) * | 2003-12-11 | 2005-06-16 | Flentge Charles A. | HIV protease inhibiting compounds |
US7763609B2 (en) * | 2003-12-15 | 2010-07-27 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
WO2006104646A1 (en) * | 2005-03-11 | 2006-10-05 | Smithkline Beecham Corporation | Hiv protease inhibitors |
JP2007202679A (ja) * | 2006-01-31 | 2007-08-16 | Juki Corp | ミシンの糸調子装置 |
JP2007202833A (ja) * | 2006-02-02 | 2007-08-16 | Juki Corp | ミシンの糸調子装置 |
EP2120562A4 (en) * | 2006-11-21 | 2010-01-13 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR TREATING HIV INFECTIONS |
EP2244571A4 (en) | 2008-01-17 | 2014-02-19 | Purdue Research Foundation | SMALL INHIBITORY MOLECULES OF HIV PROTEASES |
WO2010002994A1 (en) | 2008-07-01 | 2010-01-07 | Purdue Research Foundation | Nonpeptide hiv-1 protease inhibitors |
EP2304043A4 (en) | 2008-07-09 | 2012-05-30 | Purdue Research Foundation | HIV PROTEASE INHIBITORS AND METHOD FOR THEIR USE |
CN105272991B (zh) * | 2014-06-26 | 2017-11-07 | 成都中医药大学 | 一种化合物晶型 |
US11090030B2 (en) | 2016-11-10 | 2021-08-17 | Leltek Inc. | Ultrasound apparatus and ultrasound emission method |
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FR2459235A1 (fr) * | 1979-06-14 | 1981-01-09 | Sanofi Sa | Nouveaux derives de sulfonyl-aniline, leur procede de preparation et leur application therapeutique |
JPS5946252A (ja) * | 1982-09-09 | 1984-03-15 | Dainippon Ink & Chem Inc | 含フツ素アミノカルボキシレ−トおよびその製法 |
JPS5948449A (ja) * | 1982-09-13 | 1984-03-19 | Dainippon Ink & Chem Inc | 直鎖状含フツ素アニオン化合物およびその製造方法 |
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EP0541168B1 (en) * | 1991-11-08 | 1998-03-11 | Merck & Co. Inc. | HIV protease inhibitors useful for the treatment of aids |
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CA2142998C (en) * | 1992-08-25 | 2008-01-29 | Michael L. Vazquez | N-(alkanoylamino-2-hydroxypropyl)-sulfonamides useful as retroviral protease inhibitors |
US5843946A (en) * | 1992-08-25 | 1998-12-01 | G.D. Searle & Co. | α-and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors |
JP4091654B2 (ja) * | 1992-08-25 | 2008-05-28 | ジー.ディー.サール、リミテッド、ライアビリティ、カンパニー | レトロウイルスプロテアーゼ阻害剤として有用なスルホニルアルカノイルアミノヒドロキシエチルアミノスルホンアミド |
US5723490A (en) * | 1992-09-08 | 1998-03-03 | Vertex Pharmaceuticals Incorporated | THF-containing sulfonamide inhibitors of aspartyl protease |
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-
1995
- 1995-04-19 US US08/424,810 patent/US5691372A/en not_active Expired - Lifetime
-
1996
- 1996-04-11 TW TW085104278A patent/TW404945B/zh not_active IP Right Cessation
- 1996-04-11 ZA ZA962891A patent/ZA962891B/xx unknown
- 1996-04-17 AR ARP960102210A patent/AR004663A1/es unknown
- 1996-04-17 AP APAP/P/1996/000827A patent/AP9600827A0/en unknown
- 1996-04-18 GE GEAP19963972A patent/GEP20001915B/en unknown
- 1996-04-18 HU HU9801948A patent/HUP9801948A3/hu unknown
- 1996-04-18 KR KR1019970707346A patent/KR100485237B1/ko not_active IP Right Cessation
- 1996-04-18 EA EA199700330A patent/EA000906B1/ru not_active IP Right Cessation
- 1996-04-18 AU AU56655/96A patent/AU712913B2/en not_active Expired
- 1996-04-18 BR BR9608033A patent/BR9608033A/pt not_active Application Discontinuation
- 1996-04-18 PL PL96322904A patent/PL322904A1/xx unknown
- 1996-04-18 TR TR97/01194T patent/TR199701194T1/xx unknown
- 1996-04-18 ES ES01113575T patent/ES2256117T3/es not_active Expired - Lifetime
- 1996-04-18 ES ES05028389T patent/ES2351970T3/es not_active Expired - Lifetime
- 1996-04-18 EP EP01113575A patent/EP1136479B1/en not_active Expired - Lifetime
- 1996-04-18 EE EE9700254A patent/EE9700254A/xx unknown
- 1996-04-18 CZ CZ973294A patent/CZ329497A3/cs unknown
- 1996-04-18 AT AT01113575T patent/ATE314360T1/de active
- 1996-04-18 AT AT96913811T patent/ATE212344T1/de active
- 1996-04-18 CA CA2217745A patent/CA2217745C/en not_active Expired - Lifetime
- 1996-04-18 PE PE1996000266A patent/PE43697A1/es not_active Application Discontinuation
- 1996-04-18 JP JP53195396A patent/JP4240532B2/ja not_active Expired - Lifetime
- 1996-04-18 CN CN96193903A patent/CN1110491C/zh not_active Expired - Fee Related
- 1996-04-18 ES ES96913811T patent/ES2171670T3/es not_active Expired - Lifetime
- 1996-04-18 SK SK1430-97A patent/SK143097A3/sk unknown
- 1996-04-18 AT AT05028389T patent/ATE479674T1/de not_active IP Right Cessation
- 1996-04-18 DE DE69638252T patent/DE69638252D1/de not_active Expired - Lifetime
- 1996-04-18 MY MYPI96001465A patent/MY115797A/en unknown
- 1996-04-18 AP APAP/P/1997/001104A patent/AP862A/en active
- 1996-04-18 WO PCT/US1996/005473 patent/WO1996033187A1/en active IP Right Grant
- 1996-04-18 DE DE69618779T patent/DE69618779T2/de not_active Expired - Lifetime
- 1996-04-18 PT PT96913811T patent/PT833826E/pt unknown
- 1996-04-18 DE DE69635679T patent/DE69635679T2/de not_active Expired - Lifetime
- 1996-04-18 EP EP05028389A patent/EP1637528B1/en not_active Expired - Lifetime
- 1996-04-18 IL IL11796296A patent/IL117962A0/xx unknown
- 1996-04-18 EP EP96913811A patent/EP0833826B1/en not_active Expired - Lifetime
- 1996-04-18 DK DK96913811T patent/DK0833826T3/da active
- 1996-04-19 CO CO96019067A patent/CO4700433A1/es unknown
-
1997
- 1997-10-02 IS IS4575A patent/IS4575A/is unknown
- 1997-10-08 NZ NZ307342A patent/NZ307342A/en unknown
- 1997-10-14 NO NO974744A patent/NO974744L/no not_active Application Discontinuation
- 1997-11-13 BG BG102041A patent/BG102041A/xx unknown
- 1997-11-24 US US08/977,365 patent/US5990155A/en not_active Expired - Lifetime
-
1998
- 1998-09-22 HK HK98110833A patent/HK1009811A1/xx not_active IP Right Cessation
- 1998-09-22 HK HK06110563.0A patent/HK1092791A1/xx not_active IP Right Cessation
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