PE20191615A1 - Compuestos quimicos como inhibidores de la actividad de la interleuquina-1 - Google Patents

Compuestos quimicos como inhibidores de la actividad de la interleuquina-1

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Publication number
PE20191615A1
PE20191615A1 PE2019001474A PE2019001474A PE20191615A1 PE 20191615 A1 PE20191615 A1 PE 20191615A1 PE 2019001474 A PE2019001474 A PE 2019001474A PE 2019001474 A PE2019001474 A PE 2019001474A PE 20191615 A1 PE20191615 A1 PE 20191615A1
Authority
PE
Peru
Prior art keywords
compounds
formulas
inhibitors
interleuquin
activity
Prior art date
Application number
PE2019001474A
Other languages
English (en)
Spanish (es)
Inventor
Jeffrey A Stafford
James M Veal
Lynnie Lin Trzoss
Christopher Mcbride
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PE20191615A1 publication Critical patent/PE20191615A1/es

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    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
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    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/4161,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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PE2019001474A 2017-01-23 2018-01-22 Compuestos quimicos como inhibidores de la actividad de la interleuquina-1 PE20191615A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762449431P 2017-01-23 2017-01-23
US201762492813P 2017-05-01 2017-05-01
PCT/US2018/014728 WO2018136890A1 (en) 2017-01-23 2018-01-22 Chemical compounds as inhibitors of interleukin-1 activity

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