CL2022001741A1 - Compuestos cíclicos y métodos de uso de estos - Google Patents

Compuestos cíclicos y métodos de uso de estos

Info

Publication number
CL2022001741A1
CL2022001741A1 CL2022001741A CL2022001741A CL2022001741A1 CL 2022001741 A1 CL2022001741 A1 CL 2022001741A1 CL 2022001741 A CL2022001741 A CL 2022001741A CL 2022001741 A CL2022001741 A CL 2022001741A CL 2022001741 A1 CL2022001741 A1 CL 2022001741A1
Authority
CL
Chile
Prior art keywords
methods
same
cyclic compounds
compounds
cancer
Prior art date
Application number
CL2022001741A
Other languages
English (en)
Inventor
FENG Shulu
LAWRENZ Morgan
Krilov Goran
Placzek Andrew
Nie Zhe
TRZOSS Lynnie
Trzoss Michael
Tang Haifeng
Rachel Lagiakos H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of CL2022001741A1 publication Critical patent/CL2022001741A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La presente solicitud también describe una composición farmacéutica que comprende un compuesto de la Fórmula (I), y sales aceptables desde el punto de vista farmacéuticode este, y métodos para usar los compuestos y las composiciones para tratar enfermedades, tales como cáncer, trastornos autoinmunitarios y trastornos inflamatorios.
CL2022001741A 2019-12-27 2022-06-24 Compuestos cíclicos y métodos de uso de estos CL2022001741A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962954262P 2019-12-27 2019-12-27
US202063040582P 2020-06-18 2020-06-18
US202063119521P 2020-11-30 2020-11-30

Publications (1)

Publication Number Publication Date
CL2022001741A1 true CL2022001741A1 (es) 2023-01-27

Family

ID=74206185

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2022001741A CL2022001741A1 (es) 2019-12-27 2022-06-24 Compuestos cíclicos y métodos de uso de estos

Country Status (13)

Country Link
US (1) US20240018157A1 (es)
EP (1) EP4081526A1 (es)
JP (2) JP2023509886A (es)
KR (1) KR20220123023A (es)
CN (1) CN114945571A (es)
AU (1) AU2020413333A1 (es)
BR (1) BR112022012684A2 (es)
CA (1) CA3161339A1 (es)
CL (1) CL2022001741A1 (es)
IL (1) IL294214A (es)
MX (1) MX2022007171A (es)
TW (1) TW202136270A (es)
WO (1) WO2021134004A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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TW202320755A (zh) * 2021-09-30 2023-06-01 大陸商上海拓界生物醫藥科技有限公司 三環化合物及其製備方法
TW202342032A (zh) 2022-02-02 2023-11-01 日商小野藥品工業股份有限公司 含有ｍａｌｔ１抑制劑作為有效成分的癌治療劑
TW202417445A (zh) * 2022-07-22 2024-05-01 美商薛定諤公司 環狀化合物及其使用方法
WO2024133859A1 (en) * 2022-12-23 2024-06-27 Janssen Pharmaceutica Nv Malt1 inhibitors

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Also Published As

Publication number Publication date
JP2023509886A (ja) 2023-03-10
CA3161339A1 (en) 2021-07-01
AU2020413333A1 (en) 2022-06-16
KR20220123023A (ko) 2022-09-05
MX2022007171A (es) 2022-08-22
JP2024023699A (ja) 2024-02-21
WO2021134004A1 (en) 2021-07-01
TW202136270A (zh) 2021-10-01
EP4081526A1 (en) 2022-11-02
US20240018157A1 (en) 2024-01-18
IL294214A (en) 2022-08-01
BR112022012684A2 (pt) 2023-03-07
CN114945571A (zh) 2022-08-26

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