PE20091688A1 - Derivados de isosorbidos como modificadores del sabor, estimulantes del gusto y mejoradores del sabor - Google Patents

Derivados de isosorbidos como modificadores del sabor, estimulantes del gusto y mejoradores del sabor

Info

Publication number
PE20091688A1
PE20091688A1 PE2009000325A PE2009000325A PE20091688A1 PE 20091688 A1 PE20091688 A1 PE 20091688A1 PE 2009000325 A PE2009000325 A PE 2009000325A PE 2009000325 A PE2009000325 A PE 2009000325A PE 20091688 A1 PE20091688 A1 PE 20091688A1
Authority
PE
Peru
Prior art keywords
flavor
furan
alkyl
isosorbides
derivatives
Prior art date
Application number
PE2009000325A
Other languages
English (en)
Inventor
Catherine Tachdjian
Donald S Karanewsky
Sara L Adamski-Werner
Jeffrey M Yamamoto
Guy Servant
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of PE20091688A1 publication Critical patent/PE20091688A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/205—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/205—Heterocyclic compounds
    • A23L27/2052—Heterocyclic compounds having oxygen or sulfur as the only hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Seasonings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

REFERIDA A UN DERIVADO DE AMIDA DE FORMULA (I), DONDE A ES ARILO C6-C12, HETEROARILO DE 5 O 6 MIEMBROS O UN ENLACE COVALENTE; Y ES H, ALQUILO C1-C6, ALQUENILO C2-C7, ARILO C6-C12, ENTRE OTROS; X ES O, S, S(O), C(O), ENTRE OTROS; Z ES ALQUILO C1-C6, ALQUENILO C2-C7, ALQUINILO C2-C7, ENTRE OTROS. SON COMPUESTOS PREFERIDOS: N-((3S,3aR,6S,6aR)-6-(4-(CICLOHEXILMETIL)-1H-1,2,3-TRIAZOL-1-IL)-HEXAHIDROFURO[3,2-b]FURAN-3-IL)PICOLINAMIDA, N-((3S,3aR,6S,6aR)-6-(4-(CICLOHEXILMETIL)-1H-1,2,3-TRIAZOL-1-IL)-HEXAHIDROFURO[3,2-b]FURAN-3-IL)FURAN-2-CARBOXAMIDA, (N-((3S,3aR,6S,6aR)-6-(4-(CICLOHEXILMETIL)-1H-1,2,3-TRIAZOL-1-IL)-HEXAHIDROFURO[3,2-b]FURAN-3-IL)FURAN-3-CARBOXAMIDA, ENTRE OTROS. TAMBIEN ESTA REFERIDA A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON UTILES COMO MODIFICADORES DEL SABOR O EL GUSTO, PARTICULARMENTE, DEL SABOR SABROSO (UMAMI) EN ALIMENTOS, BEBIDAS Y OTROS COMESTIBLES
PE2009000325A 2008-03-03 2009-03-03 Derivados de isosorbidos como modificadores del sabor, estimulantes del gusto y mejoradores del sabor PE20091688A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3314008P 2008-03-03 2008-03-03
US13942108P 2008-12-19 2008-12-19

Publications (1)

Publication Number Publication Date
PE20091688A1 true PE20091688A1 (es) 2009-12-06

Family

ID=41013365

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2009000325A PE20091688A1 (es) 2008-03-03 2009-03-03 Derivados de isosorbidos como modificadores del sabor, estimulantes del gusto y mejoradores del sabor

Country Status (16)

Country Link
US (2) US8420145B2 (es)
EP (1) EP2254891A4 (es)
JP (1) JP5629217B2 (es)
KR (1) KR101644197B1 (es)
CN (1) CN102083836B (es)
AU (1) AU2009222045A1 (es)
BR (1) BRPI0909097A2 (es)
CA (1) CA2716741A1 (es)
CO (1) CO6310999A2 (es)
IL (1) IL207922A0 (es)
MX (1) MX2010009696A (es)
MY (1) MY153303A (es)
PE (1) PE20091688A1 (es)
RU (1) RU2010140406A (es)
TW (1) TWI429404B (es)
WO (1) WO2009111447A2 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2199294A1 (en) * 2008-12-19 2010-06-23 Lacer, S.A. New stereospecific method for the preparation of dioxa bicyclooctane nitrate compounds
EP2448944A4 (en) * 2009-07-02 2012-11-28 Senomyx Inc Isomannide derivatives and their use as flavorings
AU2011317143A1 (en) * 2010-10-19 2013-05-30 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
CN102241687A (zh) * 2011-05-23 2011-11-16 中国人民解放军第四军医大学 抗缺血/再灌注损伤的药物
WO2013158928A2 (en) 2012-04-18 2013-10-24 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
EP2945950B1 (en) 2013-01-17 2017-03-01 Sanofi Isomannide derivatives as inhibitors of soluble epoxide hydrolase
WO2016022944A1 (en) * 2014-08-08 2016-02-11 Central Michigan University Flame retardants from renewable resources
BR112018006471B1 (pt) 2015-10-01 2024-02-27 Senomyx, Inc Composto, composição, método de modular o membro de melastina do canal potencial do receptor transitório 8 (trpm8), método de modular a sensação de resfrescância de uma composição e método de induzir uma sensação de refrescância em um ser humano ou animal
CA3003163A1 (en) 2015-10-29 2017-05-04 Senomyx, Inc. High intensity sweeteners
WO2018195098A1 (en) 2017-04-17 2018-10-25 Ohio State Innovation Foundation Type ii topoisomerase inhibitors and methods of making and using thereof
MX2019012940A (es) 2017-05-03 2019-12-16 Firmenich Incorporated Metodos para producir edulcorantes de alta intensidad.
KR102099795B1 (ko) * 2017-11-30 2020-04-13 주식회사 삼양사 무수당 알코올 핵을 갖는 화합물 및 이의 제조 방법
KR102162477B1 (ko) * 2018-01-05 2020-10-07 주식회사 삼양사 무수당 알코올 핵 및 알킬렌 옥사이드 연장부를 갖는 화합물 및 이의 제조 방법
EP3806661A1 (en) 2018-08-10 2021-04-21 Firmenich Incorporated Antagonists of t2r54 and compositions and uses thereof
TR201904664A2 (tr) * 2019-03-28 2019-04-22 Osman Oener Muhtelif Rahatsızlıkların Giderilmesi Ve Önlenmesinde Kullanılmak Üzere İlaç, Kozmetik Ve Gıda Takviyesi (Supplement) Olarak Kullanıma Uygun İnsan Ve/Veya Hayvan Kaynaklı Bir Süt Ürünü
EP4093216A4 (en) * 2020-01-24 2024-01-10 Ohio State Innovation Foundation ISOMANNIDE-DERIVED BACTERIAL TOPOISOMERASE INHIBITORS

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE793113A (fr) 1971-12-22 1973-06-21 Montedison Fibre Spa Polyamides lineaires et leur procede de preparation
JPS5937814B2 (ja) 1976-07-26 1984-09-12 富士写真フイルム株式会社 写真感光材料
FR2672051B1 (fr) * 1991-01-24 1993-05-21 Guerbet Sa Nouveaux ligands macrocycliques azotes, procede de preparation, complexes polymetalliques, composition de diagnostic et therapeutique.
ATE176668T1 (de) * 1993-07-23 1999-02-15 Merrell Pharma Inc Neue 9-n-bicyclische nucleosidverbindungen nützlich als selektive inhibitoren von proinflammatorische cytokinen
US5674522A (en) * 1993-10-07 1997-10-07 Mcneil-Ppc, Inc. Beverage concentrate for drug delivery
WO2004096919A1 (ja) 1997-04-07 2004-11-11 Masahiro Suzuki 樹脂組成物及び接着フィルム
TW593241B (en) 1999-04-20 2004-06-21 Hoffmann La Roche Carbamic acid derivatives
US6399641B1 (en) 2000-07-13 2002-06-04 Hoffmann-La Roche Inc. 2H-tetrazole-amide compounds with therapeutic activity as metabotropic glutamate receptor agonists
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
EP2003451B1 (en) 2001-06-26 2012-05-30 Senomyx, Inc. T1r1-t1r3 hetero-oligomeric umami taste receptors and cell lines that express said receptors and use thereof for identification of umami taste compounds
TW555837B (en) * 2001-07-02 2003-10-01 Merck Patent Gmbh Chiral compounds
WO2003027119A1 (en) * 2001-09-24 2003-04-03 Koninklijke Philips Electronics N.V. Isosorbide derivatives
AU2003249212C1 (en) * 2002-07-15 2011-10-27 Symphony Evolution, Inc. Receptor-type kinase modulators and methods of use
CA2900181C (en) 2003-08-06 2019-01-29 Catherine Tachdjian Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
RU2410383C2 (ru) * 2005-02-04 2011-01-27 Синомикс, Инк. Соединения, включающие связанные гетероарильные фрагменты, и их применение в качестве новых модификаторов вкусо-аромата умами, тастантов (стимуляторов сенсорных клеток вкусовых сосочков языка) и усилителей вкуса в пищевых композициях
DE102006018912A1 (de) 2006-04-19 2007-10-25 Analyticon Discovery Gmbh 1,4:3,6-Dianhydromannitol-Derivate und deren Verwendung
JP2008013506A (ja) 2006-07-07 2008-01-24 Osaka Prefecture Univ フラン誘導体の製造方法
GB0614044D0 (en) * 2006-07-14 2006-08-23 Amura Therapeutics Ltd Compounds
US20090018300A1 (en) * 2007-07-11 2009-01-15 Archer-Daniels-Midland Company Monomers and polymers from bioderived carbon

Also Published As

Publication number Publication date
WO2009111447A2 (en) 2009-09-11
AU2009222045A1 (en) 2009-09-11
CN102083836B (zh) 2015-01-28
RU2010140406A (ru) 2012-04-10
TWI429404B (zh) 2014-03-11
US20090220662A1 (en) 2009-09-03
TW200939973A (en) 2009-10-01
KR101644197B1 (ko) 2016-07-29
EP2254891A4 (en) 2011-07-27
US20130295261A1 (en) 2013-11-07
JP5629217B2 (ja) 2014-11-19
JP2011514903A (ja) 2011-05-12
US8420145B2 (en) 2013-04-16
IL207922A0 (en) 2010-12-30
MX2010009696A (es) 2011-02-25
CA2716741A1 (en) 2009-09-11
MY153303A (en) 2015-01-29
WO2009111447A3 (en) 2009-11-26
EP2254891A2 (en) 2010-12-01
CN102083836A (zh) 2011-06-01
BRPI0909097A2 (pt) 2015-09-29
CO6310999A2 (es) 2011-08-22
KR20100121536A (ko) 2010-11-17

Similar Documents

Publication Publication Date Title
PE20091688A1 (es) Derivados de isosorbidos como modificadores del sabor, estimulantes del gusto y mejoradores del sabor
PE20110995A1 (es) DERIVADOS DE PIRROLO[3,4-e]PIRIMIDINA COMO INHIBIDORES DE PDE1
PE20051145A1 (es) Compuestos de 5-,6-dialquil-7-amino-triazolopirimidinas
PE20091116A1 (es) Derivados de piridina y pirazina como inhibidores de tirosina quinasas
PE20060479A1 (es) Compuestos heteroaril-aril-ureas como inhibidores de la quinasa
PE20090362A1 (es) Derivados de piperidina/piperazina como moduladores de dgat
RU2013125846A (ru) Соединения, пригодные в качестве модуляторов trpm8
MY155836A (en) Thienopyridone derivatives as amp-activated protein kinase (ampk) activators
PE20121335A1 (es) Compuestos derivados de amida como inhibidores de raf cinasas
EA200700168A1 (ru) Производные замещенной циклической мочевины, их получение и их фармацевтическое применение в качестве ингибиторов киназы
WO2006106423A8 (en) Amino sulfonyl derivatives as inhibitors of human 11-.beta.-hydrosysteroid dehydrogenase
SG160335A1 (en) Heterocyclic compounds as sweetener enhancers
PE20161066A1 (es) Derivados de piperidinil-indol como inhibidores del factor de complemento b y usos de los mismos
PE20191204A1 (es) Modificador del sabor dulce
EA201001733A1 (ru) Производные тиенопиридона в качестве активаторов амр-активированной протеинкиназы (амрк)
PE20170528A1 (es) Compuestos de carbamoilpiridona policiclicos y su uso farmaceutico
PE20140927A1 (es) Compuestos heterociclicos como inhibidores de cinasas
NI201200084A (es) Derivados de sulfonamidas heterocíclicos útiles como inhibidores de mek
PE20091486A1 (es) Derivado de pirrolopirimidina como inhibidor de la enzima pi3k
PE20091081A1 (es) Piperazino-dihidrotienopirimidinas sustituidas como inhibidores de pde4
PE20060334A1 (es) Derivados de piridina como antagonistas del receptor a2b de adenosina
ATE534626T1 (de) Piperazinamidine als antivirale mittel
PE20110122A1 (es) COMPUESTOS DERIVADOS DE 9H-PIRROLO[2,3-b:5,4-c]DIPIRIDIN-6-(PIRIDIN-3-IL) COMO INHIBIDORES DE LAS CINASA Pim
PE20091414A1 (es) FURO [3,2-c] PIRIDINA Y TIENO [3,2-c] PIRIDINAS
WO2006065590A3 (en) Pyridine and pyrimidine antiviral compositions

Legal Events

Date Code Title Description
FA Abandonment or withdrawal