PE20050290A1 - Composicion que comprende 8-hidroxi-5-[(1r)-1-hidroxi-2-[[(1r)-2-(4-metoxifenil)-1-metiletil]amino]etil-2(1h)-quinolinona y budesonida - Google Patents

Composicion que comprende 8-hidroxi-5-[(1r)-1-hidroxi-2-[[(1r)-2-(4-metoxifenil)-1-metiletil]amino]etil-2(1h)-quinolinona y budesonida

Info

Publication number
PE20050290A1
PE20050290A1 PE2004000199A PE2004000199A PE20050290A1 PE 20050290 A1 PE20050290 A1 PE 20050290A1 PE 2004000199 A PE2004000199 A PE 2004000199A PE 2004000199 A PE2004000199 A PE 2004000199A PE 20050290 A1 PE20050290 A1 PE 20050290A1
Authority
PE
Peru
Prior art keywords
hydroxy
quinolinone
budesonide
amino
refers
Prior art date
Application number
PE2004000199A
Other languages
English (en)
Inventor
Roberta Razzetti
Fiorella Pastore
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32748803&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20050290(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of PE20050290A1 publication Critical patent/PE20050290A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIEREA UNA COMBINACION, CARACTERIZADA PORQUE COMPRENDE: (a) UN AGONISTA ß-2: 8-HIDROXI-5-[(1R)-1-HIDROXI-2-[[(1R)-2-(4-METOXIFENIL)-1-METILETIL]AMINO]ETIL-2(1H)-QUINOLINONA (TA 2005), EN FORMA DE CLORHIDRATO EN UN RANGO DE 0,5 A 8 UG Y (b) UN CORTICOSTEROIDE PARA EL TRATAMIENTO DE LAS ENFERMEDADES INFLAMATORIAS U OBSTRUCTIVAS DE LAS VIAS AEREAS. SELECCIONADO ENTRE BUDESONIDA Y EPIMEROS DE LA MISMA, DIPROPIONATO DE BECLOMETASONA, PROPIONATO DE FLUTICASONA, FLUNISOLIDA, ENTRE OTROS, PARA UNA ADMINISTRACION SIMULTANEA, CONSECUTIVA O SEPARADA, DICHOS COMPUESTOS SE ENCUENTRAN EN LA RELACION DE PESOS ENTRE 1:3200 Y 1:10. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE LOS CONTIENE PARA SER ADMINISTRADA CON UN INHALADOR PRESURIZADO DE DOSIS MEDIDAS , DONDE LOS INGREDIENTES ACTIVOS SE ENCUENTRAN EN SOLUCION O EN SUSPENSION EN UN GAS PROPELENTE O PUEDEN ENCONTRARSE EN LA FORMA DE POLVO SECO. ADEMAS SE REFIERE A UNA PREPARACION COMBINADA QUE CONTIENE EL COMPUESTO (a) Y UN DERIVADO ANTICOLINERGICO DE TIPO ATROPINA SELECCIONADO DE BROMURO DE IPATROPIO, DE OXITROPIO, Y DE TIOTROPIO. ESTAS COMBINACIONES SON UTILES PARA EL TRATAMIENTO DE TRANSTORNOS RESPIRATORIOS Y EN ESPECIAL DEL ASMA Y ENFERMEDAD OBSTRUCTIVA CRONICA (COPD)
PE2004000199A 2003-02-27 2004-02-26 Composicion que comprende 8-hidroxi-5-[(1r)-1-hidroxi-2-[[(1r)-2-(4-metoxifenil)-1-metiletil]amino]etil-2(1h)-quinolinona y budesonida PE20050290A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03004184A EP1452179A1 (en) 2003-02-27 2003-02-27 Novel medicament combination of a highly potent long-lasting beta2-agonist and a corticosteroid

Publications (1)

Publication Number Publication Date
PE20050290A1 true PE20050290A1 (es) 2005-05-26

Family

ID=32748803

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2004000199A PE20050290A1 (es) 2003-02-27 2004-02-26 Composicion que comprende 8-hidroxi-5-[(1r)-1-hidroxi-2-[[(1r)-2-(4-metoxifenil)-1-metiletil]amino]etil-2(1h)-quinolinona y budesonida

Country Status (32)

Country Link
US (1) US20070020190A1 (es)
EP (3) EP1452179A1 (es)
JP (1) JP2006519204A (es)
KR (1) KR20050104367A (es)
CN (2) CN100370986C (es)
AR (1) AR043419A1 (es)
AT (1) ATE401887T1 (es)
AU (1) AU2004216472B2 (es)
BR (1) BRPI0408047A (es)
CA (1) CA2517321A1 (es)
CY (1) CY1108360T1 (es)
DE (1) DE602004015260D1 (es)
DK (1) DK1603565T3 (es)
EA (1) EA008828B1 (es)
ES (1) ES2309503T3 (es)
HK (1) HK1087009A1 (es)
HR (1) HRP20050726A2 (es)
MA (1) MA27630A1 (es)
ME (1) MEP32208A (es)
MX (1) MXPA05009007A (es)
NO (1) NO20053959L (es)
NZ (1) NZ541997A (es)
PE (1) PE20050290A1 (es)
PL (1) PL377814A1 (es)
PT (1) PT1603565E (es)
RS (1) RS20050615A (es)
SA (1) SA04250122B1 (es)
SI (1) SI1603565T1 (es)
TN (1) TNSN05186A1 (es)
UA (1) UA82217C2 (es)
WO (1) WO2004075896A1 (es)
ZA (1) ZA200506820B (es)

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ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US20060257324A1 (en) * 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
JP2007500676A (ja) * 2003-07-31 2007-01-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗コリン作用薬とベータ受容体刺激薬を含む吸入用薬剤
CA2534693A1 (en) * 2003-08-05 2005-02-17 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising steroids and a betamimetic
EP1670482B2 (en) 2003-09-16 2022-06-29 Covis Pharma B.V. Use of ciclesonide for the treatment of respiratory diseases
MX2007011273A (es) * 2005-03-16 2007-11-08 Meda Pharma Gmbh & Co Kg La combinacion de anticolinergicos y antagonistas del receptor de leucotrieno para el tratamiento de enfermedades respiratorias.
WO2006105401A2 (en) * 2005-03-30 2006-10-05 Schering Corporation Medicaments and methods combining an anticholinergic, a corticosteroid, and a long acting beta agonist
JP2009502997A (ja) * 2005-08-01 2009-01-29 シエシー ファルマセウティチィ ソシエタ ペル アチオニ 噴霧投与用の長時間作用型ベータ２−アゴニストを含む医薬製剤
JP5257073B2 (ja) * 2005-11-10 2013-08-07 ボーダー、ニコラス・エス ソフト型抗コリン作動性エステル
AU2006329042B2 (en) * 2005-12-21 2012-02-02 Meda Pharma Gmbh & Co Kg Combination of anticholinergics, glucocorticoids, beta2-agonists, PDE4 inhibitor and antileukotriene for the treatment of inflammatory diseases
JP2010526763A (ja) * 2006-05-24 2010-08-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器系疾患を治療するための新規な長時間作用型の薬剤組成物
EP1953143A1 (en) * 2007-01-30 2008-08-06 CHIESI FARMACEUTICI S.p.A. Process for the preparation of 8-hydroxy-5-[(1R)-1-hydroxy-2[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone monohydrochloride
WO2008102128A2 (en) * 2007-02-19 2008-08-28 Cipla Limited Pharmaceutical combinations of at least two bronchodilators or of a bronchodilator with a corticosteroid
EP2534957B1 (en) 2007-12-14 2015-05-27 AeroDesigns, Inc Delivering aerosolizable products
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
WO2010013240A1 (en) 2008-07-31 2010-02-04 Dekel Pharmaceuticals Ltd. Compositions and methods for treating inflammatory disorders
WO2010097188A1 (en) * 2009-02-25 2010-09-02 Chiesi Farmaceutici S.P.A. Inhalation particles comprising a salt of carmoterol and a corticosteroid
CA2763402A1 (en) * 2009-05-25 2010-12-02 Chiesi Farmaceutici S.P.A. A therapeutic combination comprising a pulmonary surfactant and a steroid
AU2015201037C1 (en) * 2009-05-29 2017-07-27 Pearl Therapeutics, Inc. Respiratory delivery of active agents
RU2580315C3 (ru) 2009-05-29 2021-06-18 Перл Терапьютикс, Инк. Композиции для респираторной доставки активных веществ и связанные с ними способы и системы
EP2563364A1 (en) * 2010-04-26 2013-03-06 Mahmut Bilgic Combination of carmoterol and fluticasone for use in the treatment respiratory diseases
CN102247597B (zh) * 2010-05-19 2015-01-07 天津金耀集团有限公司 一种糖皮质激素与支气管扩张剂的吸入剂
EP3871676A1 (en) 2010-07-16 2021-09-01 Cipla Limited Pharmaceutical compositions comprising r(+) budesonide and arformoterol
WO2012010854A1 (en) 2010-07-23 2012-01-26 Cipla Limited Inhalation formulations comprising carmoterol in combination with a corticosteroid
CN102416179B (zh) * 2010-09-28 2014-05-07 益得生物科技股份有限公司 用于哮喘的吸入性复方组合物
TWI399202B (zh) * 2011-03-17 2013-06-21 Intech Biopharm Ltd 製備用於治療呼吸道疾病之定量噴霧吸入劑的製程方法
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HUE037275T2 (hu) * 2013-03-15 2018-08-28 Verona Pharma Plc Gyógyszer-kombináció
EP3193862B1 (en) 2014-09-16 2023-10-18 Igc Pharma Ip, Llc Topical cannabinoid composition for treating arthritic pain
ES2895850T3 (es) * 2014-11-24 2022-02-22 Univ Illinois Procedimiento de prevención o tratamiento de una enfermedad o afección pulmonar
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Also Published As

Publication number Publication date
CA2517321A1 (en) 2004-09-10
US20070020190A1 (en) 2007-01-25
CN101244063A (zh) 2008-08-20
AU2004216472A1 (en) 2004-09-10
EA200501108A1 (ru) 2006-04-28
KR20050104367A (ko) 2005-11-02
NO20053959L (no) 2005-11-28
HK1087009A1 (en) 2006-10-06
ES2309503T3 (es) 2008-12-16
RS20050615A (en) 2007-09-21
WO2004075896A1 (en) 2004-09-10
EP1834643A3 (en) 2007-10-24
UA82217C2 (uk) 2008-03-25
EP1834643A2 (en) 2007-09-19
NZ541997A (en) 2008-12-24
EP1452179A1 (en) 2004-09-01
AU2004216472B2 (en) 2009-08-06
CN100370986C (zh) 2008-02-27
PL377814A1 (pl) 2006-02-20
BRPI0408047A (pt) 2006-02-14
PT1603565E (pt) 2008-10-06
SA04250122B1 (ar) 2009-03-11
JP2006519204A (ja) 2006-08-24
DE602004015260D1 (de) 2008-09-04
EP1603565A1 (en) 2005-12-14
ATE401887T1 (de) 2008-08-15
AR043419A1 (es) 2005-07-27
TNSN05186A1 (en) 2007-06-11
MA27630A1 (fr) 2005-11-01
CY1108360T1 (el) 2014-02-12
HRP20050726A2 (en) 2006-02-28
EP1603565B1 (en) 2008-07-23
SI1603565T1 (sl) 2008-10-31
DK1603565T3 (da) 2008-11-10
CN1753678A (zh) 2006-03-29
NO20053959D0 (no) 2005-08-25
ZA200506820B (en) 2006-11-29
EA008828B1 (ru) 2007-08-31
MEP32208A (en) 2010-10-10
MXPA05009007A (es) 2005-10-18

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