PE20040848A1 - Formulacion pulverulenta que contiene tiotropio destinada a la inhalacion - Google Patents
Formulacion pulverulenta que contiene tiotropio destinada a la inhalacionInfo
- Publication number
- PE20040848A1 PE20040848A1 PE2003001200A PE2003001200A PE20040848A1 PE 20040848 A1 PE20040848 A1 PE 20040848A1 PE 2003001200 A PE2003001200 A PE 2003001200A PE 2003001200 A PE2003001200 A PE 2003001200A PE 20040848 A1 PE20040848 A1 PE 20040848A1
- Authority
- PE
- Peru
- Prior art keywords
- formulation containing
- inhalation
- tiotrope
- intended
- substance
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
- A61M15/0026—Hinged caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
SE REFIERE A UNA FORMULACION QUE CONTIENE: a) DE 0,001 A 3% DE TIOTROPIO EN FORMA DE CLORURO, BROMURO, YODURO, METANOSULFONATO Y b) UNA SUSTANCIA COADYUVANTE INOCUA CARACTERIZADO PORQUE LA SUSTANCIA COADYUVANTE PRESENTA UN TAMANO MEDIO DE PARTICULAS DE 10-50 um, UNA PORCION FINA DEL 10% DE 0,5 A 6 um ASI COMO UNA SUPERFICIE ESPECIFICA DE 0,1 A 2 m2/g. LA SUSTANCIA INOCUA SE SELECCIONA DE GLUCOSA, ARABINOSA, LACTOSA, ENTRE OTROS. SE REFIERE ADEMAS A UN ESTUCHE PARA INHALACION QUE CONSTA DE UNA CAPSULA Y DE UN INHALADOR. LA FORMULACION ES UTIL PARA EL TRATAMIENTO DE ENFERMEDADES DE LAS VIAS RESPIRATORIAS, ENFERMEDAD PULMONAR OBSTRUCTIVA CRONICA (EPOC)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10255387A DE10255387A1 (de) | 2002-11-28 | 2002-11-28 | Neue Tiotropium-haltige Pulverformulierung für die Inhalation |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20040848A1 true PE20040848A1 (es) | 2005-01-14 |
Family
ID=32308760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2003001200A PE20040848A1 (es) | 2002-11-28 | 2003-11-26 | Formulacion pulverulenta que contiene tiotropio destinada a la inhalacion |
Country Status (34)
Country | Link |
---|---|
EP (1) | EP1567135B1 (es) |
JP (1) | JP4977321B2 (es) |
KR (1) | KR101066805B1 (es) |
CN (1) | CN100574751C (es) |
AR (1) | AR042242A1 (es) |
AT (1) | ATE401861T1 (es) |
AU (1) | AU2003294714B2 (es) |
BR (1) | BR0316343A (es) |
CA (1) | CA2507579C (es) |
CO (1) | CO5580736A2 (es) |
CY (1) | CY1108420T1 (es) |
DE (2) | DE10255387A1 (es) |
DK (1) | DK1567135T3 (es) |
EA (1) | EA011549B1 (es) |
EC (1) | ECSP055821A (es) |
ES (1) | ES2310681T3 (es) |
HK (1) | HK1085918A1 (es) |
HR (1) | HRP20050468A2 (es) |
IL (1) | IL168810A (es) |
ME (1) | MEP51608A (es) |
MX (1) | MXPA05005485A (es) |
MY (1) | MY140890A (es) |
NO (1) | NO20053090D0 (es) |
PE (1) | PE20040848A1 (es) |
PL (1) | PL376229A1 (es) |
PT (1) | PT1567135E (es) |
RS (1) | RS20050400A (es) |
SA (1) | SA04240467B1 (es) |
SI (1) | SI1567135T1 (es) |
TW (1) | TWI332837B (es) |
UA (1) | UA81930C2 (es) |
UY (1) | UY28096A1 (es) |
WO (1) | WO2004047796A2 (es) |
ZA (1) | ZA200502859B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006016904A1 (de) * | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator |
DE102008014025A1 (de) * | 2008-03-13 | 2009-09-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator und Sieb für einen Inhalator |
TR200909788A2 (tr) | 2009-12-25 | 2011-07-21 | Bi̇lgi̇ç Mahmut | Tiotropyum içeren inhalasyona uygun kuru toz formülasyonu |
PT2600830T (pt) * | 2010-08-03 | 2018-04-02 | Chiesi Farm Spa | Formulação de pó seco que compreende um inibidor de fosfodiesterase |
WO2014074797A1 (en) * | 2012-11-09 | 2014-05-15 | Civitas Therapeutics, Inc. | Ultra low density pulmonary powders |
KR101748796B1 (ko) * | 2015-09-30 | 2017-06-19 | 한미약품 주식회사 | 활성성분의 전달량이 향상된 흡입용 캡슐제 |
KR101728116B1 (ko) * | 2015-11-03 | 2017-04-18 | 한미약품 주식회사 | 티오트로피움 또는 이의 약학적으로 허용가능한 염을 함유하는 흡입용 건조분말 조성물 |
CN111514418B (zh) * | 2019-06-12 | 2022-01-14 | 中南大学湘雅二医院 | 一种自吸式经鼻粉末材料给送装置 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1242211A (en) * | 1967-08-08 | 1971-08-11 | Fisons Pharmaceuticals Ltd | Pharmaceutical composition |
DE4140689B4 (de) * | 1991-12-10 | 2007-11-22 | Boehringer Ingelheim Kg | Inhalationspulver und Verfahren zu ihrer Herstellung |
DE4318455A1 (de) * | 1993-06-03 | 1994-12-08 | Boehringer Ingelheim Kg | Kapselhalterung |
GB9322014D0 (en) * | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
DE4425255A1 (de) * | 1994-07-16 | 1996-01-18 | Asta Medica Ag | Formulierung zur inhalativen Applikation |
PT1283036E (pt) * | 1998-11-13 | 2008-03-06 | Jagotec Ag | Inalador de pó seco de dose múltipla com um reservatório de pó |
GB9902689D0 (en) * | 1999-02-08 | 1999-03-31 | Novartis Ag | Organic compounds |
UA75375C2 (en) * | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
WO2002030389A1 (de) * | 2000-10-12 | 2002-04-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue tiotropium-haltige inhalationspulver |
DE10126924A1 (de) * | 2001-06-01 | 2002-12-05 | Boehringer Ingelheim Pharma | Inhalationskapseln |
DE10141377A1 (de) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Aufstreuverfahren zur Herstellung von Pulverformulierungen |
DK1494648T3 (da) * | 2002-04-04 | 2006-12-27 | Boehringer Ingelheim Pharma | Pulverpræparat til inhalation |
UA80123C2 (en) * | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
-
2002
- 2002-11-28 DE DE10255387A patent/DE10255387A1/de not_active Withdrawn
-
2003
- 2003-11-19 MX MXPA05005485A patent/MXPA05005485A/es active IP Right Grant
- 2003-11-19 BR BR0316343-1A patent/BR0316343A/pt active Pending
- 2003-11-19 ME MEP-516/08A patent/MEP51608A/xx unknown
- 2003-11-19 WO PCT/EP2003/012911 patent/WO2004047796A2/de active IP Right Grant
- 2003-11-19 AU AU2003294714A patent/AU2003294714B2/en not_active Expired
- 2003-11-19 AT AT03785648T patent/ATE401861T1/de active
- 2003-11-19 EP EP03785648A patent/EP1567135B1/de not_active Revoked
- 2003-11-19 DE DE50310208T patent/DE50310208D1/de not_active Expired - Lifetime
- 2003-11-19 PT PT03785648T patent/PT1567135E/pt unknown
- 2003-11-19 DK DK03785648T patent/DK1567135T3/da active
- 2003-11-19 PL PL03376229A patent/PL376229A1/xx unknown
- 2003-11-19 UA UAA200506224A patent/UA81930C2/uk unknown
- 2003-11-19 CA CA2507579A patent/CA2507579C/en not_active Expired - Fee Related
- 2003-11-19 SI SI200331323T patent/SI1567135T1/sl unknown
- 2003-11-19 EA EA200500864A patent/EA011549B1/ru not_active IP Right Cessation
- 2003-11-19 ES ES03785648T patent/ES2310681T3/es not_active Expired - Lifetime
- 2003-11-19 KR KR1020057009548A patent/KR101066805B1/ko active IP Right Grant
- 2003-11-19 RS YUP-2005/0400A patent/RS20050400A/sr unknown
- 2003-11-19 CN CN200380104599A patent/CN100574751C/zh not_active Expired - Lifetime
- 2003-11-19 JP JP2004554384A patent/JP4977321B2/ja not_active Expired - Lifetime
- 2003-11-26 UY UY28096A patent/UY28096A1/es not_active Application Discontinuation
- 2003-11-26 TW TW092133185A patent/TWI332837B/zh not_active IP Right Cessation
- 2003-11-26 PE PE2003001200A patent/PE20040848A1/es not_active Application Discontinuation
- 2003-11-27 MY MYPI20034544A patent/MY140890A/en unknown
- 2003-11-28 AR ARP030104393A patent/AR042242A1/es active Pending
-
2004
- 2004-01-03 SA SA04240467A patent/SA04240467B1/ar unknown
-
2005
- 2005-04-08 ZA ZA200502859A patent/ZA200502859B/en unknown
- 2005-05-26 EC EC2005005821A patent/ECSP055821A/es unknown
- 2005-05-26 IL IL168810A patent/IL168810A/en not_active IP Right Cessation
- 2005-05-27 HR HR20050468A patent/HRP20050468A2/xx not_active Application Discontinuation
- 2005-06-23 NO NO20053090A patent/NO20053090D0/no not_active Application Discontinuation
- 2005-06-27 CO CO05062904A patent/CO5580736A2/es not_active Application Discontinuation
-
2006
- 2006-05-23 HK HK06105905.7A patent/HK1085918A1/xx not_active IP Right Cessation
-
2008
- 2008-10-16 CY CY20081101149T patent/CY1108420T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Ozlü et al. | Smoking and lung cancer | |
ECSP024268A (es) | Nuevos polvos para inhalacion que contienen tiotropio | |
NO20054767L (no) | Sammensetninger omfattende apomorfin for inhalering i lunge | |
ECSP055855A (es) | Medicamentos en polvo para inhalación que contiene una sal de tiotropio y salmeterolxinafoato | |
SG169233A1 (en) | Pharmaceutical compositions comprising apomorphine for pulmonary inhalation | |
UY28908A1 (es) | Dispositivo inhalador de medicamentos | |
ATE330589T1 (de) | Pharmazeutische zusammensetzung enthaltend resveratrol zur behandlung von entzündlichen erkrankungen der atemwege | |
JP2007518801A5 (es) | ||
JP2005530743A5 (es) | ||
MY153408A (en) | Novel methods | |
UA101652C2 (uk) | Композиція для інгаляції, що містить аклідиній для лікування астми та хронічного обструктивного захворювання легень | |
PE20040848A1 (es) | Formulacion pulverulenta que contiene tiotropio destinada a la inhalacion | |
NO20073909L (no) | Forstover-formulering | |
NO20083683L (no) | Nebulisatorformulering | |
PE20050485A1 (es) | Nuevas sales de tiotropio, procedimiento para su preparacion, asi como formulaciones medicamentosas que las contienen | |
HK1074582A1 (en) | Use of glycosaminoglycans such as e.g. heparin for the treatment of respiratory disorders such as copd | |
EA200701077A1 (ru) | Применение конъюгатов липидов при лечении заболеваний | |
TW200616536A (en) | Animal for drug efficacy evaluation, method for developing chronic obstructive pulmonary disease in animal for drug efficacy evaluation, and method for evaluation drug efficacy using the animal | |
UY28590A1 (es) | Procedimiento para la preparación de nuevas sales de tiotropio, nuevas sales de tiotropio como tales, así como las formulaciones medicamentosas que las contienen. | |
MXPA02012755A (es) | Uso de ligandos del receptor de la secretina en el tratamiento de la fibrosis quistica y la enfermedad pulmonar obstructiva cronica. | |
NO20074661L (no) | Anvendelse av en forbindelse | |
DK1494648T3 (da) | Pulverpræparat til inhalation | |
CN204033657U (zh) | 一种排气助睡式医疗床 | |
JP2019505538A5 (es) | ||
CN104127290A (zh) | 一种排气助睡式医疗床 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |