MXPA02012755A - Uso de ligandos del receptor de la secretina en el tratamiento de la fibrosis quistica y la enfermedad pulmonar obstructiva cronica. - Google Patents
Uso de ligandos del receptor de la secretina en el tratamiento de la fibrosis quistica y la enfermedad pulmonar obstructiva cronica.Info
- Publication number
- MXPA02012755A MXPA02012755A MXPA02012755A MXPA02012755A MXPA02012755A MX PA02012755 A MXPA02012755 A MX PA02012755A MX PA02012755 A MXPA02012755 A MX PA02012755A MX PA02012755 A MXPA02012755 A MX PA02012755A MX PA02012755 A MXPA02012755 A MX PA02012755A
- Authority
- MX
- Mexico
- Prior art keywords
- secretin
- treatment
- copd
- cystic fibrosis
- pulmonary disease
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2235—Secretins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Abstract
La invencion se basa en el descubrimiento de que se expresa el receptor de la secretina en tejidos presentes en el pulmon distal de los humanos. En pacientes con FQ, se elevan los niveles del receptor comparados con el tejido normal. El tratamiento del tejido por la secretina estimula el movimiento de iones negativos en el tejido. La invencion proporciona metodos para el tratamiento de la fibrosis quistica o EPOC en un paciente por administrar al paciente una cantidad efectiva de un agente el cual acciona la emanacion de aniones en el tejido respiratorio por medio de la activacion de un receptor de la secretina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0016441.8A GB0016441D0 (en) | 2000-07-04 | 2000-07-04 | Therapeutic method |
PCT/GB2001/002989 WO2002002134A1 (en) | 2000-07-04 | 2001-07-04 | Use of secretin-receptor ligands in treatment of cystic fibrosis (cf) and chronic obstructive pulmonary disease (copd) |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02012755A true MXPA02012755A (es) | 2004-09-10 |
Family
ID=9895021
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02012755A MXPA02012755A (es) | 2000-07-04 | 2001-07-04 | Uso de ligandos del receptor de la secretina en el tratamiento de la fibrosis quistica y la enfermedad pulmonar obstructiva cronica. |
Country Status (20)
Country | Link |
---|---|
US (4) | US6780839B2 (es) |
EP (2) | EP1736153B1 (es) |
JP (2) | JP2004501977A (es) |
KR (2) | KR100881931B1 (es) |
CN (2) | CN100584324C (es) |
AT (1) | ATE454145T1 (es) |
AU (1) | AU2001267729A1 (es) |
CA (1) | CA2412839A1 (es) |
CY (1) | CY1109937T1 (es) |
DE (1) | DE60141054D1 (es) |
DK (1) | DK1736153T3 (es) |
ES (1) | ES2341562T3 (es) |
GB (3) | GB0016441D0 (es) |
HK (1) | HK1104959A1 (es) |
MX (1) | MXPA02012755A (es) |
NO (2) | NO20026119L (es) |
NZ (1) | NZ523303A (es) |
PT (1) | PT1736153E (es) |
WO (1) | WO2002002134A1 (es) |
ZA (1) | ZA200210268B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0507577D0 (en) * | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
CN100407816C (zh) * | 2005-07-07 | 2008-07-30 | 华为技术有限公司 | 一种群组呼叫的寻呼方法 |
US8473250B2 (en) | 2006-12-06 | 2013-06-25 | Solaredge, Ltd. | Monitoring of distributed power harvesting systems using DC power sources |
US11569659B2 (en) | 2006-12-06 | 2023-01-31 | Solaredge Technologies Ltd. | Distributed power harvesting systems using DC power sources |
EP2185172A2 (en) * | 2007-09-11 | 2010-05-19 | Mondobiotech Laboratories AG | Use of follicular gonadotropin releasing peptide as a therapeutic agent in the treatment of streptococcus pneumoniae infection |
US20100184676A1 (en) * | 2007-09-11 | 2010-07-22 | Dorian Bevec | Use of a peptide as a therapeutic agent |
US11318190B2 (en) * | 2017-05-05 | 2022-05-03 | United States Government As Represented By The Department Of Veterans Affairs | Methods and compositions for treating liver disease |
RU2721415C1 (ru) * | 2019-09-16 | 2020-05-19 | Федеральное государственное бюджетное научное учреждение Дальневосточный научный центр физиологии и патологии дыхания" | Способ прогнозирования эффективности коррекции холодовой гиперреактивности дыхательных путей у больных бронхиальной астмой при применении экстрамелкодисперсного аэрозоля для ингаляций беклометазона дипропионата/формотерола фумарата |
WO2022065860A1 (ko) * | 2020-09-24 | 2022-03-31 | 충북대학교 산학협력단 | 나파모스타트 또는 카모스타트를 포함하는 흡입용 제제 |
RU2770282C1 (ru) * | 2021-07-26 | 2022-04-15 | Федеральное государственное бюджетное научное учреждение «Дальневосточный научный центр физиологии и патологии дыхания» | Способ диагностики варианта холодовой гиперреактивности дыхательных путей у больных бронхиальной астмой |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3833722A (en) * | 1971-03-16 | 1974-09-03 | D Graybill | Method for controlling allergies |
GB1472700A (en) * | 1974-11-01 | 1977-05-04 | Ono Pharmaceutical Co | Guanidinobehzoic acid derivatives and process for preparing the same |
DE3402466A1 (de) * | 1984-01-25 | 1985-08-01 | Hoechst Ag, 6230 Frankfurt | Sekretin und dieses enthaltende mittel zur prophylaxe des aspirations-syndroms |
ATE101619T1 (de) * | 1990-06-26 | 1994-03-15 | Sanwa Kagaku Kenkyusho Co | Vip-analogen und ihre verwendung. |
GB9318105D0 (en) | 1993-09-01 | 1993-10-20 | Medical Res Council | Receptor action |
AU709559B2 (en) | 1994-04-07 | 1999-09-02 | Proteinix Company | Vasoactive intestinal polypeptide |
ZA971607B (en) | 1996-03-12 | 1998-08-25 | Univ Johns Hopkins | Methods of treatment of allergic diseases |
JPH09309873A (ja) * | 1996-05-22 | 1997-12-02 | Jiyunsei Kagaku Kk | メシル酸カモスタットの新規な製造法 |
WO1998002453A2 (en) | 1996-07-15 | 1998-01-22 | Universite Libre De Bruxelles | Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor |
US6197746B1 (en) | 1998-05-19 | 2001-03-06 | Repligen Corporation | Method of using secretin for treating autism |
JP2002501616A (ja) * | 1997-05-19 | 2002-01-15 | リプリゲン コーポレーション | 自閉的症候群を鑑別診断および治療する際の助けとするための方法 |
US6020314A (en) * | 1998-08-11 | 2000-02-01 | Milkhaus Laboratory, Inc. | Methods for treatment of neurological disorders |
US6926911B1 (en) * | 1998-12-22 | 2005-08-09 | The University Of North Carolina At Chapel Hill | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs |
EP1354603A1 (en) * | 2000-12-26 | 2003-10-22 | Takeda Chemical Industries, Ltd. | Concomitant drugs |
GB0507577D0 (en) * | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
-
2000
- 2000-07-04 GB GBGB0016441.8A patent/GB0016441D0/en not_active Ceased
-
2001
- 2001-07-03 US US09/897,412 patent/US6780839B2/en not_active Expired - Fee Related
- 2001-07-04 EP EP06010364A patent/EP1736153B1/en not_active Expired - Lifetime
- 2001-07-04 NZ NZ523303A patent/NZ523303A/en unknown
- 2001-07-04 JP JP2002506755A patent/JP2004501977A/ja active Pending
- 2001-07-04 CA CA002412839A patent/CA2412839A1/en not_active Abandoned
- 2001-07-04 AU AU2001267729A patent/AU2001267729A1/en not_active Abandoned
- 2001-07-04 EP EP01945514A patent/EP1296708A1/en not_active Withdrawn
- 2001-07-04 MX MXPA02012755A patent/MXPA02012755A/es unknown
- 2001-07-04 CN CN200610059858A patent/CN100584324C/zh not_active Expired - Fee Related
- 2001-07-04 KR KR1020067006902A patent/KR100881931B1/ko not_active IP Right Cessation
- 2001-07-04 PT PT06010364T patent/PT1736153E/pt unknown
- 2001-07-04 AT AT06010364T patent/ATE454145T1/de active
- 2001-07-04 GB GB0409577A patent/GB2397522B/en not_active Expired - Fee Related
- 2001-07-04 DE DE60141054T patent/DE60141054D1/de not_active Expired - Lifetime
- 2001-07-04 GB GB0200416A patent/GB2368795B/en not_active Expired - Fee Related
- 2001-07-04 WO PCT/GB2001/002989 patent/WO2002002134A1/en not_active Application Discontinuation
- 2001-07-04 ES ES06010364T patent/ES2341562T3/es not_active Expired - Lifetime
- 2001-07-04 DK DK06010364.5T patent/DK1736153T3/da active
- 2001-07-04 KR KR10-2003-7000097A patent/KR20030026967A/ko not_active Application Discontinuation
- 2001-07-04 CN CN01815130A patent/CN1452494A/zh active Pending
-
2002
- 2002-12-19 ZA ZA200210268A patent/ZA200210268B/xx unknown
- 2002-12-19 NO NO20026119A patent/NO20026119L/no not_active Application Discontinuation
-
2004
- 2004-04-13 US US10/822,677 patent/US20040191238A1/en not_active Abandoned
-
2006
- 2006-03-03 US US11/366,462 patent/US20060147384A1/en not_active Abandoned
- 2006-03-30 JP JP2006094221A patent/JP2006213728A/ja active Pending
- 2006-04-12 NO NO20061667A patent/NO328406B1/no not_active IP Right Cessation
-
2007
- 2007-06-25 HK HK07106780.4A patent/HK1104959A1/xx unknown
-
2010
- 2010-03-31 CY CY20101100302T patent/CY1109937T1/el unknown
- 2010-11-01 US US12/917,019 patent/US20110039759A1/en not_active Abandoned
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