CY1105116T1 - Χρηση των il-6r/il-6 χιμαιρων στη νοσο του huntington - Google Patents
Χρηση των il-6r/il-6 χιμαιρων στη νοσο του huntingtonInfo
- Publication number
- CY1105116T1 CY1105116T1 CY20061101058T CY061101058T CY1105116T1 CY 1105116 T1 CY1105116 T1 CY 1105116T1 CY 20061101058 T CY20061101058 T CY 20061101058T CY 061101058 T CY061101058 T CY 061101058T CY 1105116 T1 CY1105116 T1 CY 1105116T1
- Authority
- CY
- Cyprus
- Prior art keywords
- huntington
- disease
- chimeras
- derivative
- mutein
- Prior art date
Links
- 208000023105 Huntington disease Diseases 0.000 title abstract 2
- 108090001005 Interleukin-6 Proteins 0.000 title abstract 2
- 102100037792 Interleukin-6 receptor subunit alpha Human genes 0.000 title abstract 2
- 108040006858 interleukin-6 receptor activity proteins Proteins 0.000 title abstract 2
- 102000001708 Protein Isoforms Human genes 0.000 abstract 1
- 108010029485 Protein Isoforms Proteins 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000017105 transposition Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/204—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Abstract
Η εφεύρεση αφορά τη χρήση μιας χίμαιρας IL-6R/IL-6, μιας mutein, ισόμορφης, πρωτεΐνης από σύντηξη, λειτουργικού παραγώγου, δραστικού τμήματος ή παραγώγου κυκλικής μετάθεσης ή άλατος αυτής, για την παρασκευή ενός φαρμάκου για τη θεραπεία ή/και την πρόληψη της νόσου του Huntington.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00120045 | 2000-09-14 | ||
EP01972039A EP1317273B1 (en) | 2000-09-14 | 2001-09-10 | Use of il-6r/il-6 chimera in huntington's disease |
PCT/EP2001/010442 WO2002022149A1 (en) | 2000-09-14 | 2001-09-10 | Use of il-6r/il-6 chimera in huntington's disease |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1105116T1 true CY1105116T1 (el) | 2009-11-04 |
Family
ID=8169836
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061101058T CY1105116T1 (el) | 2000-09-14 | 2006-07-28 | Χρηση των il-6r/il-6 χιμαιρων στη νοσο του huntington |
Country Status (13)
Country | Link |
---|---|
US (3) | US20040057928A1 (el) |
EP (1) | EP1317273B1 (el) |
JP (1) | JP5030364B2 (el) |
AT (1) | ATE324906T1 (el) |
AU (2) | AU2001291849B2 (el) |
CA (1) | CA2419954C (el) |
CY (1) | CY1105116T1 (el) |
DE (1) | DE60119347T2 (el) |
DK (1) | DK1317273T3 (el) |
ES (1) | ES2262680T3 (el) |
IL (2) | IL154777A0 (el) |
PT (1) | PT1317273E (el) |
WO (1) | WO2002022149A1 (el) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL147412A0 (en) * | 2001-12-31 | 2002-08-14 | Yeda Res & Dev | The use of il6r/il6 chimera in nerve cell regeneration |
WO2004037281A1 (en) * | 2002-10-24 | 2004-05-06 | The University Of British Columbia | Methods for neuroprotection |
US7553930B2 (en) | 2003-01-06 | 2009-06-30 | Xencor, Inc. | BAFF variants and methods thereof |
AU2004247961B2 (en) * | 2003-06-12 | 2010-06-24 | Yeda Research & Development Co.Ltd | Enhancement of oligodendrocyte differentiation |
AU2004279895A1 (en) | 2003-10-10 | 2005-04-21 | Xencor, Inc | Protein based TNF-alpha variants for the treatment of TNF-alpha related disorders |
SI2859015T1 (sl) | 2012-06-08 | 2018-12-31 | Alkermes Pharma Ireland Limited | Ligandi, modificirani s cirkularno permutacijo, kot agonisti in antagonisti |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5637483A (en) * | 1991-10-04 | 1997-06-10 | Whitehead Institute For Biomedical Research | Irradiated tumor cell vaccine engineered to express GM-CSF |
IL99803A (en) * | 1991-10-20 | 1997-02-18 | Yeda Res & Dev | Pharmaceutical compositions comprising interleukin-6 for the treatment of chronic lymphocytic leukemia and B-cell lymphomas |
US5792900A (en) * | 1991-10-21 | 1998-08-11 | The Trustees Of The University Of Pennsylvania | Compositions and methods for producing and using homogenous neuronal cell transplants |
IL122818A0 (en) * | 1997-07-10 | 1998-08-16 | Yeda Res & Dev | Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof |
DK1895010T3 (da) * | 1997-12-22 | 2011-11-21 | Oxford Biomedica Ltd | Vektorer baseret på virus for infektiøs hesteanæmi (eiav) |
JP4859153B2 (ja) * | 1999-02-25 | 2012-01-25 | 東ソー株式会社 | 新規神経系細胞分化促進剤 |
IL130586A0 (en) * | 1999-06-21 | 2000-06-01 | Yeda Res & Dev | IL6RIL6 chimera for the treatment of demyelinating diseases |
-
2001
- 2001-09-10 ES ES01972039T patent/ES2262680T3/es not_active Expired - Lifetime
- 2001-09-10 PT PT01972039T patent/PT1317273E/pt unknown
- 2001-09-10 DE DE60119347T patent/DE60119347T2/de not_active Expired - Lifetime
- 2001-09-10 AU AU2001291849A patent/AU2001291849B2/en not_active Ceased
- 2001-09-10 JP JP2002526399A patent/JP5030364B2/ja not_active Expired - Fee Related
- 2001-09-10 CA CA2419954A patent/CA2419954C/en not_active Expired - Lifetime
- 2001-09-10 IL IL15477701A patent/IL154777A0/xx unknown
- 2001-09-10 US US10/380,427 patent/US20040057928A1/en not_active Abandoned
- 2001-09-10 EP EP01972039A patent/EP1317273B1/en not_active Expired - Lifetime
- 2001-09-10 AT AT01972039T patent/ATE324906T1/de active
- 2001-09-10 DK DK01972039T patent/DK1317273T3/da active
- 2001-09-10 AU AU9184901A patent/AU9184901A/xx active Pending
- 2001-09-10 WO PCT/EP2001/010442 patent/WO2002022149A1/en active IP Right Grant
-
2003
- 2003-03-06 IL IL154777A patent/IL154777A/en not_active IP Right Cessation
-
2006
- 2006-07-28 CY CY20061101058T patent/CY1105116T1/el unknown
-
2007
- 2007-01-11 US US11/622,284 patent/US20070172454A1/en not_active Abandoned
-
2010
- 2010-03-04 US US12/717,305 patent/US8329654B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IL154777A (en) | 2010-11-30 |
PT1317273E (pt) | 2006-09-29 |
AU9184901A (en) | 2002-03-26 |
AU2001291849B2 (en) | 2005-11-24 |
US20040057928A1 (en) | 2004-03-25 |
CA2419954C (en) | 2012-01-03 |
JP5030364B2 (ja) | 2012-09-19 |
US20100166703A1 (en) | 2010-07-01 |
US8329654B2 (en) | 2012-12-11 |
WO2002022149A1 (en) | 2002-03-21 |
IL154777A0 (en) | 2003-10-31 |
ES2262680T3 (es) | 2006-12-01 |
DE60119347T2 (de) | 2007-02-22 |
ATE324906T1 (de) | 2006-06-15 |
JP2004508409A (ja) | 2004-03-18 |
EP1317273B1 (en) | 2006-05-03 |
DK1317273T3 (da) | 2006-09-04 |
CA2419954A1 (en) | 2002-03-21 |
DE60119347D1 (de) | 2006-06-08 |
US20070172454A1 (en) | 2007-07-26 |
EP1317273A1 (en) | 2003-06-11 |
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