BR0316343A - Formulações pulverulentas para inalação contendo tiotrópio - Google Patents

Formulações pulverulentas para inalação contendo tiotrópio

Info

Publication number
BR0316343A
BR0316343A BR0316343-1A BR0316343A BR0316343A BR 0316343 A BR0316343 A BR 0316343A BR 0316343 A BR0316343 A BR 0316343A BR 0316343 A BR0316343 A BR 0316343A
Authority
BR
Brazil
Prior art keywords
powder formulations
inhalation powder
tiotropium
preparation
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
BR0316343-1A
Other languages
English (en)
Inventor
Mareke Hartig
Michael Trunk
Michael Walz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32308760&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0316343(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of BR0316343A publication Critical patent/BR0316343A/pt
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"FORMULAçõES PULVERULENTAS PARA INALAçãO CONTENDO TIOTRóPIO". A presente invenção refere-se a preparações pulverulentas para inalação contendo tiotrópio, a processos para sua preparação bem como ao seu uso para preparação de um medicamento para o tratamento de doenças do trato respiratório, particularmente para o tratamento de COPD ('chronic obstructive pulmonary disease' = doença pulmonar obstrutiva crónica) e asma.
BR0316343-1A 2002-11-28 2003-11-19 Formulações pulverulentas para inalação contendo tiotrópio Pending BR0316343A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10255387A DE10255387A1 (de) 2002-11-28 2002-11-28 Neue Tiotropium-haltige Pulverformulierung für die Inhalation
PCT/EP2003/012911 WO2004047796A2 (de) 2002-11-28 2003-11-19 Neue tiotropium-haltige pulverformulierung für die inhalation

Publications (1)

Publication Number Publication Date
BR0316343A true BR0316343A (pt) 2005-09-27

Family

ID=32308760

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0316343-1A Pending BR0316343A (pt) 2002-11-28 2003-11-19 Formulações pulverulentas para inalação contendo tiotrópio

Country Status (34)

Country Link
EP (1) EP1567135B1 (pt)
JP (1) JP4977321B2 (pt)
KR (1) KR101066805B1 (pt)
CN (1) CN100574751C (pt)
AR (1) AR042242A1 (pt)
AT (1) ATE401861T1 (pt)
AU (1) AU2003294714B2 (pt)
BR (1) BR0316343A (pt)
CA (1) CA2507579C (pt)
CO (1) CO5580736A2 (pt)
CY (1) CY1108420T1 (pt)
DE (2) DE10255387A1 (pt)
DK (1) DK1567135T3 (pt)
EA (1) EA011549B1 (pt)
EC (1) ECSP055821A (pt)
ES (1) ES2310681T3 (pt)
HK (1) HK1085918A1 (pt)
HR (1) HRP20050468A2 (pt)
IL (1) IL168810A (pt)
ME (1) MEP51608A (pt)
MX (1) MXPA05005485A (pt)
MY (1) MY140890A (pt)
NO (1) NO20053090L (pt)
PE (1) PE20040848A1 (pt)
PL (1) PL376229A1 (pt)
PT (1) PT1567135E (pt)
RS (1) RS20050400A (pt)
SA (1) SA04240467B1 (pt)
SI (1) SI1567135T1 (pt)
TW (1) TWI332837B (pt)
UA (1) UA81930C2 (pt)
UY (1) UY28096A1 (pt)
WO (1) WO2004047796A2 (pt)
ZA (1) ZA200502859B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102008014025A1 (de) * 2008-03-13 2009-09-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Sieb für einen Inhalator
TR200909788A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Tiotropyum içeren inhalasyona uygun kuru toz formülasyonu
CN106890165A (zh) * 2010-08-03 2017-06-27 奇斯药制品公司 包含磷酸二酯酶抑制剂的干粉制剂
BR112015010601B1 (pt) * 2012-11-09 2022-07-19 Civitas Therapeutics, Inc. Composição farmacêutica e uso da composição
KR101748796B1 (ko) * 2015-09-30 2017-06-19 한미약품 주식회사 활성성분의 전달량이 향상된 흡입용 캡슐제
KR101728116B1 (ko) * 2015-11-03 2017-04-18 한미약품 주식회사 티오트로피움 또는 이의 약학적으로 허용가능한 염을 함유하는 흡입용 건조분말 조성물
CN111514418B (zh) * 2019-06-12 2022-01-14 中南大学湘雅二医院 一种自吸式经鼻粉末材料给送装置

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242211A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
DE4140689B4 (de) * 1991-12-10 2007-11-22 Boehringer Ingelheim Kg Inhalationspulver und Verfahren zu ihrer Herstellung
DE4318455A1 (de) * 1993-06-03 1994-12-08 Boehringer Ingelheim Kg Kapselhalterung
GB9322014D0 (en) * 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
DE4425255A1 (de) * 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
PT1283036E (pt) * 1998-11-13 2008-03-06 Jagotec Ag Inalador de pó seco de dose múltipla com um reservatório de pó
GB9902689D0 (en) * 1999-02-08 1999-03-31 Novartis Ag Organic compounds
UA75375C2 (en) * 2000-10-12 2006-04-17 Boehringer Ingelheim Pharma Method for producing powdery preparations for inhaling
CN1210017C (zh) * 2000-10-12 2005-07-13 贝林格尔英格海姆法玛两合公司 含噻托品鎓的新颖可吸入粉末
DE10126924A1 (de) * 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalationskapseln
DE10141377A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Aufstreuverfahren zur Herstellung von Pulverformulierungen
DE60308497T2 (de) * 2002-04-04 2007-02-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverzubereitungen zur inhalation
UA80123C2 (en) * 2002-04-09 2007-08-27 Boehringer Ingelheim Pharma Inhalation kit comprising inhalable powder of tiotropium

Also Published As

Publication number Publication date
ES2310681T3 (es) 2009-01-16
PT1567135E (pt) 2008-09-01
MEP51608A (en) 2011-02-10
TW200500066A (en) 2005-01-01
NO20053090D0 (no) 2005-06-23
RS20050400A (en) 2007-04-10
SI1567135T1 (sl) 2008-10-31
DE50310208D1 (de) 2008-09-04
IL168810A (en) 2015-02-26
MXPA05005485A (es) 2005-07-25
DK1567135T3 (da) 2008-10-27
WO2004047796A2 (de) 2004-06-10
AU2003294714B2 (en) 2009-10-08
KR101066805B1 (ko) 2011-09-22
NO20053090L (no) 2005-06-23
CA2507579C (en) 2011-07-19
UY28096A1 (es) 2004-06-30
CY1108420T1 (el) 2014-04-09
UA81930C2 (uk) 2008-02-25
DE10255387A1 (de) 2004-06-09
AR042242A1 (es) 2005-06-15
ZA200502859B (en) 2006-02-22
ATE401861T1 (de) 2008-08-15
SA04240467B1 (ar) 2008-10-15
JP2006510622A (ja) 2006-03-30
PL376229A1 (en) 2005-12-27
EA011549B1 (ru) 2009-04-28
PE20040848A1 (es) 2005-01-14
CA2507579A1 (en) 2004-06-10
CO5580736A2 (es) 2005-11-30
ECSP055821A (es) 2005-08-11
AU2003294714A1 (en) 2004-06-18
KR20050086887A (ko) 2005-08-30
CN100574751C (zh) 2009-12-30
TWI332837B (en) 2010-11-11
HRP20050468A2 (en) 2006-07-31
EA200500864A1 (ru) 2006-02-24
CN1717225A (zh) 2006-01-04
EP1567135A2 (de) 2005-08-31
HK1085918A1 (en) 2006-09-08
EP1567135B1 (de) 2008-07-23
JP4977321B2 (ja) 2012-07-18
WO2004047796A3 (de) 2004-09-30
MY140890A (en) 2010-01-29

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI. A61K 9/72, A61K 31/46, A61P 11/00

Ipc: A61K 9/72 (2011.01), A61K 31/46 (2011.01), A61P 11

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8, 11 E 13 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.