BR0317443A - Medicamento pulverulento para inalação contendo um sal de tiotrópio e xinafoato de salmeterol - Google Patents
Medicamento pulverulento para inalação contendo um sal de tiotrópio e xinafoato de salmeterolInfo
- Publication number
- BR0317443A BR0317443A BR0317443-3A BR0317443A BR0317443A BR 0317443 A BR0317443 A BR 0317443A BR 0317443 A BR0317443 A BR 0317443A BR 0317443 A BR0317443 A BR 0317443A
- Authority
- BR
- Brazil
- Prior art keywords
- salmeterol xinafoate
- powder containing
- tiotropium salt
- inhalation powder
- containing tiotropium
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"MEDICAMENTO PULVERULENTO PARA INALAçãO CONTENDO UM SAL DE TIOTRóPIO E XINAFOATO DE SALMETEROL". A presente invenção refere-se a preparações pulverulentas para inalação contendo um sal de tiotrópio e xinafoato de salmeterol, processos para sua preparação bem como ao seu uso para preparação de um medicamento para o tratamento de doenças do trato respiratório, particularmente para o tratamento de COPD (chronic obstructive pulmonary disease = doença pulmonar obstrutiva crónica) e asma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10259912 | 2002-12-20 | ||
PCT/EP2003/013691 WO2004058233A1 (de) | 2002-12-20 | 2003-12-04 | Pulverförmige arzneimittel zur inhalation enthaltend ein tiotropiumsalz und salmeterolxinafoat |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0317443A true BR0317443A (pt) | 2005-11-16 |
Family
ID=32404034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0317443-3A BR0317443A (pt) | 2002-12-20 | 2003-12-04 | Medicamento pulverulento para inalação contendo um sal de tiotrópio e xinafoato de salmeterol |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1581198A1 (pt) |
JP (1) | JP2006516135A (pt) |
KR (1) | KR20050086930A (pt) |
CN (1) | CN1728988B (pt) |
AU (1) | AU2003288226B2 (pt) |
BR (1) | BR0317443A (pt) |
CA (1) | CA2510779A1 (pt) |
DE (1) | DE10351663A1 (pt) |
EA (1) | EA010588B1 (pt) |
EC (1) | ECSP055855A (pt) |
FR (1) | FR2848849B1 (pt) |
HR (1) | HRP20050570A2 (pt) |
IT (1) | ITMI20032473A1 (pt) |
MX (1) | MXPA05006519A (pt) |
NO (1) | NO20053548L (pt) |
NZ (1) | NZ541303A (pt) |
PL (1) | PL376231A1 (pt) |
RS (1) | RS20050484A (pt) |
UA (1) | UA83813C2 (pt) |
WO (1) | WO2004058233A1 (pt) |
ZA (1) | ZA200503692B (pt) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
JP4342426B2 (ja) * | 2004-11-24 | 2009-10-14 | 科研製薬株式会社 | イトラコナゾール経口投与用製剤 |
CA2617897A1 (en) * | 2005-08-06 | 2007-02-15 | Boehringer Ingelheim International Gmbh | Method for the treatment of dyspnea comprising combined administration of tiotropium salts and salts of salmeterol |
JP5086267B2 (ja) | 2005-12-19 | 2012-11-28 | シコール インコーポレイティド | 臭化チオトロピウムの新規な形態およびそれを製造する方法 |
PE20110235A1 (es) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
CA2810839A1 (en) | 2006-05-04 | 2007-11-15 | Boehringer Ingelheim International Gmbh | A polymorphic form of 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(r)-amino-piperidin-1-yl)-xanthine |
EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
DE102007036411A1 (de) | 2007-07-20 | 2009-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
UY31235A1 (es) * | 2007-07-21 | 2009-03-02 | Nuevos medicamentos pulverulentos que contienen tiotropio y salmeterol, asi como lactosa como excipiente | |
PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
KR20200118243A (ko) | 2008-08-06 | 2020-10-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
AU2009331471B2 (en) | 2008-12-23 | 2015-09-03 | Boehringer Ingelheim International Gmbh | Salt forms of organic compound |
TW201036975A (en) | 2009-01-07 | 2010-10-16 | Boehringer Ingelheim Int | Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy |
KR20240090632A (ko) | 2009-11-27 | 2024-06-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료 |
CN102946875A (zh) | 2010-05-05 | 2013-02-27 | 贝林格尔.英格海姆国际有限公司 | 组合疗法 |
CA2803504C (en) | 2010-06-24 | 2022-08-30 | Boehringer Ingelheim International Gmbh | A combination for diabetes therapy comprising linagliptin and a long-acting insulin |
US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
DK2731947T3 (en) | 2011-07-15 | 2019-04-23 | Boehringer Ingelheim Int | SUBSTITUTED DIMERIC QUINAZOLINE DERIVATIVE, PREPARATION AND USE thereof IN PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF TYPE I AND TYPE II DIABETES |
US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
EP2849755A1 (en) | 2012-05-14 | 2015-03-25 | Boehringer Ingelheim International GmbH | A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome |
WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
JP6615109B2 (ja) | 2014-02-28 | 2019-12-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Dpp−4阻害薬の医学的使用 |
KR101748796B1 (ko) * | 2015-09-30 | 2017-06-19 | 한미약품 주식회사 | 활성성분의 전달량이 향상된 흡입용 캡슐제 |
WO2017211979A1 (en) | 2016-06-10 | 2017-12-14 | Boehringer Ingelheim International Gmbh | Combinations of linagliptin and metformin |
EA202191327A1 (ru) * | 2018-11-13 | 2021-08-09 | Кокристал Фарма, Инк. | Лекарственные формы терапевтических препаратов от гриппа |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1056974C (zh) * | 1992-02-11 | 2000-10-04 | 格拉克索公司 | 适宜于微粒化的药物材料的制备方法 |
AU1229892A (en) * | 1992-02-11 | 1993-09-03 | Glaxo Group Limited | Benzenedimethanol derivative suitable for micronisation |
GB9313650D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
UA75375C2 (en) * | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
DE10056104A1 (de) * | 2000-11-13 | 2002-05-23 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Tiotropiumsalzen und Salzen des Salmeterols |
DE10104367A1 (de) * | 2001-02-01 | 2002-08-08 | Boehringer Ingelheim Pharma | Betamimetika enthaltende Arzneimittelkompositionen mit geringeren Nebenwirkungen |
DE10130371A1 (de) * | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika |
WO2003013633A1 (en) * | 2001-08-09 | 2003-02-20 | Glaxo Group Limited | Inhalation device with a pharmaceutical composition |
JP2005504076A (ja) * | 2001-09-14 | 2005-02-10 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 新規な吸入用医薬組成物 |
-
2003
- 2003-11-05 DE DE10351663A patent/DE10351663A1/de not_active Withdrawn
- 2003-12-04 BR BR0317443-3A patent/BR0317443A/pt not_active IP Right Cessation
- 2003-12-04 JP JP2004562686A patent/JP2006516135A/ja active Pending
- 2003-12-04 PL PL03376231A patent/PL376231A1/xx not_active Application Discontinuation
- 2003-12-04 MX MXPA05006519A patent/MXPA05006519A/es unknown
- 2003-12-04 UA UAA200507088A patent/UA83813C2/ru unknown
- 2003-12-04 CA CA002510779A patent/CA2510779A1/en not_active Abandoned
- 2003-12-04 EP EP03780120A patent/EP1581198A1/de not_active Withdrawn
- 2003-12-04 KR KR1020057011668A patent/KR20050086930A/ko not_active Application Discontinuation
- 2003-12-04 CN CN2003801069216A patent/CN1728988B/zh not_active Expired - Fee Related
- 2003-12-04 RS YUP-2005/0484A patent/RS20050484A/sr unknown
- 2003-12-04 EA EA200500902A patent/EA010588B1/ru not_active IP Right Cessation
- 2003-12-04 AU AU2003288226A patent/AU2003288226B2/en not_active Ceased
- 2003-12-04 NZ NZ541303A patent/NZ541303A/en unknown
- 2003-12-04 WO PCT/EP2003/013691 patent/WO2004058233A1/de active Application Filing
- 2003-12-16 IT IT002473A patent/ITMI20032473A1/it unknown
- 2003-12-19 FR FR0315082A patent/FR2848849B1/fr not_active Expired - Fee Related
-
2005
- 2005-05-09 ZA ZA200503692A patent/ZA200503692B/en unknown
- 2005-06-15 EC EC2005005855A patent/ECSP055855A/es unknown
- 2005-06-17 HR HR20050570A patent/HRP20050570A2/xx not_active Application Discontinuation
- 2005-07-19 NO NO20053548A patent/NO20053548L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NZ541303A (en) | 2008-11-28 |
ITMI20032473A1 (it) | 2004-06-21 |
FR2848849A1 (fr) | 2004-06-25 |
EP1581198A1 (de) | 2005-10-05 |
NO20053548L (no) | 2005-09-02 |
CA2510779A1 (en) | 2004-07-15 |
HRP20050570A2 (en) | 2006-07-31 |
CN1728988B (zh) | 2010-04-28 |
EA200500902A1 (ru) | 2006-02-24 |
PL376231A1 (en) | 2005-12-27 |
CN1728988A (zh) | 2006-02-01 |
ECSP055855A (es) | 2005-11-22 |
WO2004058233A1 (de) | 2004-07-15 |
DE10351663A1 (de) | 2004-07-01 |
ZA200503692B (en) | 2006-10-25 |
JP2006516135A (ja) | 2006-06-22 |
KR20050086930A (ko) | 2005-08-30 |
UA83813C2 (ru) | 2008-08-26 |
AU2003288226B2 (en) | 2010-01-07 |
MXPA05006519A (es) | 2005-08-26 |
AU2003288226A1 (en) | 2004-07-22 |
RS20050484A (en) | 2007-11-15 |
EA010588B1 (ru) | 2008-10-30 |
FR2848849B1 (fr) | 2007-01-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012. |