RS20050484A - Lek, u obliku praha za inhalaciju, koji sadrži so tiotropijuma i salmeterolksinafoat - Google Patents
Lek, u obliku praha za inhalaciju, koji sadrži so tiotropijuma i salmeterolksinafoatInfo
- Publication number
- RS20050484A RS20050484A YUP-2005/0484A YUP20050484A RS20050484A RS 20050484 A RS20050484 A RS 20050484A YU P20050484 A YUP20050484 A YU P20050484A RS 20050484 A RS20050484 A RS 20050484A
- Authority
- RS
- Serbia
- Prior art keywords
- inhalation
- salmeterol xinafoate
- tiotropium salt
- powdered medicament
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Pronalazak se odnosi na preparate u obliku praha za inhaliranje, koji sadrže so tiotropijuma i salmeterolksinafoat, na postupak za njihovo pripremanje kao i na njihovu primenu za pripremanje leka za lečenje oboljenja disajnih puteva, naročito za tretiranje COPD-a (chronic obstructive pulmonary disease = hronično opstruktivno oboljenje pluća) i astme.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10259912 | 2002-12-20 | ||
| PCT/EP2003/013691 WO2004058233A1 (de) | 2002-12-20 | 2003-12-04 | Pulverförmige arzneimittel zur inhalation enthaltend ein tiotropiumsalz und salmeterolxinafoat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS20050484A true RS20050484A (sr) | 2007-11-15 |
Family
ID=32404034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YUP-2005/0484A RS20050484A (sr) | 2002-12-20 | 2003-12-04 | Lek, u obliku praha za inhalaciju, koji sadrži so tiotropijuma i salmeterolksinafoat |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1581198A1 (sr) |
| JP (1) | JP2006516135A (sr) |
| KR (1) | KR20050086930A (sr) |
| CN (1) | CN1728988B (sr) |
| AU (1) | AU2003288226B2 (sr) |
| BR (1) | BR0317443A (sr) |
| CA (1) | CA2510779A1 (sr) |
| DE (1) | DE10351663A1 (sr) |
| EA (1) | EA010588B1 (sr) |
| EC (1) | ECSP055855A (sr) |
| FR (1) | FR2848849B1 (sr) |
| HR (1) | HRP20050570A2 (sr) |
| IT (1) | ITMI20032473A1 (sr) |
| MX (1) | MXPA05006519A (sr) |
| NO (1) | NO20053548L (sr) |
| NZ (1) | NZ541303A (sr) |
| PL (1) | PL376231A1 (sr) |
| RS (1) | RS20050484A (sr) |
| UA (1) | UA83813C2 (sr) |
| WO (1) | WO2004058233A1 (sr) |
| ZA (1) | ZA200503692B (sr) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| JP4342426B2 (ja) * | 2004-11-24 | 2009-10-14 | 科研製薬株式会社 | イトラコナゾール経口投与用製剤 |
| EP1959942A1 (en) * | 2005-08-06 | 2008-08-27 | Boehringer Ingelheim International GmbH | Method for the treatment of dyspnea comprising combined administration of tiotropium salts and salts of salmeterol |
| CN102731494A (zh) * | 2005-12-19 | 2012-10-17 | 西科尔公司 | 噻托溴铵的新形式及其制备方法 |
| BRPI0711558A2 (pt) | 2006-05-04 | 2011-11-08 | Boeringer Ingelheim Internat Gmbh | polimorfos |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| DE102007036411A1 (de) * | 2007-07-20 | 2009-02-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
| PE20090907A1 (es) * | 2007-07-21 | 2009-08-05 | Boehringer Ingelheim Int | Nuevos medicamentos pulverulentos que contienen tiotropio y salmeterol, asi como lactosa como excipiente |
| PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| KR20190016601A (ko) | 2008-08-06 | 2019-02-18 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
| UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| NZ592924A (en) | 2008-12-23 | 2014-05-30 | Boehringer Ingelheim Int | Salt forms of a xanthine derivative |
| AR074990A1 (es) | 2009-01-07 | 2011-03-02 | Boehringer Ingelheim Int | Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina |
| KR20240090632A (ko) | 2009-11-27 | 2024-06-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료 |
| US9186392B2 (en) | 2010-05-05 | 2015-11-17 | Boehringer Ingelheim International Gmbh | Combination therapy |
| EP3725325B1 (en) | 2010-06-24 | 2023-05-31 | Boehringer Ingelheim International GmbH | Diabetes therapy |
| US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
| CN103781788B (zh) | 2011-07-15 | 2016-08-17 | 勃林格殷格翰国际有限公司 | 经取代的喹唑啉、其制备及其在药物组合物中的用途 |
| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| ES2929025T3 (es) | 2012-05-14 | 2022-11-24 | Boehringer Ingelheim Int | Linagliptina, un derivado de xantina como inhibidor de dpp-4, para su uso en el tratamiento del SRIS y/o de la septicemia |
| EP2849755A1 (en) | 2012-05-14 | 2015-03-25 | Boehringer Ingelheim International GmbH | A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome |
| WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
| JP6615109B2 (ja) | 2014-02-28 | 2019-12-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Dpp−4阻害薬の医学的使用 |
| KR101748796B1 (ko) * | 2015-09-30 | 2017-06-19 | 한미약품 주식회사 | 활성성분의 전달량이 향상된 흡입용 캡슐제 |
| KR102391564B1 (ko) | 2016-06-10 | 2022-04-29 | 베링거 인겔하임 인터내셔날 게엠베하 | 리나글립틴 및 메트포르민의 병용물 |
| CA3119145A1 (en) | 2018-11-13 | 2020-05-22 | Cocrystal Pharma, Inc. | Formulations comprising 3-(2-(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoro-7h-pyrrolo[2,3-d]pyrimid-7-yl)bicyclo[2.2.2]octane-2-carboxylic acid for the treatment of influenza |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1056974C (zh) * | 1992-02-11 | 2000-10-04 | 格拉克索公司 | 适宜于微粒化的药物材料的制备方法 |
| AU1229892A (en) * | 1992-02-11 | 1993-09-03 | Glaxo Group Limited | Benzenedimethanol derivative suitable for micronisation |
| GB9313650D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
| UA75375C2 (en) * | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
| DE10056104A1 (de) * | 2000-11-13 | 2002-05-23 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Tiotropiumsalzen und Salzen des Salmeterols |
| DE10104367A1 (de) * | 2001-02-01 | 2002-08-08 | Boehringer Ingelheim Pharma | Betamimetika enthaltende Arzneimittelkompositionen mit geringeren Nebenwirkungen |
| DE10130371A1 (de) * | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika |
| EP1416990A1 (en) * | 2001-08-09 | 2004-05-12 | Glaxo Group Limited | Inhalation device with a pharmaceutical composition |
| WO2003024452A1 (de) * | 2001-09-14 | 2003-03-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue arzneimittel zur inhalation |
-
2003
- 2003-04-12 UA UAA200507088A patent/UA83813C2/ru unknown
- 2003-11-05 DE DE10351663A patent/DE10351663A1/de not_active Withdrawn
- 2003-12-04 RS YUP-2005/0484A patent/RS20050484A/sr unknown
- 2003-12-04 AU AU2003288226A patent/AU2003288226B2/en not_active Ceased
- 2003-12-04 WO PCT/EP2003/013691 patent/WO2004058233A1/de active Application Filing
- 2003-12-04 CN CN2003801069216A patent/CN1728988B/zh not_active Expired - Fee Related
- 2003-12-04 MX MXPA05006519A patent/MXPA05006519A/es unknown
- 2003-12-04 EP EP03780120A patent/EP1581198A1/de not_active Withdrawn
- 2003-12-04 BR BR0317443-3A patent/BR0317443A/pt not_active IP Right Cessation
- 2003-12-04 JP JP2004562686A patent/JP2006516135A/ja active Pending
- 2003-12-04 CA CA002510779A patent/CA2510779A1/en not_active Abandoned
- 2003-12-04 PL PL03376231A patent/PL376231A1/xx not_active Application Discontinuation
- 2003-12-04 KR KR1020057011668A patent/KR20050086930A/ko not_active Ceased
- 2003-12-04 HR HR20050570A patent/HRP20050570A2/xx not_active Application Discontinuation
- 2003-12-04 EA EA200500902A patent/EA010588B1/ru not_active IP Right Cessation
- 2003-12-04 NZ NZ541303A patent/NZ541303A/en unknown
- 2003-12-16 IT IT002473A patent/ITMI20032473A1/it unknown
- 2003-12-19 FR FR0315082A patent/FR2848849B1/fr not_active Expired - Fee Related
-
2005
- 2005-05-09 ZA ZA200503692A patent/ZA200503692B/en unknown
- 2005-06-15 EC EC2005005855A patent/ECSP055855A/es unknown
- 2005-07-19 NO NO20053548A patent/NO20053548L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1728988A (zh) | 2006-02-01 |
| EA200500902A1 (ru) | 2006-02-24 |
| ITMI20032473A1 (it) | 2004-06-21 |
| ECSP055855A (es) | 2005-11-22 |
| JP2006516135A (ja) | 2006-06-22 |
| ZA200503692B (en) | 2006-10-25 |
| FR2848849A1 (fr) | 2004-06-25 |
| AU2003288226A1 (en) | 2004-07-22 |
| MXPA05006519A (es) | 2005-08-26 |
| WO2004058233A1 (de) | 2004-07-15 |
| BR0317443A (pt) | 2005-11-16 |
| HRP20050570A2 (en) | 2006-07-31 |
| EA010588B1 (ru) | 2008-10-30 |
| CA2510779A1 (en) | 2004-07-15 |
| NO20053548L (no) | 2005-09-02 |
| PL376231A1 (en) | 2005-12-27 |
| AU2003288226B2 (en) | 2010-01-07 |
| CN1728988B (zh) | 2010-04-28 |
| FR2848849B1 (fr) | 2007-01-05 |
| UA83813C2 (ru) | 2008-08-26 |
| KR20050086930A (ko) | 2005-08-30 |
| NZ541303A (en) | 2008-11-28 |
| EP1581198A1 (de) | 2005-10-05 |
| DE10351663A1 (de) | 2004-07-01 |
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