CY1114157T1 - Αλατα του τιοτροπιου, μεθοδος για την παραγωγη τους και φαρμακευτικα σκευασματα που τα περιεχουν - Google Patents

Αλατα του τιοτροπιου, μεθοδος για την παραγωγη τους και φαρμακευτικα σκευασματα που τα περιεχουν

Info

Publication number
CY1114157T1
CY1114157T1 CY20131100607T CY131100607T CY1114157T1 CY 1114157 T1 CY1114157 T1 CY 1114157T1 CY 20131100607 T CY20131100607 T CY 20131100607T CY 131100607 T CY131100607 T CY 131100607T CY 1114157 T1 CY1114157 T1 CY 1114157T1
Authority
CY
Cyprus
Prior art keywords
production
silver
types
pharmaceutical containers
treatment
Prior art date
Application number
CY20131100607T
Other languages
English (en)
Inventor
Rolf Banholzer
Peter Sieger
Waldemar Pfrengle
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34530660&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1114157(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of CY1114157T1 publication Critical patent/CY1114157T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms

Abstract

Η εφεύρεση αφορά μια μέθοδο για την παραγωγή νέων αλάτων του τιοτροπίου, αυτά τα νέα άλατα του τιοτροπίου ως τέτοια, φαρμακευτικά σκευάσματα που τα περιέχουν, καθώς και τη χρήση τους για την παραγωγή ενός φαρμάκου για τη θεραπεία παθήσεων των αναπνευστικών οδών, ιδιαιτέρως για τη θεραπεία της ΧΑΠ (COPD = chronic obstructive pulmonary disease = χρόνιας αποφρακτικής πνευμονοπάθειας) και του άσθματος.
CY20131100607T 2003-11-03 2013-07-17 Αλατα του τιοτροπιου, μεθοδος για την παραγωγη τους και φαρμακευτικα σκευασματα που τα περιεχουν CY1114157T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03025075 2003-11-03
EP09153379.4A EP2067779B9 (de) 2003-11-03 2004-10-29 Tiotropiumsalze, Verfahren zu deren Herstellung und Arzneimittelformulierungen diese enthaltend

Publications (1)

Publication Number Publication Date
CY1114157T1 true CY1114157T1 (el) 2016-08-31

Family

ID=34530660

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20101100435T CY1110048T1 (el) 2003-11-03 2010-05-17 Μεθοδος για την παραγωγη αλατων του τιοτροπιου
CY20131100607T CY1114157T1 (el) 2003-11-03 2013-07-17 Αλατα του τιοτροπιου, μεθοδος για την παραγωγη τους και φαρμακευτικα σκευασματα που τα περιεχουν

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20101100435T CY1110048T1 (el) 2003-11-03 2010-05-17 Μεθοδος για την παραγωγη αλατων του τιοτροπιου

Country Status (35)

Country Link
US (1) US8686148B2 (el)
EP (3) EP1682541B1 (el)
JP (1) JP5165244B2 (el)
KR (1) KR20060117334A (el)
CN (3) CN101407514B (el)
AR (1) AR046317A1 (el)
AT (1) ATE460414T1 (el)
AU (1) AU2004285683C1 (el)
BR (1) BRPI0416136A (el)
CA (1) CA2544348A1 (el)
CO (1) CO5690553A2 (el)
CY (2) CY1110048T1 (el)
DE (1) DE502004010885D1 (el)
DK (2) DK2067779T3 (el)
EA (1) EA012326B1 (el)
ES (2) ES2422729T3 (el)
HK (3) HK1129111A1 (el)
HR (1) HRP20100149T1 (el)
IL (1) IL175023A (el)
ME (1) ME00361B (el)
MX (1) MXPA06004697A (el)
MY (1) MY143364A (el)
NO (1) NO335814B1 (el)
NZ (1) NZ547276A (el)
PE (1) PE20050446A1 (el)
PL (2) PL2067779T3 (el)
PT (2) PT1682541E (el)
RS (2) RS51758B (el)
SG (1) SG137859A1 (el)
SI (2) SI1682541T1 (el)
TW (2) TWI435876B (el)
UA (1) UA82413C2 (el)
UY (1) UY28590A1 (el)
WO (1) WO2005042526A1 (el)
ZA (1) ZA200602342B (el)

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US20060079544A1 (en) * 2004-08-13 2006-04-13 Boehringer Ingelheim International Gmbh Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
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EP2123650B1 (en) 2005-12-19 2012-04-04 Sicor, Inc. Novel form of tiotropium bromide and process for preparation thereof
CA2634984C (en) * 2006-01-04 2014-05-06 Boehringer Ingelheim International Gmbh Use of tiotropium salts in the treatment of moderate persistent asthma
EP1953156A1 (de) * 2007-01-29 2008-08-06 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung von Scopiniumsalzen
CZ201241A3 (cs) 2012-01-20 2013-07-31 Zentiva, K.S. Nové polymorfní formy tiotropium jodidu a zpusob jejich prípravy
WO2014042605A1 (en) * 2012-09-11 2014-03-20 Mahmut Bilgic New tiotropium bromide crystalline form
JP6042197B2 (ja) * 2012-12-11 2016-12-14 エア・ウォーター株式会社 肺障害治療剤

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Also Published As

Publication number Publication date
RS20060292A (en) 2008-08-07
UA82413C2 (uk) 2008-04-10
TWI363758B (en) 2012-05-11
NO335814B1 (no) 2015-02-23
US8686148B2 (en) 2014-04-01
CN102070630B (zh) 2013-04-17
CN102070630A (zh) 2011-05-25
ES2422729T3 (es) 2013-09-13
HRP20100149T1 (hr) 2010-04-30
SI1682541T1 (sl) 2010-06-30
HK1129111A1 (en) 2009-11-20
EP2067779B1 (de) 2013-04-24
PT1682541E (pt) 2010-04-14
ME00361B (me) 2011-10-10
EP2067779B9 (de) 2013-10-16
EA200600886A1 (ru) 2006-10-27
CN101407514A (zh) 2009-04-15
MY143364A (en) 2011-04-29
PE20050446A1 (es) 2005-08-02
EP1682541B1 (de) 2010-03-10
ZA200602342B (en) 2007-06-27
DK1682541T3 (da) 2010-06-28
EA012326B1 (ru) 2009-08-28
SI2067779T1 (sl) 2013-08-30
HK1153409A1 (en) 2012-03-30
RS51758B (en) 2011-12-31
MXPA06004697A (es) 2006-07-05
NO20061440L (no) 2006-07-12
PL1682541T3 (pl) 2010-08-31
UY28590A1 (es) 2005-06-30
KR20060117334A (ko) 2006-11-16
AU2004285683B2 (en) 2011-04-21
AR046317A1 (es) 2005-11-30
IL175023A (en) 2011-02-28
CN1882582A (zh) 2006-12-20
EP1682541A1 (de) 2006-07-26
WO2005042526A1 (de) 2005-05-12
AU2004285683A1 (en) 2005-05-12
PL2067779T3 (pl) 2013-09-30
JP5165244B2 (ja) 2013-03-21
BRPI0416136A (pt) 2007-01-02
MEP51308A (en) 2011-05-10
IL175023A0 (en) 2006-08-20
NZ547276A (en) 2009-08-28
SG137859A1 (en) 2007-12-28
CO5690553A2 (es) 2006-10-31
HK1099748A1 (en) 2007-08-24
EP2067779A1 (de) 2009-06-10
US20050131007A1 (en) 2005-06-16
TW200526653A (en) 2005-08-16
CY1110048T1 (el) 2015-01-14
JP2007509893A (ja) 2007-04-19
CN100549010C (zh) 2009-10-14
EP2336126A1 (de) 2011-06-22
TW201231465A (en) 2012-08-01
ES2342468T3 (es) 2010-07-07
CA2544348A1 (en) 2005-05-12
AU2004285683C1 (en) 2011-09-08
PT2067779E (pt) 2013-07-25
DE502004010885D1 (de) 2010-04-22
CN101407514B (zh) 2013-05-29
TWI435876B (zh) 2014-05-01
DK2067779T3 (da) 2013-07-29
ATE460414T1 (de) 2010-03-15

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