PE20040570A1 - Tiadiazoldioxidos y tiadiazoloxidos como ligandos del receptor de cxc- y cc-quimiocina - Google Patents
Tiadiazoldioxidos y tiadiazoloxidos como ligandos del receptor de cxc- y cc-quimiocinaInfo
- Publication number
- PE20040570A1 PE20040570A1 PE2003001019A PE2003001019A PE20040570A1 PE 20040570 A1 PE20040570 A1 PE 20040570A1 PE 2003001019 A PE2003001019 A PE 2003001019A PE 2003001019 A PE2003001019 A PE 2003001019A PE 20040570 A1 PE20040570 A1 PE 20040570A1
- Authority
- PE
- Peru
- Prior art keywords
- alkyl
- substituted
- halogen
- heteroaryl
- ring
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41737102P | 2002-10-09 | 2002-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20040570A1 true PE20040570A1 (es) | 2004-08-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2003001019A PE20040570A1 (es) | 2002-10-09 | 2003-10-07 | Tiadiazoldioxidos y tiadiazoloxidos como ligandos del receptor de cxc- y cc-quimiocina |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20040186142A1 (enExample) |
| EP (1) | EP1551818B1 (enExample) |
| JP (2) | JP4664074B2 (enExample) |
| CN (1) | CN1720240B (enExample) |
| AR (1) | AR043052A1 (enExample) |
| AT (1) | ATE422203T1 (enExample) |
| AU (1) | AU2003288922A1 (enExample) |
| CA (1) | CA2501535A1 (enExample) |
| DE (1) | DE60326080D1 (enExample) |
| ES (1) | ES2321186T3 (enExample) |
| MX (1) | MXPA05003867A (enExample) |
| MY (1) | MY139601A (enExample) |
| PE (1) | PE20040570A1 (enExample) |
| TW (1) | TW200413342A (enExample) |
| WO (1) | WO2004033440A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040106794A1 (en) * | 2001-04-16 | 2004-06-03 | Schering Corporation | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
| NZ535314A (en) * | 2002-03-18 | 2007-08-31 | Schering Corp | Combination treatments for chemokine-mediated diseases |
| ES2321186T3 (es) * | 2002-10-09 | 2009-06-03 | Schering Corporation | Dioxidos de tiadiazol y monoxidos de tiadiazol como ligandos de los receptores de quimioquinas cxc y cc. |
| US20060004088A1 (en) * | 2002-10-22 | 2006-01-05 | Oct Inc. | Furan derivatives for preventing and curing osteoporosis and pharmaceutical compositions containing the same |
| AR047759A1 (es) * | 2003-09-26 | 2006-02-22 | Vertex Pharma | Derivados de fenil - piperazina como moduladores de receptores muscarnicos |
| MY139808A (en) | 2003-12-19 | 2009-10-30 | Schering Corp | Thiadiazoles as cxc-and cc-chemokine receptor ligands |
| JP4851943B2 (ja) * | 2003-12-22 | 2012-01-11 | シェーリング コーポレイション | Cxc−ケモカインレセプターリガンドおよびcc−ケモカインレセプターリガンドとしてのイソチアゾールジオキシド |
| KR20070011475A (ko) | 2004-05-12 | 2007-01-24 | 쉐링 코포레이션 | Cxcr1 및 cxcr2 케모카인 길항제 |
| PE20060272A1 (es) * | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
| WO2005118609A2 (en) * | 2004-05-26 | 2005-12-15 | California Institute Of Technology | Small molecule stimulators of neuronal growth |
| WO2006012226A2 (en) | 2004-06-24 | 2006-02-02 | Incyte Corporation | N-substituted piperidines and their use as pharmaceuticals |
| GB0510140D0 (en) | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B2 |
| ATE486078T1 (de) * | 2005-06-29 | 2010-11-15 | Schering Corp | 5,6-disubstituierte oxadiazolopyrazine und thiadiazolopyrazine als liganden des cxc- chemokinrezeptors |
| CN101253165A (zh) * | 2005-06-29 | 2008-08-27 | 先灵公司 | 作为cxc-化学活素受体配体的二取代的二唑 |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| RU2009103999A (ru) * | 2006-07-07 | 2010-08-20 | Шеринг Корпорейшн (US) | 3,4-дизамещенные циклобутен-1,2-дионы как лиганды схс-хемокиновых рецепторов |
| EP2351743A4 (en) * | 2008-10-27 | 2012-05-09 | Takeda Pharmaceutical | BICYCLIC COMPOUND |
| ES2603032T3 (es) | 2010-07-15 | 2017-02-23 | Bayer Intellectual Property Gmbh | Compuestos de 3-piridil-heteroarilcarboxamida como pesticidas |
| WO2012148547A1 (en) * | 2011-02-24 | 2012-11-01 | The Schepens Eye Research Institute, Inc. | Compositions and methods for treating inflammatory conditions of the ocular surface |
| US8865723B2 (en) | 2012-10-25 | 2014-10-21 | Tetra Discovery Partners Llc | Selective PDE4 B inhibition and improvement in cognition in subjects with brain injury |
| US9770461B2 (en) | 2013-08-02 | 2017-09-26 | California Institute Of Technology | Tailored glycopolymers as anticoagulant heparin mimetics |
| US10227370B2 (en) | 2013-08-02 | 2019-03-12 | California Institute Of Technology | Heparan sulfate/heparin mimetics with anti-chemokine and anti-inflammatory activity |
| CN103724304B (zh) * | 2013-12-24 | 2016-08-17 | 定陶县友帮化工有限公司 | 5-溴苯并呋喃的制备方法 |
| CN103787956B (zh) * | 2014-01-20 | 2016-03-30 | 上海医药工业研究院 | 用于制备泊马度胺的中间体的制备方法 |
| US9763992B2 (en) | 2014-02-13 | 2017-09-19 | Father Flanagan's Boys' Home | Treatment of noise induced hearing loss |
| WO2018073248A1 (en) | 2016-10-17 | 2018-04-26 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Prognosis of demyelinating diseases patients and treatment thereof |
| EP3551034A1 (en) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018112264A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| US11066488B2 (en) | 2017-06-20 | 2021-07-20 | Dow Global Technologies Llc | Biaryl phenoxy group IV transition metal catalysts for olefin polymerization |
| CN116874466A (zh) * | 2018-09-21 | 2023-10-13 | 辉瑞公司 | 用作ccr6抑制剂的n-取代二氧代环丁烯基氨基-3-羟基-吡啶甲酰胺 |
| AU2019383976B2 (en) | 2018-11-19 | 2025-07-03 | Bt Bidco, Inc. | Methods and devices for treating a disease with biotherapeutics |
| CN109970588B (zh) * | 2019-03-14 | 2024-03-08 | 武汉南望环保技术研究有限责任公司 | 一种无毒耐久型防污涂料及其制备方法 |
| US11707610B2 (en) | 2019-12-13 | 2023-07-25 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| BG67727B1 (bg) | 2022-04-04 | 2025-05-15 | "Мицар Иновейшън" ООД | Пан-хемокинови антагонисти за използване при превенция и намаляване на метастази при рак |
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-
2003
- 2003-10-07 ES ES03781311T patent/ES2321186T3/es not_active Expired - Lifetime
- 2003-10-07 AT AT03781311T patent/ATE422203T1/de not_active IP Right Cessation
- 2003-10-07 WO PCT/US2003/031707 patent/WO2004033440A1/en not_active Ceased
- 2003-10-07 US US10/680,393 patent/US20040186142A1/en not_active Abandoned
- 2003-10-07 MX MXPA05003867A patent/MXPA05003867A/es not_active Application Discontinuation
- 2003-10-07 JP JP2004543449A patent/JP4664074B2/ja not_active Expired - Fee Related
- 2003-10-07 CA CA002501535A patent/CA2501535A1/en not_active Abandoned
- 2003-10-07 EP EP03781311A patent/EP1551818B1/en not_active Expired - Lifetime
- 2003-10-07 CN CN2003801051392A patent/CN1720240B/zh not_active Expired - Fee Related
- 2003-10-07 PE PE2003001019A patent/PE20040570A1/es not_active Application Discontinuation
- 2003-10-07 AU AU2003288922A patent/AU2003288922A1/en not_active Abandoned
- 2003-10-07 MY MYPI20033827A patent/MY139601A/en unknown
- 2003-10-07 DE DE60326080T patent/DE60326080D1/de not_active Expired - Lifetime
- 2003-10-08 AR ARP030103663A patent/AR043052A1/es unknown
- 2003-10-08 TW TW092127957A patent/TW200413342A/zh unknown
-
2007
- 2007-01-09 US US11/651,128 patent/US7691856B2/en not_active Expired - Fee Related
-
2010
- 2010-09-02 JP JP2010197184A patent/JP2010270151A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1551818A1 (en) | 2005-07-13 |
| EP1551818B1 (en) | 2009-02-04 |
| CA2501535A1 (en) | 2004-04-22 |
| JP2006508079A (ja) | 2006-03-09 |
| AU2003288922A1 (en) | 2004-05-04 |
| ES2321186T3 (es) | 2009-06-03 |
| CN1720240A (zh) | 2006-01-11 |
| WO2004033440A1 (en) | 2004-04-22 |
| WO2004033440A8 (en) | 2005-06-02 |
| JP2010270151A (ja) | 2010-12-02 |
| TW200413342A (en) | 2004-08-01 |
| CN1720240B (zh) | 2010-10-27 |
| MY139601A (en) | 2009-10-30 |
| JP4664074B2 (ja) | 2011-04-06 |
| MXPA05003867A (es) | 2005-11-23 |
| US20070264230A1 (en) | 2007-11-15 |
| US7691856B2 (en) | 2010-04-06 |
| AR043052A1 (es) | 2005-07-13 |
| US20040186142A1 (en) | 2004-09-23 |
| DE60326080D1 (en) | 2009-03-19 |
| ATE422203T1 (de) | 2009-02-15 |
| HK1072432A1 (en) | 2005-10-28 |
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