PE20031014A1 - Metodo para producir l-aminoacido - Google Patents

Metodo para producir l-aminoacido

Info

Publication number
PE20031014A1
PE20031014A1 PE2003000298A PE2003000298A PE20031014A1 PE 20031014 A1 PE20031014 A1 PE 20031014A1 PE 2003000298 A PE2003000298 A PE 2003000298A PE 2003000298 A PE2003000298 A PE 2003000298A PE 20031014 A1 PE20031014 A1 PE 20031014A1
Authority
PE
Peru
Prior art keywords
amino acid
produce
medium
microorganism
phosphogluconate
Prior art date
Application number
PE2003000298A
Other languages
English (en)
Inventor
Hiroshi Izui
Takahiro Asano
Yasuyuki Watanabe
Tsuyoshi Nakamatsu
Yoshihiko Hara
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of PE20031014A1 publication Critical patent/PE20031014A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

QUE COMPRENDE: 1)CULTIVAR UN MICROORGANISMO TENIENDO LA CAPACIDAD DE PRODUCIR UN L-AMINOACIDO EN UN MEDIO PARA PRODUCIR Y ACUMULAR EL L-AMINOACIDO; Y, 2)RECOLECTAR EL L-AMINOACIDO DESDE EL MEDIO; DONDE, EL MICROORGANISNO ES UNA BACTERIA GRAMNEGATIVA, QUE TIENE LA VIA ENTNER-DOUDOROFF Y QUE HA SIDO MODIFICADA DE MODO QUE LA ACTIVIDAD DE LA DESHIDRATASA DE 6-FOSFOGLUCONATO O LA ACTIVIDAD DE LA ALDOLASA DE 2-CETO-3-DEOXI-6-FOSFOGLUCONATO O LAS ACTIVIDADES DE AMBAS SON AUMENTADAS Y EL L-AMINOACIDO ES SELECCIONADO DE LOS L-AMINOACIDOS PRODUCIDOS MEDIANTE UNA VIA BIOSINTETICA UTILIZANDO ACIDO PIRUVICO COMO INTERMEDIARIO
PE2003000298A 2002-03-27 2003-03-25 Metodo para producir l-aminoacido PE20031014A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002088668A JP3932945B2 (ja) 2002-03-27 2002-03-27 Ｌ−アミノ酸の製造法

Publications (1)

Publication Number Publication Date
PE20031014A1 true PE20031014A1 (es) 2004-02-05

Family

ID=28449463

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2003000298A PE20031014A1 (es) 2002-03-27 2003-03-25 Metodo para producir l-aminoacido

Country Status (16)

Country Link
US (2) US7037690B2 (es)
EP (1) EP1352966B1 (es)
JP (1) JP3932945B2 (es)
KR (1) KR100949048B1 (es)
CN (1) CN100529094C (es)
AT (1) ATE299945T1 (es)
AU (1) AU2003202509B2 (es)
BR (1) BR0300978B1 (es)
DE (1) DE60301031T2 (es)
DK (1) DK1352966T3 (es)
ES (1) ES2243826T3 (es)
MY (1) MY130526A (es)
PE (1) PE20031014A1 (es)
PL (1) PL359383A1 (es)
RU (1) RU2307165C2 (es)
TW (1) TWI308594B (es)

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AU756507B2 (en) * 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
JP4427878B2 (ja) 1999-08-20 2010-03-10 味の素株式会社 析出を伴う発酵法によるｌ−グルタミン酸の製造法
JP4599726B2 (ja) 2001-02-20 2010-12-15 味の素株式会社 Ｌ−グルタミン酸の製造法
JP3932945B2 (ja) * 2002-03-27 2007-06-20 味の素株式会社 Ｌ−アミノ酸の製造法
JP2004166595A (ja) 2002-11-20 2004-06-17 Ajinomoto Co Inc メチロトローフを用いたｌ−アミノ酸の製造法
RU2005138030A (ru) 2003-05-07 2006-04-20 Адзиномото Ко., Инк. (Jp) Способ получения l-глутаминовой кислоты
AU2004248005A1 (en) 2003-06-10 2004-12-23 Ajinomoto Co., Inc. Process for producing L-glutamic acid
DE102004003410A1 (de) * 2004-01-23 2005-08-25 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
DE102004014280A1 (de) * 2004-03-22 2005-10-27 Degussa Ag Verfahren zur Herstellung von optisch aktiven Aminosäuren mittels eines Ganzzellkatalysators
US7300776B2 (en) * 2004-04-26 2007-11-27 Ajinomoto Co., Inc. L-amino acid-producing bacterium and a method for producing L-amino acid
JP4984423B2 (ja) * 2004-04-26 2012-07-25 味の素株式会社 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
RU2004124226A (ru) * 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
US7501282B2 (en) 2005-02-25 2009-03-10 Ajinomoto Co., Inc. Plasmid autonomously replicable in Enterobacteriaceae family
JP2009118740A (ja) * 2006-03-03 2009-06-04 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
KR100885616B1 (ko) * 2006-06-26 2009-02-24 씨제이제일제당 (주) 글리세롤을 이용한 아미노산의 생산 방법
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
WO2008090770A1 (ja) 2007-01-22 2008-07-31 Ajinomoto Co., Inc. Ｌ－アミノ酸を生産する微生物及びｌ－アミノ酸の製造法
JP2010088301A (ja) 2007-02-01 2010-04-22 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
WO2008133161A1 (ja) 2007-04-17 2008-11-06 Ajinomoto Co., Inc. カルボキシル基を有する酸性物質の製造法
RU2395579C2 (ru) 2007-12-21 2010-07-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia
WO2010027022A1 (ja) 2008-09-05 2010-03-11 味の素株式会社 Ｌ－アミノ酸生産菌及びｌ－アミノ酸の製造法
ES2624913T3 (es) 2008-09-08 2017-07-18 Ajinomoto Co., Inc. Microorganismo que produce un L-aminoácido y procedimiento para producir un L-aminoácido
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
US20100120105A1 (en) * 2008-10-27 2010-05-13 Butamax (Tm) Advanced Biofuels Llc Carbon pathway optimized production hosts for the production of isobutanol
CA2767259A1 (en) * 2009-07-09 2011-01-13 Verdezyne, Inc. Engineered microorganisms with enhanced fermentation activity
WO2013069634A1 (ja) 2011-11-11 2013-05-16 味の素株式会社 発酵法による目的物質の製造法
WO2013071226A1 (en) * 2011-11-11 2013-05-16 Genomatica, Inc. Eukaryotic organisms and methods for increasing the availability of cytosolic acetyl-coa, and for producing 1,3-butanediol
PL2811028T3 (pl) * 2013-06-03 2017-07-31 Evonik Degussa Gmbh Sposób wytwarzania L-waliny z zastosowaniem zrekombinowanych bakterii maczugowatych zawierających operon ilvBN indukowany propionianem
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのｌ−アミノ酸の製造方法
CN104736707B (zh) 2013-10-21 2017-08-25 味之素株式会社 生产l‑氨基酸的方法
KR101835173B1 (ko) * 2014-06-23 2018-03-07 씨제이제일제당 (주) L-트립토판 생산능을 갖는 에스케리키아속 미생물 및 이를 이용한 l-트립토판의 제조 방법
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 Ｌ－アミノ酸の製造法
EP3789480A4 (en) * 2018-05-01 2022-03-23 Research Institute Of Innovative Technology For The Earth TRANSFORMER AND METHOD FOR PRODUCTION OF ORGANIC COMPOUND USING THE SAME
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
BR112021014194A2 (pt) 2019-02-22 2021-12-28 Ajinomoto Kk Método para a produção de um l-aminoácido
BR112021017870A2 (pt) 2019-04-05 2021-12-07 Ajinomoto Kk Método para produzir um l-aminoácido
JP2022550084A (ja) 2019-09-25 2022-11-30 味の素株式会社 細菌の発酵によるｌ－アミノ酸の製造方法
CN113278568B (zh) * 2020-05-27 2022-10-21 安徽华恒生物科技股份有限公司 生产l-缬氨酸的重组大肠杆菌及其应用

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JPH07155184A (ja) * 1993-12-08 1995-06-20 Ajinomoto Co Inc 発酵法によるｌ−リジンの製造法
GB9405629D0 (en) * 1994-03-22 1994-05-11 Whitbread & Co Ltd Recombinant DNA for use in yeast
AU756507B2 (en) 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
AU761990B2 (en) * 1998-10-19 2003-06-12 Ajinomoto Co., Inc. L-glutamic acid producing bacterium and process for producing L-glutamic acid
JP2003159092A (ja) 1999-07-02 2003-06-03 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2003180355A (ja) 1999-07-02 2003-07-02 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP4427878B2 (ja) 1999-08-20 2010-03-10 味の素株式会社 析出を伴う発酵法によるｌ−グルタミン酸の製造法
WO2001048146A1 (fr) 1999-12-24 2001-07-05 Ajinomoto Co., Inc. Procede de production d'acide l-amine et nouveau gene
JP2002238592A (ja) 2001-02-20 2002-08-27 Ajinomoto Co Inc Ｌ−グルタミン酸の製造法
DE10135051A1 (de) * 2001-07-18 2003-02-06 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
JP3932945B2 (ja) * 2002-03-27 2007-06-20 味の素株式会社 Ｌ−アミノ酸の製造法
JP2004166595A (ja) * 2002-11-20 2004-06-17 Ajinomoto Co Inc メチロトローフを用いたｌ−アミノ酸の製造法

Also Published As

Publication number Publication date
KR100949048B1 (ko) 2010-03-25
EP1352966A2 (en) 2003-10-15
MY130526A (en) 2007-06-29
EP1352966B1 (en) 2005-07-20
CN1446920A (zh) 2003-10-08
TW200306352A (en) 2003-11-16
AU2003202509B2 (en) 2007-12-13
JP2003274988A (ja) 2003-09-30
CN100529094C (zh) 2009-08-19
DK1352966T3 (da) 2005-08-08
JP3932945B2 (ja) 2007-06-20
BR0300978B1 (pt) 2014-02-25
EP1352966A3 (en) 2004-01-21
BR0300978A (pt) 2004-09-08
DE60301031T2 (de) 2006-06-01
ES2243826T3 (es) 2005-12-01
AU2003202509A1 (en) 2003-10-16
US20030219882A1 (en) 2003-11-27
RU2307165C2 (ru) 2007-09-27
US7432085B2 (en) 2008-10-07
PL359383A1 (en) 2003-10-06
TWI308594B (en) 2009-04-11
US20060115878A1 (en) 2006-06-01
KR20030078036A (ko) 2003-10-04
US7037690B2 (en) 2006-05-02
DE60301031D1 (de) 2005-08-25
ATE299945T1 (de) 2005-08-15

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