ATE299945T1 - Verfahren zur herstellung von l-aminosäuren - Google Patents
Verfahren zur herstellung von l-aminosäurenInfo
- Publication number
- ATE299945T1 ATE299945T1 AT03006936T AT03006936T ATE299945T1 AT E299945 T1 ATE299945 T1 AT E299945T1 AT 03006936 T AT03006936 T AT 03006936T AT 03006936 T AT03006936 T AT 03006936T AT E299945 T1 ATE299945 T1 AT E299945T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- producing
- medium
- amino acids
- microorganism
- Prior art date
Links
- 150000008575 L-amino acids Chemical class 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 230000004619 Entner-Doudoroff pathway Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 108010038136 phospho-2-keto-3-deoxy-gluconate aldolase Proteins 0.000 abstract 1
- 108010022393 phosphogluconate dehydratase Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002088668A JP3932945B2 (ja) | 2002-03-27 | 2002-03-27 | Ｌ−アミノ酸の製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE299945T1 true ATE299945T1 (de) | 2005-08-15 |
Family
ID=28449463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03006936T ATE299945T1 (de) | 2002-03-27 | 2003-03-26 | Verfahren zur herstellung von l-aminosäuren |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7037690B2 (de) |
| EP (1) | EP1352966B1 (de) |
| JP (1) | JP3932945B2 (de) |
| KR (1) | KR100949048B1 (de) |
| CN (1) | CN100529094C (de) |
| AT (1) | ATE299945T1 (de) |
| AU (1) | AU2003202509B2 (de) |
| BR (1) | BR0300978B1 (de) |
| DE (1) | DE60301031T2 (de) |
| DK (1) | DK1352966T3 (de) |
| ES (1) | ES2243826T3 (de) |
| MY (1) | MY130526A (de) |
| PE (1) | PE20031014A1 (de) |
| PL (1) | PL359383A1 (de) |
| RU (1) | RU2307165C2 (de) |
| TW (1) | TWI308594B (de) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU756507B2 (en) * | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
| JP4427878B2 (ja) | 1999-08-20 | 2010-03-10 | 味の素株式会社 | 析出を伴う発酵法によるｌ−グルタミン酸の製造法 |
| JP4599726B2 (ja) | 2001-02-20 | 2010-12-15 | 味の素株式会社 | Ｌ−グルタミン酸の製造法 |
| JP3932945B2 (ja) * | 2002-03-27 | 2007-06-20 | 味の素株式会社 | Ｌ−アミノ酸の製造法 |
| JP2004166595A (ja) | 2002-11-20 | 2004-06-17 | Ajinomoto Co Inc | メチロトローフを用いたｌ−アミノ酸の製造法 |
| EP1624069A4 (de) | 2003-05-07 | 2011-06-29 | Ajinomoto Kk | Verfahren zur herstellung von l-glutaminsäure |
| JPWO2004111258A1 (ja) | 2003-06-10 | 2006-07-27 | 味の素株式会社 | Ｌ−グルタミン酸の製造法 |
| DE102004003410A1 (de) * | 2004-01-23 | 2005-08-25 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| DE102004014280A1 (de) * | 2004-03-22 | 2005-10-27 | Degussa Ag | Verfahren zur Herstellung von optisch aktiven Aminosäuren mittels eines Ganzzellkatalysators |
| JP4984423B2 (ja) * | 2004-04-26 | 2012-07-25 | 味の素株式会社 | Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法 |
| US7300776B2 (en) * | 2004-04-26 | 2007-11-27 | Ajinomoto Co., Inc. | L-amino acid-producing bacterium and a method for producing L-amino acid |
| RU2004124226A (ru) | 2004-08-10 | 2006-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Использование фосфокетолазы для продукции полезных метаболитов |
| US7501282B2 (en) | 2005-02-25 | 2009-03-10 | Ajinomoto Co., Inc. | Plasmid autonomously replicable in Enterobacteriaceae family |
| JP2009118740A (ja) * | 2006-03-03 | 2009-06-04 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| KR100885616B1 (ko) * | 2006-06-26 | 2009-02-24 | 씨제이제일제당 (주) | 글리세롤을 이용한 아미노산의 생산 방법 |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| WO2008090770A1 (ja) | 2007-01-22 | 2008-07-31 | Ajinomoto Co., Inc. | Ｌ－アミノ酸を生産する微生物及びｌ－アミノ酸の製造法 |
| JP2010088301A (ja) | 2007-02-01 | 2010-04-22 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2010130899A (ja) | 2007-03-14 | 2010-06-17 | Ajinomoto Co Inc | Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法 |
| JP5218400B2 (ja) | 2007-04-17 | 2013-06-26 | 味の素株式会社 | カルボキシル基を有する酸性物質の製造法 |
| RU2395579C2 (ru) | 2007-12-21 | 2010-07-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia |
| JP5488467B2 (ja) | 2008-09-05 | 2014-05-14 | 味の素株式会社 | Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法 |
| CN102177246B (zh) | 2008-09-08 | 2015-02-11 | 味之素株式会社 | 生产l-氨基酸的微生物和l-氨基酸的生产方法 |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| BRPI0914521A2 (pt) * | 2008-10-27 | 2016-07-26 | Butamax Advanced Biofuels Llc | célula hospedeira microbiana recombinante, método de aumento da produção de isobutanol e método de produção de isobutanol |
| AP3766A (en) * | 2009-07-09 | 2016-07-31 | Du Pont | Engineered microorganisms with enhanced fermentation activity |
| BR112013016373B1 (pt) | 2011-11-11 | 2021-05-18 | Ajinomoto Co., Inc | método para produzir uma substância alvo |
| US20140322779A1 (en) * | 2011-11-11 | 2014-10-30 | Genomatica, Inc. | Eukaryotic organisms and methods for increasing the availability of cytosolic acetyl-coa, and for the producing 1,3-butanediol |
| DK2811028T3 (en) | 2013-06-03 | 2017-05-01 | Evonik Degussa Gmbh | Process for Preparation of L-Valine Using Recombinant Coryn Bacteria Containing the Propionate Inducible IlvBN Operon |
| JP2016165225A (ja) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | 有用物質の製造方法 |
| JP2016192903A (ja) * | 2013-09-17 | 2016-11-17 | 味の素株式会社 | 海藻由来バイオマスからのｌ−アミノ酸の製造方法 |
| EP2886651B1 (de) | 2013-10-21 | 2018-08-22 | Ajinomoto Co., Inc. | Verfahren zur herstellung von l-aminosäure |
| KR101835173B1 (ko) * | 2014-06-23 | 2018-03-07 | 씨제이제일제당 (주) | L-트립토판 생산능을 갖는 에스케리키아속 미생물 및 이를 이용한 l-트립토판의 제조 방법 |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| JP7066977B2 (ja) | 2017-04-03 | 2022-05-16 | 味の素株式会社 | Ｌ－アミノ酸の製造法 |
| US11459574B2 (en) | 2018-05-01 | 2022-10-04 | Research Institute Of Innovative Technology For The Earth | Transformant having Entner-Doudoroff pathway and production method for organic compound using same |
| WO2020071538A1 (en) | 2018-10-05 | 2020-04-09 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
| WO2020171227A1 (en) | 2019-02-22 | 2020-08-27 | Ajinomoto Co., Inc. | METHOD FOR PRODUCING L-AMINO ACIDS USING A BACTERIUM BELONGING TO THE FAMILY Enterobacteriaceae HAVING OVEREXPRESSED ydiJ GENE |
| JP7524909B2 (ja) | 2019-04-05 | 2024-07-30 | 味の素株式会社 | Ｌ－アミノ酸の製造方法 |
| JP7655312B2 (ja) | 2019-09-25 | 2025-04-02 | 味の素株式会社 | 細菌の発酵によるｌ－アミノ酸の製造方法 |
| CN113278568B (zh) * | 2020-05-27 | 2022-10-21 | 安徽华恒生物科技股份有限公司 | 生产l-缬氨酸的重组大肠杆菌及其应用 |
| US20240117393A1 (en) | 2022-09-30 | 2024-04-11 | Ajinomoto Co., Inc. | Method for producing l-amino acid |
| CN116536292A (zh) * | 2022-11-04 | 2023-08-04 | 吉林梅花氨基酸有限责任公司 | 磷酸葡萄糖酸脱水酶突变体及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1694643A1 (ru) * | 1987-11-26 | 1991-11-30 | Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Штамм бактерий ЕSснеRIснIа coLI - продуцент L-треонина |
| JPH07155184A (ja) * | 1993-12-08 | 1995-06-20 | Ajinomoto Co Inc | 発酵法によるｌ−リジンの製造法 |
| GB9405629D0 (en) * | 1994-03-22 | 1994-05-11 | Whitbread & Co Ltd | Recombinant DNA for use in yeast |
| AU756507B2 (en) * | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
| AU761990B2 (en) | 1998-10-19 | 2003-06-12 | Ajinomoto Co., Inc. | L-glutamic acid producing bacterium and process for producing L-glutamic acid |
| JP2003180355A (ja) | 1999-07-02 | 2003-07-02 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2003159092A (ja) | 1999-07-02 | 2003-06-03 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP4427878B2 (ja) | 1999-08-20 | 2010-03-10 | 味の素株式会社 | 析出を伴う発酵法によるｌ−グルタミン酸の製造法 |
| KR20020073153A (ko) | 1999-12-24 | 2002-09-19 | 아지노모토 가부시키가이샤 | Ｌ-아미노산의 제조법 및 신규 유전자 |
| JP2002238592A (ja) * | 2001-02-20 | 2002-08-27 | Ajinomoto Co Inc | Ｌ−グルタミン酸の製造法 |
| DE10135051A1 (de) * | 2001-07-18 | 2003-02-06 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| JP3932945B2 (ja) * | 2002-03-27 | 2007-06-20 | 味の素株式会社 | Ｌ−アミノ酸の製造法 |
| JP2004166595A (ja) * | 2002-11-20 | 2004-06-17 | Ajinomoto Co Inc | メチロトローフを用いたｌ−アミノ酸の製造法 |
-
2002
- 2002-03-27 JP JP2002088668A patent/JP3932945B2/ja not_active Expired - Lifetime
-
2003
- 2003-03-25 PE PE2003000298A patent/PE20031014A1/es active IP Right Grant
- 2003-03-25 AU AU2003202509A patent/AU2003202509B2/en not_active Expired - Fee Related
- 2003-03-26 AT AT03006936T patent/ATE299945T1/de not_active IP Right Cessation
- 2003-03-26 DK DK03006936T patent/DK1352966T3/da active
- 2003-03-26 MY MYPI20031113A patent/MY130526A/en unknown
- 2003-03-26 EP EP03006936A patent/EP1352966B1/de not_active Expired - Lifetime
- 2003-03-26 ES ES03006936T patent/ES2243826T3/es not_active Expired - Lifetime
- 2003-03-26 US US10/396,488 patent/US7037690B2/en not_active Expired - Lifetime
- 2003-03-26 RU RU2003108441/13A patent/RU2307165C2/ru not_active IP Right Cessation
- 2003-03-26 DE DE60301031T patent/DE60301031T2/de not_active Expired - Lifetime
- 2003-03-27 TW TW092107210A patent/TWI308594B/zh not_active IP Right Cessation
- 2003-03-27 CN CNB031226884A patent/CN100529094C/zh not_active Expired - Lifetime
- 2003-03-27 PL PL03359383A patent/PL359383A1/xx not_active Application Discontinuation
- 2003-03-27 BR BRPI0300978-5B1A patent/BR0300978B1/pt active IP Right Grant
- 2003-03-27 KR KR1020030019209A patent/KR100949048B1/ko not_active Expired - Lifetime
-
2005
- 2005-11-18 US US11/281,495 patent/US7432085B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60301031T2 (de) | 2006-06-01 |
| PE20031014A1 (es) | 2004-02-05 |
| KR100949048B1 (ko) | 2010-03-25 |
| DE60301031D1 (de) | 2005-08-25 |
| EP1352966B1 (de) | 2005-07-20 |
| TW200306352A (en) | 2003-11-16 |
| EP1352966A2 (de) | 2003-10-15 |
| BR0300978A (pt) | 2004-09-08 |
| US20030219882A1 (en) | 2003-11-27 |
| CN1446920A (zh) | 2003-10-08 |
| JP3932945B2 (ja) | 2007-06-20 |
| CN100529094C (zh) | 2009-08-19 |
| US7037690B2 (en) | 2006-05-02 |
| BR0300978B1 (pt) | 2014-02-25 |
| KR20030078036A (ko) | 2003-10-04 |
| JP2003274988A (ja) | 2003-09-30 |
| MY130526A (en) | 2007-06-29 |
| ES2243826T3 (es) | 2005-12-01 |
| RU2307165C2 (ru) | 2007-09-27 |
| DK1352966T3 (da) | 2005-08-08 |
| EP1352966A3 (de) | 2004-01-21 |
| US7432085B2 (en) | 2008-10-07 |
| AU2003202509A1 (en) | 2003-10-16 |
| AU2003202509B2 (en) | 2007-12-13 |
| TWI308594B (en) | 2009-04-11 |
| US20060115878A1 (en) | 2006-06-01 |
| PL359383A1 (en) | 2003-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |