ATE201443T1 - Verfahren zur herstellung von aspartase und l- asparginsäure - Google Patents
Verfahren zur herstellung von aspartase und l- asparginsäureInfo
- Publication number
- ATE201443T1 ATE201443T1 AT97104568T AT97104568T ATE201443T1 AT E201443 T1 ATE201443 T1 AT E201443T1 AT 97104568 T AT97104568 T AT 97104568T AT 97104568 T AT97104568 T AT 97104568T AT E201443 T1 ATE201443 T1 AT E201443T1
- Authority
- AT
- Austria
- Prior art keywords
- aspartase
- producing
- aspartic acid
- culture
- medium
- Prior art date
Links
- 108700016171 Aspartate ammonia-lyases Proteins 0.000 title abstract 6
- CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Natural products OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 title abstract 3
- CKLJMWTZIZZHCS-UWTATZPHSA-N L-Aspartic acid Natural products OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 title abstract 3
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 title abstract 3
- 229960005261 aspartic acid Drugs 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 2
- 239000002609 medium Substances 0.000 abstract 2
- 241000588722 Escherichia Species 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 230000003698 anagen phase Effects 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000001530 fumaric acid Substances 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/20—Aspartic acid; Asparagine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7598996 | 1996-03-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE201443T1 true ATE201443T1 (de) | 2001-06-15 |
Family
ID=13592199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97104568T ATE201443T1 (de) | 1996-03-29 | 1997-03-18 | Verfahren zur herstellung von aspartase und l- asparginsäure |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5916782A (de) |
| EP (1) | EP0798377B1 (de) |
| KR (1) | KR970065723A (de) |
| CN (1) | CN1165860A (de) |
| AT (1) | ATE201443T1 (de) |
| AU (1) | AU708588B2 (de) |
| CA (1) | CA2200420A1 (de) |
| DE (1) | DE69704900T2 (de) |
| DK (1) | DK0798377T3 (de) |
| ES (1) | ES2159372T3 (de) |
| PT (1) | PT798377E (de) |
| TW (1) | TW487733B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0823482A3 (de) * | 1996-08-09 | 1998-09-09 | Nippon Shokubai Co., Ltd. | Verfahren zur Herstellung von L-Asparaginsäure und zur Umwandlung von Maleinsäure in Fumarsäure |
| EP0945513B1 (de) * | 1998-02-13 | 2005-09-21 | Nippon Shokubai Co., Ltd. | Verfahren zur Herstellung von L-Asparaginsäure |
| AT408755B (de) * | 1998-05-22 | 2002-03-25 | Dsm Fine Chem Austria Gmbh | Verfahren zur herstellung von l-asparaginsäure |
| WO2006069610A2 (en) | 2004-07-02 | 2006-07-06 | Metanomics Gmbh | Process for the production of fine chemicals |
| WO2007087815A2 (en) * | 2004-12-17 | 2007-08-09 | Metanomics Gmbh | Process for the control of production of fine chemicals |
| CN102559538B (zh) * | 2011-11-25 | 2014-04-09 | 烟台恒源生物股份有限公司 | 高产l-天冬氨酸酶的大肠埃希氏菌及其应用 |
| CN102660527B (zh) * | 2012-05-30 | 2013-07-03 | 山东大学 | 利用原料预处理和补料发酵生产高酶活碱性果胶酶的方法 |
| CN104593306B (zh) * | 2015-02-04 | 2017-06-23 | 烟台恒源生物股份有限公司 | 一种大肠埃希氏菌株hy‑05c高密度培养方法 |
| CN104845921B (zh) * | 2015-06-15 | 2018-02-27 | 中国食品发酵工业研究院 | 一株噬菌体抗性l‑天冬氨酸转化菌及其应用 |
| CN105316273B (zh) * | 2015-11-24 | 2019-08-30 | 南京工业大学 | 一株无苹果酸副产的l-天冬氨酸酶重组大肠杆菌及其构建方法与应用 |
| CN108531525A (zh) * | 2018-05-09 | 2018-09-14 | 宿州学院 | 一种l-天冬氨酸的酶法转化制备方法 |
| CN109337941A (zh) * | 2018-09-29 | 2019-02-15 | 宿州学院 | 一种l-天冬氨酸的质控生产方法及其应用 |
| CN109970587B (zh) * | 2019-05-06 | 2024-04-30 | 宿州学院 | 一种l-天冬氨酸分离提纯装置及其分离提纯l-天冬氨酸的方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5412553A (en) * | 1977-06-29 | 1979-01-30 | Toshiba Corp | Microwave oscillation circuit |
| JPS5718867A (en) * | 1980-07-08 | 1982-01-30 | Nissan Motor Co Ltd | Pressure control valve |
| ZA824805B (en) * | 1981-10-15 | 1983-04-27 | Genex Corp | Production of aspartase |
| US4436813A (en) * | 1982-03-16 | 1984-03-13 | Purification Engineering, Inc. | Immobilized microbial cell composition for making L-aspartic acid |
| AU1763083A (en) * | 1982-08-13 | 1984-02-16 | Board Of Trustees Of The Leland Stanford Junior University | Method of immobilizing enzymes |
| JPS59113895A (ja) * | 1982-12-03 | 1984-06-30 | Tanabe Seiyaku Co Ltd | Ｌ−アスパラギン酸の製法 |
| US4560653A (en) * | 1983-06-06 | 1985-12-24 | W. R. Grace & Co. | Process for preparing L-aspartic acid |
| JPS59232088A (ja) * | 1983-06-15 | 1984-12-26 | Tanabe Seiyaku Co Ltd | Ｌ−アスパラギン酸の製法 |
| JPS60133883A (ja) * | 1983-12-20 | 1985-07-17 | Tanabe Seiyaku Co Ltd | 新規微生物及びそれを用いるｌ−アスパラギン酸の製法 |
| US4698224A (en) * | 1984-04-10 | 1987-10-06 | Kirin Beer Kabushiki Kaisha | Production of alcoholic beverages |
| JP2501124B2 (ja) * | 1989-07-25 | 1996-05-29 | 松下電工株式会社 | プリント基板の小径穴あけ方法 |
| JP3009257B2 (ja) * | 1991-07-25 | 2000-02-14 | 三菱化学株式会社 | アスパルターゼをコードする遺伝子ｄｎａ及びその利用 |
| US5441634A (en) * | 1993-07-06 | 1995-08-15 | Edwards Laboratories, Inc. | Apparatus and method of circulating a body of fluid containing a mixture of solid waste and water and separating them |
| JP2664648B2 (ja) * | 1994-05-20 | 1997-10-15 | 株式会社日本触媒 | Ｌ−アスパラギン酸の製造方法 |
| US5677156A (en) * | 1995-04-04 | 1997-10-14 | Mitsubishi Chemical Corporation | Method for producing fumaric acid |
| EP0823482A3 (de) * | 1996-08-09 | 1998-09-09 | Nippon Shokubai Co., Ltd. | Verfahren zur Herstellung von L-Asparaginsäure und zur Umwandlung von Maleinsäure in Fumarsäure |
-
1997
- 1997-03-18 AT AT97104568T patent/ATE201443T1/de not_active IP Right Cessation
- 1997-03-18 DK DK97104568T patent/DK0798377T3/da active
- 1997-03-18 EP EP97104568A patent/EP0798377B1/de not_active Expired - Lifetime
- 1997-03-18 ES ES97104568T patent/ES2159372T3/es not_active Expired - Lifetime
- 1997-03-18 DE DE69704900T patent/DE69704900T2/de not_active Expired - Fee Related
- 1997-03-18 PT PT97104568T patent/PT798377E/pt unknown
- 1997-03-19 CA CA002200420A patent/CA2200420A1/en not_active Abandoned
- 1997-03-24 TW TW086103694A patent/TW487733B/zh not_active IP Right Cessation
- 1997-03-24 US US08/822,002 patent/US5916782A/en not_active Expired - Fee Related
- 1997-03-25 AU AU16506/97A patent/AU708588B2/en not_active Ceased
- 1997-03-28 CN CN97109695A patent/CN1165860A/zh active Pending
- 1997-03-29 KR KR1019970011391A patent/KR970065723A/ko not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0798377A2 (de) | 1997-10-01 |
| AU708588B2 (en) | 1999-08-05 |
| EP0798377A3 (de) | 1998-09-09 |
| EP0798377B1 (de) | 2001-05-23 |
| US5916782A (en) | 1999-06-29 |
| PT798377E (pt) | 2001-08-30 |
| AU1650697A (en) | 1997-10-02 |
| CA2200420A1 (en) | 1997-09-29 |
| DE69704900D1 (de) | 2001-06-28 |
| CN1165860A (zh) | 1997-11-26 |
| ES2159372T3 (es) | 2001-10-01 |
| TW487733B (en) | 2002-05-21 |
| DE69704900T2 (de) | 2001-10-25 |
| KR970065723A (ko) | 1997-10-13 |
| DK0798377T3 (da) | 2001-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |