BRPI0418720A - método para cultivar a cepa de rhodococcus rhodochrous m33 produtora de nitrila hidratase, e, meio de cultura - Google Patents

método para cultivar a cepa de rhodococcus rhodochrous m33 produtora de nitrila hidratase, e, meio de cultura

Info

Publication number
BRPI0418720A
BRPI0418720A BRPI0418720-2A BRPI0418720A BRPI0418720A BR PI0418720 A BRPI0418720 A BR PI0418720A BR PI0418720 A BRPI0418720 A BR PI0418720A BR PI0418720 A BRPI0418720 A BR PI0418720A
Authority
BR
Brazil
Prior art keywords
nitrile hydratase
cultivating
culture medium
strain producing
rhodococcus rhodochrous
Prior art date
Application number
BRPI0418720-2A
Other languages
English (en)
Inventor
Josef Lorenz
S P Woronin
I N Singirzev
V G Debabov
A S Yanenko
S W Kosolin
Original Assignee
Ashland Licensing & Intellectu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ashland Licensing & Intellectu filed Critical Ashland Licensing & Intellectu
Publication of BRPI0418720A publication Critical patent/BRPI0418720A/pt
Publication of BRPI0418720B1 publication Critical patent/BRPI0418720B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01084—Nitrile hydratase (4.2.1.84)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

"MéTODO PARA CULTIVAR A CEPA DE RHODOCOCCUS RHODOCHROUS M33 PRODUTORA DE NITRILA HIDRATASE, E, MEIO DE CULTURA" A invenção refere-se a um método para cultivar a cepa de Rhodococcus rhodochrous M33 produtora de nitrila hidratase, empregando-se um meio de cultura que se baseia em um tampão de fosfato com de 12 a 60 mM e que atende a necessidade de fósforo das células, mantendo-se o valor do pH durante a cultura na faixa de 5,5 a 9,0, e, após o consumo da quantidade inicialmente carregada de glucose, adiciona-se ácido acético como nova fonte de carbono. A invenção refere-se também ao meio de cultura empregado no processo.
BRPI0418720A 2003-04-03 2004-04-06 método para cultivar a cepa de rhodococcus rhodochrous m33 produtora de nitrila hidratase, e, uso de meio de cultura BRPI0418720B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10315376A DE10315376B4 (de) 2003-04-03 2003-04-03 Verfahren zur Kultivierung des Nitrilhydratase-produzierenden Stammes RHODOCOCCUS RHODOCHROUS M33
PCT/EP2004/003611 WO2005108553A1 (de) 2003-04-03 2004-04-06 Verfahren zur kultivierung des nitrilhydratase-produzierenden stammes rodococcus rhodochrous m33

Publications (2)

Publication Number Publication Date
BRPI0418720A true BRPI0418720A (pt) 2007-09-11
BRPI0418720B1 BRPI0418720B1 (pt) 2016-04-12

Family

ID=33103196

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0418720A BRPI0418720B1 (pt) 2003-04-03 2004-04-06 método para cultivar a cepa de rhodococcus rhodochrous m33 produtora de nitrila hidratase, e, uso de meio de cultura

Country Status (10)

Country Link
US (1) US20050239165A1 (pt)
EP (1) EP1737946B1 (pt)
JP (1) JP4584982B2 (pt)
KR (1) KR101116451B1 (pt)
CN (1) CN1961067B (pt)
AT (1) ATE485365T1 (pt)
BR (1) BRPI0418720B1 (pt)
DE (2) DE10315376B4 (pt)
RU (1) RU2340667C2 (pt)
WO (1) WO2005108553A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10315376B4 (de) * 2003-04-03 2005-07-14 Stockhausen Gmbh Verfahren zur Kultivierung des Nitrilhydratase-produzierenden Stammes RHODOCOCCUS RHODOCHROUS M33
US8679782B2 (en) 2009-06-15 2014-03-25 Massachusetts Institute Of Technology Production of triacylglycerides, fatty acids, and their derivatives
CN102286409B (zh) * 2009-07-16 2013-04-24 浙江工业大学 紫红红球菌及其催化亚氨基二乙腈制备亚氨基二乙酸
CN102776168A (zh) * 2012-07-20 2012-11-14 江苏南天农科化工有限公司 一种通过发酵补料培养分批培养提高酶活力的方法
RU2520870C1 (ru) 2012-12-27 2014-06-27 Кемира Оюй Штамм бактерий rhodococcus aetherivorans bkm ac-2610d - продуцент нитрилгидратазы, способ его культивирования и способ получения акриламида
EA032896B1 (ru) * 2017-06-15 2019-07-31 Акционерное Общество "Биоамид" Способ культивирования штамма rhodococcus rhodochrous m33

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6083581A (ja) * 1983-10-13 1985-05-11 Hideaki Yamada シユ−ドモナス属細菌の培養法
US5179014A (en) * 1985-01-08 1993-01-12 Nitto Chemical Industry Co., Ltd. Process for the preparation of amides using microorganisms
EP0319123B1 (en) * 1987-11-30 1995-05-17 The Agency of Industrial Science and Technology Process for producing unsaturated fatty acid or unsaturated hydrocarbon
CZ280901B6 (cs) * 1988-10-06 1996-05-15 Hideaki Yamada Způsob kultivace bakterií
RU2053300C1 (ru) * 1993-12-17 1996-01-27 Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Штамм бактерий rhodococcus rhodochrous - продуцент нитрилгидратазы
DE60043424D1 (de) * 1999-10-26 2010-01-14 Showa Denko Kk Rhodococcus-stamm, nitrilase-gen aus rhodococcus, nitrilhydratas-gen und amidase-gen und verfahren zur herstellung carboxylsäuren unter deren verwendung
RU2177034C1 (ru) * 2001-04-03 2001-12-20 Закрытое акционерное общество "Биоамид" Штамм бактерий alcaligenes denitrificans-продуцент нитрилазы
DE10315376B4 (de) * 2003-04-03 2005-07-14 Stockhausen Gmbh Verfahren zur Kultivierung des Nitrilhydratase-produzierenden Stammes RHODOCOCCUS RHODOCHROUS M33

Also Published As

Publication number Publication date
JP4584982B2 (ja) 2010-11-24
WO2005108553A1 (de) 2005-11-17
CN1961067A (zh) 2007-05-09
EP1737946B1 (de) 2010-10-20
CN1961067B (zh) 2011-05-18
KR20070026439A (ko) 2007-03-08
EP1737946A1 (de) 2007-01-03
ATE485365T1 (de) 2010-11-15
RU2006139069A (ru) 2008-05-27
DE502004011806D1 (de) 2010-12-02
DE10315376B4 (de) 2005-07-14
JP2007531535A (ja) 2007-11-08
US20050239165A1 (en) 2005-10-27
BRPI0418720B1 (pt) 2016-04-12
RU2340667C2 (ru) 2008-12-10
KR101116451B1 (ko) 2012-03-07
DE10315376A1 (de) 2004-11-04

Similar Documents

Publication Publication Date Title
PE20031014A1 (es) Metodo para producir l-aminoacido
BR0200452A (pt) Método para produzir ácido l-glut mico pela fermentação
DK1651758T3 (da) Fremgangsmåde tl fremstilling af L-lysin eller L-threonin ved anvendelse af Escherichia bakterier med svækket æblesyreenzymaktivitet
PL1664318T3 (pl) Mikroorganizm wytwarzający L-aminokwas i sposób wytwarzania L-aminokwasu
EP1571223A3 (en) L-cysteine-producing microorganism and a method for producing L-cysteine
BRPI0507717A (pt) microoganismo apresentado uma capacidade de produzir ácido l-glutámico, método para produzir ácido l-glutámico, e, gene
BR9901174A (pt) Microorganismo pertencente ao gênero klebsiella, ao gênero erwinia ou ao gênero pantoea e processo para produzir ácido l-glutâmico
ID24398A (id) Metode untuk menghasilkan asam l-amino
BR0200285A (pt) Bactéria corineforme, e método para a produção de l-cisteìna
EP0913466A3 (en) Method for producing L-leucine
MY127434A (en) Method for producing substance utilizing microorganism
BR9904747A (pt) Microorganismo, e, processo para prodizir ácido l-glutâmico
BR0106255A (pt) Método papa produzir uma substância alvo pela utilização de um microorganismo
PT870016E (pt) Enzimas sua preparacao e utilizacao na producao de acrilato de amonio
BRPI0418720A (pt) método para cultivar a cepa de rhodococcus rhodochrous m33 produtora de nitrila hidratase, e, meio de cultura
BR0304860A (pt) Método para produzir uma substância alvo pela utilização de uma-bactéria pertencente ao gênero escherichia
BR0102669A (pt) Bactéria corineforme, método para produzir ácido l-glutâmico, e, dna
ATE307194T1 (de) Definiertes kulturmedium
DE60317165D1 (de) Bakterielle autolysate
BRPI0401947A (pt) Método para produzir um l-aminoácido, e, bactéria
JPS594987B2 (ja) ニトリラ−ゼ活性の高い細菌菌体の製造法
ES2160829T3 (es) Procedimiento para la obtencion de riboflavina por medio de microorganismos con actividad de isocitratoliasa modificada.
BR9903603A (pt) Processo para produzir um produto fermentativo utilizando um microorganismo, e, microorganismo
WO2005046581A3 (en) P18 in stem cell manipulations
BR0317507A (pt) Método para a produção de um aminoácido

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 3A ANUIDADE.

B08G Application fees: restoration [chapter 8.7 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B25A Requested transfer of rights approved

Owner name: SOLENIS TECHNOLOGIES CAYMAN, L.P. (CH)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 12/04/2016, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 19A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2717 DE 31-01-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.