PE20020471A1 - Nuevos polisacaridos de actividad antitrombotica que presentan por lo menos un enlace covalente con la biotina o un derivado de la biotina - Google Patents
Nuevos polisacaridos de actividad antitrombotica que presentan por lo menos un enlace covalente con la biotina o un derivado de la biotinaInfo
- Publication number
- PE20020471A1 PE20020471A1 PE2001000952A PE2001000952A PE20020471A1 PE 20020471 A1 PE20020471 A1 PE 20020471A1 PE 2001000952 A PE2001000952 A PE 2001000952A PE 2001000952 A PE2001000952 A PE 2001000952A PE 20020471 A1 PE20020471 A1 PE 20020471A1
- Authority
- PE
- Peru
- Prior art keywords
- glucopyranosil
- methyl
- tri
- biotin
- alcoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
SE REFIERE A POLISACARIDOS SINTETICOS DE FORMULA I DONDE EL TRAZO ONDULADO DESIGNA UN ENLACE SITUADO POR DEBAJO O POR ENCIMA DEL PLANO DEL CICLO PIRANOSICOS DONDE PO DESIGNA UN POLISACARIDO QUE CONTIENEN n UNIDADES MONOSACARIDAS IDENTICAS O DIFERENTES ENLAZADO POR SU CARBNO ANOMERO A Pe ; R1 ES T-BIOT, ALCOXI C1-C6, -OSO3-; R2 ES T-BIOT, ALCOXI C1-C6, -OS03-; R3 ES T-BIOT, ALCOXI C1-C6; R4 ES T-BIOT, ALCOXI C1-C6, -OSO3-; h ES 1- 2; n ES 0-25. UN COMPUESTO PREFERIDO ES METIL(2,3,4,6-TETRA-O-SULFONATO-O-D-GLUCOPIRANOSIL)-(1-4)-(2,3,6-TRI-O-SULFONATO-O-D-GLUCOPIRANOSIL)-(1-4)-(2,3,6-TRI-O-SULFONATO-ß-D-GLUCOPIRANOSIL)-(1-4)-(6-BIOTIN-AMIDO-6-DESOXI-2,3-di-O-METIL-O-D-GLUCOPIRANOSIL)-(1-4)-(2,3,6-TRI-O-METIL-ß-D-GLUCOPIRANOSIL)-(1-4)-O-[(2,3,6-TRI-O-METIL-O-D-GLUCOPIRANOSIL)-(1-4)-O-2,3,6-TRI-O-METIL-ß-D-GLUCOPIRANOSIL)-(1-4)]3-(6-O-SULFONATO-2,3-di-O-METIL-O-D-GLUCOPIRANOSIL)-(1-4)-ACIDO 2,3-DI-O-METIL-ß-D-GLUCOPIRANOSILURONICO)-(1-4)-(2,3,6-TRI-O-SULFONATO-O-D-GLUCOPIRANOSIL)-(1-4)-(ACIDO-2,3-di-O-METIL-O-L-IDOPIRANOSIL-URONICO)-(1-4)-2,3,6-TRI-O-SULFONATO-O-D-GLUCOPIRANOSIDA, SAL DE SODIO, ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO QUE APLICA LA AVIDINA O ESTREPTAVIDINA QUE PERMITEN NEUTRALIZAR DICHOS POLISACARIDOS. LOS COMPUESTOS MENCIONADOS TIENEN ACTIVIDAD ANTITROMBOTICA QUE PRESENTAN POR LO MENOS UN ENLACE COVALENTE CON LA BIOTINA O UN DERIVADO DE LA MISMA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0012094A FR2814463B1 (fr) | 2000-09-22 | 2000-09-22 | Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20020471A1 true PE20020471A1 (es) | 2002-06-01 |
Family
ID=8854579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000952A PE20020471A1 (es) | 2000-09-22 | 2001-09-21 | Nuevos polisacaridos de actividad antitrombotica que presentan por lo menos un enlace covalente con la biotina o un derivado de la biotina |
Country Status (40)
| Country | Link |
|---|---|
| US (3) | US6844329B2 (es) |
| EP (1) | EP1322673B1 (es) |
| JP (2) | JP5016778B2 (es) |
| KR (2) | KR20080049139A (es) |
| CN (1) | CN1235914C (es) |
| AR (1) | AR030774A1 (es) |
| AT (1) | ATE374215T1 (es) |
| AU (2) | AU9196001A (es) |
| BG (1) | BG66191B1 (es) |
| BR (1) | BR0114007A (es) |
| CA (1) | CA2418815C (es) |
| CY (1) | CY1108076T1 (es) |
| CZ (1) | CZ300856B6 (es) |
| DE (1) | DE60130669T2 (es) |
| DK (1) | DK1322673T3 (es) |
| EA (1) | EA005133B1 (es) |
| EC (1) | ECSP034514A (es) |
| EE (1) | EE05202B1 (es) |
| ES (1) | ES2292625T3 (es) |
| FR (1) | FR2814463B1 (es) |
| GE (1) | GEP20053616B (es) |
| HK (1) | HK1053316A1 (es) |
| HR (1) | HRP20030219B1 (es) |
| HU (2) | HUP0303551A3 (es) |
| IL (2) | IL154848A0 (es) |
| IS (1) | IS2550B (es) |
| ME (2) | MEP23608A (es) |
| MX (1) | MXPA03002483A (es) |
| NO (2) | NO332905B1 (es) |
| NZ (1) | NZ524472A (es) |
| PE (1) | PE20020471A1 (es) |
| PL (1) | PL206727B1 (es) |
| PT (1) | PT1322673E (es) |
| RS (1) | RS50730B (es) |
| SI (1) | SI1322673T1 (es) |
| SK (2) | SK287218B6 (es) |
| TW (1) | TWI308153B (es) |
| UA (1) | UA79736C2 (es) |
| WO (1) | WO2002024754A1 (es) |
| ZA (1) | ZA200301692B (es) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2814463B1 (fr) * | 2000-09-22 | 2002-11-15 | Sanofi Synthelabo | Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine |
| FR2874924B1 (fr) | 2004-09-09 | 2006-12-01 | Sanofi Aventis Sa | Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique |
| TWI403334B (zh) * | 2004-12-23 | 2013-08-01 | Merck Sharp & Dohme | 包含生物素殘基之抗血栓雙重抑制劑 |
| TWI376234B (en) * | 2005-02-01 | 2012-11-11 | Msd Oss Bv | Conjugates of a polypeptide and an oligosaccharide |
| DE602006020634D1 (de) * | 2005-10-10 | 2011-04-21 | Organon Nv | Antikoagulans/antithrombose-dual-hemmer mit einem biotin-label |
| US8183228B2 (en) * | 2005-10-10 | 2012-05-22 | MSD OSS B.V. Netherlands | Anticoagulant antithrombotic dual inhibitors comprising a biotin label |
| CN1317035C (zh) * | 2005-10-24 | 2007-05-23 | 天津大学 | 基于酰肼基的微粒表面多重生物功能因子组装方法 |
| EP1886696A1 (en) * | 2006-08-03 | 2008-02-13 | Endotis Pharma | Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins |
| FR2912409B1 (fr) * | 2007-02-14 | 2012-08-24 | Sanofi Aventis | Heparines de bas poids moleculaire comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine leur procede de preparation,leur utilisation |
| EP2233143A1 (en) | 2009-03-24 | 2010-09-29 | Sanofi-Aventis | Use of idrabiotaparinux for decreasing the incidence of bleedings during an antithrombotic treatment |
| EP2145624A1 (en) | 2008-07-18 | 2010-01-20 | Sanofi-Aventis | Use of idrabiotaparinux for decreasing the incidence of bleedings during an antithrombotic treatment |
| TW201006479A (en) * | 2008-07-18 | 2010-02-16 | Sanofi Aventis | Use of idrabiotaparinux for decreasing the incidence of bleedings during an antithrombotic treatment |
| FR2935386B1 (fr) * | 2008-08-26 | 2010-09-10 | Sanofi Aventis | Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine |
| EP2323605A4 (en) * | 2008-09-10 | 2014-02-05 | Syneron Medical Ltd | TRANSDERMAL RELEASE OF OLIGOSACCHARIDES |
| MX2019001413A (es) | 2008-12-19 | 2019-08-12 | Supernus Pharmaceuticals Inc | Uso de molindona para el tratamiento de agresion. |
| FR2952935B1 (fr) | 2009-11-20 | 2011-12-02 | Sanofi Aventis | Procede de preparation du n-biotinyl-6-aminocaproate de n succinimidyle |
| JP6109574B2 (ja) | 2009-12-18 | 2017-04-05 | カタラン、フランス、バインハイム、ソシエテ、アノニムＣａｔａｌｅｎｔ Ｆｒａｎｃｅ Ｂｅｉｎｈｅｉｍ Ｓａ | 合成オリゴサッカリドを含有する医薬経口剤形 |
| CZ302510B6 (cs) * | 2010-03-29 | 2011-06-22 | Univerzita Palackého v Olomouci | Efektivní zpusob biotinylace sloucenin s karboxylovou skupinou pomocí syntézy na pevné fázi pro potreby afinitní chromatografie |
| CZ302669B6 (cs) * | 2010-03-29 | 2011-08-24 | Univerzita Palackého v Olomouci | Efektivní zpusob biotinylace aminosloucenin pomocí syntézy na pevné fázi pro potreby afinitní chromatografie |
| ES2756711T3 (es) | 2010-03-31 | 2020-04-27 | Supernus Pharmaceuticals Inc | Formulaciones estabilizadas de compuestos del SNC |
| JP2013537181A (ja) * | 2010-09-10 | 2013-09-30 | サノフイ | 抗血栓活性及び改善された代謝安定性を有するビオチン化多糖類 |
| FR2964660B1 (fr) * | 2010-09-10 | 2012-09-28 | Sanofi Aventis | Nouveaux polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree |
| EP2484366A1 (en) | 2011-02-07 | 2012-08-08 | Sanofi | Idrabiotaparinux for the treatment of pulmonary embolism and for the secondary prevention of venous thromboembolic events |
| ES2560467T3 (es) * | 2011-06-17 | 2016-02-19 | Carbomimetics | Pentasacáridos sintéticos que tienen vida media corta y alta actividad |
| JP2015536999A (ja) * | 2012-11-13 | 2015-12-24 | スパーナス ファーマシューティカルズ インコーポレイテッド | 攻撃性の治療法 |
| WO2015195404A1 (en) | 2014-06-20 | 2015-12-23 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for detection of an analyte by movement of tethered microparticles |
| WO2016205239A1 (en) | 2015-06-15 | 2016-12-22 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | Non-hormonal mammalian sperm decoy contraception based on the n-terminus of the zp2 protein |
| CN110234600B (zh) | 2016-10-21 | 2023-03-21 | 美国政府(由卫生和人类服务部的部长所代表) | 分子纳米标签 |
| CN108976318B (zh) * | 2017-06-01 | 2021-03-30 | 首都医科大学 | 单-6-(生物素酰胺基)-6-脱氧-β-环糊精及其制备方法和应用 |
| WO2019133727A1 (en) | 2017-12-29 | 2019-07-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Universal influenza virus probe set for enrichment of any influenza virus nucleic acid |
| MX2022000343A (es) | 2019-07-09 | 2022-03-11 | Optimvia Llc | Metodos para sintetizar polisacaridos anticoagulantes. |
| WO2021075165A1 (ja) * | 2019-10-17 | 2021-04-22 | 株式会社オートネットワーク技術研究所 | 配線モジュール |
| WO2022056078A1 (en) | 2020-09-11 | 2022-03-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rnase h-assisted detection assay for rna (radar) |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3960884A (en) * | 1974-04-24 | 1976-06-01 | Sergei Ivanovich Zavyalov | Method of preparing racemic biotin |
| AU563351C (en) * | 1982-01-15 | 2003-06-19 | Glaxo Group Limited | Synthesis of oligosaccharides |
| IL102758A (en) * | 1991-08-23 | 1997-03-18 | Akzo Nv | Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them |
| US20010023288A1 (en) * | 1999-07-07 | 2001-09-20 | Wilbur D. Scott | Trifunctional reagent for conjugation to a biomolecule |
| FR2751334B1 (fr) * | 1996-07-19 | 1998-10-16 | Sanofi Sa | Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant |
| FR2773804B1 (fr) * | 1998-01-19 | 2000-02-18 | Sanofi Sa | Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant |
| FR2773801B1 (fr) * | 1998-01-19 | 2000-05-12 | Sanofi Sa | Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant |
| GB2335490B (en) * | 1998-03-20 | 2003-05-14 | Ortho Clinical Diagnostics | An assay surface that permits an analyte releasiing step |
| AU8366398A (en) * | 1998-07-07 | 2000-01-24 | Department Of Radiation Oncology University Of Washington | Trifunctional reagent for conjugation to a biomolecule |
| AU4933099A (en) | 1998-07-31 | 2000-02-21 | Seikagaku Corporation | Novel glycosaminoglycan and drug compositions containing the same |
| FR2814463B1 (fr) * | 2000-09-22 | 2002-11-15 | Sanofi Synthelabo | Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine |
-
2000
- 2000-09-22 FR FR0012094A patent/FR2814463B1/fr not_active Expired - Fee Related
-
2001
- 2001-09-20 EP EP01972171A patent/EP1322673B1/fr not_active Expired - Lifetime
- 2001-09-20 DE DE60130669T patent/DE60130669T2/de not_active Expired - Lifetime
- 2001-09-20 PT PT01972171T patent/PT1322673E/pt unknown
- 2001-09-20 ES ES01972171T patent/ES2292625T3/es not_active Expired - Lifetime
- 2001-09-20 UA UA2003021719A patent/UA79736C2/uk unknown
- 2001-09-20 CZ CZ20030814A patent/CZ300856B6/cs not_active IP Right Cessation
- 2001-09-20 AR ARP010104436A patent/AR030774A1/es not_active Application Discontinuation
- 2001-09-20 BR BR0114007-8A patent/BR0114007A/pt active Search and Examination
- 2001-09-20 GE GE5103A patent/GEP20053616B/en unknown
- 2001-09-20 SK SK5031-2009A patent/SK287218B6/sk not_active IP Right Cessation
- 2001-09-20 AU AU9196001A patent/AU9196001A/xx active Pending
- 2001-09-20 US US10/381,154 patent/US6844329B2/en not_active Expired - Lifetime
- 2001-09-20 KR KR1020087009747A patent/KR20080049139A/ko not_active Application Discontinuation
- 2001-09-20 IL IL15484801A patent/IL154848A0/xx unknown
- 2001-09-20 AU AU2001291960A patent/AU2001291960C1/en not_active Ceased
- 2001-09-20 ME MEP-236/08A patent/MEP23608A/xx unknown
- 2001-09-20 CA CA2418815A patent/CA2418815C/en not_active Expired - Fee Related
- 2001-09-20 ME MEP-2008-236A patent/ME00080B/me unknown
- 2001-09-20 CN CNB018161588A patent/CN1235914C/zh not_active Expired - Fee Related
- 2001-09-20 PL PL363368A patent/PL206727B1/pl unknown
- 2001-09-20 AT AT01972171T patent/ATE374215T1/de active
- 2001-09-20 WO PCT/FR2001/002918 patent/WO2002024754A1/fr active Application Filing
- 2001-09-20 JP JP2002529162A patent/JP5016778B2/ja not_active Expired - Fee Related
- 2001-09-20 SI SI200130786T patent/SI1322673T1/sl unknown
- 2001-09-20 EE EEP200300114A patent/EE05202B1/xx not_active IP Right Cessation
- 2001-09-20 SK SK356-2003A patent/SK287054B6/sk not_active IP Right Cessation
- 2001-09-20 HU HU0303551A patent/HUP0303551A3/hu not_active Application Discontinuation
- 2001-09-20 DK DK01972171T patent/DK1322673T3/da active
- 2001-09-20 MX MXPA03002483A patent/MXPA03002483A/es active IP Right Grant
- 2001-09-20 HU HUP1400034 patent/HU1400034D0/hu not_active Application Discontinuation
- 2001-09-20 NZ NZ524472A patent/NZ524472A/en not_active IP Right Cessation
- 2001-09-20 KR KR1020037004108A patent/KR100891388B1/ko not_active IP Right Cessation
- 2001-09-20 RS YUP-197/03A patent/RS50730B/sr unknown
- 2001-09-20 EA EA200300237A patent/EA005133B1/ru not_active IP Right Cessation
- 2001-09-21 PE PE2001000952A patent/PE20020471A1/es not_active Application Discontinuation
- 2001-09-21 TW TW090123340A patent/TWI308153B/zh not_active IP Right Cessation
-
2003
- 2003-02-28 ZA ZA200301692A patent/ZA200301692B/en unknown
- 2003-02-28 IS IS6733A patent/IS2550B/is unknown
- 2003-03-10 IL IL154848A patent/IL154848A/en not_active IP Right Cessation
- 2003-03-14 EC EC2003004514A patent/ECSP034514A/es unknown
- 2003-03-20 BG BG107650A patent/BG66191B1/bg unknown
- 2003-03-20 NO NO20031295A patent/NO332905B1/no not_active IP Right Cessation
- 2003-03-21 HR HR20030219A patent/HRP20030219B1/xx not_active IP Right Cessation
- 2003-08-05 HK HK03105615A patent/HK1053316A1/xx not_active IP Right Cessation
-
2005
- 2005-01-14 US US11/035,717 patent/US7943595B2/en not_active Expired - Fee Related
-
2007
- 2007-12-04 CY CY20071101542T patent/CY1108076T1/el unknown
-
2011
- 2011-02-28 US US13/036,143 patent/US8318696B2/en not_active Expired - Fee Related
- 2011-03-16 NO NO20110401A patent/NO20110401L/no not_active Application Discontinuation
-
2012
- 2012-02-10 JP JP2012027377A patent/JP2012131809A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20020471A1 (es) | Nuevos polisacaridos de actividad antitrombotica que presentan por lo menos un enlace covalente con la biotina o un derivado de la biotina | |
| BR0010242A (pt) | Composições quìmicas que atraem artrópodes | |
| FI892556A0 (fi) | Smoerjoljekompositioner och -koncentrat. | |
| AR011071A1 (es) | Metodo para fabricar una composicion detergente de bloque solido, composicion y detergente solido obtenidos por el metodo. | |
| BR9602187A (pt) | Processo de inibir a corrosão por ácido naftênico em um sistema de hidrocarboneto a alta temperatura | |
| ES2184070T3 (es) | Derivados de oximas sustituidas utiles como antagonistas de la neuroquinina. | |
| HN1997000118A (es) | 1,3, oxa thiolane nucleoside compuestos y composiciones | |
| EA200000843A1 (ru) | Сульфированные сахариды | |
| PT896533E (pt) | Pentafluorobenzenosulfonamidas e analogos | |
| ATE158016T1 (de) | Schmierfettzusammensetzungen | |
| ES2096872T3 (es) | Composiciones limpiadoras acuosas acidas. | |
| ES2046691T3 (es) | Metodo para lubrificar maquinas refrigeradoras. | |
| BR9713261A (pt) | Tricìclicos substituìdos | |
| DE69313751T2 (de) | Schmierfettzusammensetzungen | |
| FI911512A (fi) | Oeverbasiska calixarater, foerfarande foer deras framstaellning, kompositioner innehaollande desamma och deras anvaendning som tillsatsaemnen i smoerjaemnen. | |
| MX173310B (es) | Derivados fenolicos de benzotiazol como inhibidores de la corrosion | |
| ES2091236T3 (es) | Composiciones de lubricantes. | |
| GT200000049A (es) | Compuestos quimicos. | |
| ES2145064T3 (es) | Compuestos de penem sustituidos con metileno en posicion 6 y productos intermedios. | |
| ES2043725T3 (es) | Aminofenil-carbamatos substituidos. | |
| BR9001734A (pt) | Composto inseticida de diamino-etileno,processo para sua preparacao e composicao inseticida que o contem | |
| MX9203360A (es) | Derivados de hexahidroazepinas y composiciones farmaceuticas que los contienen. | |
| BR0012242A (pt) | Composição de óleo para máquina de refrigeração | |
| MX168469B (es) | Procedimiento para la preparacion de derivados aminoalcoholes acilados | |
| SE8207224D0 (sv) | Nouveaux derives aminoalkoxy aromatiques, leur procede de preparation et leur application en therapeutique |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |