OA12540A - Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes. - Google Patents

Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes. Download PDF

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Publication number
OA12540A
OA12540A OA1200300175A OA1200300175A OA12540A OA 12540 A OA12540 A OA 12540A OA 1200300175 A OA1200300175 A OA 1200300175A OA 1200300175 A OA1200300175 A OA 1200300175A OA 12540 A OA12540 A OA 12540A
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OA
OAPI
Prior art keywords
formula
group
alkyl
fluoro
biphenyl
Prior art date
Application number
OA1200300175A
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English (en)
Inventor
Robert James Chambers
Thomas Victor Magee
Anthony Marfat
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Pfizer Prod Inc
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Publication of OA12540A publication Critical patent/OA12540A/en

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
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OA1200300175A 2001-01-31 2001-12-06 Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes. OA12540A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26549201P 2001-01-31 2001-01-31

Publications (1)

Publication Number Publication Date
OA12540A true OA12540A (en) 2006-06-05

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ID=23010671

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200300175A OA12540A (en) 2001-01-31 2001-12-06 Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes.

Country Status (25)

Country Link
US (2) US6649633B2 (zh)
EP (1) EP1355884A1 (zh)
JP (1) JP2004520386A (zh)
KR (1) KR20030074761A (zh)
CN (1) CN1518542A (zh)
BG (1) BG108038A (zh)
BR (1) BR0116852A (zh)
CA (1) CA2436535A1 (zh)
CR (1) CR7025A (zh)
CZ (1) CZ20031895A3 (zh)
EA (1) EA200300621A1 (zh)
EC (2) ECSP034709A (zh)
EE (1) EE200300360A (zh)
HU (1) HUP0400637A2 (zh)
IL (1) IL156413A0 (zh)
IS (1) IS6846A (zh)
MA (1) MA26983A1 (zh)
MX (1) MXPA03006887A (zh)
NO (1) NO20033397L (zh)
NZ (1) NZ526453A (zh)
OA (1) OA12540A (zh)
PL (1) PL364135A1 (zh)
SK (1) SK8792003A3 (zh)
WO (1) WO2002060875A1 (zh)
ZA (1) ZA200304894B (zh)

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