OA11841A - 2-Aminopyridines containing fused ring substituents. - Google Patents

2-Aminopyridines containing fused ring substituents. Download PDF

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Publication number
OA11841A
OA11841A OA1200100224A OA1200100224A OA11841A OA 11841 A OA11841 A OA 11841A OA 1200100224 A OA1200100224 A OA 1200100224A OA 1200100224 A OA1200100224 A OA 1200100224A OA 11841 A OA11841 A OA 11841A
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group
disorder
disorders
ring
alkyl
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OA1200100224A
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English (en)
Inventor
Lowe John Adams Iii
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Pfizer Prod Inc
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Publication of OA11841A publication Critical patent/OA11841A/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61P9/00Drugs for disorders of the cardiovascular system
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
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OA1200100224A 1999-02-25 2000-02-02 2-Aminopyridines containing fused ring substituents. OA11841A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12159799P 1999-02-25 1999-02-25

Publications (1)

Publication Number Publication Date
OA11841A true OA11841A (en) 2005-08-22

Family

ID=22397690

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200100224A OA11841A (en) 1999-02-25 2000-02-02 2-Aminopyridines containing fused ring substituents.

Country Status (44)

Country Link
US (2) US6211208B1 (de)
EP (1) EP1155000B1 (de)
JP (1) JP3825636B2 (de)
KR (1) KR20010114213A (de)
CN (1) CN1341099A (de)
AP (1) AP2001002251A0 (de)
AR (1) AR018979A1 (de)
AT (1) ATE245143T1 (de)
AU (1) AU767593B2 (de)
BG (1) BG105855A (de)
BR (1) BR0008569A (de)
CA (1) CA2364719C (de)
CO (1) CO5160241A1 (de)
CR (1) CR6438A (de)
CZ (1) CZ20013036A3 (de)
DE (1) DE60003893T2 (de)
DK (1) DK1155000T3 (de)
DZ (1) DZ3017A1 (de)
EA (1) EA003941B1 (de)
EE (1) EE200100454A (de)
ES (1) ES2200813T3 (de)
GT (1) GT200000021A (de)
HN (1) HN2000000016A (de)
HR (1) HRP20010597A2 (de)
HU (1) HUP0200163A3 (de)
ID (1) ID29892A (de)
IL (1) IL144308A0 (de)
IS (1) IS6005A (de)
MA (1) MA26721A1 (de)
MX (1) MXPA01008671A (de)
NO (1) NO20014095L (de)
NZ (1) NZ512912A (de)
OA (1) OA11841A (de)
PA (1) PA8490901A1 (de)
PE (1) PE20001482A1 (de)
PL (1) PL350219A1 (de)
PT (1) PT1155000E (de)
SK (1) SK12022001A3 (de)
SV (1) SV2002000026A (de)
TN (1) TNSN00034A1 (de)
TR (1) TR200102481T2 (de)
WO (1) WO2000050400A1 (de)
YU (1) YU58301A (de)
ZA (1) ZA200106974B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049379A1 (en) * 1997-08-27 2001-12-06 Lowe John Adams 2-aminopyridines containing fused ring substituents
IL144308A0 (en) * 1999-02-25 2002-05-23 Pfizer Prod Inc 2-aminopyridines containing fused ring substituents
BR0109706A (pt) 2000-03-31 2003-02-04 Euro Celtique Sa Aminopiridinas e seus usos como anticonvulsivantes e bloqueadores dos canais de sódio
US20040092741A1 (en) * 2002-11-08 2004-05-13 Pfizer Inc Substituted pyridines via boronic acid coupling
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
WO2004052291A2 (en) * 2002-12-06 2004-06-24 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
WO2014138460A1 (en) 2013-03-07 2014-09-12 Northwestern University 2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors
US10759791B2 (en) 2014-11-04 2020-09-01 Northwestern University Mammalian and bacterial nitric oxide synthase inhibitors
EP3215497A4 (de) 2014-11-04 2018-11-07 Northwestern University Säugetier- und bakterielle stickoxid-synthaseinhibitoren
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
US12213973B2 (en) 2021-10-18 2025-02-04 Northwestern University Bacterial nitric oxide synthase inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4515696A (en) * 1994-12-12 1996-07-03 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
JPH101435A (ja) * 1995-09-14 1998-01-06 Nippon Kayaku Co Ltd 2−アミノピリジン類を有効成分とする一酸化窒素合成酵素阻害剤
EP0891332B1 (de) * 1996-03-29 2004-03-17 Pfizer Inc. 6-phenylpyridinderivate
HN1997000027A (es) 1996-12-06 1997-06-05 Pfizer Prod Inc Derivados de 6-fenil piridil - 2 amina
SK101199A3 (en) * 1997-02-10 2000-10-09 Pfizer Prod Inc 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines, their use and pharmaceutical compositions based thereupon
HN1998000118A (es) * 1997-08-27 1999-02-09 Pfizer Prod Inc 2 - aminopiridinas que contienen sustituyentes de anillos condensados.
HN1998000125A (es) * 1997-08-28 1999-02-09 Pfizer Prod Inc 2-aminopiridinas con sustituyentes alcoxi ramificados
EA003991B1 (ru) * 1998-06-03 2003-12-25 Пфайзер Продактс Инк. Производные 2-аминопиридинов, способ ингибирования синтазы оксида азота, фармацевтические композиции и способы лечения
IL144308A0 (en) * 1999-02-25 2002-05-23 Pfizer Prod Inc 2-aminopyridines containing fused ring substituents

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IS6005A (is) 2001-07-13
CN1341099A (zh) 2002-03-20
EA003941B1 (ru) 2003-10-30
MA26721A1 (fr) 2004-12-20
KR20010114213A (ko) 2001-12-31
CA2364719A1 (en) 2000-08-31
AU2124300A (en) 2000-09-14
ATE245143T1 (de) 2003-08-15
AU767593B2 (en) 2003-11-20
TR200102481T2 (tr) 2002-01-21
PA8490901A1 (es) 2001-04-30
US6211208B1 (en) 2001-04-03
EP1155000A1 (de) 2001-11-21
ZA200106974B (en) 2002-10-14
NZ512912A (en) 2003-07-25
DE60003893D1 (de) 2003-08-21
AR018979A1 (es) 2001-12-12
TNSN00034A1 (fr) 2005-11-10
BR0008569A (pt) 2002-01-22
HRP20010597A2 (en) 2002-08-31
DZ3017A1 (fr) 2004-03-20
JP2002537381A (ja) 2002-11-05
ID29892A (id) 2001-10-18
US6372768B2 (en) 2002-04-16
PL350219A1 (en) 2002-11-18
EA200100816A1 (ru) 2001-12-24
WO2000050400A1 (en) 2000-08-31
CA2364719C (en) 2006-07-04
SK12022001A3 (sk) 2002-07-02
GT200000021A (es) 2001-08-17
NO20014095D0 (no) 2001-08-23
HUP0200163A3 (en) 2002-11-28
CR6438A (es) 2004-02-23
BG105855A (en) 2002-04-30
HUP0200163A2 (en) 2002-06-29
DK1155000T3 (da) 2003-10-13
NO20014095L (no) 2001-10-24
PE20001482A1 (es) 2001-01-03
SV2002000026A (es) 2002-02-05
HN2000000016A (es) 2001-02-02
EP1155000B1 (de) 2003-07-16
EE200100454A (et) 2002-12-16
JP3825636B2 (ja) 2006-09-27
US20010014689A1 (en) 2001-08-16
ES2200813T3 (es) 2004-03-16
PT1155000E (pt) 2003-10-31
AP2001002251A0 (en) 2001-09-30
MXPA01008671A (es) 2002-03-14
YU58301A (sh) 2004-05-12
DE60003893T2 (de) 2004-02-05
IL144308A0 (en) 2002-05-23
CZ20013036A3 (cs) 2002-03-13
CO5160241A1 (es) 2002-05-30

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