DK1155000T3 - 2-aminopyridiner som indeholder sammensluttede ringsubstituenser - Google Patents

2-aminopyridiner som indeholder sammensluttede ringsubstituenser

Info

Publication number
DK1155000T3
DK1155000T3 DK00901285T DK00901285T DK1155000T3 DK 1155000 T3 DK1155000 T3 DK 1155000T3 DK 00901285 T DK00901285 T DK 00901285T DK 00901285 T DK00901285 T DK 00901285T DK 1155000 T3 DK1155000 T3 DK 1155000T3
Authority
DK
Denmark
Prior art keywords
ring substituents
linked ring
containing linked
aminopyridines containing
aminopyridines
Prior art date
Application number
DK00901285T
Other languages
English (en)
Inventor
John Adams Lowe Iii
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of DK1155000T3 publication Critical patent/DK1155000T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
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    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
DK00901285T 1999-02-25 2000-02-02 2-aminopyridiner som indeholder sammensluttede ringsubstituenser DK1155000T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12159799P 1999-02-25 1999-02-25
PCT/IB2000/000109 WO2000050400A1 (en) 1999-02-25 2000-02-02 2-aminopyridines containing fused ring substituents

Publications (1)

Publication Number Publication Date
DK1155000T3 true DK1155000T3 (da) 2003-10-13

Family

ID=22397690

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00901285T DK1155000T3 (da) 1999-02-25 2000-02-02 2-aminopyridiner som indeholder sammensluttede ringsubstituenser

Country Status (44)

Country Link
US (2) US6211208B1 (da)
EP (1) EP1155000B1 (da)
JP (1) JP3825636B2 (da)
KR (1) KR20010114213A (da)
CN (1) CN1341099A (da)
AP (1) AP2001002251A0 (da)
AR (1) AR018979A1 (da)
AT (1) ATE245143T1 (da)
AU (1) AU767593B2 (da)
BG (1) BG105855A (da)
BR (1) BR0008569A (da)
CA (1) CA2364719C (da)
CO (1) CO5160241A1 (da)
CR (1) CR6438A (da)
CZ (1) CZ20013036A3 (da)
DE (1) DE60003893T2 (da)
DK (1) DK1155000T3 (da)
DZ (1) DZ3017A1 (da)
EA (1) EA003941B1 (da)
EE (1) EE200100454A (da)
ES (1) ES2200813T3 (da)
GT (1) GT200000021A (da)
HN (1) HN2000000016A (da)
HR (1) HRP20010597A2 (da)
HU (1) HUP0200163A3 (da)
ID (1) ID29892A (da)
IL (1) IL144308A0 (da)
IS (1) IS6005A (da)
MA (1) MA26721A1 (da)
MX (1) MXPA01008671A (da)
NO (1) NO20014095L (da)
NZ (1) NZ512912A (da)
OA (1) OA11841A (da)
PA (1) PA8490901A1 (da)
PE (1) PE20001482A1 (da)
PL (1) PL350219A1 (da)
PT (1) PT1155000E (da)
SK (1) SK12022001A3 (da)
SV (1) SV2002000026A (da)
TN (1) TNSN00034A1 (da)
TR (1) TR200102481T2 (da)
WO (1) WO2000050400A1 (da)
YU (1) YU58301A (da)
ZA (1) ZA200106974B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049379A1 (en) * 1997-08-27 2001-12-06 Lowe John Adams 2-aminopyridines containing fused ring substituents
ES2200813T3 (es) * 1999-02-25 2004-03-16 Pfizer Products Inc. 2-aminopiridinas que contienen sustituyentes de anillo condesado.
IL151952A0 (en) 2000-03-31 2003-04-10 Euro Celtique Sa Aminopyridine derivatives and pharmaceutical compositions containing the same
US20040092741A1 (en) * 2002-11-08 2004-05-13 Pfizer Inc Substituted pyridines via boronic acid coupling
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
WO2004052291A2 (en) * 2002-12-06 2004-06-24 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
US9120750B2 (en) 2013-03-07 2015-09-01 Northwestern University 2-Aminopyridine-based selective neuronal nitric oxide synthase inhibitors
US10759791B2 (en) 2014-11-04 2020-09-01 Northwestern University Mammalian and bacterial nitric oxide synthase inhibitors
US9951014B2 (en) 2014-11-04 2018-04-24 Northwestern University Mammalian and bacterial nitric oxide synthase inhibitors
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996018616A1 (en) * 1994-12-12 1996-06-20 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
JPH101435A (ja) * 1995-09-14 1998-01-06 Nippon Kayaku Co Ltd ２−アミノピリジン類を有効成分とする一酸化窒素合成酵素阻害剤
EP1471055A1 (en) * 1996-03-29 2004-10-27 Pfizer Inc. 6-phenylpyridyl-2-amine derivatives
HN1997000027A (es) 1996-12-06 1997-06-05 Pfizer Prod Inc Derivados de 6-fenil piridil - 2 amina
AU744313B2 (en) * 1997-02-10 2002-02-21 Pfizer Products Inc. 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines
HN1998000118A (es) * 1997-08-27 1999-02-09 Pfizer Prod Inc 2 - aminopiridinas que contienen sustituyentes de anillos condensados.
HN1998000125A (es) * 1997-08-28 1999-02-09 Pfizer Prod Inc 2-aminopiridinas con sustituyentes alcoxi ramificados
CN1303379A (zh) * 1998-06-03 2001-07-11 辉瑞产品公司 作为氧化氮合酶抑制剂的含稠环取代基的2－氨基吡啶
ES2200813T3 (es) * 1999-02-25 2004-03-16 Pfizer Products Inc. 2-aminopiridinas que contienen sustituyentes de anillo condesado.

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DZ3017A1 (fr) 2004-03-20
ZA200106974B (en) 2002-10-14
US6211208B1 (en) 2001-04-03
NO20014095D0 (no) 2001-08-23
AU767593B2 (en) 2003-11-20
HUP0200163A2 (en) 2002-06-29
NO20014095L (no) 2001-10-24
OA11841A (en) 2005-08-22
IL144308A0 (en) 2002-05-23
US6372768B2 (en) 2002-04-16
CR6438A (es) 2004-02-23
AP2001002251A0 (en) 2001-09-30
PT1155000E (pt) 2003-10-31
EA200100816A1 (ru) 2001-12-24
KR20010114213A (ko) 2001-12-31
AR018979A1 (es) 2001-12-12
TR200102481T2 (tr) 2002-01-21
BG105855A (en) 2002-04-30
IS6005A (is) 2001-07-13
PA8490901A1 (es) 2001-04-30
EP1155000B1 (en) 2003-07-16
HRP20010597A2 (en) 2002-08-31
JP3825636B2 (ja) 2006-09-27
MA26721A1 (fr) 2004-12-20
ID29892A (id) 2001-10-18
PL350219A1 (en) 2002-11-18
NZ512912A (en) 2003-07-25
HUP0200163A3 (en) 2002-11-28
AU2124300A (en) 2000-09-14
ATE245143T1 (de) 2003-08-15
EE200100454A (et) 2002-12-16
CZ20013036A3 (cs) 2002-03-13
EP1155000A1 (en) 2001-11-21
ES2200813T3 (es) 2004-03-16
MXPA01008671A (es) 2002-03-14
US20010014689A1 (en) 2001-08-16
CO5160241A1 (es) 2002-05-30
BR0008569A (pt) 2002-01-22
EA003941B1 (ru) 2003-10-30
SK12022001A3 (sk) 2002-07-02
WO2000050400A1 (en) 2000-08-31
DE60003893D1 (de) 2003-08-21
SV2002000026A (es) 2002-02-05
HN2000000016A (es) 2001-02-02
CA2364719C (en) 2006-07-04
GT200000021A (es) 2001-08-17
CA2364719A1 (en) 2000-08-31
JP2002537381A (ja) 2002-11-05
DE60003893T2 (de) 2004-02-05
TNSN00034A1 (fr) 2005-11-10
PE20001482A1 (es) 2001-01-03
YU58301A (sh) 2004-05-12
CN1341099A (zh) 2002-03-20

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