BG105855A - 2-aminopyridines containing fused ring substituents - Google Patents

2-aminopyridines containing fused ring substituents

Info

Publication number
BG105855A
BG105855A BG105855A BG10585501A BG105855A BG 105855 A BG105855 A BG 105855A BG 105855 A BG105855 A BG 105855A BG 10585501 A BG10585501 A BG 10585501A BG 105855 A BG105855 A BG 105855A
Authority
BG
Bulgaria
Prior art keywords
group
alkyl
ring
aryl
aralkyl
Prior art date
Application number
BG105855A
Other languages
Bulgarian (bg)
English (en)
Inventor
John Adams Lowe
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of BG105855A publication Critical patent/BG105855A/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
BG105855A 1999-02-25 2001-08-30 2-aminopyridines containing fused ring substituents BG105855A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12159799P 1999-02-25 1999-02-25
PCT/IB2000/000109 WO2000050400A1 (en) 1999-02-25 2000-02-02 2-aminopyridines containing fused ring substituents

Publications (1)

Publication Number Publication Date
BG105855A true BG105855A (en) 2002-04-30

Family

ID=22397690

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105855A BG105855A (en) 1999-02-25 2001-08-30 2-aminopyridines containing fused ring substituents

Country Status (44)

Country Link
US (2) US6211208B1 (xx)
EP (1) EP1155000B1 (xx)
JP (1) JP3825636B2 (xx)
KR (1) KR20010114213A (xx)
CN (1) CN1341099A (xx)
AP (1) AP2001002251A0 (xx)
AR (1) AR018979A1 (xx)
AT (1) ATE245143T1 (xx)
AU (1) AU767593B2 (xx)
BG (1) BG105855A (xx)
BR (1) BR0008569A (xx)
CA (1) CA2364719C (xx)
CO (1) CO5160241A1 (xx)
CR (1) CR6438A (xx)
CZ (1) CZ20013036A3 (xx)
DE (1) DE60003893T2 (xx)
DK (1) DK1155000T3 (xx)
DZ (1) DZ3017A1 (xx)
EA (1) EA003941B1 (xx)
EE (1) EE200100454A (xx)
ES (1) ES2200813T3 (xx)
GT (1) GT200000021A (xx)
HN (1) HN2000000016A (xx)
HR (1) HRP20010597A2 (xx)
HU (1) HUP0200163A3 (xx)
ID (1) ID29892A (xx)
IL (1) IL144308A0 (xx)
IS (1) IS6005A (xx)
MA (1) MA26721A1 (xx)
MX (1) MXPA01008671A (xx)
NO (1) NO20014095L (xx)
NZ (1) NZ512912A (xx)
OA (1) OA11841A (xx)
PA (1) PA8490901A1 (xx)
PE (1) PE20001482A1 (xx)
PL (1) PL350219A1 (xx)
PT (1) PT1155000E (xx)
SK (1) SK12022001A3 (xx)
SV (1) SV2002000026A (xx)
TN (1) TNSN00034A1 (xx)
TR (1) TR200102481T2 (xx)
WO (1) WO2000050400A1 (xx)
YU (1) YU58301A (xx)
ZA (1) ZA200106974B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049379A1 (en) * 1997-08-27 2001-12-06 Lowe John Adams 2-aminopyridines containing fused ring substituents
PT1155000E (pt) * 1999-02-25 2003-10-31 Pfizer Prod Inc 2-aminopiridinas contendo aneis fundidos substituintes
NZ521870A (en) 2000-03-31 2004-08-27 Euro Celtique S Aminopyridines and their use as anticonvulsants and sodium channel blockers
US20040092741A1 (en) * 2002-11-08 2004-05-13 Pfizer Inc Substituted pyridines via boronic acid coupling
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
EP1567497B1 (en) * 2002-12-06 2009-09-23 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
US9120750B2 (en) 2013-03-07 2015-09-01 Northwestern University 2-Aminopyridine-based selective neuronal nitric oxide synthase inhibitors
US10759791B2 (en) 2014-11-04 2020-09-01 Northwestern University Mammalian and bacterial nitric oxide synthase inhibitors
US9951014B2 (en) 2014-11-04 2018-04-24 Northwestern University Mammalian and bacterial nitric oxide synthase inhibitors
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4515696A (en) * 1994-12-12 1996-07-03 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
JPH101435A (ja) * 1995-09-14 1998-01-06 Nippon Kayaku Co Ltd ２−アミノピリジン類を有効成分とする一酸化窒素合成酵素阻害剤
ATE261942T1 (de) * 1996-03-29 2004-04-15 Pfizer 6-phenylpyridinderivate
HN1997000027A (es) 1996-12-06 1997-06-05 Pfizer Prod Inc Derivados de 6-fenil piridil - 2 amina
UA64740C2 (uk) * 1997-02-10 2004-03-15 Пфайзер Продактс Інк. Похідні 2-амінопіридинів, фармацевтична композиція на їх основі (варіанти), спосіб лікування (варіанти), спосіб інгібування nos у ссавця та проміжні сполуки (варіанти)
HN1998000118A (es) * 1997-08-27 1999-02-09 Pfizer Prod Inc 2 - aminopiridinas que contienen sustituyentes de anillos condensados.
HN1998000125A (es) * 1997-08-28 1999-02-09 Pfizer Prod Inc 2-aminopiridinas con sustituyentes alcoxi ramificados
DE69923448T2 (de) * 1998-06-03 2005-12-29 Pfizer Products Inc., Groton 2-aminopyridine mit kondensierten ringsubstituenten als stickstoff-oxid-synthase inhibitoren
PT1155000E (pt) * 1999-02-25 2003-10-31 Pfizer Prod Inc 2-aminopiridinas contendo aneis fundidos substituintes

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DE60003893T2 (de) 2004-02-05
MXPA01008671A (es) 2002-03-14
NO20014095L (no) 2001-10-24
TR200102481T2 (tr) 2002-01-21
US20010014689A1 (en) 2001-08-16
CR6438A (es) 2004-02-23
EA003941B1 (ru) 2003-10-30
HRP20010597A2 (en) 2002-08-31
EP1155000A1 (en) 2001-11-21
TNSN00034A1 (fr) 2005-11-10
DK1155000T3 (da) 2003-10-13
DE60003893D1 (de) 2003-08-21
CA2364719A1 (en) 2000-08-31
EP1155000B1 (en) 2003-07-16
SV2002000026A (es) 2002-02-05
ID29892A (id) 2001-10-18
ATE245143T1 (de) 2003-08-15
AU767593B2 (en) 2003-11-20
JP3825636B2 (ja) 2006-09-27
CZ20013036A3 (cs) 2002-03-13
OA11841A (en) 2005-08-22
PL350219A1 (en) 2002-11-18
PE20001482A1 (es) 2001-01-03
HN2000000016A (es) 2001-02-02
NZ512912A (en) 2003-07-25
EA200100816A1 (ru) 2001-12-24
GT200000021A (es) 2001-08-17
NO20014095D0 (no) 2001-08-23
CO5160241A1 (es) 2002-05-30
CA2364719C (en) 2006-07-04
AP2001002251A0 (en) 2001-09-30
EE200100454A (et) 2002-12-16
HUP0200163A2 (en) 2002-06-29
DZ3017A1 (fr) 2004-03-20
ES2200813T3 (es) 2004-03-16
KR20010114213A (ko) 2001-12-31
AU2124300A (en) 2000-09-14
WO2000050400A1 (en) 2000-08-31
BR0008569A (pt) 2002-01-22
JP2002537381A (ja) 2002-11-05
US6211208B1 (en) 2001-04-03
PA8490901A1 (es) 2001-04-30
US6372768B2 (en) 2002-04-16
IL144308A0 (en) 2002-05-23
MA26721A1 (fr) 2004-12-20
PT1155000E (pt) 2003-10-31
ZA200106974B (en) 2002-10-14
SK12022001A3 (sk) 2002-07-02
CN1341099A (zh) 2002-03-20
YU58301A (sh) 2004-05-12
AR018979A1 (es) 2001-12-12
IS6005A (is) 2001-07-13
HUP0200163A3 (en) 2002-11-28

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