OA08241A - Procédé de préparation du chlorhydrate de phényl-1 diéthylamino carbonyl-1 aminométhyl-2 cyclopropane (Z). - Google Patents
Procédé de préparation du chlorhydrate de phényl-1 diéthylamino carbonyl-1 aminométhyl-2 cyclopropane (Z).Info
- Publication number
- OA08241A OA08241A OA58846A OA58846A OA08241A OA 08241 A OA08241 A OA 08241A OA 58846 A OA58846 A OA 58846A OA 58846 A OA58846 A OA 58846A OA 08241 A OA08241 A OA 08241A
- Authority
- OA
- OAPI
- Prior art keywords
- aminomethyl
- phenyl
- preparation
- diethylamino carbonyl
- cyclopropane hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8506335A FR2581059B1 (fr) | 1985-04-25 | 1985-04-25 | Procede de preparation du chlorhydrate de phenyl-1 diethyl amino carbonyl-1 aminomethyl-2 cyclopropane (z) |
Publications (1)
Publication Number | Publication Date |
---|---|
OA08241A true OA08241A (fr) | 1987-10-30 |
Family
ID=9318686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA58846A OA08241A (fr) | 1985-04-25 | 1986-04-25 | Procédé de préparation du chlorhydrate de phényl-1 diéthylamino carbonyl-1 aminométhyl-2 cyclopropane (Z). |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP0200638B1 (el) |
JP (1) | JPS61251650A (el) |
KR (1) | KR940006764B1 (el) |
AR (1) | AR240695A1 (el) |
AT (1) | ATE42273T1 (el) |
AU (1) | AU587613B2 (el) |
CA (1) | CA1266486A (el) |
DE (1) | DE3662877D1 (el) |
DK (1) | DK170888B1 (el) |
ES (1) | ES8704449A1 (el) |
FI (1) | FI87196C (el) |
FR (1) | FR2581059B1 (el) |
GE (1) | GEP19970789B (el) |
GR (1) | GR860980B (el) |
HU (1) | HU195182B (el) |
IE (1) | IE59015B1 (el) |
MX (1) | MX162896B (el) |
NO (1) | NO165143C (el) |
OA (1) | OA08241A (el) |
PT (1) | PT82461B (el) |
SU (1) | SU1443797A3 (el) |
YU (1) | YU44915B (el) |
ZA (1) | ZA862929B (el) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2640972B1 (el) * | 1988-12-28 | 1991-04-19 | Pf Medicament | |
US5621142A (en) * | 1994-02-22 | 1997-04-15 | Asahi Kasei Kogyo Kabushiki Kaisha | Aminoalkylcyclopropane derivatives |
FR2752732B1 (fr) * | 1996-08-28 | 1998-11-20 | Pf Medicament | Forme galenique a liberation prolongee de milnacipran |
JP4418717B2 (ja) | 2004-06-24 | 2010-02-24 | 住友化学株式会社 | (z)−1−フェニル−1−ジエチルアミノカルボニル−2−アミノメチルシクロプロパン塩酸塩の製造方法 |
JP4828863B2 (ja) * | 2005-01-28 | 2011-11-30 | 住友化学株式会社 | (z)−1−フェニル−1−(n,n−ジエチルアミノカルボニル)−2−フタルイミドメチルシクロプロパンの製造方法 |
US8309128B2 (en) | 2005-06-10 | 2012-11-13 | Pierre Fabre Medicament | Stabilized milnacipran formulation |
KR100772244B1 (ko) * | 2005-07-20 | 2007-11-01 | 안국약품 주식회사 | 밀나시프란염산염의 제조방법 |
JP5338035B2 (ja) * | 2006-04-17 | 2013-11-13 | 住友化学株式会社 | 多環式ラクタム類の製造方法 |
US20090118519A1 (en) * | 2006-04-17 | 2009-05-07 | Sumitomo Chemical Company, Limited | Production Method of Polycyclic Lactams |
EP2114868A2 (en) * | 2007-02-28 | 2009-11-11 | Ranbaxy Laboratories Limited | Novel polymorphic forms of milnacipran hydrochloride |
FR2941454B1 (fr) | 2009-01-29 | 2011-04-01 | Pf Medicament | Proced de synthese du (1s,2r)-milnacipran |
US20100274050A1 (en) * | 2009-04-23 | 2010-10-28 | Glenmark Generics Limited | Solid milnacipran and process for the preparation of the same |
WO2012145234A2 (en) | 2011-04-21 | 2012-10-26 | Emory University | Cyclopropyl derivatives and methods of use |
CN103242289B (zh) * | 2012-02-03 | 2015-01-07 | 暨明医药科技(苏州)有限公司 | N,n-二烯丙基-(1r, 2r)-2-胺甲基-1-(2-噻吩)环丙烷酰胺盐酸盐的制备方法 |
WO2014009767A1 (en) | 2012-07-07 | 2014-01-16 | Micro Labs Limited | An improved process for the preparation of 1-aryl 2-aminomethyl cyclopropane carboxyamide (z) derivatives, their isomers and salts |
EP2906518A4 (en) | 2012-10-09 | 2016-07-27 | California Inst Of Techn | CYCLOPROPANATION OF OLEFIN IN VIVO AND IN VITRO CATALYZED BY ENZYMES HEMMES |
FR2998892B1 (fr) * | 2012-12-04 | 2015-01-02 | Pf Medicament | Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments |
CN103613513B (zh) * | 2013-12-09 | 2016-01-20 | 上海现代制药股份有限公司 | 盐酸米那普仑中间体及其制备方法和应用 |
US9399762B2 (en) | 2014-02-18 | 2016-07-26 | California Institute Of Technology | Methods and systems for sulfimidation or sulfoximidation of organic molecules |
CN104058992A (zh) * | 2014-06-13 | 2014-09-24 | 上海现代制药股份有限公司 | 左旋米那普仑盐酸盐的晶型 |
EP3230258B1 (en) | 2014-11-04 | 2019-06-26 | Química Sintética, S.A. | Process for the preparation of (1s,2r)-milnacipran |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2508035A1 (fr) * | 1981-06-23 | 1982-12-24 | Fabre Sa Pierre | Derives d'aryl-1-aminomethyl-2 cyclopropanes carboxamides (z), leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central |
-
1985
- 1985-04-25 FR FR8506335A patent/FR2581059B1/fr not_active Expired
-
1986
- 1986-04-14 GR GR860980A patent/GR860980B/el unknown
- 1986-04-17 AU AU56343/86A patent/AU587613B2/en not_active Expired
- 1986-04-18 ZA ZA862929A patent/ZA862929B/xx unknown
- 1986-04-21 IE IE105786A patent/IE59015B1/en not_active IP Right Cessation
- 1986-04-22 NO NO861573A patent/NO165143C/no unknown
- 1986-04-22 EP EP86400873A patent/EP0200638B1/fr not_active Expired
- 1986-04-22 DE DE8686400873T patent/DE3662877D1/de not_active Expired
- 1986-04-22 AT AT86400873T patent/ATE42273T1/de not_active IP Right Cessation
- 1986-04-22 YU YU655/86A patent/YU44915B/xx unknown
- 1986-04-23 CA CA000507320A patent/CA1266486A/fr not_active Expired - Lifetime
- 1986-04-23 KR KR1019860003133A patent/KR940006764B1/ko not_active IP Right Cessation
- 1986-04-24 HU HU861711A patent/HU195182B/hu unknown
- 1986-04-24 PT PT82461A patent/PT82461B/pt unknown
- 1986-04-24 ES ES554321A patent/ES8704449A1/es not_active Expired
- 1986-04-24 DK DK191286A patent/DK170888B1/da not_active IP Right Cessation
- 1986-04-24 JP JP61095850A patent/JPS61251650A/ja active Granted
- 1986-04-24 SU SU864027356A patent/SU1443797A3/ru active
- 1986-04-24 MX MX2307A patent/MX162896B/es unknown
- 1986-04-25 FI FI861755A patent/FI87196C/fi not_active IP Right Cessation
- 1986-04-25 AR AR30375986A patent/AR240695A1/es active
- 1986-04-25 OA OA58846A patent/OA08241A/xx unknown
-
1993
- 1993-03-04 GE GEAP1993566A patent/GEP19970789B/en unknown
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