DK191286A - Fremgangsmaade til fremstilling af hydrochloridt af 1-phenyl-1-diethylaminocarbonyl-2-aminomethyl-cyclopropan(z) - Google Patents
Fremgangsmaade til fremstilling af hydrochloridt af 1-phenyl-1-diethylaminocarbonyl-2-aminomethyl-cyclopropan(z) Download PDFInfo
- Publication number
- DK191286A DK191286A DK191286A DK191286A DK191286A DK 191286 A DK191286 A DK 191286A DK 191286 A DK191286 A DK 191286A DK 191286 A DK191286 A DK 191286A DK 191286 A DK191286 A DK 191286A
- Authority
- DK
- Denmark
- Prior art keywords
- diethylaminocarbonyl
- cyclopropane
- aminomethyl
- phenyl
- preparing hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8506335A FR2581059B1 (fr) | 1985-04-25 | 1985-04-25 | Procede de preparation du chlorhydrate de phenyl-1 diethyl amino carbonyl-1 aminomethyl-2 cyclopropane (z) |
| FR8506335 | 1985-04-25 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK191286D0 DK191286D0 (da) | 1986-04-24 |
| DK191286A true DK191286A (da) | 1986-10-26 |
| DK170888B1 DK170888B1 (da) | 1996-03-04 |
Family
ID=9318686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK191286A DK170888B1 (da) | 1985-04-25 | 1986-04-24 | Fremgangsmåde til fremstilling af hydrochloridt af 1-phenyl-1-di-ethylaminocarbonyl-2-aminomethyl-cyclopropan (Z) |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0200638B1 (da) |
| JP (1) | JPS61251650A (da) |
| KR (1) | KR940006764B1 (da) |
| AR (1) | AR240695A1 (da) |
| AT (1) | ATE42273T1 (da) |
| AU (1) | AU587613B2 (da) |
| CA (1) | CA1266486A (da) |
| DE (1) | DE3662877D1 (da) |
| DK (1) | DK170888B1 (da) |
| ES (1) | ES8704449A1 (da) |
| FI (1) | FI87196C (da) |
| FR (1) | FR2581059B1 (da) |
| GE (1) | GEP19970789B (da) |
| GR (1) | GR860980B (da) |
| HU (1) | HU195182B (da) |
| IE (1) | IE59015B1 (da) |
| MX (1) | MX162896B (da) |
| NO (1) | NO165143C (da) |
| OA (1) | OA08241A (da) |
| PT (1) | PT82461B (da) |
| SU (1) | SU1443797A3 (da) |
| YU (1) | YU44915B (da) |
| ZA (1) | ZA862929B (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2640972B1 (da) * | 1988-12-28 | 1991-04-19 | Pf Medicament | |
| EP0747348A4 (en) * | 1994-02-22 | 1999-07-07 | Asahi Chemical Ind | AMINOALKYLCYCLOPROPAN DERIVATIVES |
| FR2752732B1 (fr) * | 1996-08-28 | 1998-11-20 | Pf Medicament | Forme galenique a liberation prolongee de milnacipran |
| JP4418717B2 (ja) * | 2004-06-24 | 2010-02-24 | 住友化学株式会社 | （ｚ）−１−フェニル−１−ジエチルアミノカルボニル−２−アミノメチルシクロプロパン塩酸塩の製造方法 |
| JP4828863B2 (ja) * | 2005-01-28 | 2011-11-30 | 住友化学株式会社 | （ｚ）−１−フェニル−１−（ｎ，ｎ−ジエチルアミノカルボニル）−２−フタルイミドメチルシクロプロパンの製造方法 |
| CA2611724C (en) | 2005-06-10 | 2014-07-29 | Pierre Fabre Medicament S.A. | Stabilized milnacipran formulation |
| KR100772244B1 (ko) * | 2005-07-20 | 2007-11-01 | 안국약품 주식회사 | 밀나시프란염산염의 제조방법 |
| JP5338035B2 (ja) * | 2006-04-17 | 2013-11-13 | 住友化学株式会社 | 多環式ラクタム類の製造方法 |
| EP2014647A4 (en) * | 2006-04-17 | 2010-09-08 | Sumitomo Chemical Co | METHOD FOR THE PRODUCTION OF POLYCYCLIC LACTAM |
| WO2008104957A2 (en) * | 2007-02-28 | 2008-09-04 | Ranbaxy Laboratories Limited | Novel polymorphic forms of milnacipran hydrochloride |
| FR2941454B1 (fr) | 2009-01-29 | 2011-04-01 | Pf Medicament | Proced de synthese du (1s,2r)-milnacipran |
| US20100274050A1 (en) * | 2009-04-23 | 2010-10-28 | Glenmark Generics Limited | Solid milnacipran and process for the preparation of the same |
| EP2699539B1 (en) | 2011-04-21 | 2019-03-06 | Emory University | Cyclopropyl derivatives and methods of use |
| CN103242289B (zh) * | 2012-02-03 | 2015-01-07 | 暨明医药科技（苏州）有限公司 | N,n-二烯丙基-(1r, 2r)-2-胺甲基-1-(2-噻吩)环丙烷酰胺盐酸盐的制备方法 |
| WO2014009767A1 (en) | 2012-07-07 | 2014-01-16 | Micro Labs Limited | An improved process for the preparation of 1-aryl 2-aminomethyl cyclopropane carboxyamide (z) derivatives, their isomers and salts |
| JP2015534464A (ja) | 2012-10-09 | 2015-12-03 | カリフォルニア インスティチュート オブ テクノロジー | ヘム酵素によって触媒されるインビボおよびインビトロオレフィンシクロプロパン化 |
| FR2998892B1 (fr) * | 2012-12-04 | 2015-01-02 | Pf Medicament | Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments |
| CN103613513B (zh) * | 2013-12-09 | 2016-01-20 | 上海现代制药股份有限公司 | 盐酸米那普仑中间体及其制备方法和应用 |
| US9399762B2 (en) | 2014-02-18 | 2016-07-26 | California Institute Of Technology | Methods and systems for sulfimidation or sulfoximidation of organic molecules |
| CN104058992A (zh) * | 2014-06-13 | 2014-09-24 | 上海现代制药股份有限公司 | 左旋米那普仑盐酸盐的晶型 |
| US10131624B2 (en) | 2014-11-04 | 2018-11-20 | Quimica Sintetica, S.A. | Process for the preparation of (1S,2R)-Milnacipran |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2508035A1 (fr) * | 1981-06-23 | 1982-12-24 | Fabre Sa Pierre | Derives d'aryl-1-aminomethyl-2 cyclopropanes carboxamides (z), leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central |
-
1985
- 1985-04-25 FR FR8506335A patent/FR2581059B1/fr not_active Expired
-
1986
- 1986-04-14 GR GR860980A patent/GR860980B/el unknown
- 1986-04-17 AU AU56343/86A patent/AU587613B2/en not_active Expired
- 1986-04-18 ZA ZA862929A patent/ZA862929B/xx unknown
- 1986-04-21 IE IE105786A patent/IE59015B1/en not_active IP Right Cessation
- 1986-04-22 EP EP86400873A patent/EP0200638B1/fr not_active Expired
- 1986-04-22 DE DE8686400873T patent/DE3662877D1/de not_active Expired
- 1986-04-22 AT AT86400873T patent/ATE42273T1/de not_active IP Right Cessation
- 1986-04-22 NO NO861573A patent/NO165143C/no unknown
- 1986-04-22 YU YU655/86A patent/YU44915B/xx unknown
- 1986-04-23 KR KR1019860003133A patent/KR940006764B1/ko not_active IP Right Cessation
- 1986-04-23 CA CA000507320A patent/CA1266486A/fr not_active Expired - Lifetime
- 1986-04-24 SU SU864027356A patent/SU1443797A3/ru active
- 1986-04-24 PT PT82461A patent/PT82461B/pt unknown
- 1986-04-24 HU HU861711A patent/HU195182B/hu unknown
- 1986-04-24 JP JP61095850A patent/JPS61251650A/ja active Granted
- 1986-04-24 DK DK191286A patent/DK170888B1/da not_active IP Right Cessation
- 1986-04-24 ES ES554321A patent/ES8704449A1/es not_active Expired
- 1986-04-24 MX MX2307A patent/MX162896B/es unknown
- 1986-04-25 AR AR30375986A patent/AR240695A1/es active
- 1986-04-25 OA OA58846A patent/OA08241A/xx unknown
- 1986-04-25 FI FI861755A patent/FI87196C/fi not_active IP Right Cessation
-
1993
- 1993-03-04 GE GEAP1993566A patent/GEP19970789B/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |