OA08241A - Process for the preparation of 1-phenyl-diethylamino carbonyl-1-aminomethyl-cyclopropane hydrochloride (Z). - Google Patents

Process for the preparation of 1-phenyl-diethylamino carbonyl-1-aminomethyl-cyclopropane hydrochloride (Z).

Info

Publication number
OA08241A
OA08241A OA58846A OA58846A OA08241A OA 08241 A OA08241 A OA 08241A OA 58846 A OA58846 A OA 58846A OA 58846 A OA58846 A OA 58846A OA 08241 A OA08241 A OA 08241A
Authority
OA
OAPI
Prior art keywords
aminomethyl
phenyl
preparation
diethylamino carbonyl
cyclopropane hydrochloride
Prior art date
Application number
OA58846A
Other languages
French (fr)
Inventor
Bernard Bonnaud
Henri Cousse
Gilbert Mouzin
Jean-Francois Patoiseau
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9318686&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA08241(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of OA08241A publication Critical patent/OA08241A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
OA58846A 1985-04-25 1986-04-25 Process for the preparation of 1-phenyl-diethylamino carbonyl-1-aminomethyl-cyclopropane hydrochloride (Z). OA08241A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8506335A FR2581059B1 (en) 1985-04-25 1985-04-25 PROCESS FOR THE PREPARATION OF PHENYL-1 HYDROCHLORIDE DIETHYL AMINO CARBONYL-1 AMINOMETHYL-2 CYCLOPROPANE (Z)

Publications (1)

Publication Number Publication Date
OA08241A true OA08241A (en) 1987-10-30

Family

ID=9318686

Family Applications (1)

Application Number Title Priority Date Filing Date
OA58846A OA08241A (en) 1985-04-25 1986-04-25 Process for the preparation of 1-phenyl-diethylamino carbonyl-1-aminomethyl-cyclopropane hydrochloride (Z).

Country Status (23)

Country Link
EP (1) EP0200638B1 (en)
JP (1) JPS61251650A (en)
KR (1) KR940006764B1 (en)
AR (1) AR240695A1 (en)
AT (1) ATE42273T1 (en)
AU (1) AU587613B2 (en)
CA (1) CA1266486A (en)
DE (1) DE3662877D1 (en)
DK (1) DK170888B1 (en)
ES (1) ES8704449A1 (en)
FI (1) FI87196C (en)
FR (1) FR2581059B1 (en)
GE (1) GEP19970789B (en)
GR (1) GR860980B (en)
HU (1) HU195182B (en)
IE (1) IE59015B1 (en)
MX (1) MX162896B (en)
NO (1) NO165143C (en)
OA (1) OA08241A (en)
PT (1) PT82461B (en)
SU (1) SU1443797A3 (en)
YU (1) YU44915B (en)
ZA (1) ZA862929B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2640972B1 (en) * 1988-12-28 1991-04-19 Pf Medicament
EP0747348A4 (en) * 1994-02-22 1999-07-07 Asahi Chemical Ind Aminoalkylcyclopropane derivative
FR2752732B1 (en) * 1996-08-28 1998-11-20 Pf Medicament EXTENDED RELEASE GALENIC FORM OF MILNACIPRAN
JP4418717B2 (en) * 2004-06-24 2010-02-24 住友化学株式会社 Process for producing (Z) -1-phenyl-1-diethylaminocarbonyl-2-aminomethylcyclopropane hydrochloride
JP4828863B2 (en) * 2005-01-28 2011-11-30 住友化学株式会社 Process for producing (Z) -1-phenyl-1- (N, N-diethylaminocarbonyl) -2-phthalimidomethylcyclopropane
WO2006132307A1 (en) 2005-06-10 2006-12-14 Pierre Fabre Medicament S.A. Stabilized milnacipran formulation
KR100772244B1 (en) * 2005-07-20 2007-11-01 안국약품 주식회사 Method for the preparation of milnacipran hydrogen chloride salt
EP2014647A4 (en) * 2006-04-17 2010-09-08 Sumitomo Chemical Co Process for producing polycyclic lactam
JP5338035B2 (en) * 2006-04-17 2013-11-13 住友化学株式会社 Process for producing polycyclic lactams
EP2114868A2 (en) * 2007-02-28 2009-11-11 Ranbaxy Laboratories Limited Novel polymorphic forms of milnacipran hydrochloride
FR2941454B1 (en) 2009-01-29 2011-04-01 Pf Medicament PROCESS FOR THE SYNTHESIS OF (1S, 2R) -MILNACIPRAN
US20100274050A1 (en) * 2009-04-23 2010-10-28 Glenmark Generics Limited Solid milnacipran and process for the preparation of the same
US20140045936A1 (en) * 2011-04-21 2014-02-13 Wake Forest University Health Sciences Cyclopropyl derivatives and methods of use
CN103242289B (en) * 2012-02-03 2015-01-07 暨明医药科技（苏州）有限公司 Preparation method of N,N-diallyl-(1R,2R)-2-aminomethyl-1-(2-thienyl)cyclopropanecarboxamide hydrochloride
WO2014009767A1 (en) 2012-07-07 2014-01-16 Micro Labs Limited An improved process for the preparation of 1-aryl 2-aminomethyl cyclopropane carboxyamide (z) derivatives, their isomers and salts
JP2015534464A (en) 2012-10-09 2015-12-03 カリフォルニア インスティチュート オブ テクノロジー In vivo and in vitro olefin cyclopropanation catalyzed by heme enzymes
FR2998892B1 (en) * 2012-12-04 2015-01-02 Pf Medicament AMINOCYCLOBUTANE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USE AS MEDICAMENTS
CN103613513B (en) * 2013-12-09 2016-01-20 上海现代制药股份有限公司 Milnacipran hydrochloride intermediate and its preparation method and application
US9399762B2 (en) 2014-02-18 2016-07-26 California Institute Of Technology Methods and systems for sulfimidation or sulfoximidation of organic molecules
CN104058992A (en) * 2014-06-13 2014-09-24 上海现代制药股份有限公司 Crystal form of levomilnacipran hydrochloride
WO2016071303A1 (en) 2014-11-04 2016-05-12 Quimica Sintetica, S.A. Process for the preparation of (1s,2r)-milnacipran

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2508035A1 (en) * 1981-06-23 1982-12-24 Fabre Sa Pierre ARYL-1-AMINOMETHYL-2 CYCLOPROPANES CARBOXAMIDE (Z) DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS

Also Published As

Publication number Publication date
FR2581059A1 (en) 1986-10-31
GR860980B (en) 1986-08-25
EP0200638A1 (en) 1986-11-05
MX162896B (en) 1991-07-08
ES554321A0 (en) 1987-04-01
FR2581059B1 (en) 1988-04-22
JPH0567136B2 (en) 1993-09-24
DK191286D0 (en) 1986-04-24
EP0200638B1 (en) 1989-04-19
KR940006764B1 (en) 1994-07-27
FI87196B (en) 1992-08-31
KR860008126A (en) 1986-11-12
DK170888B1 (en) 1996-03-04
FI861755A0 (en) 1986-04-25
NO165143C (en) 1991-01-09
AR240695A1 (en) 1990-09-28
NO861573L (en) 1986-10-27
ATE42273T1 (en) 1989-05-15
HUT40618A (en) 1987-01-28
ES8704449A1 (en) 1987-04-01
HU195182B (en) 1988-04-28
IE861057L (en) 1986-10-25
SU1443797A3 (en) 1988-12-07
FI861755A (en) 1986-10-26
IE59015B1 (en) 1993-12-15
FI87196C (en) 1992-12-10
PT82461B (en) 1988-10-14
PT82461A (en) 1986-05-01
YU65586A (en) 1987-12-31
YU44915B (en) 1991-04-30
CA1266486A (en) 1990-03-06
JPS61251650A (en) 1986-11-08
AU5634386A (en) 1986-10-30
NO165143B (en) 1990-09-24
DK191286A (en) 1986-10-26
AU587613B2 (en) 1989-08-24
DE3662877D1 (en) 1989-05-24
GEP19970789B (en) 1997-01-28
ZA862929B (en) 1986-12-30

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