NZ709124A - Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same - Google Patents

Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same

Info

Publication number
NZ709124A
NZ709124A NZ709124A NZ70912410A NZ709124A NZ 709124 A NZ709124 A NZ 709124A NZ 709124 A NZ709124 A NZ 709124A NZ 70912410 A NZ70912410 A NZ 70912410A NZ 709124 A NZ709124 A NZ 709124A
Authority
NZ
New Zealand
Prior art keywords
cell
biliary tree
methods
stem cells
multipotent stem
Prior art date
Application number
NZ709124A
Other languages
English (en)
Inventor
Cai-Bin Cui
Domenico Alvaro
Vincenzo Cardinale
Eugenio Gaudio
Yunfang Wang
Lola M Reid
Guido Carpino
Original Assignee
Univ North Carolina Chapel Hill
Sapienza Univ Di Roma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43922533&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ709124(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ North Carolina Chapel Hill, Sapienza Univ Di Roma filed Critical Univ North Carolina Chapel Hill
Priority to NZ724435A priority Critical patent/NZ724435B2/en
Publication of NZ709124A publication Critical patent/NZ709124A/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/413—Gall bladder; Bile
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C12N5/068—Stem cells; Progenitors
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    • C12N2500/00—Specific components of cell culture medium
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    • C12N2500/05—Inorganic components
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/38—Hormones with nuclear receptors
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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NZ709124A 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same NZ709124A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ724435A NZ724435B2 (en) 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25684609P 2009-10-30 2009-10-30
NZ622427A NZ622427A (en) 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same

Publications (1)

Publication Number Publication Date
NZ709124A true NZ709124A (en) 2017-06-30

Family

ID=43922533

Family Applications (3)

Application Number Title Priority Date Filing Date
NZ709124A NZ709124A (en) 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same
NZ622427A NZ622427A (en) 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same
NZ600068A NZ600068A (en) 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic billary tree and methods of isolating same

Family Applications After (2)

Application Number Title Priority Date Filing Date
NZ622427A NZ622427A (en) 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same
NZ600068A NZ600068A (en) 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic billary tree and methods of isolating same

Country Status (20)

Country Link
US (1) US20110135610A1 (enExample)
EP (2) EP3725874A1 (enExample)
JP (2) JP5936547B2 (enExample)
KR (4) KR20200146043A (enExample)
CN (2) CN102918145B (enExample)
AR (2) AR078849A1 (enExample)
AU (1) AU2016210783B2 (enExample)
BR (1) BR112012009848B1 (enExample)
CA (2) CA2779144C (enExample)
CL (1) CL2012001117A1 (enExample)
CR (1) CR20120254A (enExample)
ES (1) ES2819028T3 (enExample)
IL (2) IL219454A (enExample)
MX (1) MX2012005087A (enExample)
NZ (3) NZ709124A (enExample)
PH (1) PH12012500845A1 (enExample)
RU (2) RU2756584C2 (enExample)
SG (2) SG10201913006XA (enExample)
TW (3) TWI641688B (enExample)
WO (1) WO2011053690A1 (enExample)

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WO2012178215A1 (en) 2011-06-23 2012-12-27 The Children's Hospital Of Philadelphia Self-renewing endodermal progenitor lines generated from human pluripotent stem cells and methods of use thereof
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CN103266084B (zh) * 2013-05-27 2015-03-04 刘卫辉 富集干细胞的三步分离法
CN106461676B (zh) * 2014-03-17 2019-07-05 新加坡科技研究局 基于核因子κB易位预测化合物的毒性的方法
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GB201510950D0 (en) * 2015-06-22 2015-08-05 Cambridge Entpr Ltd In vitro Production of Cholangiocytes
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GB201521179D0 (en) 2015-12-01 2016-01-13 Univ Leuven Kath Methods for differentiating cells into hepatic stellate cells
CN105807053B (zh) * 2016-04-15 2019-04-02 苏州药明康德新药开发股份有限公司 一种肿瘤解离试剂在流式细胞检测中的应用
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
KR20190141168A (ko) * 2017-04-06 2019-12-23 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 동결보존 방법
CA3112650A1 (en) * 2018-03-29 2019-10-03 The University Of North Carolina At Chapel Hill Stem/progenitor cells from duodenal brunner's glands and methods of isolating and using them
CN112126618B (zh) * 2019-06-24 2023-09-12 上海拜羡生物科技有限公司 一种人胆囊干细胞的获取和长期体外培养的方法
CN113388569B (zh) * 2020-08-28 2022-05-17 广东乾晖生物科技有限公司 肝脏类器官的制备方法
BR112023025612A2 (pt) * 2021-06-30 2024-02-27 Polbionica Sp Z O O Meio para armazenar ilhotas pancreáticas isoladas, e, método de armazenamento de ilhotas pancreáticas isoladas
CN116478904A (zh) * 2022-01-17 2023-07-25 香港中文大学 肝样细胞和人工肝组织的制备方法以及应用
CN115975913B (zh) * 2023-02-03 2024-06-04 北京中医药大学深圳医院(龙岗) 一种利用多能干细胞诱导分化胆囊祖细胞的方法

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