AU2016210783B2 - Multipotent stem cells from the extrahepatic billary tree and methods of isolating same - Google Patents

Multipotent stem cells from the extrahepatic billary tree and methods of isolating same Download PDF

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Publication number
AU2016210783B2
AU2016210783B2 AU2016210783A AU2016210783A AU2016210783B2 AU 2016210783 B2 AU2016210783 B2 AU 2016210783B2 AU 2016210783 A AU2016210783 A AU 2016210783A AU 2016210783 A AU2016210783 A AU 2016210783A AU 2016210783 B2 AU2016210783 B2 AU 2016210783B2
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cells
cell
stem
aug
biliary tree
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AU2016210783A1 (en
Inventor
Domenico Alvaro
Vincenzo Cardinale
Guido Carpino
Cai-Bin Cui
Eugenio Gaudio
Lola M. Reid
Yunfang Wang
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Sapienza University of Rome
University of North Carolina at Chapel Hill
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Sapienza University of Rome
University of North Carolina at Chapel Hill
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Priority claimed from AU2010313386A external-priority patent/AU2010313386B2/en
Application filed by Sapienza University of Rome, University of North Carolina at Chapel Hill filed Critical Sapienza University of Rome
Priority to AU2016210783A priority Critical patent/AU2016210783B2/en
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/413—Gall bladder; Bile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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AU2016210783A 2009-10-30 2016-08-08 Multipotent stem cells from the extrahepatic billary tree and methods of isolating same Ceased AU2016210783B2 (en)

Priority Applications (1)

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AU2016210783A AU2016210783B2 (en) 2009-10-30 2016-08-08 Multipotent stem cells from the extrahepatic billary tree and methods of isolating same

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US25684609P 2009-10-30 2009-10-30
US61/256,846 2009-10-30
PCT/US2010/054450 WO2011053690A1 (en) 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic billary tree and methods of isolating same
AU2010313386A AU2010313386B2 (en) 2009-10-30 2010-10-28 Multipotent stem cells from the extrahepatic billary tree and methods of isolating same
AU2016210783A AU2016210783B2 (en) 2009-10-30 2016-08-08 Multipotent stem cells from the extrahepatic billary tree and methods of isolating same

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AU2016210783A1 AU2016210783A1 (en) 2016-09-01
AU2016210783B2 true AU2016210783B2 (en) 2018-06-28

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US (1) US20110135610A1 (enExample)
EP (2) EP3725874A1 (enExample)
JP (2) JP5936547B2 (enExample)
KR (4) KR20200146043A (enExample)
CN (2) CN102918145B (enExample)
AR (2) AR078849A1 (enExample)
AU (1) AU2016210783B2 (enExample)
BR (1) BR112012009848B1 (enExample)
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CL (1) CL2012001117A1 (enExample)
CR (1) CR20120254A (enExample)
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IL (2) IL219454A (enExample)
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SG (2) SG10201913006XA (enExample)
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ES2819028T3 (es) * 2009-10-30 2021-04-14 Univ North Carolina Chapel Hill Células madre multipotentes del árbol biliar extrahepático y métodos para su aislamiento
WO2012178215A1 (en) 2011-06-23 2012-12-27 The Children's Hospital Of Philadelphia Self-renewing endodermal progenitor lines generated from human pluripotent stem cells and methods of use thereof
US9533013B2 (en) 2013-03-13 2017-01-03 University Of North Carolina At Chapel Hill Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree
CN103266084B (zh) * 2013-05-27 2015-03-04 刘卫辉 富集干细胞的三步分离法
CN106461676B (zh) * 2014-03-17 2019-07-05 新加坡科技研究局 基于核因子κB易位预测化合物的毒性的方法
GB201507894D0 (en) * 2015-05-08 2015-06-24 Imagen Biotech Ltd Personalised media
GB201510950D0 (en) * 2015-06-22 2015-08-05 Cambridge Entpr Ltd In vitro Production of Cholangiocytes
US10683486B2 (en) * 2015-10-30 2020-06-16 Biolamina Ab Methods for producing hepatocytes
GB201521179D0 (en) 2015-12-01 2016-01-13 Univ Leuven Kath Methods for differentiating cells into hepatic stellate cells
CN105807053B (zh) * 2016-04-15 2019-04-02 苏州药明康德新药开发股份有限公司 一种肿瘤解离试剂在流式细胞检测中的应用
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
KR20190141168A (ko) * 2017-04-06 2019-12-23 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 동결보존 방법
CA3112650A1 (en) * 2018-03-29 2019-10-03 The University Of North Carolina At Chapel Hill Stem/progenitor cells from duodenal brunner's glands and methods of isolating and using them
CN112126618B (zh) * 2019-06-24 2023-09-12 上海拜羡生物科技有限公司 一种人胆囊干细胞的获取和长期体外培养的方法
CN113388569B (zh) * 2020-08-28 2022-05-17 广东乾晖生物科技有限公司 肝脏类器官的制备方法
BR112023025612A2 (pt) * 2021-06-30 2024-02-27 Polbionica Sp Z O O Meio para armazenar ilhotas pancreáticas isoladas, e, método de armazenamento de ilhotas pancreáticas isoladas
CN116478904A (zh) * 2022-01-17 2023-07-25 香港中文大学 肝样细胞和人工肝组织的制备方法以及应用
CN115975913B (zh) * 2023-02-03 2024-06-04 北京中医药大学深圳医院(龙岗) 一种利用多能干细胞诱导分化胆囊祖细胞的方法

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