NZ593227A - Gene expression markers (MYBL2) for colorectal cancer prognosis - Google Patents
Gene expression markers (MYBL2) for colorectal cancer prognosisInfo
- Publication number
- NZ593227A NZ593227A NZ593227A NZ59322707A NZ593227A NZ 593227 A NZ593227 A NZ 593227A NZ 593227 A NZ593227 A NZ 593227A NZ 59322707 A NZ59322707 A NZ 59322707A NZ 593227 A NZ593227 A NZ 593227A
- Authority
- NZ
- New Zealand
- Prior art keywords
- colorectal cancer
- mybl2
- gene expression
- human subject
- clinical outcome
- Prior art date
Links
- 206010009944 Colon cancer Diseases 0.000 title abstract 4
- 208000001333 Colorectal Neoplasms Diseases 0.000 title abstract 4
- 230000014509 gene expression Effects 0.000 title abstract 4
- 101000593405 Homo sapiens Myb-related protein B Proteins 0.000 title abstract 3
- 102100034670 Myb-related protein B Human genes 0.000 title abstract 3
- 238000004393 prognosis Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000002596 correlated effect Effects 0.000 abstract 1
- 238000002271 resection Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57446—Specifically defined cancers of stomach or intestine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75839206P | 2006-01-11 | 2006-01-11 | |
| US80027706P | 2006-05-12 | 2006-05-12 | |
| US81007706P | 2006-05-31 | 2006-05-31 | |
| NZ569788A NZ569788A (en) | 2006-01-11 | 2007-01-11 | RNA transcript of BGN as a gene expression markers for colorectal cancer prognosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ593227A true NZ593227A (en) | 2012-10-26 |
Family
ID=38257063
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ593227A NZ593227A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (MYBL2) for colorectal cancer prognosis |
| NZ569788A NZ569788A (en) | 2006-01-11 | 2007-01-11 | RNA transcript of BGN as a gene expression markers for colorectal cancer prognosis |
| NZ593229A NZ593229A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (gadd45b) for colorectal cancer prognosis |
| NZ593228A NZ593228A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (inhba) for colorectal cancer prognosis |
| NZ593225A NZ593225A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (CMYC and Ki-67) for colorectal cancer prognosis |
| NZ593224A NZ593224A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (fap) for colorectal cancer prognosis |
| NZ593226A NZ593226A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (efnb2) for colorectal cancer prognosis |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ569788A NZ569788A (en) | 2006-01-11 | 2007-01-11 | RNA transcript of BGN as a gene expression markers for colorectal cancer prognosis |
| NZ593229A NZ593229A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (gadd45b) for colorectal cancer prognosis |
| NZ593228A NZ593228A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (inhba) for colorectal cancer prognosis |
| NZ593225A NZ593225A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (CMYC and Ki-67) for colorectal cancer prognosis |
| NZ593224A NZ593224A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (fap) for colorectal cancer prognosis |
| NZ593226A NZ593226A (en) | 2006-01-11 | 2007-01-11 | Gene expression markers (efnb2) for colorectal cancer prognosis |
Country Status (14)
| Country | Link |
|---|---|
| US (10) | US7695913B2 (enExample) |
| EP (9) | EP2412823B1 (enExample) |
| JP (7) | JP5297202B2 (enExample) |
| KR (1) | KR20090003178A (enExample) |
| AU (1) | AU2007204826B2 (enExample) |
| BR (1) | BRPI0706511A2 (enExample) |
| CA (1) | CA2636984A1 (enExample) |
| DK (1) | DK1974058T3 (enExample) |
| ES (1) | ES2491222T3 (enExample) |
| IL (1) | IL192794A (enExample) |
| MX (1) | MX2008008973A (enExample) |
| NO (1) | NO20083461L (enExample) |
| NZ (7) | NZ593227A (enExample) |
| WO (1) | WO2007082099A2 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4606879B2 (ja) | 2002-11-15 | 2011-01-05 | ジェノミック ヘルス, インコーポレイテッド | Egfr陽性癌の遺伝子発現プロファイリング |
| EP1737980A2 (en) | 2004-04-09 | 2007-01-03 | Fondazione IRCCS Istituto Nazionale dei Tumori | Gene expression markers for predicting response to chemotherapy |
| DK1974058T3 (da) * | 2006-01-11 | 2014-09-01 | Genomic Health Inc | Genekspressionsmarkører til prognosticering af kolorektal cancer |
| AU2007253740A1 (en) | 2006-05-18 | 2007-11-29 | Molecular Profiling Institute, Inc. | System and method for determining individualized medical intervention for a disease state |
| US8768629B2 (en) | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| US20090076734A1 (en) | 2007-03-22 | 2009-03-19 | Torres-Roca Javier F | Gene Signature for the Prediction of Radiation Therapy Response |
| US20080234946A1 (en) * | 2007-03-22 | 2008-09-25 | University Of South Florida | Predictive radiosensitivity network model |
| AU2008231575A1 (en) | 2007-03-27 | 2008-10-02 | Immunovia Ab | Protein signature/markers for the detection of adenocarcinoma |
| US20090123920A1 (en) * | 2007-11-08 | 2009-05-14 | Maher Albitar | Jak2 mutations |
| ES2332167B1 (es) * | 2007-12-04 | 2010-10-25 | Universidad Autonoma De Madrid | Empleo de trefoil factor-family 3 (tff3) en el pronostico de sujetos diagnosticados con cancer colorectal. |
| WO2009123634A1 (en) * | 2008-04-02 | 2009-10-08 | Regents Of The University Of California | Systems and methods for predicting response of biological samples |
| US8067178B2 (en) | 2008-03-14 | 2011-11-29 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| AU2009246398A1 (en) | 2008-05-14 | 2009-11-19 | Bristol-Myers Squibb Company | Predictors of patient response to treatment with EGF receptor inhibitors |
| US20100029748A1 (en) * | 2008-08-04 | 2010-02-04 | Sloan-Kettering Institute For Cancer Research | Metastasis Promoting Genes and Proteins |
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20100221752A2 (en) * | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| WO2010042228A2 (en) * | 2008-10-10 | 2010-04-15 | Cornell University | Methods for predicting disease outcome in patients with colon cancer |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| US8765383B2 (en) | 2009-04-07 | 2014-07-01 | Genomic Health, Inc. | Methods of predicting cancer risk using gene expression in premalignant tissue |
| MX2011011571A (es) * | 2009-05-01 | 2012-02-13 | Genomic Health Inc | Algoritmo de perfil de expresion genica y prueba para probabilidad de recidiva de cancer colorrectal y respuesta a la quimioterapia. |
| TWI513465B (zh) * | 2009-06-25 | 2015-12-21 | Regeneron Pharma | 以dll4拮抗劑與化學治療劑治療癌症之方法 |
| CA2804391A1 (en) | 2010-07-07 | 2012-01-12 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US20130116150A1 (en) | 2010-07-09 | 2013-05-09 | Somalogic, Inc. | Lung Cancer Biomarkers and Uses Thereof |
| IL243203A (en) | 2010-07-27 | 2017-04-30 | Genomic Health Inc | Method for using gene expression to determine prognosis of prostate cancer |
| KR101857462B1 (ko) | 2010-08-13 | 2018-05-14 | 소마로직, 인크. | 췌장암 바이오마커 및 그것의 용도 |
| WO2012030840A2 (en) | 2010-08-30 | 2012-03-08 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| KR20130115250A (ko) | 2010-09-15 | 2013-10-21 | 알막 다이아그노스틱스 리미티드 | 암에 대한 분자적 진단 테스트 |
| CA2825218A1 (en) * | 2011-01-25 | 2012-08-02 | Almac Diagnostics Limited | Colon cancer gene expression signatures and methods of use |
| AU2012330817A1 (en) * | 2011-11-04 | 2014-05-22 | Oslo Universitetssykehus Hf | Methods and biomarkers for analysis of colorectal cancer |
| MX2014006404A (es) | 2011-11-28 | 2015-03-03 | Institució Catalana De Recerca I Estudis Avançats | Metodos y kits para el pronostico del cancer colorrectal. |
| US10519506B2 (en) | 2011-12-22 | 2019-12-31 | Baylor Research Institute | Identification of metastasis-specific miRNA and hypomethylation signatures in human colorectal cancer |
| WO2013104990A1 (en) * | 2012-01-09 | 2013-07-18 | Oslo Universitetssykehus Hf | Methods and biomarkers for analysis of colorectal cancer |
| HK1201881A1 (en) | 2012-01-31 | 2015-09-11 | Genomic Health, Inc. | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| WO2013150167A2 (es) | 2012-04-03 | 2013-10-10 | Servicio Andaluz De Salud | Modelo de expresión de microarn como indicador de supervivencia en pacientes de cancer colorrectal metastásico |
| US20160222457A1 (en) * | 2012-11-14 | 2016-08-04 | Mayo Foundation For Medical Education And Research | Methods and materials for identifying malignant skin lesions |
| ES2938766T3 (es) | 2012-11-16 | 2023-04-14 | Myriad Genetics Inc | Firmas génicas para el pronóstico de cáncer |
| ES2475366B1 (es) * | 2012-12-10 | 2015-05-05 | Fundación Imdea Alimentación | Métodos y kits para el pronóstico del cáncer colorrectal |
| US9994908B2 (en) | 2013-03-14 | 2018-06-12 | Abbott Molecular Inc. | Materials and methods for assessment of colorectal adenoma |
| AR096507A1 (es) * | 2013-05-30 | 2016-01-13 | Fundació Institució Catalana De Recerca I Estudis Avançats | Métodos y kits para el pronóstico del cáncer colorrectal |
| US10185809B1 (en) * | 2013-10-15 | 2019-01-22 | Iqvia Inc. | Patient projection methodology |
| GB201319878D0 (en) * | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
| CA2943827A1 (en) * | 2014-03-28 | 2015-10-01 | Applied Proteomics, Inc. | Protein biomarker profiles for detecting colorectal tumors |
| CA2947624A1 (en) | 2014-05-13 | 2015-11-19 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US20170275700A1 (en) | 2014-08-14 | 2017-09-28 | Mayo Foundation For Medical Education And Research | Methods and materials for identifying metastatic malignant skin lesions and treating skin cancer |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| EP3210143B1 (en) | 2014-10-24 | 2020-12-09 | Koninklijke Philips N.V. | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities |
| CA2965442C (en) | 2014-10-24 | 2024-06-25 | Koninklijke Philips N.V. | Assessment of tgf-b cellular signaling pathway activity using mathematical modelling of target gene expression |
| ES2838923T3 (es) | 2014-10-24 | 2021-07-02 | Koninklijke Philips Nv | Pronóstico médico y predicción de la respuesta a tratamiento usando múltiples actividades de la ruta de señalización celular |
| DE112014007209T5 (de) | 2014-11-25 | 2017-08-03 | Mitsubishi Electric Corporation | Pneumatischer Antrieb |
| WO2016089928A1 (en) * | 2014-12-01 | 2016-06-09 | Weitz Andrew C | Methods for treating and assessing tumor invasion and metastasis |
| EP3274440A4 (en) | 2015-03-27 | 2019-03-06 | Exact Sciences Corporation | Detecting esophageal disorders |
| EP3073268A1 (en) * | 2015-03-27 | 2016-09-28 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Biomarker panel for diagnosing cancer |
| CA2982169A1 (en) | 2015-04-10 | 2016-10-13 | Applied Proteomics, Inc. | Protein biomarker panels for detecting colorectal cancer and advanced adenoma |
| WO2016208776A1 (ja) * | 2015-06-25 | 2016-12-29 | 株式会社国際電気通信基礎技術研究所 | 多器官連関システムを基盤とした予測装置、及び予測プログラム |
| BR112018002848A2 (pt) | 2015-08-14 | 2018-11-06 | Koninklijke Philips Nv | método, aparelho, mídia de armazenamento não transitório, programa de computador, kit para medir níveis de expressão de seis ou mais genes-alvo da via de sinalização celular |
| CN114594268A (zh) | 2016-03-29 | 2022-06-07 | 无限生物制药公司 | 用以预防或治疗肾脏疾病的活性组分的候选物质的筛选装置和筛选方法 |
| CN109414504B (zh) | 2016-03-29 | 2022-04-08 | 无限生物制药公司 | 药物组合物或食品组合物及评价活性成分体内效果的方法 |
| CN109477147A (zh) | 2016-05-10 | 2019-03-15 | 梅约医学教育与研究基金会 | 用于皮肤癌分期和治疗的方法和材料 |
| US11746381B2 (en) | 2017-03-10 | 2023-09-05 | Cancer Diagnostics Research Innvovations, LLC | Methods for diagnosing and treating gastric cancer using miRNA expression |
| WO2018224731A1 (en) * | 2017-06-05 | 2018-12-13 | Ls Cancerdiag Oy | A method for determining whether a subject is at risk to develop cancer and tools related thereto |
| EP3461916A1 (en) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of jak-stat3 cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3461915A1 (en) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3502279A1 (en) | 2017-12-20 | 2019-06-26 | Koninklijke Philips N.V. | Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression |
| JP7027179B2 (ja) * | 2018-01-24 | 2022-03-01 | キヤノン株式会社 | 給送回転体、シート給送装置及び画像形成装置 |
| US11549152B2 (en) | 2018-03-08 | 2023-01-10 | University Of Notre Dame Du Lac | Products for assessing colorectal cancer molecular subtype and risk of recurrence and for determining and administering treatment protocols based thereon |
| KR102007450B1 (ko) * | 2018-05-31 | 2019-08-05 | 한국과학기술연구원 | 대장암 치료제 발굴을 위한 신규 표적 치료 작용점의 스크리닝 방법 및 이를 이용하여 선별한 대장암 치료 예후 바이오마커 |
| AU2019310636B2 (en) | 2018-07-25 | 2025-06-26 | Mayo Foundation For Medical Education And Research | Gene signatures for predicting metastasis of melanoma and patient prognosis |
| US12370240B2 (en) | 2018-11-28 | 2025-07-29 | Genascence Corporation | Methods and compositions for treating osteoarthritis |
| WO2020123699A1 (en) * | 2018-12-11 | 2020-06-18 | The Trustees Of Columbia University In The City Of New York | Compounds and compositions that cause mycn and/or cmyc degradation and methods of use thereof |
| CN110257518B (zh) * | 2019-07-01 | 2022-08-02 | 复旦大学附属中山医院 | 一种用于预测转移性结直肠癌转化治疗疗效的基因集 |
| US12057959B2 (en) * | 2019-12-31 | 2024-08-06 | Mcafee, Llc | Device identification |
| KR102263984B1 (ko) * | 2020-02-21 | 2021-06-11 | 재단법인 아산사회복지재단 | 직장암 환자에서 수술-전 화학방사선치료의 반응을 예측하기 위한 분석방법 |
| KR102535150B1 (ko) * | 2020-04-14 | 2023-05-23 | 주식회사 베르티스 | 암의 예후 예측용 조성물 |
| AU2021263680A1 (en) * | 2020-04-29 | 2022-11-24 | Freenome Holdings, Inc. | RNA markers and methods for identifying colon cell proliferative disorders |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| CN112322730B (zh) * | 2020-10-16 | 2023-04-18 | 上海市第一人民医院 | 预测肿瘤耐药、复发的标志物kifc1及其抑制剂和应用 |
| EP4026918A1 (en) | 2021-01-12 | 2022-07-13 | Koninklijke Philips N.V. | Prediction of an outcome of a colorectal cancer subject |
| CN113667673B (zh) * | 2021-07-15 | 2024-02-06 | 武汉血液中心 | 一种类孟买血型FUT1 236delG等位基因及其检测方法和应用 |
| KR20230059642A (ko) * | 2021-10-26 | 2023-05-03 | 사회복지법인 삼성생명공익재단 | miRNA를 포함하는 대장암의 치료 및 전이 억제용 조성물 및 이의 용도 |
| CN116735874B (zh) * | 2022-03-11 | 2025-09-23 | 上海市免疫学研究所 | 结直肠癌肿瘤边界细胞亚群标志物组合及其应用 |
| WO2024035653A1 (en) * | 2022-08-06 | 2024-02-15 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Predictive biomarker in avastin in colon cancer |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020172987A1 (en) * | 1998-02-12 | 2002-11-21 | Terstappen Leon W.M.M. | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| EP1084273A1 (en) * | 1998-06-06 | 2001-03-21 | Genostic Pharma Limited | Probes used for genetic profiling |
| WO1999064627A2 (en) | 1998-06-06 | 1999-12-16 | Genostic Pharma Limited | Probes used for genetic profiling |
| WO2000024940A1 (en) | 1998-10-28 | 2000-05-04 | Vysis, Inc. | Cellular arrays and methods of detecting and using genetic disorder markers |
| EP0999016B1 (en) * | 1998-11-06 | 2001-07-11 | Temco S. R. L. | Cutter for cross cutting of webs |
| US6692916B2 (en) * | 1999-06-28 | 2004-02-17 | Source Precision Medicine, Inc. | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles |
| US6960439B2 (en) * | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| EP1265582A2 (en) * | 1999-09-29 | 2002-12-18 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| WO2001041815A2 (en) | 1999-12-10 | 2001-06-14 | Whitehead Institute For Biomedical Research | Metastasis genes and uses thereof |
| US7029677B2 (en) * | 2000-01-25 | 2006-04-18 | Nuvelo, Inc. | Methods of therapy and diagnosis using immunotargeting of CD84Hy1-expressing cells |
| US20050282157A1 (en) | 2000-04-06 | 2005-12-22 | Alexander Olek | Diagnosis of diseases associated with dna replication |
| WO2005000087A2 (en) | 2003-06-03 | 2005-01-06 | Chiron Corporation | Gene products differentially expressed in cancerous colon cells and their methods of use ii |
| US20020110832A1 (en) | 2000-08-03 | 2002-08-15 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| WO2002012328A2 (en) | 2000-08-03 | 2002-02-14 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| US20030166064A1 (en) * | 2000-08-03 | 2003-09-04 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| US20030077568A1 (en) * | 2000-09-15 | 2003-04-24 | Gish Kurt C. | Methods of diagnosis of colorectal cancer, compositions and methods of screening for colorectal cancer modulators |
| WO2002024956A2 (en) | 2000-09-19 | 2002-03-28 | Whitehead Institute For Biomedical Research | Genetic markers for tumors |
| AU2002246519A1 (en) * | 2000-11-20 | 2002-08-06 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| WO2002074156A2 (en) * | 2001-02-02 | 2002-09-26 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| AU2002311903A1 (en) * | 2001-05-09 | 2002-11-18 | University Hospitals Of Cleveland | Evaluation of ultraviolet radiation damage to skin using new genemarkers, methods and compositions related thereto |
| US20030148314A1 (en) | 2001-08-01 | 2003-08-07 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of colon cancer |
| US7622260B2 (en) * | 2001-09-05 | 2009-11-24 | The Brigham And Women's Hospital, Inc. | Diagnostic and prognostic tests |
| KR20040064275A (ko) * | 2001-11-09 | 2004-07-16 | 소스 프리시전 메디슨, 인코포레이티드 | 유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인 |
| WO2003041562A2 (en) * | 2001-11-14 | 2003-05-22 | Whitehead Institute For Biomedical Research | Molecular cancer diagnosis using tumor gene expression signature |
| WO2003050243A2 (en) | 2001-12-10 | 2003-06-19 | Millennium Pharmaceuticals Inc. | Novel genes encoding colon cancer antigens |
| US20070166704A1 (en) * | 2002-01-18 | 2007-07-19 | Fei Huang | Identification of polynucleotides and polypeptide for predicting activity of compounds that interact with protein tyrosine kinases and/or protein tyrosine kinase pathways |
| US7955800B2 (en) * | 2002-06-25 | 2011-06-07 | Advpharma Inc. | Metastasis-associated gene profiling for identification of tumor tissue, subtyping, and prediction of prognosis of patients |
| CA2498418A1 (en) * | 2002-09-10 | 2004-03-25 | Guennadi V. Glinskii | Gene segregation and biological sample classification methods |
| EP1560597A4 (en) | 2002-10-29 | 2007-06-27 | Pharmacia Corp | DIFFERENTIALLY EXPRESSED GENES INVOLVED IN CANCER, POLYPEPTIDES CODED THEREWITH, AND METHODS OF USING GENES |
| WO2004074518A1 (en) * | 2003-02-20 | 2004-09-02 | Genomic Health, Inc. | Use of intronic rna to measure gene expression |
| DK1644858T3 (da) | 2003-07-10 | 2018-01-22 | Genomic Health Inc | Funktionel beklædning med mindst et yderlag og en indermembran. |
| US20050014165A1 (en) * | 2003-07-18 | 2005-01-20 | California Pacific Medical Center | Biomarker panel for colorectal cancer |
| WO2005015236A2 (en) | 2003-07-18 | 2005-02-17 | Roche Diagnostics Gmbh | A method for predicting the progression of adenocarcinoma |
| JP2007507204A (ja) * | 2003-07-29 | 2007-03-29 | ブリストル−マイヤーズ スクイブ カンパニー | サイクリン依存性キナーゼモデュレーションのバイオマーカー |
| EP1522594A3 (en) | 2003-10-06 | 2005-06-22 | Bayer HealthCare AG | Methods and kits for investigating cancer |
| WO2005076005A2 (en) | 2004-01-30 | 2005-08-18 | Medizinische Universität Wien | A method for classifying a tumor cell sample based upon differential expression of at least two genes |
| US20060195266A1 (en) * | 2005-02-25 | 2006-08-31 | Yeatman Timothy J | Methods for predicting cancer outcome and gene signatures for use therein |
| CA2562835A1 (en) | 2004-04-16 | 2005-10-27 | Monash University | A method for monitoring the progress of cancer |
| US20080032293A1 (en) | 2004-07-15 | 2008-02-07 | The University Of North Carolina At Chapel Hill | Housekeeping Genes And Methods For Identifying Same |
| US20060183893A1 (en) | 2005-01-25 | 2006-08-17 | North Don A | Nucleic acids for apoptosis of cancer cells |
| EP1910557A2 (en) | 2005-04-07 | 2008-04-16 | Chiron Corporation | Cancer-related genes |
| WO2006138275A2 (en) * | 2005-06-13 | 2006-12-28 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| EP1954708A4 (en) | 2005-11-23 | 2009-05-13 | Univ Utah Res Found | Methods and compositions involving intrinsic genes |
| US20090215054A1 (en) | 2005-12-13 | 2009-08-27 | Carter Scott L | Prognosis indicators for solid human tumors |
| NZ544432A (en) | 2005-12-23 | 2009-07-31 | Pacific Edge Biotechnology Ltd | Prognosis prediction for colorectal cancer using a prognositc signature comprising markers ME2 and FAS |
| DK1974058T3 (da) | 2006-01-11 | 2014-09-01 | Genomic Health Inc | Genekspressionsmarkører til prognosticering af kolorektal cancer |
| US20100009905A1 (en) | 2006-03-24 | 2010-01-14 | Macina Roberto A | Compositions and Methods for Detection, Prognosis and Treatment of Colon Cancer |
| US20090258795A1 (en) * | 2007-03-15 | 2009-10-15 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| US8067178B2 (en) * | 2008-03-14 | 2011-11-29 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| US8765383B2 (en) * | 2009-04-07 | 2014-07-01 | Genomic Health, Inc. | Methods of predicting cancer risk using gene expression in premalignant tissue |
| MX2011011571A (es) * | 2009-05-01 | 2012-02-13 | Genomic Health Inc | Algoritmo de perfil de expresion genica y prueba para probabilidad de recidiva de cancer colorrectal y respuesta a la quimioterapia. |
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