NZ517681A - Amphiphilic prodrugs - Google Patents

Amphiphilic prodrugs

Info

Publication number
NZ517681A
NZ517681A NZ517681A NZ51768100A NZ517681A NZ 517681 A NZ517681 A NZ 517681A NZ 517681 A NZ517681 A NZ 517681A NZ 51768100 A NZ51768100 A NZ 51768100A NZ 517681 A NZ517681 A NZ 517681A
Authority
NZ
New Zealand
Prior art keywords
prodrug
etoposide
oligomer
therapeutic compound
formula
Prior art date
Application number
NZ517681A
Other languages
English (en)
Inventor
Nnochiri N Ekwuribe
Tatyana A Dyakonov
Christopher H Price
Original Assignee
Nobex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nobex Corp filed Critical Nobex Corp
Publication of NZ517681A publication Critical patent/NZ517681A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
NZ517681A 1999-09-13 2000-09-07 Amphiphilic prodrugs NZ517681A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15364999P 1999-09-13 1999-09-13
US09/474,915 US6713454B1 (en) 1999-09-13 1999-12-31 Prodrugs of etoposide and etoposide analogs
PCT/US2000/024520 WO2001019406A2 (en) 1999-09-13 2000-09-07 Amphiphilic prodrugs

Publications (1)

Publication Number Publication Date
NZ517681A true NZ517681A (en) 2004-01-30

Family

ID=26850733

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ517681A NZ517681A (en) 1999-09-13 2000-09-07 Amphiphilic prodrugs

Country Status (17)

Country Link
US (3) US6713454B1 (US07119074-20061010-C00036.png)
EP (1) EP1212099A2 (US07119074-20061010-C00036.png)
JP (1) JP2003509385A (US07119074-20061010-C00036.png)
KR (1) KR20020059398A (US07119074-20061010-C00036.png)
CN (1) CN1390143A (US07119074-20061010-C00036.png)
AU (1) AU7575600A (US07119074-20061010-C00036.png)
BR (1) BR0013948A (US07119074-20061010-C00036.png)
CA (1) CA2384645A1 (US07119074-20061010-C00036.png)
CZ (1) CZ2002928A3 (US07119074-20061010-C00036.png)
HU (1) HUP0204110A3 (US07119074-20061010-C00036.png)
IL (1) IL148558A0 (US07119074-20061010-C00036.png)
MX (1) MXPA02002712A (US07119074-20061010-C00036.png)
NO (1) NO20021213L (US07119074-20061010-C00036.png)
NZ (1) NZ517681A (US07119074-20061010-C00036.png)
PL (1) PL354261A1 (US07119074-20061010-C00036.png)
RU (1) RU2002109595A (US07119074-20061010-C00036.png)
WO (1) WO2001019406A2 (US07119074-20061010-C00036.png)

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Also Published As

Publication number Publication date
HUP0204110A3 (en) 2003-08-28
CA2384645A1 (en) 2001-03-22
NO20021213D0 (no) 2002-03-12
IL148558A0 (en) 2002-09-12
MXPA02002712A (es) 2003-10-14
US7119074B2 (en) 2006-10-10
CN1390143A (zh) 2003-01-08
PL354261A1 (en) 2003-12-29
AU7575600A (en) 2001-04-17
EP1212099A2 (en) 2002-06-12
KR20020059398A (ko) 2002-07-12
NO20021213L (no) 2002-05-13
CZ2002928A3 (cs) 2002-09-11
RU2002109595A (ru) 2003-11-27
US6713454B1 (en) 2004-03-30
US20040180840A1 (en) 2004-09-16
WO2001019406A2 (en) 2001-03-22
BR0013948A (pt) 2002-05-14
WO2001019406A3 (en) 2002-01-17
JP2003509385A (ja) 2003-03-11
US20040253206A1 (en) 2004-12-16
HUP0204110A2 (hu) 2003-04-28

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