NZ318515A - Cyclodepsipeptide PF1022 derivatives and compositions thereof - Google Patents
Cyclodepsipeptide PF1022 derivatives and compositions thereofInfo
- Publication number
- NZ318515A NZ318515A NZ318515A NZ31851596A NZ318515A NZ 318515 A NZ318515 A NZ 318515A NZ 318515 A NZ318515 A NZ 318515A NZ 31851596 A NZ31851596 A NZ 31851596A NZ 318515 A NZ318515 A NZ 318515A
- Authority
- NZ
- New Zealand
- Prior art keywords
- aminoalkoxy
- cyclic
- amino
- optionally
- substituted
- Prior art date
Links
- 108010002156 Depsipeptides Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- -1 thiocarbamoylalkoxy Chemical group 0.000 abstract 12
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 6
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 6
- 125000002431 aminoalkoxy group Chemical group 0.000 abstract 6
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 6
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 6
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 4
- 125000004122 cyclic group Chemical group 0.000 abstract 4
- 125000001475 halogen functional group Chemical group 0.000 abstract 4
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000001589 carboacyl group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005159 cyanoalkoxy group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 2
- 150000003222 pyridines Chemical class 0.000 abstract 2
- 150000005326 tetrahydropyrimidines Chemical class 0.000 abstract 2
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24405195 | 1995-09-22 | ||
| PCT/JP1996/002730 WO1997011064A1 (en) | 1995-09-22 | 1996-09-20 | Novel cyclic depsipeptide pf1022 derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ318515A true NZ318515A (en) | 2000-05-26 |
Family
ID=17113003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ318515A NZ318515A (en) | 1995-09-22 | 1996-09-20 | Cyclodepsipeptide PF1022 derivatives and compositions thereof |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6329338B1 (enExample) |
| EP (1) | EP0903347B1 (enExample) |
| KR (1) | KR19990063676A (enExample) |
| CN (1) | CN1082051C (enExample) |
| AT (1) | ATE299871T1 (enExample) |
| AU (1) | AU727532B2 (enExample) |
| BR (1) | BR9610527A (enExample) |
| CA (1) | CA2232668C (enExample) |
| CZ (1) | CZ295705B6 (enExample) |
| DE (1) | DE69634961T2 (enExample) |
| DK (1) | DK0903347T3 (enExample) |
| ES (1) | ES2246496T3 (enExample) |
| HU (1) | HU228004B1 (enExample) |
| IL (1) | IL123776A (enExample) |
| NO (1) | NO310622B1 (enExample) |
| NZ (1) | NZ318515A (enExample) |
| PL (1) | PL186168B1 (enExample) |
| WO (1) | WO1997011064A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0930304A4 (en) * | 1996-08-07 | 2000-03-01 | Meiji Seika Co | METHOD FOR PRODUCING CYCLODEPSIPEPTID COMPOUNDS AND CYCLODEPSIPEPTID |
| AU6229898A (en) * | 1997-02-19 | 1998-09-09 | Bayer Aktiengesellschaft | Derivatives of cyclodepsipeptide, pf1022 substance |
| DE19811559A1 (de) * | 1998-03-17 | 1999-09-23 | Bayer Ag | Cyclooctadepsipeptide |
| AU783603B2 (en) | 1999-09-29 | 2005-11-10 | Meiji Seika Kaisha Ltd. | Transformant producing secondary metabolite modified with functional group and novel biosynthesis genes |
| DE10031044A1 (de) * | 2000-06-26 | 2002-01-03 | Bayer Ag | Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere |
| DE10104362A1 (de) * | 2001-02-01 | 2002-08-08 | Bayer Ag | Kristallmodifikation eines cyclischen Depsipeptids mit besserer Wirksamkeit |
| DE102004055316A1 (de) * | 2004-11-16 | 2006-05-18 | Bayer Healthcare Ag | Verhinderung vertikaler Endoparasiten-Infektionen |
| DE102008022520A1 (de) | 2008-05-07 | 2009-11-12 | Bayer Animal Health Gmbh | Feste Arzneimittelformulierung mit verzögerter Freisetzung |
| DE102008030764A1 (de) * | 2008-06-28 | 2009-12-31 | Bayer Animal Health Gmbh | Kombination von Amidin-Derivaten mit cyclischen Depsipeptiden |
| DE102008031284A1 (de) | 2008-07-02 | 2010-01-07 | Bayer Schering Pharma Aktiengesellschaft | Neue Bekämpfungsmöglichkeit der Giardiose |
| DE102008031283A1 (de) * | 2008-07-02 | 2010-01-07 | Bayer Schering Pharma Aktiengesellschaft | Neue Bekämpfungsmöglichkeit von durch Trichomonadida hervorgerufenen Krankheiten |
| DE102009012423A1 (de) | 2009-03-10 | 2010-09-16 | Bayer Animal Health Gmbh | Zubereitung auf Ölbasis |
| DE102010064245A1 (de) | 2010-12-28 | 2012-06-28 | Bayer Animal Health Gmbh | Makrocylischen Lactone und deren Verwendung und deren Kombinationen mit anderen Wirkstoffen |
| WO2012028556A1 (en) | 2010-08-31 | 2012-03-08 | Bayer Animal Health Gmbh | Macrocyclic lactones and their use and their combinations with other active substances |
| DK3298027T3 (da) | 2015-05-20 | 2021-08-09 | Boehringer Ingelheim Animal Health Usa Inc | Anthelmintiske depsipeptidforbindelser |
| JP6943859B2 (ja) | 2015-12-28 | 2021-10-06 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 駆虫性デプシペプチド化合物 |
| MX2019005628A (es) | 2016-11-16 | 2019-12-18 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos depsipeptidos antihelminticos. |
| DK3676265T3 (da) | 2017-11-07 | 2025-09-29 | Elanco Animal Health Gmbh | Fremgangsmåde til syntese af cykliske depsipeptider |
| RU2747149C9 (ru) | 2017-11-29 | 2021-06-29 | ЗОЕТИС СЕРВИСИЗ ЭлЭлСи | Анти-эндопаразитарные депсипептиды |
| WO2019217449A1 (en) | 2018-05-10 | 2019-11-14 | Zoetis Services Llc | Endoparasitic depsipeptides |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH459977A (de) * | 1965-05-18 | 1968-07-31 | Agripat Sa | Verfahren zur Herstellung von neuen Thiocarbaminsäureestern |
| EP0103895A3 (en) * | 1982-09-22 | 1985-07-03 | Meiji Seika Kabushiki Kaisha | Novel hydroxylamine derivatives, production and use thereof |
| NO176766C (no) * | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet |
| ES2166359T3 (es) * | 1992-03-17 | 2002-04-16 | Fujisawa Pharmaceutical Co | Derivado de depsipeptido, su produccion y uso. |
| JP2873894B2 (ja) * | 1992-10-19 | 1999-03-24 | 明治製菓株式会社 | 環状デプシペプチドおよびその製造法 |
| AU695021B2 (en) * | 1993-02-19 | 1998-08-06 | Meiji Seika Kaisha Ltd. | PF1022 derivative cyclic depsipeptide |
| DE4317457A1 (de) * | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| DE4317432A1 (de) * | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| JPH07233068A (ja) * | 1993-12-27 | 1995-09-05 | Meiji Seika Kaisha Ltd | 高コレステロール血症、高脂血症又は動脈硬化症の治療薬 |
-
1996
- 1996-09-20 DK DK96931283T patent/DK0903347T3/da active
- 1996-09-20 EP EP96931283A patent/EP0903347B1/en not_active Expired - Lifetime
- 1996-09-20 CN CN96198101A patent/CN1082051C/zh not_active Expired - Lifetime
- 1996-09-20 US US09/043,558 patent/US6329338B1/en not_active Expired - Lifetime
- 1996-09-20 PL PL96326024A patent/PL186168B1/pl unknown
- 1996-09-20 DE DE69634961T patent/DE69634961T2/de not_active Expired - Lifetime
- 1996-09-20 BR BR9610527-5A patent/BR9610527A/pt not_active Application Discontinuation
- 1996-09-20 WO PCT/JP1996/002730 patent/WO1997011064A1/ja not_active Ceased
- 1996-09-20 AU AU70019/96A patent/AU727532B2/en not_active Expired
- 1996-09-20 ES ES96931283T patent/ES2246496T3/es not_active Expired - Lifetime
- 1996-09-20 KR KR1019980702138A patent/KR19990063676A/ko not_active Ceased
- 1996-09-20 NZ NZ318515A patent/NZ318515A/xx not_active IP Right Cessation
- 1996-09-20 CA CA2232668A patent/CA2232668C/en not_active Expired - Lifetime
- 1996-09-20 HU HU0001164A patent/HU228004B1/hu unknown
- 1996-09-20 AT AT96931283T patent/ATE299871T1/de active
- 1996-09-20 IL IL12377696A patent/IL123776A/en not_active IP Right Cessation
- 1996-09-20 CZ CZ1998855A patent/CZ295705B6/cs not_active IP Right Cessation
-
1998
- 1998-03-19 NO NO19981250A patent/NO310622B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU727532B2 (en) | 2000-12-14 |
| ATE299871T1 (de) | 2005-08-15 |
| KR19990063676A (ko) | 1999-07-26 |
| CN1201456A (zh) | 1998-12-09 |
| CA2232668A1 (en) | 1997-03-27 |
| ES2246496T3 (es) | 2006-02-16 |
| IL123776A0 (en) | 1998-10-30 |
| BR9610527A (pt) | 1999-12-21 |
| EP0903347B1 (en) | 2005-07-20 |
| US6329338B1 (en) | 2001-12-11 |
| DK0903347T3 (da) | 2005-11-21 |
| WO1997011064A1 (en) | 1997-03-27 |
| DE69634961D1 (de) | 2005-08-25 |
| CA2232668C (en) | 2011-10-18 |
| HUP0001164A3 (en) | 2001-04-28 |
| EP0903347A4 (enExample) | 1999-03-24 |
| HUP0001164A2 (hu) | 2000-11-28 |
| EP0903347A1 (en) | 1999-03-24 |
| MX9802268A (es) | 1998-08-30 |
| HU228004B1 (en) | 2012-08-28 |
| CZ85598A3 (cs) | 1998-08-12 |
| PL326024A1 (en) | 1998-08-17 |
| NO981250L (no) | 1998-05-22 |
| CN1082051C (zh) | 2002-04-03 |
| DE69634961T2 (de) | 2006-04-20 |
| PL186168B1 (pl) | 2003-11-28 |
| NO981250D0 (no) | 1998-03-19 |
| AU7001996A (en) | 1997-04-09 |
| IL123776A (en) | 2002-09-12 |
| NO310622B1 (no) | 2001-07-30 |
| JP4001381B1 (enExample) | 2007-10-31 |
| CZ295705B6 (cs) | 2005-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| ASS | Change of ownership |
Owner name: BAYER AKTIENGESELLSCHAFT, DE Free format text: OLD OWNER(S): BAYER AKTIENGESELLSCHAFT; MEIJI SEIKA KAISHA LTD. |
|
| RENW | Renewal (renewal fees accepted) | ||
| ASS | Change of ownership |
Owner name: BAYER ANIMAL HEALTH GMBH, DE Free format text: OLD OWNER(S): BAYER AKTIENGESELLSCHAFT |
|
| RENW | Renewal (renewal fees accepted) | ||
| ASS | Change of ownership |
Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE Effective date: 20130214 |
|
| EXPY | Patent expired |