NZ202237A - 4-phenyl-quinazoline derivatives and pharmaceutical compositions - Google Patents

4-phenyl-quinazoline derivatives and pharmaceutical compositions

Info

Publication number
NZ202237A
NZ202237A NZ202237A NZ20223782A NZ202237A NZ 202237 A NZ202237 A NZ 202237A NZ 202237 A NZ202237 A NZ 202237A NZ 20223782 A NZ20223782 A NZ 20223782A NZ 202237 A NZ202237 A NZ 202237A
Authority
NZ
New Zealand
Prior art keywords
phenyl
group
formula
derivatives
quinazoline
Prior art date
Application number
NZ202237A
Other languages
English (en)
Inventor
A Hallot
K Biziere
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NZ202237A publication Critical patent/NZ202237A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
NZ202237A 1981-10-21 1982-10-20 4-phenyl-quinazoline derivatives and pharmaceutical compositions NZ202237A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8119767A FR2514765A1 (fr) 1981-10-21 1981-10-21 Nouveaux derives de la phenyl-4 quinazoline actifs sur le systeme nerveux central

Publications (1)

Publication Number Publication Date
NZ202237A true NZ202237A (en) 1985-08-30

Family

ID=9263248

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ202237A NZ202237A (en) 1981-10-21 1982-10-20 4-phenyl-quinazoline derivatives and pharmaceutical compositions

Country Status (24)

Country Link
US (1) US4499092A (fr)
EP (1) EP0079810B1 (fr)
JP (1) JPS5888369A (fr)
KR (1) KR880001077B1 (fr)
AT (1) ATE17576T1 (fr)
AU (1) AU551938B2 (fr)
CA (1) CA1236102A (fr)
CS (1) CS229692B2 (fr)
DD (1) DD210040A5 (fr)
DE (1) DE3268699D1 (fr)
DK (1) DK156063C (fr)
ES (1) ES8307226A1 (fr)
FI (1) FI73982C (fr)
FR (1) FR2514765A1 (fr)
GR (1) GR76535B (fr)
HU (1) HU187579B (fr)
IE (1) IE53653B1 (fr)
IL (1) IL66960A0 (fr)
NO (1) NO164167C (fr)
NZ (1) NZ202237A (fr)
PT (1) PT75667B (fr)
SU (1) SU1299511A3 (fr)
YU (1) YU43528B (fr)
ZA (1) ZA827516B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant
WO1994007498A1 (fr) * 1992-10-07 1994-04-14 Sumitomo Pharmaceuticals Company, Limited Composition pharmaceutique utilisee pour inhiber la production des facteurs de necrose tumorale
JPH11209350A (ja) 1998-01-26 1999-08-03 Eisai Co Ltd 含窒素複素環誘導体およびその医薬
AU2004236239A1 (en) * 2003-04-30 2004-11-18 The Institutes For Pharmaceutical Discovery, Llc Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
MXPA06005019A (es) * 2003-11-03 2006-07-06 Warner Lambert Co Nuevos inhibidores de la recaptacion de norpinefrina para el tratamiento de transtornos del sistema nervioso central.
CN101208309B (zh) * 2005-06-27 2010-12-08 弗·哈夫曼-拉罗切有限公司 氯取代的胍类化合物
US7855194B2 (en) 2006-03-27 2010-12-21 Hoffmann-La Roche Inc. Pyrimidine, quinazoline, pteridine and triazine derivatives
ES2532277T3 (es) 2006-11-22 2015-03-25 Sumitomo Chemical Company, Limited Derivados de quinazolina capaces de inhibir la señalización de citoquinina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA894239A (en) * 1972-02-29 Pfizer Inc. Nitrogen heterocycles
US3305553A (en) * 1965-10-18 1967-02-21 Parke Davis & Co 2-aminoquinazoline derivatives
US3509141A (en) * 1966-09-15 1970-04-28 Ciba Geigy Corp 2-amino-quinazolines
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives
JPS5398997A (en) * 1977-02-09 1978-08-29 Sumitomo Chem Co Ltd Fused pyridine derivertives and process for their preparation

Also Published As

Publication number Publication date
SU1299511A3 (ru) 1987-03-23
FI823580L (fi) 1983-04-22
PT75667B (fr) 1985-01-11
CA1236102A (fr) 1988-05-03
KR840001968A (ko) 1984-06-07
HU187579B (en) 1986-01-28
IE53653B1 (en) 1989-01-04
FI73982B (fi) 1987-08-31
US4499092A (en) 1985-02-12
AU8962882A (en) 1983-04-28
IL66960A0 (en) 1983-02-23
AU551938B2 (en) 1986-05-15
FR2514765A1 (fr) 1983-04-22
DD210040A5 (de) 1984-05-30
DK465182A (da) 1983-04-22
JPS5888369A (ja) 1983-05-26
NO164167C (no) 1990-09-05
YU43528B (en) 1989-08-31
KR880001077B1 (ko) 1988-06-22
ES516694A0 (es) 1983-07-01
EP0079810A1 (fr) 1983-05-25
ATE17576T1 (de) 1986-02-15
IE822447L (en) 1983-04-21
FR2514765B1 (fr) 1984-04-06
DE3268699D1 (en) 1986-03-06
FI823580A0 (fi) 1982-10-20
EP0079810B1 (fr) 1986-01-22
DK156063C (da) 1989-11-13
ES8307226A1 (es) 1983-07-01
FI73982C (fi) 1987-12-10
NO164167B (no) 1990-05-28
PT75667A (fr) 1982-11-01
ZA827516B (en) 1983-08-31
DK156063B (da) 1989-06-19
CS229692B2 (en) 1984-06-18
GR76535B (fr) 1984-08-10
NO823491L (no) 1983-04-22
YU223382A (en) 1984-10-31

Similar Documents

Publication Publication Date Title
PL164989B1 (en) Method of obtaining diamides of pyrimidin-4,6-dicarboxylic acid
KR880002234B1 (ko) 4-아닐리노피리미딘 유도체의 제조방법
US5059601A (en) Imidazolone derivatives with activity on central nervous system and antihypertensive activity, preparation methods thereof, and pharmaceutical compositions containing them
KR960000358B1 (ko) 트리아졸로피리딘 또는 트리아졸로퀴놀린의 신규 아미노알킬티오 유도체, 그의 제조방법 및 특히 진통제로서 유용한 그것이 존재하는 약제.
DK149856B (da) Fremgangsmaade til fremstilling af 1,3-di- eller 1,3,8-trisubstituerede xanthiner eller fysiologisk acceptable salte deraf
DK160045B (da) Analogifremgangsmaade til fremstilling af 4-oxo-4h-pyridooe1,2-aaapyrimidiner eller farmaceutisk acceptable syreadditionssalte eller kvaternaere ammoniumsalte deraf
NZ202237A (en) 4-phenyl-quinazoline derivatives and pharmaceutical compositions
HRP20010969A2 (en) Novel piperazinylalkylthiopyrimidine derivatives, pharmaceutical compositions containing the same, and a process for preparation of the active substance
US5135931A (en) Pyridinylpiperazine derivatives
KR910000640B1 (ko) 중추 신경계에 활성을 나타내는 복소환 화합물의 제조방법
GB2120670A (en) Piperazine derivatives
CA1249274A (fr) Derives de 2-piperazinyl-4-phenyl-quinazoline, antidepresseurs; methode de preparation et medicaments qui renferment ces composes
CA1209994A (fr) Derives de 2-piperazinyl-quinazoline, production et composes pharmaceutiques les contenant
US3736326A (en) Isoxazolopyridine carboxylic acids and esters
US3951961A (en) Xanthene and thioxanthene derivatives, compositions thereof and a method of preparation thereof
US3598825A (en) 2(4 phenyl piperazino methyl)3 quinuclidinones
US4452982A (en) Process for the preparation of nitrogen-bridgehead condensed pyrimidine compounds, and pharmaceutical compositions containing them
EP0673368B1 (fr) Nouveaux esters d'acide nicotinique
HU194233B (en) Process for preparing 3,7-diazabicyclo/3.3.1/nonane derivatives and pharmaceuticals comprising these compounds
US3912737A (en) Isoxazolopyridine carboxylic acids and esters
CS209542B2 (en) Method of making the 2,6-bis(aminoacylamino)-benzo-1,2-d:5,4-d-bisthiazole and 2-amino-6-(aminoacylamino)-benzo 1,2-d:5,4-d-bisthiazole derivatives
US4581357A (en) Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound
HU184253B (en) Process for producing 4-amino-3-quinoline carboxylic acids and esters
KR20010013274A (ko) 2-(4-(4-(4,5-디클로로-2-메틸이미다졸-1-일)부틸)-1-피페라지닐)-5-플루오로피리미딘, 이것의 제조 방법 및 이것의치료적 용도
FI74004C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara piperazinylpyrido/2,3-b/- och -/3,4-b/ pyrazinderivat.