NO996512L - Fremgangsmåte for å forsterke ekkogeniteten og redusere dempningen til mikroinnkapslede gasser - Google Patents

Fremgangsmåte for å forsterke ekkogeniteten og redusere dempningen til mikroinnkapslede gasser

Info

Publication number
NO996512L
NO996512L NO996512A NO996512A NO996512L NO 996512 L NO996512 L NO 996512L NO 996512 A NO996512 A NO 996512A NO 996512 A NO996512 A NO 996512A NO 996512 L NO996512 L NO 996512L
Authority
NO
Norway
Prior art keywords
microparticles
diameter
polymers
imaging
applications
Prior art date
Application number
NO996512A
Other languages
English (en)
Other versions
NO316614B1 (no
NO996512D0 (no
Inventor
Charles C Church
Howard Bernstein
Julie Ann Straub
Henry T Brush
Original Assignee
Acusphere Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acusphere Inc filed Critical Acusphere Inc
Publication of NO996512D0 publication Critical patent/NO996512D0/no
Publication of NO996512L publication Critical patent/NO996512L/no
Publication of NO316614B1 publication Critical patent/NO316614B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/481—Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Acoustics & Sound (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicinal Preparation (AREA)
  • Drying Of Gases (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
NO996512A 1997-06-30 1999-12-28 Fremgangsmåte for å forsterke ekkogeniteten og redusere dempningen i mikroinnkapslede gasser NO316614B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/885,933 US6045777A (en) 1997-06-30 1997-06-30 Method for enhancing the echogenicity and decreasing the attenuation of microencapsulated gases
PCT/US1998/013514 WO1999000149A1 (en) 1997-06-30 1998-06-30 Method for enhancing the echogenicity and decreasing the attenuation of microencapsulated gases

Publications (3)

Publication Number Publication Date
NO996512D0 NO996512D0 (no) 1999-12-28
NO996512L true NO996512L (no) 2000-02-29
NO316614B1 NO316614B1 (no) 2004-03-08

Family

ID=25388026

Family Applications (1)

Application Number Title Priority Date Filing Date
NO996512A NO316614B1 (no) 1997-06-30 1999-12-28 Fremgangsmåte for å forsterke ekkogeniteten og redusere dempningen i mikroinnkapslede gasser

Country Status (22)

Country Link
US (1) US6045777A (no)
EP (1) EP0996470B1 (no)
JP (1) JP2002507214A (no)
KR (1) KR100637022B1 (no)
CN (1) CN1268397C (no)
AT (1) ATE352322T1 (no)
AU (1) AU740728B2 (no)
BR (1) BR9810371A (no)
CA (1) CA2294199C (no)
CY (1) CY1107593T1 (no)
DE (1) DE69836961T2 (no)
DK (1) DK0996470T3 (no)
ES (1) ES2280094T3 (no)
HK (1) HK1029273A1 (no)
IL (1) IL133595A (no)
MY (1) MY122120A (no)
NO (1) NO316614B1 (no)
NZ (1) NZ501830A (no)
PT (1) PT996470E (no)
TW (1) TW360521B (no)
WO (1) WO1999000149A1 (no)
ZA (1) ZA985705B (no)

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IT239807Y1 (it) * 1996-09-11 2001-03-13 Lgl Electronics Spa Dispositivo perfezionato di separazione delle spire di filato perapparecchi alimentatori di trama
GB2340040B (en) * 1997-04-30 2001-11-28 Point Biomedical Corp Microparticles useful as ultrasonic contrast agents and for delivery of drugs into the bloodstream
JP2002527410A (ja) * 1998-10-12 2002-08-27 マリンクロッド・インコーポレイテッド 新規超音波造影剤
AU6636000A (en) 1999-08-13 2001-03-13 Point Biomedical Corporation Hollow microspheres with controlled fragility for medical use
US6626854B2 (en) 2000-12-27 2003-09-30 Insightec - Txsonics Ltd. Systems and methods for ultrasound assisted lipolysis
US6645162B2 (en) 2000-12-27 2003-11-11 Insightec - Txsonics Ltd. Systems and methods for ultrasound assisted lipolysis
AU2002315505B2 (en) 2001-06-29 2008-01-17 Medgraft Microtech, Inc. Biodegradable injectable implants and related methods of manufacture and use
US20030215394A1 (en) * 2002-05-17 2003-11-20 Short Robert E. Microparticles having a matrix interior useful for ultrasound triggered delivery of drugs into the bloodstream
US6919068B2 (en) * 2002-05-17 2005-07-19 Point Biomedical Corporation Method of preparing gas-filled polymer matrix microparticles useful for echographic imaging
US20040185108A1 (en) * 2003-03-18 2004-09-23 Short Robert E. Method of preparing gas-filled polymer matrix microparticles useful for delivering drug
AU2004285595A1 (en) 2003-10-31 2005-05-12 Point Biomedical Corporation Reconstitutable microsphere compositions useful as ultrasonic contrast agents
DE602005012950D1 (de) * 2004-05-27 2009-04-09 Medtronic Inc Medizinprodukt mit einem biologischen wirkstoff
BRPI0418879A (pt) * 2004-06-04 2007-11-27 Acusphere Inc formulação de dosagem por agente de constrate pelo ultra-som
EP1609483B1 (en) * 2004-06-04 2010-03-24 Acusphere, Inc. Ultrasound contrast agent dosage formulation
US8012457B2 (en) * 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
EP1714642A1 (en) * 2005-04-18 2006-10-25 Bracco Research S.A. Pharmaceutical composition comprising gas-filled microcapsules for ultrasound mediated delivery
WO2007022074A2 (en) * 2005-08-11 2007-02-22 Perkinelmer Las, Inc. Assay particles and methods of use
US7955281B2 (en) * 2006-09-07 2011-06-07 Nivasonix, Llc External ultrasound lipoplasty
US8262591B2 (en) * 2006-09-07 2012-09-11 Nivasonix, Llc External ultrasound lipoplasty
US8697098B2 (en) 2011-02-25 2014-04-15 South Dakota State University Polymer conjugated protein micelles
KR101061224B1 (ko) * 2008-10-08 2011-08-31 포항공과대학교 산학협력단 Ｘ 선을 이용한 유동정보 측정용 캡슐
WO2011024074A2 (en) 2009-08-26 2011-03-03 Insightec Ltd. Asymmetric phased-array ultrasound transducer
EP2489034B1 (en) 2009-10-14 2016-11-30 Insightec Ltd. Mapping ultrasound transducers
US8331194B1 (en) * 2010-04-26 2012-12-11 The United States Of America As Represented By The Secretary Of The Navy Underwater acoustic waveguide
US9852727B2 (en) 2010-04-28 2017-12-26 Insightec, Ltd. Multi-segment ultrasound transducers
AU2012222142B2 (en) 2011-02-25 2017-01-12 South Dakota State University Polymer conjugated protein micelles
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
JP2011140527A (ja) * 2011-04-20 2011-07-21 Acusphere Inc 超音波造影剤の投薬処方物
WO2013151682A1 (en) 2012-04-06 2013-10-10 Children's Medical Center Corporation Process for forming microbubbles with high oxygen content and uses thereof
US20160067276A1 (en) * 2013-03-15 2016-03-10 Children's Medical Center Corporation Hollow particles encapsulating a biological gas and methods of use
WO2014144364A1 (en) 2013-03-15 2014-09-18 Children's Medical Center Corporation Gas-filled stabilized particles and methods of use
WO2015156359A1 (ja) * 2014-04-10 2015-10-15 シャープ株式会社 粘性気泡液およびその製造方法、その製造装置、その保管方法
CN107952085A (zh) * 2016-10-17 2018-04-24 北京凯莱天成医药科技有限公司 一种超声造影剂及其制备方法和用途
WO2018160752A1 (en) 2017-02-28 2018-09-07 Children's Medical Center Corporation Stimuli-responsive particles encapsulating a gas and methods of use

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US4276885A (en) * 1979-05-04 1981-07-07 Rasor Associates, Inc Ultrasonic image enhancement
US5352435A (en) * 1989-12-22 1994-10-04 Unger Evan C Ionophore containing liposomes for ultrasound imaging
US5123414A (en) * 1989-12-22 1992-06-23 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
US5334381A (en) * 1989-12-22 1994-08-02 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
GB9107628D0 (en) * 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
US5558857A (en) * 1991-06-03 1996-09-24 Nycomed Imaging As Contrast agents
DE4219723A1 (de) * 1992-06-13 1993-12-16 Schering Ag Mikropartikel, Verfahren zu deren Herstellung, sowie die Verwendung dieser in der Diagnostik
GB9221329D0 (en) * 1992-10-10 1992-11-25 Delta Biotechnology Ltd Preparation of further diagnostic agents
ES2219646T5 (es) * 1993-02-22 2008-11-01 Abraxis Bioscience, Inc. Metodos para la administracion in vivo de compuestos biologicos y composiciones utiles para los mismos.
US5565215A (en) * 1993-07-23 1996-10-15 Massachusettes Institute Of Technology Biodegradable injectable particles for imaging
NO940711D0 (no) * 1994-03-01 1994-03-01 Nycomed Imaging As Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging
US5562893A (en) * 1994-08-02 1996-10-08 Molecular Biosystems, Inc. Gas-filled microspheres with fluorine-containing shells
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US5611344A (en) * 1996-03-05 1997-03-18 Acusphere, Inc. Microencapsulated fluorinated gases for use as imaging agents

Also Published As

Publication number Publication date
IL133595A (en) 2004-06-01
KR20010014300A (ko) 2001-02-26
NZ501830A (en) 2003-01-31
AU740728B2 (en) 2001-11-15
US6045777A (en) 2000-04-04
CY1107593T1 (el) 2013-03-13
CA2294199A1 (en) 1999-01-07
EP0996470B1 (en) 2007-01-24
ATE352322T1 (de) 2007-02-15
NO316614B1 (no) 2004-03-08
DK0996470T3 (da) 2007-05-21
KR100637022B1 (ko) 2006-10-20
WO1999000149A1 (en) 1999-01-07
AU8273198A (en) 1999-01-19
CA2294199C (en) 2009-01-20
PT996470E (pt) 2007-03-30
CN1261809A (zh) 2000-08-02
JP2002507214A (ja) 2002-03-05
EP0996470A1 (en) 2000-05-03
ZA985705B (en) 1999-08-04
ES2280094T3 (es) 2007-09-01
DE69836961T2 (de) 2007-10-18
TW360521B (en) 1999-06-11
HK1029273A1 (en) 2001-03-30
NO996512D0 (no) 1999-12-28
MY122120A (en) 2006-03-31
IL133595A0 (en) 2001-04-30
BR9810371A (pt) 2000-09-05
CN1268397C (zh) 2006-08-09
DE69836961D1 (de) 2007-03-15

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