WO1996040277A3 - Spray dried polymeric microparticles containing imaging agents - Google Patents
Spray dried polymeric microparticles containing imaging agents Download PDFInfo
- Publication number
- WO1996040277A3 WO1996040277A3 PCT/US1996/008378 US9608378W WO9640277A3 WO 1996040277 A3 WO1996040277 A3 WO 1996040277A3 US 9608378 W US9608378 W US 9608378W WO 9640277 A3 WO9640277 A3 WO 9640277A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- microparticles
- imaging
- polymer
- spray dried
- microspheres
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 7
- 239000012216 imaging agent Substances 0.000 title abstract 4
- 239000007921 spray Substances 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 3
- 238000002059 diagnostic imaging Methods 0.000 abstract 2
- 238000003384 imaging method Methods 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 239000004005 microsphere Substances 0.000 abstract 2
- 239000000227 bioadhesive Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 238000002594 fluoroscopy Methods 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 238000002595 magnetic resonance imaging Methods 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 229920001059 synthetic polymer Polymers 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
- 238000003325 tomography Methods 0.000 abstract 1
- 238000012285 ultrasound imaging Methods 0.000 abstract 1
- 210000003462 vein Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU63780/96A AU6378096A (en) | 1995-06-07 | 1996-06-03 | Spray dried polymeric microparticles containing imaging agen ts |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48777595A | 1995-06-07 | 1995-06-07 | |
US487,775 | 1995-06-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1996040277A2 WO1996040277A2 (en) | 1996-12-19 |
WO1996040277A3 true WO1996040277A3 (en) | 1997-05-01 |
Family
ID=23937074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1996/008378 WO1996040277A2 (en) | 1995-06-07 | 1996-06-03 | Spray dried polymeric microparticles containing imaging agents |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU6378096A (en) |
WO (1) | WO1996040277A2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9421166B2 (en) | 2001-12-19 | 2016-08-23 | Novartis Ag | Pulmonary delivery of aminoglycoside |
US9439862B2 (en) | 2000-05-10 | 2016-09-13 | Novartis Ag | Phospholipid-based powders for drug delivery |
US9554993B2 (en) | 1997-09-29 | 2017-01-31 | Novartis Ag | Pulmonary delivery particles comprising an active agent |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ331460A (en) * | 1996-03-05 | 1998-12-23 | Acusphere Inc | Microencapsulated fluorinated gases for use as imaging agents |
EP0963209A2 (en) * | 1996-10-28 | 1999-12-15 | Marsden, John Christopher | Improvements in or relating to diagnostic/therapeutic agents |
US6261537B1 (en) | 1996-10-28 | 2001-07-17 | Nycomed Imaging As | Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors |
CN1234742A (en) | 1996-10-28 | 1999-11-10 | 奈科姆成像有限公司 | Improvements in or relating to diagnostic/therapeutic agents and improvement relating to same |
US6331289B1 (en) | 1996-10-28 | 2001-12-18 | Nycomed Imaging As | Targeted diagnostic/therapeutic agents having more than one different vectors |
DE19813174A1 (en) * | 1998-03-25 | 1999-05-27 | Schering Ag | Gas-filled microparticles, used for administering biologically active substances |
WO2004105802A1 (en) * | 2003-05-27 | 2004-12-09 | Philips Intellectual Property & Standards Gmbh | Tracer for medical imaging |
GB2519738A (en) * | 2013-09-06 | 2015-05-06 | Biocompatibles Uk Ltd | Radiopaque polymers |
CN104399091B (en) * | 2014-10-31 | 2017-06-13 | 苏州大学 | Ultrasound/magnetic resonance bimodal contrast agent, its preparation method and application |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0458079A2 (en) * | 1990-04-26 | 1991-11-27 | Hoechst Aktiengesellschaft | Ultrasonic contrast agent, its preparation and application as diagnostic or therapeutic |
EP0458745A1 (en) * | 1990-05-18 | 1991-11-27 | BRACCO International B.V. | Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography |
WO1992017514A1 (en) * | 1991-04-05 | 1992-10-15 | Unger Evan C | Low density microspheres and their use as contrast agents for computed tomography |
WO1992018164A1 (en) * | 1991-04-10 | 1992-10-29 | Delta Biotechnology Limited | Preparation of diagnostic agents |
EP0535387A1 (en) * | 1991-09-03 | 1993-04-07 | Hoechst Aktiengesellschaft | Echographique particle, preparation and application |
WO1994008627A1 (en) * | 1992-10-10 | 1994-04-28 | Andaris Limited | Preparation of further diagnostic agents |
-
1996
- 1996-06-03 WO PCT/US1996/008378 patent/WO1996040277A2/en active Application Filing
- 1996-06-03 AU AU63780/96A patent/AU6378096A/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0458079A2 (en) * | 1990-04-26 | 1991-11-27 | Hoechst Aktiengesellschaft | Ultrasonic contrast agent, its preparation and application as diagnostic or therapeutic |
EP0458745A1 (en) * | 1990-05-18 | 1991-11-27 | BRACCO International B.V. | Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography |
WO1992017514A1 (en) * | 1991-04-05 | 1992-10-15 | Unger Evan C | Low density microspheres and their use as contrast agents for computed tomography |
WO1992018164A1 (en) * | 1991-04-10 | 1992-10-29 | Delta Biotechnology Limited | Preparation of diagnostic agents |
EP0535387A1 (en) * | 1991-09-03 | 1993-04-07 | Hoechst Aktiengesellschaft | Echographique particle, preparation and application |
WO1994008627A1 (en) * | 1992-10-10 | 1994-04-28 | Andaris Limited | Preparation of further diagnostic agents |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9554993B2 (en) | 1997-09-29 | 2017-01-31 | Novartis Ag | Pulmonary delivery particles comprising an active agent |
US9439862B2 (en) | 2000-05-10 | 2016-09-13 | Novartis Ag | Phospholipid-based powders for drug delivery |
US9421166B2 (en) | 2001-12-19 | 2016-08-23 | Novartis Ag | Pulmonary delivery of aminoglycoside |
Also Published As
Publication number | Publication date |
---|---|
WO1996040277A2 (en) | 1996-12-19 |
AU6378096A (en) | 1996-12-30 |
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