NO994919L - FremgangsmÕte ved syntetisering av fosfidiesterforbindelser - Google Patents

FremgangsmÕte ved syntetisering av fosfidiesterforbindelser

Info

Publication number
NO994919L
NO994919L NO994919A NO994919A NO994919L NO 994919 L NO994919 L NO 994919L NO 994919 A NO994919 A NO 994919A NO 994919 A NO994919 A NO 994919A NO 994919 L NO994919 L NO 994919L
Authority
NO
Norway
Prior art keywords
phosphidic
synthesis
alcohol
reaction
ester compounds
Prior art date
Application number
NO994919A
Other languages
English (en)
Other versions
NO994919D0 (no
NO325619B1 (no
Inventor
John C Amedio
Paul J Bernard
Mark Fountain
Original Assignee
Epix Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epix Medical Inc filed Critical Epix Medical Inc
Publication of NO994919D0 publication Critical patent/NO994919D0/no
Publication of NO994919L publication Critical patent/NO994919L/no
Publication of NO325619B1 publication Critical patent/NO325619B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
NO19994919A 1997-04-11 1999-10-08 Fremgangsmate ved syntetisering av fosfodiesterforbindelser NO325619B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/833,745 US5919967A (en) 1997-04-11 1997-04-11 Process for synthesizing phosphodiesters
PCT/US1998/001473 WO1998046612A1 (en) 1997-04-11 1998-01-27 Process for synthesizing phosphodiesters

Publications (3)

Publication Number Publication Date
NO994919D0 NO994919D0 (no) 1999-10-08
NO994919L true NO994919L (no) 1999-10-08
NO325619B1 NO325619B1 (no) 2008-06-30

Family

ID=25265165

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19994919A NO325619B1 (no) 1997-04-11 1999-10-08 Fremgangsmate ved syntetisering av fosfodiesterforbindelser

Country Status (21)

Country Link
US (1) US5919967A (no)
EP (1) EP1021452B1 (no)
JP (2) JP4014231B2 (no)
KR (2) KR20060066122A (no)
AT (1) ATE236171T1 (no)
AU (1) AU728902B2 (no)
BR (1) BR9809084B1 (no)
CA (1) CA2285417C (no)
CZ (1) CZ294469B6 (no)
DE (1) DE69812983T2 (no)
DK (1) DK1021452T3 (no)
ES (1) ES2195315T3 (no)
HU (1) HU224257B1 (no)
IL (1) IL131964A (no)
IS (1) IS1994B (no)
NO (1) NO325619B1 (no)
NZ (1) NZ337921A (no)
PL (1) PL188258B1 (no)
PT (1) PT1021452E (no)
SK (1) SK283832B6 (no)
WO (1) WO1998046612A1 (no)

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IL134985A0 (en) 1997-10-02 2001-05-20 Epix Medical Inc A method for contrast enhanced diagnostic imaging
US20030203879A1 (en) * 1999-09-09 2003-10-30 Schering Ag Calcium complex of [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.O)methyl]-1-[(4,4-diphenylcyclohexy)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.N6,.Kappa.N9,.Kappa 011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents
DE19964224B4 (de) * 1999-09-09 2005-09-01 Schering Ag Pharmazeutische Mittel enthaltend Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6,.kappa.N9,.kappa.011]1-oxidato(6-)]-, tetrahydrogen (MS-325) und dessen Salze sowie Verfahren zur Herstellung der Mittel
US6559330B1 (en) * 1999-09-09 2003-05-06 Schering Aktiengesellschaft Calcium complex of [[(4r)-4-[bis{carboxy-.kappa.o)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.o)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.n6,.kappa.n9,.kappa.011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents
WO2003029257A1 (de) * 2001-09-27 2003-04-10 Schering Aktiengesellschaft (ethylen)-(propylen/butylen)-phosphodiester-triaminpentaessigsäure-derivate
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
JP2006514915A (ja) 2002-03-01 2006-05-18 ダイアックス、コープ Ｋｄｒおよびｖｅｇｆ／ｋｄｒ結合ペプチドならびに診断および治療におけるその使用
EP1587944A4 (en) 2002-03-01 2007-03-21 Dyax Corp KDR AND VEGF / KDR BINDING PEPTIDES AND THEIR USE FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
SI2949658T1 (sl) 2003-03-03 2018-10-30 Dyax Corp. Peptidi, ki specifično vežejo HGF receptor (cMet) in njihove uporabe
KR100585219B1 (ko) * 2004-05-07 2006-06-01 주식회사 태평양 포스페이트 유도체 및 이의 제조방법
CN100487093C (zh) * 2006-03-15 2009-05-13 中国石油化工股份有限公司 一种亚磷酰胺酯类极压抗磨剂及其制备和应用
CN102356087A (zh) 2009-03-19 2012-02-15 惠氏有限责任公司 [2-(8,9-二氧代-2,6-二氮杂双环[5.2.0]壬-1(7)-烯-2-基)乙基]膦酸及其前体的制备方法
WO2010121133A2 (en) 2009-04-17 2010-10-21 The General Hospital Corporation Multimodal imaging of fibrin
TW201514188A (zh) * 2013-03-13 2015-04-16 Lantheus Medical Imaging Inc 製備釓磷維塞三鈉單水合物之方法
US20150344523A1 (en) 2014-05-05 2015-12-03 California Institute Of Technology Mutant akt-specific capture agents, compositions, and methods of using and making
US10471162B2 (en) 2014-06-20 2019-11-12 The General Hospital Corporation Collagen targeted imaging probes
CN107624115B (zh) 2015-03-16 2021-10-26 加州理工学院 肉毒神经毒素特异性捕获剂、组合物、使用方法和制造方法
EP3322716A2 (en) 2015-07-15 2018-05-23 California Institute of Technology Il-17f-specific capture agents, compositions, and methods of using and making
US11884707B2 (en) 2016-09-29 2024-01-30 Regeneron Pharmaceuticals, Inc. Compositions for detection, inhibition and imaging of indoleamine 2, 3-dioxygenase 1 (IDO1) and methods of making and using same
US11358982B2 (en) 2016-11-01 2022-06-14 Ohio State Innovation Foundation Methods for the iodination of biomolecules
EP3638687A1 (en) 2017-06-15 2020-04-22 Indi Molecular, Inc. Il-17f and il-17a-specific capture agents, compositions, and methods of using and making
US11919972B2 (en) 2018-11-02 2024-03-05 Regeneron Pharmaceuticals, Inc. Peptide libraries with non-canonical amino acids
US11638764B2 (en) 2018-11-08 2023-05-02 Indi Molecular, Inc. Theranostic capture agents, compositions, and methods of using and making
US11414460B2 (en) 2019-07-19 2022-08-16 Institute For Systems Biology KRAS-specific capture agents, compositions, and methods of making and using
WO2022098743A1 (en) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1)
WO2022098745A1 (en) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, delivery systems, and methods useful in tumor therapy
WO2022185843A1 (ja) * 2021-03-03 2022-09-09 国立大学法人東京工業大学 非対称型リン酸トリエステルの製造方法、対称型リン酸トリエステルの製造方法、リン酸エステルの製造方法、及び、有機リン化合物の製造方法

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US4647447A (en) * 1981-07-24 1987-03-03 Schering Aktiengesellschaft Diagnostic media
US4880008A (en) * 1985-05-08 1989-11-14 The General Hospital Corporation Vivo enhancement of NMR relaxivity
TW319763B (no) * 1995-02-01 1997-11-11 Epix Medical Inc
WO1996027379A1 (en) * 1995-03-08 1996-09-12 The Scripps Research Institute Carbopeptoids and carbonucleotoids

Also Published As

Publication number Publication date
BR9809084A (pt) 2000-08-01
WO1998046612A1 (en) 1998-10-22
PL188258B1 (pl) 2005-01-31
JP4014231B2 (ja) 2007-11-28
NO994919D0 (no) 1999-10-08
IS5193A (is) 1999-09-24
HUP0004239A2 (en) 2001-03-28
HUP0004239A3 (en) 2001-11-28
EP1021452B1 (en) 2003-04-02
PL337423A1 (en) 2000-08-14
ES2195315T3 (es) 2003-12-01
DE69812983D1 (de) 2003-05-08
IL131964A (en) 2004-01-04
EP1021452A1 (en) 2000-07-26
AU6042598A (en) 1998-11-11
IL131964A0 (en) 2001-03-19
SK283832B6 (sk) 2004-02-03
BR9809084B1 (pt) 2010-12-14
JP2002511060A (ja) 2002-04-09
CZ355999A3 (cs) 2000-01-12
KR20010006177A (ko) 2001-01-26
KR100593650B1 (ko) 2006-07-03
NZ337921A (en) 2000-09-29
DE69812983T2 (de) 2004-01-08
DK1021452T3 (da) 2003-08-18
US5919967A (en) 1999-07-06
PT1021452E (pt) 2003-08-29
KR20060066122A (ko) 2006-06-15
HU224257B1 (hu) 2005-07-28
IS1994B (is) 2005-03-15
CZ294469B6 (cs) 2005-01-12
ATE236171T1 (de) 2003-04-15
CA2285417A1 (en) 1998-10-22
AU728902B2 (en) 2001-01-18
JP2005206605A (ja) 2005-08-04
SK138299A3 (en) 2000-05-16
CA2285417C (en) 2006-01-24
NO325619B1 (no) 2008-06-30

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