NO993706D0 - Pyrrolidinderivater med fosfolipase A2 inhiberende aktivitet - Google Patents
Pyrrolidinderivater med fosfolipase A2 inhiberende aktivitetInfo
- Publication number
- NO993706D0 NO993706D0 NO993706A NO993706A NO993706D0 NO 993706 D0 NO993706 D0 NO 993706D0 NO 993706 A NO993706 A NO 993706A NO 993706 A NO993706 A NO 993706A NO 993706 D0 NO993706 D0 NO 993706D0
- Authority
- NO
- Norway
- Prior art keywords
- phospholipase
- inhibitory activity
- optionally substituted
- pyrrolidine derivatives
- ch2nhco
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1796297 | 1997-01-31 | ||
| PCT/JP1998/000307 WO1998033797A1 (fr) | 1997-01-31 | 1998-01-27 | Derives de pyrrolidine ayant une activite inhibant la phospholipase a2 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO993706D0 true NO993706D0 (no) | 1999-07-29 |
| NO993706L NO993706L (no) | 1999-09-30 |
| NO313881B1 NO313881B1 (no) | 2002-12-16 |
Family
ID=11958379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19993706A NO313881B1 (no) | 1997-01-31 | 1999-07-29 | Pyrrolidinderivater med fosfolipase A2 inhiberende aktivitet, og preparater inneholdende slike forbindelser |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6147100A (no) |
| EP (1) | EP0976748B1 (no) |
| JP (1) | JP3850450B2 (no) |
| KR (1) | KR100354358B1 (no) |
| CN (1) | CN1217942C (no) |
| AT (1) | ATE255579T1 (no) |
| AU (1) | AU719210B2 (no) |
| BR (1) | BR9807132A (no) |
| CA (1) | CA2277947C (no) |
| DE (1) | DE69820248T2 (no) |
| DK (1) | DK0976748T3 (no) |
| ES (1) | ES2210710T3 (no) |
| HU (1) | HUP0000965A3 (no) |
| NO (1) | NO313881B1 (no) |
| PL (1) | PL334915A1 (no) |
| PT (1) | PT976748E (no) |
| RU (1) | RU2198174C2 (no) |
| TR (1) | TR199901847T2 (no) |
| TW (1) | TW577875B (no) |
| WO (1) | WO1998033797A1 (no) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7291626B1 (en) | 1998-04-09 | 2007-11-06 | John Hopkins University School Of Medicine | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto |
| US7026334B1 (en) | 1999-07-26 | 2006-04-11 | Shionogi & Co., Ltd. | Thiazolidine compounds and pharmaceutical compositions exhibiting thrombopoietin receptor agonism |
| IL149069A0 (en) | 1999-10-13 | 2002-11-10 | Univ Johns Hopkins Med | Regulators of the hedgehog pathway, compositions and uses related thereto |
| US6552016B1 (en) | 1999-10-14 | 2003-04-22 | Curis, Inc. | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| IL148972A0 (en) * | 1999-10-14 | 2002-11-10 | Curis Inc | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| WO2001030387A1 (fr) * | 1999-10-22 | 2001-05-03 | Shionogi & Co., Ltd. | Produits prophylactiques ou de traitement contre l'arythmie |
| US7361663B2 (en) | 1999-11-10 | 2008-04-22 | Aventis Pharmaceuticals Inc. | N-acylpyrrolidin-2-ylalkylbenzamidine derivatives as inhibitors of factor Xa |
| EP1263726B1 (en) * | 1999-11-10 | 2007-09-26 | Sanofi-Aventis Deutschland GmbH | N-acylpyrrolidin-2-ylalkylbenzamidine derivatives as inhibitors of factor xa |
| PT1309755E (pt) * | 2000-08-07 | 2012-05-25 | Akzo Nobel Nv | Processo de encolagem de papel |
| EP1354880A4 (en) * | 2001-01-26 | 2004-08-25 | Shionogi & Co | HALOGEN COMPOUNDS HAVING AGONISM TOWARDS THROMBOPOIETIN RECEPTOR |
| US20030073945A1 (en) * | 2001-10-17 | 2003-04-17 | Liang-Kuang Diang | Ozone hemodiafiltration device |
| US6867320B2 (en) * | 2002-02-21 | 2005-03-15 | Asahi Kasei Pharma Corporation | Substituted phenylalkanoic acid derivatives and use thereof |
| US20040018533A1 (en) * | 2002-06-04 | 2004-01-29 | Adam Gail Isabel Reid | Diagnosing predisposition to fat deposition and therapeutic methods for reducing fat deposition and treatment of associated conditions |
| AUPS282602A0 (en) | 2002-06-07 | 2002-06-27 | Garvan Institute Of Medical Research | Method of inhibiting cell proliferation |
| US20050014158A1 (en) * | 2002-06-27 | 2005-01-20 | Adam Gail Isabel Reid | Therapeutic methods for reducing fat deposition and treating associated conditions |
| US20050239077A1 (en) * | 2002-06-27 | 2005-10-27 | Adam Gail I R | Diagnosing predisposition to fat deposition and associated conditions |
| US20060276520A1 (en) * | 2002-11-13 | 2006-12-07 | Rigel Pharmaceuticals, Inc. | Rhodanine derivatives and pharmaceutical compositions containing them |
| WO2004050654A1 (ja) * | 2002-11-29 | 2004-06-17 | Shionogi & Co., Ltd. | ピロリジン化合物の合成とその塩 |
| US7521465B2 (en) * | 2003-01-17 | 2009-04-21 | Bexel Pharmaceuticals, Inc. | Diphenyl ether derivatives |
| US7781464B2 (en) * | 2003-01-17 | 2010-08-24 | Bexel Pharmaceuticals, Inc. | Heterocyclic diphenyl ethers |
| US6794401B2 (en) * | 2003-01-17 | 2004-09-21 | Bexel Pharmaceuticals, Inc. | Amino acid phenoxy ethers |
| DE10305089A1 (de) * | 2003-02-07 | 2004-08-26 | Merckle Gmbh | Neue heteroarylsubstituierte Acetonderivate als Hemmstoffe der Phospholiphase A2 |
| WO2004089368A1 (ja) * | 2003-04-08 | 2004-10-21 | Shionogi & Co. Ltd. | 皮膚炎の治療または予防剤 |
| MXPA06001739A (es) | 2003-08-14 | 2006-05-12 | Asahi Kasei Pharma Corp | Derivado de acido arilalcanoico substituido y uso del mismo. |
| US7087576B2 (en) * | 2003-10-07 | 2006-08-08 | Bexel Pharmaceuticals, Inc. | Dipeptide phenyl ethers |
| US7207652B2 (en) * | 2003-10-17 | 2007-04-24 | Lexmark International, Inc. | Balanced satellite distributions |
| US20090215857A1 (en) * | 2005-09-13 | 2009-08-27 | Pfizer Products Inc. | Therapeutic Pyrrolidines |
| TWI461423B (zh) | 2008-07-02 | 2014-11-21 | Astrazeneca Ab | 用於治療Pim激酶相關病狀及疾病之噻唑啶二酮化合物 |
| CA2739919A1 (en) * | 2008-10-21 | 2010-04-29 | Merck Sharp & Dohme Corp. | 2,4-disubstituted pyrrolidine orexin receptor antagonists |
| EP2583099B1 (en) | 2010-06-18 | 2016-11-02 | Whitehead Institute for Biomedical Research | Pla2g16 as a target for antiviral compounds |
| US8772277B2 (en) | 2011-08-04 | 2014-07-08 | Takeda Pharmaceutical Company Limited | Nitrogen-containing heterocyclic compound |
| USD804651S1 (en) | 2017-01-10 | 2017-12-05 | Howard Loonan | Syringe |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2826379B2 (ja) * | 1990-01-22 | 1998-11-18 | 三共株式会社 | チアゾリジン誘導体を有効成分とする肥満性高血圧症治療剤 |
| US5317016A (en) * | 1991-08-20 | 1994-05-31 | Shionogi Seiyaku Kabushiki Kaisha | Pyrrolidylthiocarbapenem derivative |
| FR2680512B1 (fr) * | 1991-08-20 | 1995-01-20 | Adir | Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| JPH05306224A (ja) * | 1992-04-24 | 1993-11-19 | Wakamoto Pharmaceut Co Ltd | ドーパミン β−ヒドロキシラーゼ阻害剤 |
| EP0586229A1 (en) * | 1992-09-01 | 1994-03-09 | Zeneca Limited | 3-Hydroxy-3-(subst-akyl)-pyrrolidines as 5-lipoxygenase inhibitors |
| TW245716B (no) * | 1992-12-28 | 1995-04-21 | Takeda Pharm Industry Co | |
| AU684316B2 (en) * | 1993-10-15 | 1997-12-11 | Shionogi & Co., Ltd. | Oxazolinone derivative having intracellular phospholipase A2 inhibitor activity |
| JPH07138258A (ja) * | 1993-11-16 | 1995-05-30 | Taiho Yakuhin Kogyo Kk | チアゾリジンジオン誘導体又はその塩 |
| IL113084A (en) * | 1994-03-23 | 1999-01-26 | Sankyo Co | Derivatives of thiazolidine and oxazolidine, processes for their preparation and pharmaceutical preparations containing them |
| DK0848004T3 (da) * | 1995-07-31 | 2003-07-21 | Shionogi & Co | Pyrrolidinderivater med inhiberende aktivitet mod phospholipase A2 |
| JPH09176162A (ja) * | 1995-12-22 | 1997-07-08 | Toubishi Yakuhin Kogyo Kk | チアゾリジンジオン誘導体及びその製造法並びにそれを含む医薬組成物 |
| WO1997041120A1 (en) * | 1996-07-26 | 1997-11-06 | Dr. Reddy's Research Foundation | Thiazolidinedione compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions thereof |
| WO1997041121A1 (en) * | 1997-05-02 | 1997-11-06 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| EP0981526B1 (en) * | 1997-05-02 | 2004-02-25 | Dr. Reddy's Laboratories Ltd. | Novel antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
-
1998
- 1998-01-26 TW TW087101064A patent/TW577875B/zh not_active IP Right Cessation
- 1998-01-27 CA CA002277947A patent/CA2277947C/en not_active Expired - Fee Related
- 1998-01-27 KR KR1019997006741A patent/KR100354358B1/ko not_active IP Right Cessation
- 1998-01-27 BR BR9807132-7A patent/BR9807132A/pt not_active Application Discontinuation
- 1998-01-27 HU HU0000965A patent/HUP0000965A3/hu unknown
- 1998-01-27 JP JP53270898A patent/JP3850450B2/ja not_active Expired - Fee Related
- 1998-01-27 ES ES98900741T patent/ES2210710T3/es not_active Expired - Lifetime
- 1998-01-27 PL PL98334915A patent/PL334915A1/xx not_active Application Discontinuation
- 1998-01-27 PT PT98900741T patent/PT976748E/pt unknown
- 1998-01-27 WO PCT/JP1998/000307 patent/WO1998033797A1/ja active IP Right Grant
- 1998-01-27 DK DK98900741T patent/DK0976748T3/da active
- 1998-01-27 CN CN988038021A patent/CN1217942C/zh not_active Expired - Fee Related
- 1998-01-27 RU RU99119481/04A patent/RU2198174C2/ru not_active IP Right Cessation
- 1998-01-27 US US09/355,008 patent/US6147100A/en not_active Expired - Fee Related
- 1998-01-27 DE DE69820248T patent/DE69820248T2/de not_active Expired - Lifetime
- 1998-01-27 EP EP98900741A patent/EP0976748B1/en not_active Expired - Lifetime
- 1998-01-27 AT AT98900741T patent/ATE255579T1/de not_active IP Right Cessation
- 1998-01-27 TR TR1999/01847T patent/TR199901847T2/xx unknown
- 1998-01-27 AU AU55775/98A patent/AU719210B2/en not_active Ceased
-
1999
- 1999-07-29 NO NO19993706A patent/NO313881B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1251587A (zh) | 2000-04-26 |
| WO1998033797A1 (fr) | 1998-08-06 |
| JP3850450B2 (ja) | 2006-11-29 |
| CA2277947C (en) | 2004-09-21 |
| US6147100A (en) | 2000-11-14 |
| PT976748E (pt) | 2004-03-31 |
| KR100354358B1 (ko) | 2002-09-28 |
| RU2198174C2 (ru) | 2003-02-10 |
| KR20000070497A (ko) | 2000-11-25 |
| CA2277947A1 (en) | 1998-08-06 |
| ES2210710T3 (es) | 2004-07-01 |
| NO993706L (no) | 1999-09-30 |
| TW577875B (en) | 2004-03-01 |
| BR9807132A (pt) | 2000-01-25 |
| AU719210B2 (en) | 2000-05-04 |
| AU5577598A (en) | 1998-08-25 |
| DE69820248T2 (de) | 2004-09-23 |
| TR199901847T2 (xx) | 2000-06-21 |
| CN1217942C (zh) | 2005-09-07 |
| HUP0000965A2 (hu) | 2001-04-28 |
| EP0976748A1 (en) | 2000-02-02 |
| NO313881B1 (no) | 2002-12-16 |
| HUP0000965A3 (en) | 2001-11-28 |
| DE69820248D1 (de) | 2004-01-15 |
| EP0976748A4 (en) | 2001-08-08 |
| ATE255579T1 (de) | 2003-12-15 |
| PL334915A1 (en) | 2000-03-27 |
| EP0976748B1 (en) | 2003-12-03 |
| DK0976748T3 (da) | 2004-03-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0976748T3 (da) | Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet | |
| ES2182852T3 (es) | Derivados de prolinamida. | |
| PT705833E (pt) | Derivado de dc-89 | |
| HK1032969A1 (en) | Novel pyridazine derivatives and drugs containing the same as the active ingredient | |
| CA2311742A1 (en) | 6-amino-9-benzyl-8-hydroxypurine derivatives | |
| DK260588A (da) | Heterocykliske ketoner | |
| DK0641770T3 (da) | Hidtil ukendte forbindelser med blodpladeaggegationsinhiberende aktivitet | |
| ATE223411T1 (de) | 1-methylcarbapenem-derivate | |
| ATE174593T1 (de) | Neue bisoxadiazolidinderivate | |
| FI952420A (fi) | Glukopyranosidibentsotiofeenit | |
| DE60238847D1 (de) | Pyrimidinderivate enthaltendes medikament | |
| ES2149180T3 (es) | Derivado de pirazolotiazolopirimidina. |