NO991072L - Intermediater for fremstilling av HIV-protease inhibitorer og fremgangsmÕter for fremstilling av HIV-protease inhibitorer - Google Patents

Intermediater for fremstilling av HIV-protease inhibitorer og fremgangsmÕter for fremstilling av HIV-protease inhibitorer

Info

Publication number
NO991072L
NO991072L NO991072A NO991072A NO991072L NO 991072 L NO991072 L NO 991072L NO 991072 A NO991072 A NO 991072A NO 991072 A NO991072 A NO 991072A NO 991072 L NO991072 L NO 991072L
Authority
NO
Norway
Prior art keywords
preparation
protease inhibitors
hiv protease
intermediates
methods
Prior art date
Application number
NO991072A
Other languages
English (en)
Other versions
NO991072D0 (no
NO313287B1 (no
Inventor
Kathleen R Whitten
Michael E Deason
Original Assignee
Augouron Pharmaceuticals Inc
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Augouron Pharmaceuticals Inc, Japan Tobacco Inc filed Critical Augouron Pharmaceuticals Inc
Publication of NO991072L publication Critical patent/NO991072L/no
Publication of NO991072D0 publication Critical patent/NO991072D0/no
Publication of NO313287B1 publication Critical patent/NO313287B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/287—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12—Acetic acid esters
    • C07C69/14—Acetic acid esters of monohydroxylic compounds
    • C07C69/145—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
    • C07C69/157—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/63—Halogen-containing esters of saturated acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19991072A 1996-09-05 1999-03-04 Fremgangsmåter for fremstilling av HIV-protease inhibitorer NO313287B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70841196A 1996-09-05 1996-09-05
PCT/US1997/015468 WO1998009951A2 (en) 1996-09-05 1997-09-04 Intermediates for making hiv-protease inhibitors and methods of making hiv-protease inhibitors

Publications (3)

Publication Number Publication Date
NO991072L true NO991072L (no) 1999-03-04
NO991072D0 NO991072D0 (no) 1999-03-04
NO313287B1 NO313287B1 (no) 2002-09-09

Family

ID=24845703

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19991072A NO313287B1 (no) 1996-09-05 1999-03-04 Fremgangsmåter for fremstilling av HIV-protease inhibitorer

Country Status (33)

Country Link
EP (2) EP0927165B1 (no)
JP (3) JP4149000B2 (no)
KR (1) KR100563289B1 (no)
CN (2) CN1305854C (no)
AP (2) AP1322A (no)
AT (2) ATE309990T1 (no)
AU (2) AU740369B2 (no)
BG (2) BG64793B1 (no)
BR (1) BR9713192A (no)
CA (1) CA2264756A1 (no)
CZ (2) CZ298174B6 (no)
DE (2) DE69734689T2 (no)
DK (2) DK1361216T3 (no)
EA (1) EA002051B1 (no)
EE (1) EE04465B1 (no)
ES (2) ES2210573T3 (no)
GE (1) GEP20022799B (no)
HK (1) HK1062171A1 (no)
HU (1) HUP0000028A3 (no)
IL (1) IL128567A (no)
IS (1) IS2030B (no)
NO (1) NO313287B1 (no)
NZ (1) NZ334909A (no)
OA (1) OA10988A (no)
PL (2) PL198408B1 (no)
PT (1) PT927165E (no)
SG (1) SG94780A1 (no)
SI (2) SI1361216T1 (no)
SK (2) SK284899B6 (no)
TR (1) TR199900473T2 (no)
UA (1) UA67727C2 (no)
WO (1) WO1998009951A2 (no)
YU (1) YU11599A (no)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0641038A (ja) * 1992-07-17 1994-02-15 Mitsubishi Kasei Corp カルボン酸誘導体
US5484926A (en) * 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
JPH07248183A (ja) * 1994-03-11 1995-09-26 Osaka Gas Co Ltd 浴室兼用衣類乾燥室
JP3298293B2 (ja) * 1994-03-14 2002-07-02 松下電器産業株式会社 厨芥処理機
AU4953796A (en) * 1995-03-15 1996-10-02 Sanyko Company, Limited Dipeptide compounds having ahpba structure
DE69634345T2 (de) * 1995-09-26 2006-03-02 Japan Tobacco Inc. Verfahren zur herstellung von amid-derivaten und ihren zwischenverbindungen
EP0984000B1 (en) * 1995-09-26 2008-12-03 Japan Tabacco Inc. Process for producing amide derivatives and intermediate compounds
US5962704A (en) * 1995-09-26 1999-10-05 Japan Tobacco Inc. Production of amide derivatives and intermediate compounds therefor
WO1997030993A1 (de) * 1996-02-24 1997-08-28 Basf Aktiengesellschaft Pyrazol-4-yl-hetaroylderivate als herbizide

Also Published As

Publication number Publication date
HUP0000028A3 (en) 2003-05-28
PL201758B1 (pl) 2009-05-29
DE69734689T2 (de) 2006-06-08
CZ298174B6 (cs) 2007-07-11
CA2264756A1 (en) 1998-03-12
IL128567A0 (en) 2000-01-31
AP9901497A0 (en) 1999-06-30
CN1537846A (zh) 2004-10-20
PT927165E (pt) 2004-04-30
AU1473602A (en) 2002-03-14
EP1361216A1 (en) 2003-11-12
ES2210573T3 (es) 2004-07-01
TR199900473T2 (xx) 1999-06-21
DE69726298T2 (de) 2004-05-27
CZ298175B6 (cs) 2007-07-11
JP4149000B2 (ja) 2008-09-10
ATE254603T1 (de) 2003-12-15
ES2252586T3 (es) 2006-05-16
IS4982A (is) 1999-02-19
EP0927165B1 (en) 2003-11-19
EA002051B1 (ru) 2001-12-24
JP2001500495A (ja) 2001-01-16
HK1062171A1 (en) 2004-10-21
DK0927165T3 (da) 2004-03-15
WO1998009951A3 (en) 1998-07-09
JP2008056693A (ja) 2008-03-13
UA67727C2 (uk) 2004-07-15
SI1361216T1 (sl) 2006-02-28
IL128567A (en) 2004-03-28
SG94780A1 (en) 2003-03-18
AP1322A (en) 2004-11-04
PL331801A1 (en) 1999-08-02
SI0927165T1 (en) 2004-04-30
EP1361216B1 (en) 2005-11-16
KR20010029489A (ko) 2001-04-06
CN1183117C (zh) 2005-01-05
OA10988A (en) 2001-11-01
WO1998009951A2 (en) 1998-03-12
NZ334909A (en) 2000-06-23
BG65237B1 (bg) 2007-09-28
EE04465B1 (et) 2005-04-15
BG64793B1 (bg) 2006-04-28
AU4331797A (en) 1998-03-26
AP2003002938A0 (en) 2003-12-31
EA199900257A1 (ru) 1999-08-26
NO991072D0 (no) 1999-03-04
DE69726298D1 (de) 2003-12-24
DE69734689D1 (de) 2005-12-22
CN1232455A (zh) 1999-10-20
AU740369B2 (en) 2001-11-01
CZ71699A3 (cs) 1999-06-16
NO313287B1 (no) 2002-09-09
GEP20022799B (en) 2002-09-25
DK1361216T3 (da) 2006-01-23
BR9713192A (pt) 1999-12-21
ATE309990T1 (de) 2005-12-15
JP2008088178A (ja) 2008-04-17
SK28299A3 (en) 1999-11-08
CN1305854C (zh) 2007-03-21
EP0927165A2 (en) 1999-07-07
YU11599A (sh) 2000-03-21
PL198408B1 (pl) 2008-06-30
AU766155B2 (en) 2003-10-09
IS2030B (is) 2005-08-15
BG103305A (en) 2000-01-31
HUP0000028A2 (hu) 2000-05-28
SK285278B6 (sk) 2006-10-05
KR100563289B1 (ko) 2006-03-22
EE9900109A (et) 1999-12-15
SK284899B6 (sk) 2006-02-02

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