NO980856D0 - Piperazinderivater og fremgangsmåte for fremstilling derav - Google Patents

Piperazinderivater og fremgangsmåte for fremstilling derav

Info

Publication number
NO980856D0
NO980856D0 NO980856A NO980856A NO980856D0 NO 980856 D0 NO980856 D0 NO 980856D0 NO 980856 A NO980856 A NO 980856A NO 980856 A NO980856 A NO 980856A NO 980856 D0 NO980856 D0 NO 980856D0
Authority
NO
Norway
Prior art keywords
substituted
unsubstituted
pct
alkyl
thioalkoxy
Prior art date
Application number
NO980856A
Other languages
English (en)
Other versions
NO980856L (no
NO311616B1 (no
Inventor
Eui-Hwan Cho
Sun-Gan Chung
Sun-Hwan Lee
Ho-Seok Kwon
Jae-Eung Lee
Dong-Wook Kang
Jeong-Ho Joo
Young-Hee Lee
Original Assignee
Samjin Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019970022985A external-priority patent/KR100204319B1/ko
Priority claimed from KR1019970022984A external-priority patent/KR100204320B1/ko
Priority claimed from KR1019970023193A external-priority patent/KR100197111B1/ko
Priority claimed from KR1019970023192A external-priority patent/KR100204318B1/ko
Application filed by Samjin Pharm Co Ltd filed Critical Samjin Pharm Co Ltd
Publication of NO980856D0 publication Critical patent/NO980856D0/no
Publication of NO980856L publication Critical patent/NO980856L/no
Publication of NO311616B1 publication Critical patent/NO311616B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
NO19980856A 1996-06-29 1998-02-27 Piperazinderivater og fremgangsmåte for fremstilling derav NO311616B1 (no)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
KR19960025827 1996-06-29
KR19960025825 1996-06-29
KR19960025826 1996-06-29
KR19960040596 1996-09-18
KR1019970022985A KR100204319B1 (ko) 1996-06-29 1997-06-03 신규 피페라진 유도체 및 그 제조방법
KR1019970022984A KR100204320B1 (ko) 1996-06-29 1997-06-03 신규 피페라진 유도체 및 그 제조방법
KR1019970023193A KR100197111B1 (ko) 1996-09-18 1997-06-04 신규 피페라진 유도체 및 그 제조방법
KR1019970023192A KR100204318B1 (ko) 1996-06-29 1997-06-04 신규 피페라진 유도체 및 그 제조방법
PCT/KR1997/000128 WO1998000402A1 (en) 1996-06-29 1997-06-28 Piperazine derivatives and process for the preparation thereof

Publications (3)

Publication Number Publication Date
NO980856D0 true NO980856D0 (no) 1998-02-27
NO980856L NO980856L (no) 1998-04-27
NO311616B1 NO311616B1 (no) 2001-12-17

Family

ID=27573799

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19980856A NO311616B1 (no) 1996-06-29 1998-02-27 Piperazinderivater og fremgangsmåte for fremstilling derav

Country Status (17)

Country Link
US (1) US6028195A (no)
EP (1) EP0850222B1 (no)
JP (1) JP3032303B2 (no)
CN (1) CN1152015C (no)
AT (1) ATE241600T1 (no)
AU (1) AU713171B2 (no)
BG (1) BG102286A (no)
CA (1) CA2230960C (no)
CZ (1) CZ59398A3 (no)
DE (1) DE69722360T2 (no)
NO (1) NO311616B1 (no)
NZ (1) NZ329847A (no)
PL (1) PL325341A1 (no)
RU (1) RU2146254C1 (no)
SK (1) SK27598A3 (no)
TR (1) TR199800371T1 (no)
WO (1) WO1998000402A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1122242B1 (en) 1998-09-22 2008-01-16 Astellas Pharma Inc. Cyanophenyl derivatives
US20020065296A1 (en) 1999-01-13 2002-05-30 Bayer Corporation Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
ATE556713T1 (de) 1999-01-13 2012-05-15 Bayer Healthcare Llc Omega-carboxyarylsubstituierte-diphenyl- harnstoffe als p38-kinasehemmer
DK1690853T3 (da) 1999-01-13 2010-06-07 Bayer Healthcare Llc Omega-carboxyaryl-substituerede diphenylurinstoffer til anvendelse som raf-kinaseinhibitorer
WO2000052001A1 (en) * 1999-03-03 2000-09-08 Samjin Pharmaceutical Co., Ltd. Piperazine derivatives and process for the preparation thereof
WO2002008221A2 (en) * 2000-07-20 2002-01-31 Neurogen Corporation Capsaicin receptor ligands
DE10035927A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
DE10035928A1 (de) 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
DE10035908A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
US7183050B2 (en) 2001-04-18 2007-02-27 Krull Ulrich J Gradient resolved information platform
AU2003212882A1 (en) 2002-02-01 2003-09-02 Euro-Celtique S.A. 2 - piperazine - pyridines useful for treating pain
US7279493B2 (en) 2002-06-28 2007-10-09 Euro-Celtique S.A. Therapeutic agents useful for treating pain
MXPA04012959A (es) * 2002-06-29 2005-05-16 Zentaris Gmbh Arilcarbonilpiperacinas y heteroarilcarbonilpiperacinas y su uso para tratamiento de enfermedades de tumor benigno y maligno.
US7262194B2 (en) 2002-07-26 2007-08-28 Euro-Celtique S.A. Therapeutic agents useful for treating pain
US7157462B2 (en) 2002-09-24 2007-01-02 Euro-Celtique S.A. Therapeutic agents useful for treating pain
AU2004218260A1 (en) * 2003-01-28 2004-09-16 Aventis Pharma S.A. N-aryl heteroaromatic products, compositions containing same and use thereof
US20050130989A1 (en) * 2003-01-28 2005-06-16 Aventis Pharma S. A. N-arylheteroaromatic products compositions containing them and use thereof
JP4860474B2 (ja) 2003-05-20 2012-01-25 バイエル、ファーマシューテイカルズ、コーポレイション Pdgfrによって仲介される病気のためのジアリール尿素
EP1819698B1 (en) * 2004-11-17 2011-02-23 Rexahn Pharmaceuticals, Inc. 1-[(6-substituted alkoxyquinoxalinyl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives
US7812025B2 (en) 2005-08-12 2010-10-12 Takeda Pharmaceutical Company Limited Brain/neuronal cell-protecting agent and therapeutic agent for sleep disorder
US20090068146A1 (en) 2005-10-31 2009-03-12 Scott Wilhelm Diaryl ureas and combinations
KR20100064381A (ko) * 2007-10-10 2010-06-14 다케다 야쿠힌 고교 가부시키가이샤 아미드 화합물
US7946206B2 (en) * 2007-11-21 2011-05-24 Rocksmart, Llc Quick-release system
TWI434842B (zh) * 2008-07-14 2014-04-21 Astellas Pharma Inc Azole compounds
US20150376198A1 (en) * 2013-02-18 2015-12-31 The Scripps Research Institute Modulators of vasopressin receptors with therapeutic potential
MA44007A (fr) 2016-02-05 2018-12-19 Denali Therapeutics Inc Inhibiteurs du récepteur interagissant avec protéine kinase 1
LT3552017T (lt) 2016-12-09 2022-05-10 Denali Therapeutics Inc. Junginiai, naudotini kaip ripk1 inhibitoriai
WO2023137035A1 (en) 2022-01-12 2023-07-20 Denali Therapeutics Inc. Crystalline forms of (s)-5-benzyl-n-(5-methyl-4-oxo-2, 3,4,5- tetrahydropyrido [3,2-b] [l,4]oxazepin-3-yl)-4h-l,2,4-triazole-3-carboxamide

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016274A (en) * 1973-05-15 1977-04-05 Rhone-Poulenc S.A. Naphthyridine derivatives
US4038391A (en) * 1973-05-15 1977-07-26 Rhone-Poulenc S.A. 6-(1,8-Naphthyridin-2-yl)-5-piperazino carbonyloxy-7-oxo-6,7-dihydro-5H-pyrrolo-[3,4-b]pyrazines and related pyridines
OA04700A (fr) * 1973-05-15 1980-07-31 Rhone Poulenc Sa Nouveaux dérivés de la naphtyridine et leur procédé de préparation.
JPS63115167A (ja) * 1986-10-31 1988-05-19 Konica Corp ハロゲン化銀写真感光材料
US5391571A (en) * 1989-11-15 1995-02-21 American Home Products Corporation Cholesterol ester hydrolase inhibitors
DE4018070A1 (de) * 1990-06-06 1991-12-12 Bayer Ag Morpholinoharnstoff-derivate
ZA929008B (en) * 1991-12-13 1993-05-21 Bristol Myers Squibb Co Piperazinyl- and piperidinyl-cyclohexanols.
DE4216364A1 (de) * 1991-12-14 1993-11-25 Thomae Gmbh Dr K Neue Pyridylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5461047A (en) * 1993-06-16 1995-10-24 G. D. Searle & Co. 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
FR2722788B1 (fr) * 1994-07-20 1996-10-04 Pf Medicament Nouvelles piperazides derivees d'aryl piperazine, leurs procedes de preparation, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant
JP2978967B2 (ja) * 1995-01-11 1999-11-15 三進製藥株式會社 新規ピペラジン誘導体、その製造方法及びそれを含有する組成物

Also Published As

Publication number Publication date
DE69722360D1 (de) 2003-07-03
DE69722360T2 (de) 2003-11-27
BG102286A (en) 1999-08-31
CA2230960C (en) 2007-08-28
RU2146254C1 (ru) 2000-03-10
CA2230960A1 (en) 1998-01-08
EP0850222A1 (en) 1998-07-01
SK27598A3 (en) 1998-11-04
AU3464297A (en) 1998-01-21
PL325341A1 (en) 1998-07-20
JPH11501680A (ja) 1999-02-09
ATE241600T1 (de) 2003-06-15
CN1196724A (zh) 1998-10-21
CN1152015C (zh) 2004-06-02
CZ59398A3 (cs) 1998-07-15
NZ329847A (en) 1999-01-28
EP0850222B1 (en) 2003-05-28
AU713171B2 (en) 1999-11-25
WO1998000402A1 (en) 1998-01-08
US6028195A (en) 2000-02-22
TR199800371T1 (xx) 1998-06-22
NO980856L (no) 1998-04-27
NO311616B1 (no) 2001-12-17
JP3032303B2 (ja) 2000-04-17

Similar Documents

Publication Publication Date Title
NO980856D0 (no) Piperazinderivater og fremgangsmåte for fremstilling derav
RU95105988A (ru) Производные эфиров о-бензилоксимов, способ их получения и пестицидная композиция на их основе
TR200002671T2 (tr) Bisiklo(2.2.1)Heptanlar ve ilgili bileşikler
CA2119572A1 (en) Oxygen substituted derivatives of nucleophile-nitric oxide adducts as nitric oxide donor prodrugs
ATE33838T1 (de) Thiazolidinderivate, ihre herstellung und diese enthaltende zusammensetzungen.
CA2078759A1 (en) Novel carboxyalkyl derivatives useful as inhibitors of enkephalinase and ace
ATE135709T1 (de) Erythromycinderivate, ihr verfahren zur herstellung und ihre verwendung als arzneimitteln
MX165512B (es) Aditivo de carbamato para composicion lubricante
DE3876813D1 (de) 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.
TW368501B (en) 7-(2-aminoethyl)-benzothiazolones
NZ314003A (en) Medicaments for treating osteoporosis containing thiazolidine compounds
ES2000481A6 (es) Procecimiento de preparacion de nuevos derivados del dihidro-2,3 benzofurano
MX9202438A (es) Esteroides 3-carboxi insaturados substituidos en la posicion 17 beta, procedimiento para su preparacion y composicion farmaceutica que los contiene.
DE69202120D1 (de) Harnstoffderivate, ihre Herstellung und ihre Verwendung bei der Therapie.
ATE75737T1 (de) Indenothiazolderivate und verfahren zu ihrer herstellung.
YU47010B (sh) Derivati 1,6-naftiridina
DE69926392D1 (de) Piperazinon-derivate
BG60248B2 (en) Process for the preparation of phenoxyethylamine derivatives
ES8603414A1 (es) Un procedimiento para preparar un derivado de 1, 4-dihidropiridina disustituido en posicion 2, 6
FI875348A0 (fi) Foerfarande foer framstaellning av nya, med en sulfinylgrupp i 23-staellning omfattande steroidfoereningar.
BG100704A (en) New piperazine derivatives and methods for their preparation as well as of the compounds containing them
NO20002967L (no) Uretaner avledet fra azacycloalkaner, tio og ditio-analoger, samt anvendelse og fremstilling av 2,3 eposkysqualen- lanesterolcyclaseinhibitor
PH31474A (en) N-aminoboalkyl-substituted nitrogen-containing five membered heterocyclic compounds.
FI903511A0 (fi) Pyrrolo (2,1-b) tiazolderivat.
MY132324A (en) New piperazine derivatives and methods for the preperation thereof and compositions containing the same