NO962841L - Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler - Google Patents

Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler

Info

Publication number
NO962841L
NO962841L NO962841A NO962841A NO962841L NO 962841 L NO962841 L NO 962841L NO 962841 A NO962841 A NO 962841A NO 962841 A NO962841 A NO 962841A NO 962841 L NO962841 L NO 962841L
Authority
NO
Norway
Prior art keywords
colon cancer
hydroxy
chemopreventives
phenylazobenzoic acid
acid derivatives
Prior art date
Application number
NO962841A
Other languages
English (en)
Other versions
NO962841D0 (no
Inventor
Lorin K Johnson
Marvin H Sleisenger
Original Assignee
Salix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salix Pharmaceuticals Inc filed Critical Salix Pharmaceuticals Inc
Publication of NO962841D0 publication Critical patent/NO962841D0/no
Publication of NO962841L publication Critical patent/NO962841L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

En fremgangsmåte for coloncancer kjemoprevensjon eller kjemoterapi omfattende administrering til et individ som lider av coloncancer eller har risiko for å utvikle coloncancer en farmasøytisk sammensetning som omfatter en effektiv mengde av et 2-hydroksy-5-fenylazobenzosyre derivat eller en ester av en aktiv metabolitt eller et oksydasjonsprodukt av en aktiv metabolitt derav, eller et farmakologisk akseptabelt salt av 2-hydroksy-5-fenylazobenzosyre derivat eller en ester eller en aktiv metabolitt eller et oksydasjonsprodukt av en aktiv metabolitt derav, er beskrevet.
NO962841A 1994-01-07 1996-07-05 Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler NO962841L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/178,578 US5498608A (en) 1994-01-07 1994-01-07 Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents
PCT/US1995/000055 WO1995018622A1 (en) 1994-01-07 1995-01-06 Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents

Publications (2)

Publication Number Publication Date
NO962841D0 NO962841D0 (no) 1996-07-05
NO962841L true NO962841L (no) 1996-08-29

Family

ID=22653104

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962841A NO962841L (no) 1994-01-07 1996-07-05 Anvendelse av 2-hydroksy-5-fenylazobenzosyrederivater som colon cancer kjemopreventativer og kjemoterapeutiske midler

Country Status (18)

Country Link
US (1) US5498608A (no)
EP (1) EP0738152B1 (no)
JP (4) JPH09510958A (no)
CN (1) CN1140994A (no)
AT (1) ATE308327T1 (no)
AU (1) AU691869B2 (no)
CA (1) CA2180571C (no)
CZ (1) CZ286460B6 (no)
DE (1) DE69534564T2 (no)
DK (1) DK0738152T3 (no)
ES (1) ES2248796T3 (no)
FI (1) FI962735A (no)
HU (1) HUT74512A (no)
NO (1) NO962841L (no)
NZ (1) NZ279062A (no)
RO (1) RO116525B1 (no)
RU (1) RU2161487C2 (no)
WO (1) WO1995018622A1 (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498608A (en) * 1994-01-07 1996-03-12 Salix Pharmaceuticals Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents
US6166024A (en) 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
SE9700934D0 (sv) * 1997-03-14 1997-03-14 Astra Ab New formulation
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
DK1105141T3 (da) 1998-08-06 2004-03-08 Wolfgang Stremmel Phosphatidylcholin som et medikament med slimhindebeskyttende virkning
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
AU2001267823A1 (en) * 2000-06-29 2002-01-08 Shionogi And Co., Ltd. Compounds exhibiting x-type spla2 inhibiting effect
TWI249519B (en) 2000-08-29 2006-02-21 Nobex Corp Immunoregulatory compounds and derivatives and methods of treating diseases therewith
TWI314457B (no) * 2001-03-19 2009-09-11 Shionogi & Co
US8048924B2 (en) * 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
US7825132B2 (en) 2002-08-23 2010-11-02 Novartis Vaccines And Diagnostics, Inc. Inhibition of FGFR3 and treatment of multiple myeloma
KR20050075005A (ko) 2002-11-13 2005-07-19 카이론 코포레이션 암을 치료하는 방법 및 관련 방법
AU2005209948B2 (en) 2004-02-06 2009-09-10 Pharmatel (R&D) Pty Limited Use of aminosalicylates in diarrhoea-predominent Irritable Bowel Syndrome
BRPI0507891A (pt) 2004-02-20 2007-07-24 Chiron Corp modulação dos processos inflamatório e metastático
FR2867981B1 (fr) 2004-03-24 2008-10-31 Genevrier Sa Lab Utilisation des chondroitine mono-et disulfates en therapeutique
BRPI0511618A (pt) * 2004-05-28 2008-01-02 Salix Pharmaceuticals Inc métodos de tratar enterite induzida por radiação e de proteger contra enterite induzida por radiação, contra dano induzido por radiação a mucosa do cólon, e contra inflamação colo-retal induzida por radiação
US20080306029A1 (en) * 2004-05-28 2008-12-11 Salix Pharmaceuticals, Inc. Prevention, Treatment, and Amelioration of Radiation Induced Enteritis
EP1773767B1 (en) 2004-07-07 2016-03-09 Biocon Limited Synthesis of azo bonded immunoregulatory compounds
ES2440799T3 (es) 2005-05-13 2014-01-30 Novartis Ag Métodos para tratar cáncer resistente a los fármacos
CN103948609A (zh) 2005-08-24 2014-07-30 萨利克斯药品公司 巴柳氮制剂及其生产和应用
US8921344B2 (en) * 2006-11-03 2014-12-30 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
US7452872B2 (en) * 2005-08-24 2008-11-18 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
RU2354384C1 (ru) * 2007-12-28 2009-05-10 Михаил Владимирович Кутушов Применение органических красителей в качестве средства для лечения онкологических заболеваний
WO2010030781A2 (en) * 2008-09-10 2010-03-18 Numed International, Inc. Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancer
EP2298321A1 (en) 2009-08-26 2011-03-23 Nordic Pharma Novel pharmaceutical compositions for treating IBD
JP2013525440A (ja) 2010-04-26 2013-06-20 サリックス ファーマシューティカルズ リミテッド 男性の治療のための２−ヒドロキシ−５−フェニルアゾ安息香酸誘導体の製剤および使用
CN116173220A (zh) * 2022-03-02 2023-05-30 上海赛金生物医药有限公司 Ctla-4抑制剂和非类固醇抗炎药的抗癌联合治疗方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4412992A (en) * 1980-07-21 1983-11-01 Biorex Laboratories Limited 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith
GB2080796B (en) * 1980-07-21 1983-10-12 Biorex Laboratories Ltd 2-hydroxy-5-phenylazobenzoic acid derivatives
NZ212419A (en) * 1984-06-25 1988-08-30 Mucan Diagnostics Pty Ltd In vitro diagnostic test for detecting cancer cells producing mucin antigens
US5162202A (en) * 1989-12-12 1992-11-10 Shamsuddin Abulkalam M Rectal mucus test and kit for detecting cancerous and precancerous conditions
US5498608A (en) * 1994-01-07 1996-03-12 Salix Pharmaceuticals Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents

Also Published As

Publication number Publication date
HUT74512A (en) 1997-01-28
CA2180571C (en) 2001-03-20
CA2180571A1 (en) 1995-07-13
DK0738152T3 (da) 2006-01-30
US5498608A (en) 1996-03-12
HU9601846D0 (en) 1996-09-30
JPH09510958A (ja) 1997-11-04
EP0738152A4 (en) 2000-12-13
JP4601466B2 (ja) 2010-12-22
FI962735A0 (fi) 1996-07-03
NZ279062A (en) 1999-11-29
JP2005320326A (ja) 2005-11-17
JP2010235629A (ja) 2010-10-21
RU2161487C2 (ru) 2001-01-10
JP2006096738A (ja) 2006-04-13
ATE308327T1 (de) 2005-11-15
FI962735A (fi) 1996-08-26
AU1557595A (en) 1995-08-01
EP0738152B1 (en) 2005-11-02
CZ196796A3 (en) 1996-12-11
CZ286460B6 (en) 2000-04-12
EP0738152A1 (en) 1996-10-23
ES2248796T3 (es) 2006-03-16
CN1140994A (zh) 1997-01-22
WO1995018622A1 (en) 1995-07-13
DE69534564T2 (de) 2006-07-27
RO116525B1 (ro) 2001-03-30
NO962841D0 (no) 1996-07-05
AU691869B2 (en) 1998-05-28
DE69534564D1 (de) 2005-12-08

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