FI962735A - 2-hydroksi-5-fenylatsobensoehapon johdannaisten käyttö paksusuolen syövän kemialliseen ehkäisyyn ja kemoterapeuttisena aineena - Google Patents

2-hydroksi-5-fenylatsobensoehapon johdannaisten käyttö paksusuolen syövän kemialliseen ehkäisyyn ja kemoterapeuttisena aineena Download PDF

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Publication number
FI962735A
FI962735A FI962735A FI962735A FI962735A FI 962735 A FI962735 A FI 962735A FI 962735 A FI962735 A FI 962735A FI 962735 A FI962735 A FI 962735A FI 962735 A FI962735 A FI 962735A
Authority
FI
Finland
Prior art keywords
colon cancer
hydroxy
preventive
phenylazobenzoic acid
acid derivatives
Prior art date
Application number
FI962735A
Other languages
English (en)
Swedish (sv)
Other versions
FI962735A0 (fi
Inventor
Lorin K Johnson
Marvin H Sleisenger
Original Assignee
Salix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salix Pharmaceuticals Inc filed Critical Salix Pharmaceuticals Inc
Publication of FI962735A0 publication Critical patent/FI962735A0/fi
Publication of FI962735A publication Critical patent/FI962735A/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI962735A 1994-01-07 1996-07-03 2-hydroksi-5-fenylatsobensoehapon johdannaisten käyttö paksusuolen syövän kemialliseen ehkäisyyn ja kemoterapeuttisena aineena FI962735A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/178,578 US5498608A (en) 1994-01-07 1994-01-07 Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents
PCT/US1995/000055 WO1995018622A1 (en) 1994-01-07 1995-01-06 Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents

Publications (2)

Publication Number Publication Date
FI962735A0 FI962735A0 (fi) 1996-07-03
FI962735A true FI962735A (fi) 1996-08-26

Family

ID=22653104

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962735A FI962735A (fi) 1994-01-07 1996-07-03 2-hydroksi-5-fenylatsobensoehapon johdannaisten käyttö paksusuolen syövän kemialliseen ehkäisyyn ja kemoterapeuttisena aineena

Country Status (18)

Country Link
US (1) US5498608A (fi)
EP (1) EP0738152B1 (fi)
JP (4) JPH09510958A (fi)
CN (1) CN1140994A (fi)
AT (1) ATE308327T1 (fi)
AU (1) AU691869B2 (fi)
CA (1) CA2180571C (fi)
CZ (1) CZ286460B6 (fi)
DE (1) DE69534564T2 (fi)
DK (1) DK0738152T3 (fi)
ES (1) ES2248796T3 (fi)
FI (1) FI962735A (fi)
HU (1) HUT74512A (fi)
NO (1) NO962841L (fi)
NZ (1) NZ279062A (fi)
RO (1) RO116525B1 (fi)
RU (1) RU2161487C2 (fi)
WO (1) WO1995018622A1 (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498608A (en) * 1994-01-07 1996-03-12 Salix Pharmaceuticals Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents
US6166024A (en) * 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
SE9700934D0 (sv) * 1997-03-14 1997-03-14 Astra Ab New formulation
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
ES2211184T3 (es) 1998-08-06 2004-07-01 Wolfgang Stremmel Fosfatidilcolina como medicamento con efecto protector de mucosas.
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
AU2001267823A1 (en) * 2000-06-29 2002-01-08 Shionogi And Co., Ltd. Compounds exhibiting x-type spla2 inhibiting effect
CA2420576C (en) 2000-08-29 2005-06-14 Nobex Corporation Immunoregulatory compounds, derivatives thereof and their use
TWI314457B (fi) * 2001-03-19 2009-09-11 Shionogi & Co
US8048924B2 (en) * 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
US7825132B2 (en) 2002-08-23 2010-11-02 Novartis Vaccines And Diagnostics, Inc. Inhibition of FGFR3 and treatment of multiple myeloma
EP1565187A4 (en) 2002-11-13 2010-02-17 Novartis Vaccines & Diagnostic CANCER TREATMENT METHODS AND RELATED METHODS
ATE554752T1 (de) 2004-02-06 2012-05-15 Pharmatel R & D Pty Ltd As Trustee For The Pharmatel R & D Trust Verwendung von aminosalicylaten beim reizdarmsyndrom mit durchfall als vorherrschendem symptom
CA2556872C (en) 2004-02-20 2015-05-12 Chiron Corporation Modulation of inflammatory and metastatic processes
FR2867981B1 (fr) 2004-03-24 2008-10-31 Genevrier Sa Lab Utilisation des chondroitine mono-et disulfates en therapeutique
CN1988897B (zh) * 2004-05-28 2011-06-29 萨利克斯药物有限公司 巴柳氮在制备治疗因放射所引起的肠炎的药物的应用
US20080306029A1 (en) * 2004-05-28 2008-12-11 Salix Pharmaceuticals, Inc. Prevention, Treatment, and Amelioration of Radiation Induced Enteritis
PL1773767T3 (pl) 2004-07-07 2016-07-29 Biocon Ltd Synteza azowo związanych związków immunoregulacyjnych
MX2007014206A (es) 2005-05-13 2008-02-07 Novartis Ag Metodos para tratar cancer resistente a los farmacos.
US7452872B2 (en) * 2005-08-24 2008-11-18 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
US8921344B2 (en) * 2006-11-03 2014-12-30 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
NZ565974A (en) * 2005-08-24 2012-07-27 Salix Pharmaceuticals Ltd Balsalazide formulations and manufacture and use thereof
RU2354384C1 (ru) * 2007-12-28 2009-05-10 Михаил Владимирович Кутушов Применение органических красителей в качестве средства для лечения онкологических заболеваний
WO2010030781A2 (en) * 2008-09-10 2010-03-18 Numed International, Inc. Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancer
EP2298321A1 (en) 2009-08-26 2011-03-23 Nordic Pharma Novel pharmaceutical compositions for treating IBD
BR122014009845A2 (pt) 2010-04-26 2015-12-29 Salix Pharmaceuticals Ltd usos de balsalazida para preparação de composição farmacêutica para tratamento de distúrbio gastrointestinal e induzir remissão clínica de colite ulcerativa em indivíduos do sexo masculino, bem como para diminuir o escore de mmdai e cicatrização da mucosa em indivíduos do sexo masculino com colite ulcerativa

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2080796B (en) * 1980-07-21 1983-10-12 Biorex Laboratories Ltd 2-hydroxy-5-phenylazobenzoic acid derivatives
US4412992A (en) * 1980-07-21 1983-11-01 Biorex Laboratories Limited 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith
NZ212419A (en) * 1984-06-25 1988-08-30 Mucan Diagnostics Pty Ltd In vitro diagnostic test for detecting cancer cells producing mucin antigens
US5162202A (en) * 1989-12-12 1992-11-10 Shamsuddin Abulkalam M Rectal mucus test and kit for detecting cancerous and precancerous conditions
US5498608A (en) * 1994-01-07 1996-03-12 Salix Pharmaceuticals Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents

Also Published As

Publication number Publication date
JP4601466B2 (ja) 2010-12-22
CN1140994A (zh) 1997-01-22
DE69534564T2 (de) 2006-07-27
CZ286460B6 (en) 2000-04-12
FI962735A0 (fi) 1996-07-03
AU691869B2 (en) 1998-05-28
ES2248796T3 (es) 2006-03-16
CA2180571A1 (en) 1995-07-13
NO962841L (no) 1996-08-29
HU9601846D0 (en) 1996-09-30
CZ196796A3 (en) 1996-12-11
EP0738152A1 (en) 1996-10-23
WO1995018622A1 (en) 1995-07-13
US5498608A (en) 1996-03-12
JP2010235629A (ja) 2010-10-21
DE69534564D1 (de) 2005-12-08
AU1557595A (en) 1995-08-01
RO116525B1 (ro) 2001-03-30
RU2161487C2 (ru) 2001-01-10
EP0738152B1 (en) 2005-11-02
JPH09510958A (ja) 1997-11-04
EP0738152A4 (en) 2000-12-13
JP2005320326A (ja) 2005-11-17
NZ279062A (en) 1999-11-29
CA2180571C (en) 2001-03-20
JP2006096738A (ja) 2006-04-13
ATE308327T1 (de) 2005-11-15
HUT74512A (en) 1997-01-28
DK0738152T3 (da) 2006-01-30
NO962841D0 (no) 1996-07-05

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