NO962261D0 - Hirudin-konjugater av hirudin og lipofile forbindelser - Google Patents

Hirudin-konjugater av hirudin og lipofile forbindelser

Info

Publication number
NO962261D0
NO962261D0 NO962261A NO962261A NO962261D0 NO 962261 D0 NO962261 D0 NO 962261D0 NO 962261 A NO962261 A NO 962261A NO 962261 A NO962261 A NO 962261A NO 962261 D0 NO962261 D0 NO 962261D0
Authority
NO
Norway
Prior art keywords
hirudin
pct
lipophilic compounds
conjugates
date
Prior art date
Application number
NO962261A
Other languages
English (en)
Norwegian (no)
Other versions
NO962261L (no
Inventor
Jurgen Schweden
Peter Eckes
Wilfried Hornberger
Thomas Subkowski
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO962261D0 publication Critical patent/NO962261D0/no
Publication of NO962261L publication Critical patent/NO962261L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/545Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Fats And Perfumes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)
  • Ink Jet (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Silicon Polymers (AREA)
NO962261A 1993-12-02 1996-05-31 Hirudin-konjugater av hirudin og lipofile forbindelser NO962261L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4341115 1993-12-02
PCT/EP1994/003901 WO1995015183A1 (de) 1993-12-02 1994-11-25 Hirudin-konjugate aus hirudin und lipophilen verbindungen

Publications (2)

Publication Number Publication Date
NO962261D0 true NO962261D0 (no) 1996-05-31
NO962261L NO962261L (no) 1996-05-31

Family

ID=6504029

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962261A NO962261L (no) 1993-12-02 1996-05-31 Hirudin-konjugater av hirudin og lipofile forbindelser

Country Status (25)

Country Link
US (1) US5919762A (sk)
EP (1) EP0730473B1 (sk)
JP (1) JPH09505810A (sk)
CN (1) CN1142776A (sk)
AT (1) ATE204763T1 (sk)
AU (1) AU679811B2 (sk)
BR (1) BR9408195A (sk)
CA (1) CA2176967A1 (sk)
CZ (1) CZ157096A3 (sk)
DE (2) DE4437502A1 (sk)
DK (1) DK0730473T3 (sk)
ES (1) ES2163487T3 (sk)
FI (1) FI962299A0 (sk)
GR (1) GR3036938T3 (sk)
HR (1) HRP940968A2 (sk)
HU (1) HUT74390A (sk)
IL (1) IL111811A0 (sk)
NO (1) NO962261L (sk)
NZ (1) NZ276410A (sk)
PL (1) PL314797A1 (sk)
PT (1) PT730473E (sk)
SG (1) SG49156A1 (sk)
SK (1) SK67596A3 (sk)
WO (1) WO1995015183A1 (sk)
ZA (1) ZA949562B (sk)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4437604A1 (de) * 1994-10-21 1996-04-25 Basf Ag Konjugate aus einem Poly- oder Oligopeptid und einer niedermolekularen lipophilen Verbindung
US5726168A (en) * 1995-10-12 1998-03-10 Eli Lilly And Company Lipophilic benzothiophenes
DE19915862A1 (de) * 1999-04-08 2000-10-12 Max Planck Gesellschaft Verwendung von molekulargewichtserweitertem Hirudin als Antikoagulans bei der extrakorporalen Nierenersatztherapie
WO2003035167A2 (en) * 2001-10-24 2003-05-01 Power Paper Ltd Device and method for controlled delivery of active substance into the skin
US7438925B2 (en) * 2002-08-26 2008-10-21 Biovention Holdings Ltd. Drug eluting coatings for medical implants
BR102017005783A2 (pt) * 2017-03-21 2018-10-02 Fund Butantan processo de obtenção de esculptina e seus fragmentos, esculptina recombinante e seus usos
KR102366360B1 (ko) * 2021-06-29 2022-02-23 (주)네오팜 신규한 유사 세라마이드 화합물 및 이를 포함하는 피부 외용제 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0077529B1 (de) * 1981-10-16 1985-07-17 Sanol Schwarz GmbH Arzneimittelformulierung
DE3445532A1 (de) * 1984-12-13 1986-06-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Hirudin-pa, desulfatohirudine-pa, verfahren zur herstellung und pharmazeutische mittel, die diese wirkstoffe enthalten
US4939174A (en) * 1988-02-26 1990-07-03 Shashoua Victor E Appetite suppression with dopamine-fatty acid conjugates
DE3819079A1 (de) * 1988-06-04 1989-12-07 Hoechst Ag Hirudin-derivate mit verzoegerter wirkung
ES2055907T3 (es) * 1989-03-07 1994-09-01 Genentech Inc Conjugados covalentes de lipidos y oligonucleotidos.
CA2067224C (en) * 1989-12-01 2001-02-13 Manfred Kurfuerst Hirudin/polyalkylene glycol conjugates
DE4014260A1 (de) * 1989-12-01 1991-06-06 Basf Ag Hirudinpolyalkylenglykolkonjugate
WO1991009837A1 (en) * 1989-12-22 1991-07-11 Commonwealth Scientific And Industrial Research Organisation Amino acids, peptides or derivatives thereof coupled to fats
JPH05505941A (ja) * 1990-03-29 1993-09-02 ギリード サイエンシズ インコーポレーテッド オリゴヌクレオチド―輸送剤ジスルフィド結合体
US5256641A (en) * 1990-11-01 1993-10-26 State Of Oregon Covalent polar lipid-peptide conjugates for immunological targeting
WO1992019233A2 (en) * 1991-04-29 1992-11-12 Control Delivery Systems, Inc. Sustained release composition and methods of use thereof
AU1664892A (en) * 1991-05-02 1992-12-21 Pierre Baudet N-phenyl-cinnamamides providing protection from the harmful effects of ultraviolet light
US5359030A (en) * 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same

Also Published As

Publication number Publication date
BR9408195A (pt) 1997-08-26
HUT74390A (en) 1996-12-30
SG49156A1 (en) 1998-05-18
EP0730473A1 (de) 1996-09-11
US5919762A (en) 1999-07-06
NO962261L (no) 1996-05-31
AU1067095A (en) 1995-06-19
PL314797A1 (en) 1996-09-30
HU9601471D0 (en) 1996-07-29
IL111811A0 (en) 1995-01-24
FI962299A (fi) 1996-05-31
WO1995015183A1 (de) 1995-06-08
DE4437502A1 (de) 1995-06-08
NZ276410A (en) 1997-03-24
FI962299A0 (fi) 1996-05-31
SK67596A3 (en) 1996-12-04
CN1142776A (zh) 1997-02-12
DE59409847D1 (de) 2001-10-04
DK0730473T3 (da) 2001-10-08
JPH09505810A (ja) 1997-06-10
CA2176967A1 (en) 1995-06-08
HRP940968A2 (en) 1997-08-31
ATE204763T1 (de) 2001-09-15
GR3036938T3 (en) 2002-01-31
AU679811B2 (en) 1997-07-10
EP0730473B1 (de) 2001-08-29
ZA949562B (en) 1996-06-03
CZ157096A3 (en) 1996-09-11
PT730473E (pt) 2002-02-28
ES2163487T3 (es) 2002-02-01

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