NO884127L - Nye dicarboxylsyre-bis(3,5-dicarbamoyl-2,4,6-trijodanilider), fremgangsmaate for fremstilling av disse, og roentgenkontrastmidler inneholdende disse. - Google Patents
Nye dicarboxylsyre-bis(3,5-dicarbamoyl-2,4,6-trijodanilider), fremgangsmaate for fremstilling av disse, og roentgenkontrastmidler inneholdende disse.Info
- Publication number
- NO884127L NO884127L NO88884127A NO884127A NO884127L NO 884127 L NO884127 L NO 884127L NO 88884127 A NO88884127 A NO 88884127A NO 884127 A NO884127 A NO 884127A NO 884127 L NO884127 L NO 884127L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl radical
- chain
- dicarboxylic acid
- branched
- hydrogen
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 229940039231 contrast media Drugs 0.000 abstract 2
- 239000002872 contrast media Substances 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 238000009877 rendering Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Paints Or Removers (AREA)
- Polyurethanes Or Polyureas (AREA)
- Polyesters Or Polycarbonates (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polyamides (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873731542 DE3731542A1 (de) | 1987-09-17 | 1987-09-17 | Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO884127D0 NO884127D0 (no) | 1988-09-16 |
| NO884127L true NO884127L (no) | 1989-03-20 |
| NO175857B NO175857B (no) | 1994-09-12 |
| NO175857C NO175857C (no) | 1994-12-21 |
Family
ID=6336386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO884127A NO175857C (no) | 1987-09-17 | 1988-09-16 | Nye dicarboxylsyre-bis(3,5-dicarbamoyl-2,4,6-trijodanilider), og röntgenkontrastmidler inneholdende disse |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5073362A (no) |
| EP (1) | EP0308364B1 (no) |
| JP (1) | JP2569144B2 (no) |
| KR (1) | KR0139061B1 (no) |
| AT (1) | ATE97126T1 (no) |
| AU (1) | AU616203B2 (no) |
| CA (1) | CA1333911C (no) |
| DE (2) | DE3731542A1 (no) |
| DK (1) | DK514788A (no) |
| ES (1) | ES2059557T3 (no) |
| FI (1) | FI93208C (no) |
| IE (1) | IE62460B1 (no) |
| NO (1) | NO175857C (no) |
| PT (1) | PT88537B (no) |
| ZA (1) | ZA886939B (no) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3739098A1 (de) * | 1987-11-16 | 1989-05-24 | Schering Ag | Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
| JPH0625094B2 (ja) * | 1988-03-01 | 1994-04-06 | マリンクロット，インコーポレイテッド | 非イオン性ｘ線コントラスト剤、組成物及び方法 |
| IL94718A (en) * | 1989-07-05 | 1994-10-21 | Schering Ag | Non-ionic carboxamide contrast agent and method of preparation |
| US5191120A (en) * | 1989-12-13 | 1993-03-02 | Mallinckrodt Medical, Inc. | Process for preparing nonionic X-ray contrast agents |
| US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
| IT1245853B (it) * | 1990-11-16 | 1994-10-25 | Bracco Spa | 1,3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2,4,6-triiodo-benzoil-amino)-idrossi- o idrossi-alchil- propani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono |
| FR2673180B1 (fr) * | 1991-02-25 | 1994-03-04 | Guerbet Sa | Nouveaux composes non ioniques poly-iodes, procede de preparation, produit de contraste les contenant. |
| ES2037605B1 (es) * | 1991-11-18 | 1994-02-01 | Invest Justesa Imagen S A Cent | Metodo para preparar nuevos agentes yodados no ionicos de constraste a los rayos x. |
| FR2695125B1 (fr) * | 1992-08-25 | 1994-12-23 | Guerbet Sa | Nouveaux composés poly-iodés, procédé de préparation, produit de contraste les contenant. |
| WO1994022810A1 (es) * | 1993-04-01 | 1994-10-13 | Centro Investigacion Justesa Imagen, S.A. | Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen |
| US5611342A (en) * | 1994-02-15 | 1997-03-18 | Molecular Biosystems, Inc. | Method of computer tomography imaging the gastrointestinal tract and surrounding upper abdominal tissues and organs using an orally administered low density contrast medium |
| WO1995026331A1 (es) * | 1994-03-25 | 1995-10-05 | Centro Investigacion Justesa Imagen, S.A. | Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones farmaceuticas que los contienen |
| SE520688C2 (sv) | 2000-04-11 | 2003-08-12 | Bone Support Ab | Ett injicerbart ersättningsmaterial för benmineral |
| SE517168C2 (sv) | 2000-07-17 | 2002-04-23 | Bone Support Ab | En komposition för ett injicerbart ersättningsmaterial för benmineral |
| EP1465678B1 (en) | 2001-12-20 | 2007-06-27 | Bone Support AB | A new bone mineral substitute |
| SE522098C2 (sv) | 2001-12-20 | 2004-01-13 | Bone Support Ab | Ett nytt benmineralsubstitut |
| KR100442293B1 (ko) | 2001-12-27 | 2004-07-30 | 엘지.필립스 엘시디 주식회사 | 패턴 형성방법 |
| SE0300620D0 (sv) | 2003-03-05 | 2003-03-05 | Bone Support Ab | A new bone substitute composition |
| SE0302983D0 (sv) | 2003-11-11 | 2003-11-11 | Bone Support Ab | Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed |
| SE527528C2 (sv) | 2004-06-22 | 2006-04-04 | Bone Support Ab | Anordning för framställning av härdbar massa samt användning av anordningen |
| JP2008520734A (ja) * | 2004-11-19 | 2008-06-19 | バイオクァンタ コーポレイション | Ｐｆ４ファーマコフォア及びそれらの使用 |
| RU2446160C2 (ru) * | 2006-09-13 | 2012-03-27 | Санофи-Авентис | Тартратные производные для применения в качестве ингибиторов фактора свертывания крови ixa |
| US9180137B2 (en) | 2010-02-09 | 2015-11-10 | Bone Support Ab | Preparation of bone cement compositions |
| KR101012646B1 (ko) * | 2010-04-01 | 2011-02-09 | 대우조선해양 주식회사 | 공기 공동 선박 |
| WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
| PT2958603T (pt) | 2013-02-20 | 2018-06-06 | Bone Support Ab | Endurecimento melhorado de substituto ósseo endurecível |
| US10610366B2 (en) | 2015-01-29 | 2020-04-07 | Theracell, Inc. | Demineralized bone fiber composition for use in minimally invasive surgery |
| US10639157B2 (en) | 2017-03-14 | 2020-05-05 | Theracell, Inc. | Demineralized bone fiber composition for use in minimally invasive surgery |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2628517C2 (de) * | 1976-06-23 | 1985-02-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
| CH626873A5 (no) * | 1977-03-28 | 1981-12-15 | Bracco Ind Chimica Spa | |
| DE2909439A1 (de) * | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
| DK273280A (da) * | 1979-06-28 | 1980-12-29 | Schering Ag | Trijoderede 5-aminoisophthalsyrederivater |
| IT1207226B (it) * | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
| US4341756A (en) * | 1980-01-31 | 1982-07-27 | The Regents Of The University Of California | Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media |
| NO161560C (no) * | 1980-04-17 | 1989-09-06 | Univ California | Symmetriske trijodisoftaldiamid-derivater og roentgenkontrastmidler inneholdende disse. |
| DE3038853A1 (de) * | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
| JPS59104352A (ja) * | 1982-11-08 | 1984-06-16 | ニユエガ−ド・アンド・コンパニ−・アクシエ・セルカペト | Ｘ線造影剤 |
| DE3739098A1 (de) * | 1987-11-16 | 1989-05-24 | Schering Ag | Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel |
-
1987
- 1987-09-17 DE DE19873731542 patent/DE3731542A1/de not_active Withdrawn
-
1988
- 1988-09-14 JP JP63228903A patent/JP2569144B2/ja not_active Expired - Lifetime
- 1988-09-14 CA CA000577366A patent/CA1333911C/en not_active Expired - Fee Related
- 1988-09-15 DK DK514788A patent/DK514788A/da not_active Application Discontinuation
- 1988-09-15 EP EP88730215A patent/EP0308364B1/de not_active Expired - Lifetime
- 1988-09-15 AT AT88730215T patent/ATE97126T1/de not_active IP Right Cessation
- 1988-09-15 ES ES88730215T patent/ES2059557T3/es not_active Expired - Lifetime
- 1988-09-15 DE DE88730215T patent/DE3885557D1/de not_active Expired - Lifetime
- 1988-09-16 FI FI884271A patent/FI93208C/fi not_active IP Right Cessation
- 1988-09-16 KR KR1019880011967A patent/KR0139061B1/ko not_active IP Right Cessation
- 1988-09-16 IE IE280888A patent/IE62460B1/en not_active IP Right Cessation
- 1988-09-16 NO NO884127A patent/NO175857C/no unknown
- 1988-09-16 PT PT88537A patent/PT88537B/pt not_active IP Right Cessation
- 1988-09-16 AU AU22251/88A patent/AU616203B2/en not_active Ceased
- 1988-09-16 ZA ZA886939A patent/ZA886939B/xx unknown
-
1990
- 1990-07-16 US US07/554,948 patent/US5073362A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE882808L (en) | 1989-03-17 |
| ES2059557T3 (es) | 1994-11-16 |
| EP0308364B1 (de) | 1993-11-10 |
| US5073362A (en) | 1991-12-17 |
| KR0139061B1 (ko) | 1998-05-01 |
| AU616203B2 (en) | 1991-10-24 |
| DE3885557D1 (de) | 1993-12-16 |
| DE3731542A1 (de) | 1989-03-30 |
| CA1333911C (en) | 1995-01-10 |
| FI884271A (fi) | 1989-03-18 |
| ZA886939B (en) | 1989-06-28 |
| JPH0196160A (ja) | 1989-04-14 |
| DK514788D0 (da) | 1988-09-15 |
| PT88537B (pt) | 1992-11-30 |
| JP2569144B2 (ja) | 1997-01-08 |
| AU2225188A (en) | 1989-04-13 |
| EP0308364A3 (de) | 1991-01-30 |
| NO175857C (no) | 1994-12-21 |
| IE62460B1 (en) | 1995-02-08 |
| ATE97126T1 (de) | 1993-11-15 |
| EP0308364A2 (de) | 1989-03-22 |
| DK514788A (da) | 1989-03-18 |
| FI884271A0 (fi) | 1988-09-16 |
| NO175857B (no) | 1994-09-12 |
| PT88537A (pt) | 1988-10-01 |
| FI93208B (fi) | 1994-11-30 |
| FI93208C (fi) | 1995-03-10 |
| KR890005034A (ko) | 1989-05-11 |
| NO884127D0 (no) | 1988-09-16 |
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