NO881940L - 4-aminokinolin-derivater og deres anvendelse som legemidler. - Google Patents

4-aminokinolin-derivater og deres anvendelse som legemidler.

Info

Publication number
NO881940L
NO881940L NO881940A NO881940A NO881940L NO 881940 L NO881940 L NO 881940L NO 881940 A NO881940 A NO 881940A NO 881940 A NO881940 A NO 881940A NO 881940 L NO881940 L NO 881940L
Authority
NO
Norway
Prior art keywords
6alkyl
phenyl
aminoqinoline
pharmaceuticals
derivatives
Prior art date
Application number
NO881940A
Other languages
English (en)
Other versions
NO172388B (no
NO172388C (no
NO881940D0 (no
Inventor
Thomas Henry Brown
Robert John Ife
Colin Andrew Leach
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of NO881940L publication Critical patent/NO881940L/no
Publication of NO881940D0 publication Critical patent/NO881940D0/no
Publication of NO172388B publication Critical patent/NO172388B/no
Publication of NO172388C publication Critical patent/NO172388C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • C07D215/44Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO881940A 1986-09-05 1988-05-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive 4-aminokinolin-derivater NO172388C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868621425A GB8621425D0 (en) 1986-09-05 1986-09-05 Compounds
PCT/GB1987/000624 WO1988001621A1 (en) 1986-09-05 1987-09-04 4-aminoquinoline derivatives and their use as medicaments

Publications (4)

Publication Number Publication Date
NO881940L true NO881940L (no) 1988-05-04
NO881940D0 NO881940D0 (no) 1988-05-04
NO172388B NO172388B (no) 1993-04-05
NO172388C NO172388C (no) 1993-07-14

Family

ID=10603729

Family Applications (1)

Application Number Title Priority Date Filing Date
NO881940A NO172388C (no) 1986-09-05 1988-05-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive 4-aminokinolin-derivater

Country Status (28)

Country Link
US (2) US4806549A (no)
EP (1) EP0259174B1 (no)
JP (1) JPH07602B2 (no)
KR (1) KR950013850B1 (no)
CN (1) CN1019802B (no)
AT (1) ATE73776T1 (no)
AU (1) AU598299B2 (no)
CA (1) CA1308106C (no)
CZ (1) CZ398291A3 (no)
DE (1) DE3777505D1 (no)
DK (1) DK159308C (no)
EG (1) EG18408A (no)
ES (1) ES2033316T3 (no)
FI (1) FI88919C (no)
GB (1) GB8621425D0 (no)
GR (1) GR3004692T3 (no)
HU (1) HU199804B (no)
IE (1) IE61104B1 (no)
IL (1) IL83691A (no)
MX (1) MX9203550A (no)
MY (1) MY102689A (no)
NO (1) NO172388C (no)
NZ (1) NZ221663A (no)
PH (1) PH23695A (no)
PT (1) PT85651B (no)
WO (1) WO1988001621A1 (no)
ZA (1) ZA876581B (no)
ZW (1) ZW16787A1 (no)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5049567A (en) * 1988-02-25 1991-09-17 Smithkline Beckman Intercredit B.V. Substituted 4-aminoquinazoline derivatives and method of use
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2632305B1 (fr) * 1988-06-06 1992-05-15 Sanofi Sa Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
WO1991014677A1 (fr) * 1990-03-28 1991-10-03 Otsuka Pharmaceutical Co., Ltd. Derive de quinoline, medicament anti-ulcereux contenant ce derive et production de ce derive
GB9126438D0 (en) * 1991-12-12 1992-02-12 Smithkline Beecham Intercredit New quinoline derivatives
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
SE9302005D0 (sv) 1993-06-11 1993-06-11 Ab Astra New active compounds
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
IN188411B (no) * 1997-03-27 2002-09-21 Yuhan Corp
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
GB2355657B (en) * 1999-10-27 2004-07-28 Phytopharm Plc Inhibitors Of Gastric Acid Secretion
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
AU2002342917A1 (en) * 2001-11-19 2003-06-10 Altana Pharma Ag Reversible proton pump inhibitors for the treatment of airway disorders
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
US20050222193A1 (en) * 2002-05-07 2005-10-06 Guido Hanauer Novel combination for the treatment of airway disorders
JP4634144B2 (ja) * 2002-08-01 2011-02-16 ニコックス エスエー ニトロソ化プロトンポンプ阻害剤、組成物および使用方法
ME00524B (me) 2003-03-10 2011-10-10 Astrazeneca Ab Novi postupak za dobijanje roflumilasta
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2-a]吡啶衍生物
SE0400284D0 (sv) * 2004-02-10 2004-02-10 Astrazeneca Ab Novel compounds
WO2006097456A1 (en) * 2005-03-16 2006-09-21 Nycomed Gmbh Taste masked dosage form containing roflumilast
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
EP2046334B1 (en) 2006-07-25 2014-05-21 Vecta Ltd. Compositions and meth0ds for inhibiting gastric acide secretion using derivatives of small dicarboxylic acids in combination with ppi
US20080103169A1 (en) 2006-10-27 2008-05-01 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
TW200829555A (en) * 2006-11-10 2008-07-16 Astrazeneca Ab Chemical compounds
CL2008000191A1 (es) * 2007-01-25 2008-08-22 Astrazeneca Ab Compuestos derivados de 4-amino-cinnotina-3-carboxamida; inhibidores de csf-1r quinasa; su proceso de preparacion; y su uso para tratar el cancer.
AU2009215514B9 (en) 2008-02-20 2014-01-30 The Curators Of The University Of Missouri Composition comprising a combination of omeprazole and lansoprazole, and a buffering agent, and methods of using same
TW200948803A (en) * 2008-05-07 2009-12-01 Astrazeneca Ab Chemical compounds
US8247280B2 (en) 2009-10-20 2012-08-21 Taiwan Semiconductor Manufacturing Company, Ltd. Integration of low and high voltage CMOS devices
US20210177827A1 (en) * 2017-10-25 2021-06-17 Children`S Medical Center Corporation Papd5 inhibitors and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343804A (en) * 1979-03-26 1982-08-10 A. H. Robins Company, Inc. 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
PH22302A (en) * 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
EP0193329A3 (en) * 1985-02-22 1987-08-19 Beecham Group Plc Pyrazolopyridines, their preparation and pharmaceutical compositions containing them
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Also Published As

Publication number Publication date
IE61104B1 (en) 1994-10-05
NO172388B (no) 1993-04-05
PT85651A (en) 1987-10-01
FI882089A0 (fi) 1988-05-04
HUT47913A (en) 1989-04-28
WO1988001621A1 (en) 1988-03-10
CN1019802B (zh) 1992-12-30
JPH01500664A (ja) 1989-03-09
EG18408A (en) 1993-02-28
FI88919C (fi) 1993-07-26
KR880701711A (ko) 1988-11-04
US4806549A (en) 1989-02-21
NZ221663A (en) 1989-08-29
US4806550A (en) 1989-02-21
IL83691A (en) 1993-08-18
KR950013850B1 (ko) 1995-11-17
JPH07602B2 (ja) 1995-01-11
IE872370L (en) 1988-03-05
NO172388C (no) 1993-07-14
ZA876581B (en) 1989-04-26
DK159308B (da) 1990-10-01
CA1308106C (en) 1992-09-29
HU199804B (en) 1990-03-28
CN87106163A (zh) 1988-03-16
EP0259174A1 (en) 1988-03-09
DK245888A (da) 1988-05-05
CZ398291A3 (en) 1994-02-16
FI88919B (fi) 1993-04-15
DK159308C (da) 1991-03-11
GB8621425D0 (en) 1986-10-15
AU598299B2 (en) 1990-06-21
DK245888D0 (da) 1988-05-05
ZW16787A1 (en) 1988-05-25
AU7874187A (en) 1988-03-24
GR3004692T3 (no) 1993-04-28
ATE73776T1 (de) 1992-04-15
FI882089A (fi) 1988-05-04
MY102689A (en) 1992-09-30
NO881940D0 (no) 1988-05-04
EP0259174B1 (en) 1992-03-18
ES2033316T3 (es) 1993-03-16
MX9203550A (es) 1992-09-01
DE3777505D1 (de) 1992-04-23
PT85651B (pt) 1990-05-31
PH23695A (en) 1989-09-27

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